Articles tagged with Biopsies
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Researchers found that fine needle aspiration is highly sensitive for diagnosing lung cancer, but has a high rate of false negatives, especially in larger lesions. The study recommends repeat imaging to monitor for growth and suggests this method can help patients avoid unnecessary surgery.
Researchers implemented a new CT imaging protocol for lung-nodule biopsies, reducing the radiation dose by 66% while maintaining image quality. The study focused on minimizing patient exposure and promoting safer procedures.
A recent study published in Liver Transplantation confirms that ultrasound-based transient elastography is an effective diagnostic tool for detecting cirrhosis caused by recurrent hepatitis C following liver transplantation. The non-invasive technology offers quick and painless assessment, with high sensitivity and specificity estimates.
A pilot study shows promise for analyzing bladder pain syndrome by analyzing cells shed into the urine, providing a noninvasive alternative to bladder biopsies. The results show distinct gene signatures for inflammation in patients with Hunner lesions, similar to those found in previous studies of bladder biopsies.
A recent study suggests that surgical breast biopsies are not overused, with the actual rate falling between 2% and 18%. The study analyzed Medicare data from 2004 to 2009 and found a true surgical breast biopsy figure of around 11%. This finding challenges earlier reports that suggested surgery was used for 30% of breast biopsies.
A new classification for diagnosing fibrosis in patients with chronic HCV has shown to be as accurate as currently used algorithms, but required no further liver biopsy. The study combined two fibrosis tests, providing a non-invasive and more precise fibrosis diagnosis.
Researchers at Duke University Medical Center found that noise-cancelling headphones playing classical music reduce pain and anxiety during prostate biopsies. This simple and inexpensive method may help an estimated 700,000 US men who undergo a biopsy a year.
A study found that biopsy referral rates for men with high PSA levels remained stable despite recent recommendations to lower the threshold. Biopsies became slightly less common over time, likely due to growing awareness of overdiagnosis and overtreatment.
Researchers suggest combining PSA testing with factors like prostate size, weight, and family history to identify aggressive cancers and avoid unnecessary biopsies. This approach could potentially save up to a quarter of men from undergoing biopsies and related risks.
A new molecular imaging probe using ghrelin exploits the hunger hormone's unique consumption pattern by malignant prostate cancer cells. The test showed the signal was almost 5 times stronger in malignant cancer cells than in normal or benign cells.
A new study shows that comparing a new biopsy of recurrent breast cancer with the original biopsy can dictate a change in treatment. The results suggest that patients may benefit from asking their physician if a second biopsy is needed to confirm their treatment therapy.
A new study explores whether a polarized filter can enhance colposcopy, allowing doctors to detect early signs of cervical cancer more accurately. The approach has shown promise in reducing unnecessary biopsies and surgeries, particularly in young women where normal cell types can be difficult to distinguish.
A Mayo Clinic study has found that a baseline PSA test in men aged 40-60 can predict the risk of subsequent and low-risk prostate cancer. The study, which followed over 600 men for prostate outcomes, showed that men with elevated PSA levels were more likely to undergo biopsies and be diagnosed with low-risk cancer.
Researchers at Johns Hopkins Medicine found that oxaliplatin, a widely used chemotherapy drug for colorectal cancer, causes permanent nerve damage in some patients. A new study suggests using simple skin biopsies to track nerve cell degeneration and develop new treatments to prevent or slow the damage.
A study by Johns Hopkins researchers found a significant rise in serious prostate biopsy complications requiring hospitalization among Medicare beneficiaries. Hospital admission rates were two-fold higher among those who underwent a biopsy compared to controls, with infection-related complications on the rise since 2000.
A new study from the University of Michigan Comprehensive Cancer Center confirms that sentinel lymph node biopsy is a safe and effective way to determine the status of regional nodal basins for head and neck melanoma patients. The procedure was found to be accurate in identifying cancerous nodes, with only 4% false-negative results.
A new urine test can help identify men at high risk of clinically significant prostate cancer, potentially delaying or avoiding needle biopsies. The test supplements an elevated PSA screening result and combines genetic markers to predict cancer presence.
A study found that most US patients with celiac disease have insufficient small intestine biopsy samples, affecting diagnosis. The research suggests that taking more than two biopsy samples can increase the correct diagnosis rate sevenfold.
Elastography and serum markers are non-invasive diagnostic options reviewed in an editorial, showing promise in detecting liver fibrosis. The use of diagnostic liver biopsy is declining due to its limitations, and these alternatives may be more advantageous to patients.
A study published in the Journal of the American College of Surgeons found shave biopsies to be a safe and accurate method for initial evaluation of melanoma. The study analyzed 600 consecutive patients who underwent shave biopsies, revealing that 97% of the results were accurate in determining T-stage and depth data.
