Articles tagged with Biopsies
Two studies presented at AUA 2008 found that active surveillance is a viable option for low-risk prostate cancer patients. The studies highlighted the importance of reliable clinical predictors of disease progression and showed that endorectal MRI was the most reliable predictor of disease progression.
A study published in Archives of Dermatology found that larger skin lesions (over 6mm) are more likely to be melanoma. The findings support the use of diameter guidelines for screening, but also suggest that smaller lesions can still be malignant.
Researchers present data on gene-based blood testing that may help reduce immunosuppression and predict cardiac allograft rejection. Non-invasive molecular testing of routine blood samples provides information on the immune, inflammatory, and injury status of transplanted hearts before tissue damage occurs.
Researchers found that COX-2 expression is a marker for cancer development in some benign breast biopsies, with higher levels associated with increased risk. The study's results may lead to targeted treatments using COX-2 inhibiting agents.
A new study found that improved biopsy techniques have reduced the correlation between prostate-specific antigen (PSA) levels and positive biopsy results in men with a normal digital rectal exam. The study suggests that PSA tests are less useful for prostate cancer screening, highlighting the need for new diagnostic markers.
A study of post-menopausal women found that hormone therapy increased the risk of abnormal mammograms and breast biopsies, while also decreasing the effectiveness of these methods for detecting breast cancer. The therapy may delay diagnosis and increase breast density, which can lead to a higher risk of breast cancer.
Researchers discovered a correlation between pre-treatment biopsy samples and post-treatment positive biopsies in high-risk prostate cancer patients. This information can help doctors tailor radiation treatment to reduce recurrence rates.
A recent study by the Hadassah-Hebrew University Medical Center found that only one out of 63 patients with complex fibroadenomas had a malignancy. The researchers concluded that these lesions can be treated similarly to simple fibroadenomas, allowing for non-surgical follow-up.
The PEM/PET system can spot tumors half the size of standard imaging systems, and complete an image and biopsy in a similar time frame. It features high-resolution PET images of the breast, guiding needle biopsies with a robot arm.
A new microscope technique offers real-time analysis of breast cancer biopsies, which could reduce the number of needle biopsies needed from women suspected of having breast cancer. The technique uses reflectance confocal microscopy to examine tissue samples and detect cancer cells in minutes.
Over two decades, a study in the UK found that ultrasound-guided liver biopsy is the preferred method due to its reduced complications. The majority of biopsies were performed on patients with raised liver tests and hepatitis C infection.
A new study suggests that an ultrasound-guided fine needle biopsy technique can accurately detect cancer in lymph nodes with a false positive rate of only one percent. The method has been shown to be highly accurate and may reduce the need for unnecessary sentinel node operations.
Current studies show promise in reducing malignancies with 5-alpha reductase inhibitors and dietary fat impact on disease development. Other compounds like soy, selenium, and green tea offer additional possibilities for disease prevention.
A third of prostate biopsies detected cancer, with the risk increasing with each subsequent biopsy. Gene variants influencing innate immunity also linked to improved or poorer lung cancer survival in white patients. Brain tumor stem cells susceptible to a cancer-killing virus, offering new treatment hope.
A study found that combining endobronchial ultrasound (EBUS) and electromagnetic navigation bronchoscopy (ENB) increases diagnostic yield in peripheral lung lesions. The procedure achieved a sensitivity comparable to surgical biopsies, with a 88% diagnostic yield, while reducing complications.
Researchers found that following ultrasound diagnosis of probably benign breast masses is a safe alternative to biopsy for stable masses. The study showed an overall negative predictive value of 99.8%, indicating only 0.2% risk of cancer development.
A recent study of 583 children born after preimplantation genetic diagnosis (PGD) found no significant increase in major malformations compared to those born after conventional IVF. The average birthweight and length of pregnancies were comparable to those born after IVF, providing reassurance about the safety of PGD.
A study from the University of Chicago Medical Center found that African-American men radically underestimate the likelihood of a cancer diagnosis after a needle biopsy for suspected prostate cancer. This underestimation can lead to delayed diagnoses and poorer outcomes.
A new study developed a simple marker that allows urologists to identify men at risk for high-grade prostate cancer, even after a negative initial biopsy. This finding could reduce overtreatment and unnecessary biopsies while improving patient outcomes.
The AlloMap test has been shown to correlate with oxygen saturation levels, cardiac filling pressures, and the electrical properties of the transplanted heart. Non-invasive blood tests can also detect cytomegalovirus-induced immune responses in lung transplant patients.
