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Wiley


Over-the-counter head lice treatments are likely to fail

A recent review found that over-the-counter head lice treatments have declined in effectiveness, likely due to widespread use leading to pyrethroid resistance. Prescription products such as malathion and spinosad are safer alternatives with proven efficacy.

SourceWiley·JournalPediatric Dermatology·DateSep 6, 2016

Walking a tightrope: Regulators balancing need for safety and flexibility in approvals for new medicines

The European Medicines Agency's approval process for biosimilars shows variability, but offers insights into implementation. Regulators must balance the need for safety with flexibility to support innovation in new therapies, including personalized treatments and products on the borderline between medicines and other sectors.

SourceWiley·JournalBritish Journal of Clinical Pharmacology·DateAug 31, 2016

New research sheds light on how aged wine gets its aroma

A team of researchers has identified an enzyme that plays a crucial role in the formation of compounds giving aged wines their distinct aroma. The discovery, published in New Phytologist, sheds light on how common plant molecules are transformed into specific odorants in wine.

SourceWiley·JournalNew Phytologist·DateAug 29, 2016

Study examines 'weekend effect' in emergency surgery patients

A new study assessed the 'weekend effect' in emergency general surgery patients, revealing a significant reduction in mortality rates from 5.4% to less than 2.9% over 15 years. The study found great improvements in outcomes overall and notable differences in care provided within the week and at the weekend.

SourceWiley·JournalBJS·DateAug 15, 2016

DASH diet may help prevent gout flares

A new study published in Arthritis & Rheumatology suggests that the DASH diet can effectively lower blood levels of uric acid, a known trigger of gout. The DASH diet, which emphasizes fruits, vegetables, and whole grains, was found to lower uric acid by an average of 0.35 mg/dL.

SourceWiley·JournalArthritis & Rheumatology·DateAug 15, 2016

Combat exposure may jeopardize the behavioral health of women in the military

A recent study found that combat exposure among Army enlisted women was associated with an increased likelihood of developing post-traumatic stress disorder (PTSD), depression, and at-risk drinking after deployment. Women with combat exposure were 20 times more likely to screen positive for PTSD compared to those with no exposure.

SourceWiley·JournalJournal of Traumatic Stress·DateAug 2, 2016

Many physicians still prescribe controversial drug combination

A significant number of patients on clopidogrel therapy are also prescribed proton pump inhibitors (PPIs) omeprazole or esomeprazole, increasing the risk of cardiovascular events. Despite regulatory warnings, many physicians have continued to prescribe this combination.

SourceWiley·JournalPharmacology Research & Perspectives·DateAug 2, 2016

Brazil faces major challenges in liver transplantation

Brazil performs more liver transplant surgeries than Latin America and globally ranks third in absolute terms. However, the country's increasing population and inadequate donor organ supply lead to only 5-10 liver transplants per million population annually.

SourceWiley·JournalLiver Transplantation·DateAug 1, 2016

Study finds no link between sleep apnea and joint pain

Research contradicts previous findings that link poor sleep quality to joint pain, instead showing no association with obstructive sleep apnea. The study highlights the need for further investigation into the relationship between pain and sleep apnea.

SourceWiley·JournalArthritis Care & Research·DateAug 1, 2016

Lessons learned from 'The Biggest Loser' study

A recent study on 'The Biggest Loser' television series found that participants regained much of the weight they lost, with suppressed metabolism. Experts say a 5-15% weight loss is unlikely to lead to such large effects on metabolism and emphasize the importance of long-term lifestyle changes.

SourceWiley·JournalObesity·DateAug 1, 2016

New lipid-lowering drugs help patients reduce LDL cholesterol

Researchers found that adding anti-PCSK9 antibodies to existing treatments can significantly reduce LDL cholesterol levels in patients. The studies demonstrated a reduction in LDL cholesterol and achieved high response rates for both alirocumab and evolocumab.

SourceWiley·JournalBritish Journal of Clinical Pharmacology·DateAug 1, 2016

New rare species of whale identified

A new rare species of beaked whale, smaller and darker than Baird's beaked whale, has been identified with a range in the remote North Pacific Ocean. The elusive whale is about 25 feet long and rarely seen, even by Japanese whalers.

SourceWiley·JournalMarine Mammal Science·DateJul 28, 2016

High fat diet improves cartilage repair in mice

A high fat diet and increased body weight do not impair but may even accelerate cartilage repair in a mouse model. The study's findings suggest that the mechanism behind this phenomenon is related to inflammatory and metabolic changes.

SourceWiley·JournalJournal of Orthopaedic Research®·DateJul 19, 2016

Beware of antioxidants, warns scientific review

Antioxidant supplements have been linked to cardiovascular disease, cancer, diabetes, and other conditions due to their impact on oxygen radicals. However, the review suggests that targeting specific sources of oxygen molecules may be a more effective approach.

SourceWiley·JournalBritish Journal of Pharmacology·DateJul 19, 2016

Risk of low blood sugar differs among similar diabetes drugs

A new systematic review found that gliclazide confers the lowest risk of hypoglycemia when added to metformin. This suggests prescribing a medication with a lower risk of low blood sugar may be a rational and affordable alternative for patients with type 2 diabetes.

SourceWiley·JournalBritish Journal of Clinical Pharmacology·DateJul 19, 2016

In corneal transplantation, men and women don't see eye to eye

A recent study published in the American Journal of Transplantation found that gender matching is crucial for successful corneal transplants. Women who receive male donor corneas are more likely to experience rejection and failure, with a higher proportion of mismatched grafts failing or rejecting compared to female-to-female transplan...

SourceWiley·JournalAmerican Journal of Transplantation·DateJul 14, 2016