A new study shows that nearly 70% of men with rising PSA levels and subsequent normal biopsies were eventually diagnosed with prostate cancer. Rising PSA velocity over several years should prompt clinicians to follow patients more closely, even with negative biopsy results.
A study found that biopsies and patient-provided specimens revealed dermatitis, excoriation, and ulceration but not objective evidence of skin infestation in patients with delusional infestation. Skin inflammation may trigger delusional symptoms in susceptible individuals.
A new technology fusion of MRI with real-time 3D ultrasound improves targeted biopsy accuracy for prostate cancer diagnosis. The system identifies suspicious areas in the prostate and provides a roadmap for biopsy needle guidance, increasing cancer detection rates by five times compared to conventional biopsies.
The Society of Interventional Radiology prioritizes patient safety through education and research on radiation dosage reduction. New articles explore techniques to optimize radiation use without compromising quality care.
A new study suggests that less invasive lymph-node biopsy can accurately diagnose lymph node status in patients with early stage endometrial cancer, reducing the risk of surgical complications. The procedure has been shown to be safe and effective, with a negative predictive value of 97% and sensitivity of 84%.
A new study found that taking bosentan did not improve health outcomes for patients with idiopathic pulmonary fibrosis (IPF). Researchers suggest a subset of IPF patients may still benefit from the drug, but further studies are needed to confirm this.
A new PSA test has been shown to detect aggressive prostate cancer more accurately than current tests and reduce unnecessary biopsies. The Pro-PSA test uses a specific PSA subform called (-2) Pro-PSA and can be analyzed with a mathematical formula to provide an overall Prostate Health Index.
A pioneering study shows tissue-engineered urethras, made with the boys' own cells, are functional and viable within 3 months. The grafts have lasted at least six years and maintained adequate outflow, offering a new alternative for reconstruction.
Researchers found that PSA velocity is a poor predictor of prostate cancer and may lead to unnecessary biopsies. The study, which analyzed data from over 5,000 men, suggests that using changes in PSA levels as a basis for recommending biopsy can result in many unnecessary procedures.
Research suggests that PSA velocity is a poor predictor of prostate cancer and can lead to unnecessary biopsies. The study found that men with rapid rises in PSA levels did not have cancer more often than those with slower rises, highlighting the need for alternative screening methods.
Researchers found ultrasound fusion imaging to be safe and effective in detecting bone and soft tissue cancers, with 93% accuracy compared to CT biopsies. The technique guides a needle biopsy with precise accuracy, making the experience more convenient for patients.
Using microbubbles and ultrasound can help determine treatment for early breast cancer patients, reducing the need for additional surgeries. The study found that microbubble contrast-enhanced ultrasound accurately identified sentinel lymph nodes in 89% of patients.
Michigan State University researchers have developed smart laser technology that can identify molecules in skin cancer without cutting away tissue. This technology, published in Nature Photonics, enables rapid, non-invasive scanning and may help reduce the time required to develop new drugs.
A new ultrasound technique, elastography, can accurately predict cancer in patients with BI-RADS category 4 masses by measuring tissue softness. The study found an 79% accuracy rate in identifying cancer, suggesting that this method could reduce unnecessary breast biopsies.
A Swedish study found that PSA screening nearly halves prostate cancer mortality after 14 years. However, the screening was associated with a risk of impotence and urinary incontinence, albeit at lower rates than expected.
Scientists from deCODE genetics and academic colleagues report discovering genetic markers that impact individual baseline levels of prostate-specific antigen (PSA). Analyzing four SNPs in tandem with genetic risk factors detected by the deCODE ProstateCancer test yields substantial improvement in PSA screening efficacy.
Researchers developed an imaging technology that uses ultrasound to accurately identify tumors and assess their aggressiveness. This can lead to better treatment and cost savings in healthcare.
Active surveillance outperforms initial treatment for low-risk prostate cancer, providing a higher quality-adjusted life expectancy (QALE) and reducing adverse effects of treatment. The optimal strategy depends on individual patient preferences for surveillance or treatment.
A study presented at the Radiological Society of North America annual meeting found that diagnosis uncertainty can be as stressful as knowing a serious illness, with breast biopsy patients reporting significantly higher anxiety levels. Healthcare providers can alleviate patient stress by improving communication and shaping expectations.
Researchers at the University of Alberta have developed a new method to analyze biopsies from heart transplant patients by examining their genes, allowing for early prediction of treatment success. This approach uses software algorithms to reduce data to key numbers necessary for diagnosis and prognosis.