A study by Duke University Medical Center researchers found that obese and overweight men are more likely to have aggressive prostate cancer than biopsy results indicate. This discrepancy may lead to inadequate or inappropriate treatment, emphasizing the need for more accurate biopsies.
A new procedure, anal cytology, detected abnormal cell changes in 244 HIV-positive patients, leading to subsequent biopsy confirmations. Abnormal results prompt further investigation and management.
A VA researcher has developed a method to identify men at risk for high-grade prostate cancer, reducing the need for unnecessary biopsies. The study found that a high PSA adjusted for prostate size and Gleason scores above 7 indicate a higher risk of life-threatening prostate cancer.
A new study found that a series of simple blood tests can accurately diagnose liver fibrosis in patients with chronic hepatitis C. The FibroIndex was more accurate than two other indices and showed promise as a non-invasive alternative to liver biopsy.
A new study finds that hypnosis can significantly reduce pain and anxiety during breast biopsy procedures, while also shortening procedure time and cost. Women who received self-hypnotic relaxation coaching reported improved coping tools for future waits and work-ups.
A new ultrasound technique, elasticity imaging, has been found to correctly identify both cancerous and harmless breast lesions in nearly all cases. By gauging tissue movement, the non-invasive method can detect how soft or stiff an object is, reducing the need for invasive biopsies.
Researchers found that a man's PSA velocity, or rate of increase in PSA levels, can accurately predict tumor aggression and danger. Men with lower PSA velocity have a 92% chance of not dying from prostate cancer within 25 years.
A 3D ultrasound scanner developed by Duke University engineers successfully guides a surgical robot to pinpoint targets in real-time. The technology has the potential to enable surgeries to be performed without surgeons, especially in remote locations or space stations.
Research at Mayo Clinic found that 16% of men experience moderate or higher pain during prostate biopsies, with the injection of lidocaine causing more pain than ultrasound insertion. The location of biopsy, specifically the prostate apex, is a significant predictor of pain scores.
A core needle biopsy sample gives a representative picture of gene expression in the entire tumor, according to a new study. The results show that biopsy samples have identical gene expression levels as surgical samples, but with four specific genes modified by the biopsy procedure.
A simple blood test can indicate the presence of non-alcoholic steatohepatitis by measuring caspase 3-generated cytokeratin-18 fragments. This test has shown high sensitivity and specificity in differentiating NASH from non-NASH in patients with suspected NAFLD.
A study found that biopsy procedures doubled a woman's chances of becoming pregnant during the next round of IVF. The researchers suggest that mild distress from the procedure may provoke a response making conditions in the uterus favorable for implantation.
This study found that pediatric liver transplant patients develop chronic hepatitis, characterized by increasing fibrosis and autoantibody production. Regular monitoring of autoantibodies is necessary for early detection.
A study published in the Journal of the National Cancer Institute found that sentinel lymph node biopsy resulted in better arm function, improved quality of life, and faster recovery times compared to standard axillary lymph node dissection. Women who underwent sentinel lymph node biopsy had a low recurrence rate and equivalent surviva...
A new study found that using a low radiation dose of 30 mAs can achieve high technical success rates for interventional procedures such as biopsies and catheter placements. The study showed that with minimal image quality, procedures can still be successfully performed.
The study found that more than 60% of patients experienced a change in their treatment plan due to biopsy results, while as many as 75 unnecessary kidney removals were potentially avoided. The image-guided biopsy technique showed higher success rates compared to old techniques, allowing for better tissue sampling and accurate diagnosis.
A new study suggests that renal biopsy can help patients avoid kidney removal by identifying benign tumors that don't require surgery. The procedure is safe and effective, with only minor complications reported in the 407 biopsies performed.
Researchers developed a risk calculator that uses various statistical tests to analyze biopsy results, family history of prostate cancer, race, age, rectal examination results, and previous biopsy history. The model can help patients and physicians decide whether a prostate biopsy should be performed.
The VELScope device emits blue light, causing cells to absorb energy and re-emit fluorescence, helping dentists detect abnormal tissue. The device correctly identified all normal biopsies and 98% of cancers, offering a promising solution for early oral cancer detection.
A recent study published in Radiology found that nearly a quarter of benign papillary breast lesions were upgraded to atypical ductal hyperplasia or ductal carcinoma in situ after surgical excision. This suggests that these lesions should be surgically removed to prevent potential cancer development.