The European Society of Human Reproduction and Embryology has published new guidelines for Preimplantation Genetic Diagnosis (PGD). The guidelines cover the organization of PGD centers, laboratory methods, clinical protocols, and follow-up recommendations. PGS is also included in the guidelines.
A new study uses a combination of computed tomography (CT), postmortem CT angiography (CTA) and biopsy to determine the natural causes of death, with results showing near-identical findings in 18 out of 20 cases. The minimally invasive approach has improved accuracy and reduced the need for traditional autopsy.
A Rutgers-led research team has received a $3.3 million NIH grant to develop technology that combines advanced ultrasound and magnetic resonance images to pinpoint cancerous tissue during biopsies. This could lead to more accurate diagnoses and reduced false negatives.
A recent study published in the American Journal of Roentgenology found that the incidence of serious infection after common ultrasound-guided procedures is low. The researchers reviewed 13,534 procedures and reported only 14 procedure-related infections, with nearly all patients improving on antibiotics alone.
A study found that kidney transplants showing fibrosis and inflammation after one year are at increased risk of long-term transplant failure. Routine biopsies can help identify these abnormal signs and predict potential targets for early preventative treatment.
A study found that men with low-risk prostate cancer often receive aggressive treatment, including surgery or radiation, even if their PSA levels are low. The researchers suggest that lowering the biopsy threshold for men with PSA levels below 4 nanograms per milliliter could lead to an increase in unnecessary treatments.
A new method of tissue banking enables researchers to obtain high-quality RNA samples from lung tumor biopsies, increasing the number and type of tumors available for gene expression studies. This improves personalized medicine prospects for lung cancer patients.
A new diagnostic standard based on serology alone could eliminate the need for intestinal biopsy in diagnosing celiac disease. The study finds that combinations of two serology tests can accurately diagnose or rule out the disorder in over 92% of individuals.
A study found that imaging-guided percutaneous needle biopsies increased by 67% between 1997 and 2008, while open biopsies decreased. The technique offers greater precision and lower complication rates, resulting in a modest growth rate of 3% overall.
Researchers developed a noninvasive combination technique that uses ultrasound-guided optical tomography to distinguish early-stage cancers from benign lesions in the breast. The study found that the technique was effective in identifying malignant lesions with high sensitivity and specificity, particularly in smaller lesions.
The LungPoint System enables accurate and efficient biopsy procedures for diagnosing and treating lung cancer by providing pre-procedure mapping and visual guidance during bronchoscopy. This technology allows physicians to plan their path ahead of time, reducing the need for invasive procedures.
A study found that having a pathologist on-site during ultrasound-guided thyroid biopsies decreased the inadequacy rate from 13.5% to 5%. This improvement could reduce repeat biopsy rates by up to 60%, making more efficient use of resources. The study recommends using on-site pathology for large numbers of thyroid biopsies.
Researchers found a gene expression test reduced biopsies and was safe, resulting in similar two-year outcomes as traditional biopsies, and was preferred by patients. The test measures 11 genes associated with heart transplant rejection, reducing the need for invasive heart muscle biopsies.
A new blood test has reduced the number of biopsies performed on heart transplant patients by 50% in a landmark Stanford study. The test uses genomics technology to identify patients at low risk for rejection, allowing doctors to safely reduce biopsy frequency and improve patient quality of life.
A new endoscopic scanning technique called EPSS has been developed to detect dysplasia in Barrett's esophagus, a precursor to esophageal cancer. The technique uses polarized light scattering spectroscopy to identify cellular changes on a subcellular scale, enabling early detection and potentially improving treatment outcomes.
A study found that Wilson disease patients' liver histology progression does not correlate with clinical parameters or treatment type. Researchers recommend considering liver biopsy with hepatic copper quantification every 3 years due to the inability of clinical tools to detect fibrosis progression despite treatment.
A four-year international trial found that dutasteride reduced the chances of being diagnosed with mid-range aggressiveness tumors, which account for most prostate cancers. The drug was effective at reducing the risk of medium-grade tumors by 31.4% in men with a family history of prostate cancer.
A new virtual biopsy probe system has shown high accuracy in detecting precancerous polyps during colonoscopy, with a success rate of 91%. The system uses Confocal Laser Endomicroscopy to magnify cells and detect changes that may indicate cancer. This technology could potentially eliminate the need for biopsies in some patients.
A study published in the American Journal of Roentgenology found that the risk of major bleeding after image-guided percutaneous biopsies is low, even among patients taking aspirin. The study reviewed 15,181 biopsies performed over six years and found only 70 hemorrhages (0.5%) within three months of biopsy.
Patients with non-alcoholic fatty liver disease (NAFLD) have a higher overall mortality rate compared to the general population. The study found that cardiovascular disease and extra-hepatic malignancies were the primary causes of death among NAFLD patients.