Researchers use MRI to visualize individual immune cells in live animals, enabling real-time tracking of organ rejection. The new approach offers personalized care and reduces biopsy procedures.
The consensus panel recommends minimizing open surgical biopsies in favor of minimally invasive needle breast biopsies, which can help reduce complications and costs. They also suggest using sentinel lymph node biopsy and MRI for accurate staging and diagnosis.
Lowering PSA cutoff from 4.0 ng/mL to 2.5 ng/mL would call for more biopsies, with 10.7% of US men aged 50-59 and 17% of those aged 60-69 affected.
A Mayo Clinic study found that breast biopsy utilization rates remained stable over a 12-year period despite the introduction of new technologies. The study also showed that the ratio between malignant and benign results remained stable at one malignancy for every 2.2 benign results.
A minimally invasive core-needle biopsy guided by CT scans or ultrasound appears to be an effective way to obtain tumor samples, replacing surgery. The technique shows high accuracy rates for diagnosing childhood cancers, with a sensitivity of 97% and specificity of 100%, according to St. Jude Children's Research Hospital researchers.
The study analyzed data from a randomized, prospective trial to determine the effectiveness of PSA testing. Researchers found that no single cutoff value would simultaneously yield high sensitivity and specificity, highlighting the need for re-education on the concept of 'normal' PSA levels.
A study of 23 pancreatic biopsies found ultrasound-guided biopsies to be effective in obtaining adequate samples, with a diagnosis possible in 61% of cases. The procedure is easier on patients than traditional endoscopic biopsies, which require sedation and are less efficient.
Researchers found that dutasteride suppresses blood flow in benign prostate tissue, enabling targeted biopsies to detect cancer more effectively. This reduction in benign blood flow improved cancer detection rates and may reduce the need for repeat biopsies.
Researchers at Oregon Health & Science University developed a nomogram to identify men with high-grade prostate cancer and those who can be closely monitored. The chart uses clinical variables such as age, digital rectal exam findings, and PSA density to predict tumor grade, reducing the need for biopsies.
Low-grade DCIS lesions can evolve to invasive breast cancer within 15 years of diagnosis, with a regional risk and high mortality rate. The study found that 30% of women with untreated low-grade DCIS developed invasive breast cancer in the same breast within 15 years.
AlloMap molecular expression testing enables proactive monitoring of immune system signals, identifying rejection before it occurs. This non-invasive technology eliminates the need for frequent biopsies, improving individual patient outcomes and reducing patient discomfort.
Researchers analyzed 403 sonograms of solid masses, finding that the BI-RADS lexicon descriptors were highly predictive for both malignant and benign masses. Descriptors like circumscribed margins were accurate in 90% of instances for benign lesions.
A massive study is examining prostate cancer screening practices to determine their impact on death rates. The study follows 75,000 men, half of whom are screened and half receive conventional care, allowing researchers to compare survival rates.
A recent pilot study found that only a minority of subjects received a diagnostic work-up according to published algorithms, and that larger nodule sizes were associated with lower use of biopsy for follow-up. Only 7% of subjects diagnosed with lung cancer within a year of the first positive screen.
Researchers analyzed 191 untreated follicular lymphoma patients and developed a model that divides patients into four groups with disparate average survival rates. The model uses gene expression patterns from non-malignant immune cells to predict patient risk, suggesting new therapeutic approaches.
Researchers have developed thin fiber-optic probes that can be threaded through biopsy needles to ensure accurate targeting and diagnose breast cancer with over 90% accuracy. The technology holds potential to minimize trauma and improve procedure speed.
A study published in NEJM found that rapid rise in PSA levels prior to diagnosis is a stronger indicator of prostate cancer death than the actual PSA level. Early and annual testing are recommended for men with high PSA velocity to detect potential aggressiveness of cancers.
Researchers are developing a new technology that uses fiber-optic probes to analyze tissue properties at the needle tip during breast biopsies. The probe can provide structural information, increasing the likelihood of taking a sample from the correct site and potentially reducing missed diagnoses.
Researchers discovered that donor-derived bone marrow cells can differentiate into human endometrial tissue, contributing to endometrial regeneration. This finding may lead to new treatments for uterine disorders like infertility, abnormal bleeding, and cancer.
Researchers found four distinct risk groups and seven independent risk factors for prostate cancer detection, including abnormal exam findings, age, family history, and PSA density. Men with high-risk features remain at risk despite multiple negative biopsies, emphasizing the need for vigilant follow-up.