Articles tagged with Cancer Treatments
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A study found that rural physicians in Arizona estimated they could increase their endoscopic procedures by 53.1%, while urban physicians estimated an additional 35.7% with improved compensation. The potential increase is attributed to the growing population of older individuals moving to warmer climates.
Despite high awareness, African-Americans are underrepresented in HPV vaccination due to misinformation, lack of education, and societal pressures. The survey found that most participants believed the vaccine was safe and effective, but caregivers were often unaware of its benefits.
The ELLA Binational Breast Cancer Study reveals significant differences in breast cancer risk factors between Hispanic and non-Hispanic women. Hispanic women are at a higher risk of triple-negative breast cancer due to family history, while those born in Mexico exhibit increased risk due to geography and environment.
Survivors of early-stage lung cancer who engage in regular physical activity experience improved mood, vigor, and physical functioning. Moderate exercise, such as brisk walking a few times a week, may promote better quality of life and reduce depressive symptoms.
Researchers discovered that atypical spitzoid tumors (ASTs) respond well to treatment, with 27 patients experiencing complete remission after a lymph node biopsy. The study suggests ASTs behave differently from other types of melanoma and may not be as aggressive.
A new study confirms that estrogen and progesterone increase the risk of breast cancer more than estrogen alone. The study suggests a two-year safe period for hormone replacement therapy.
A clinical decision model using MR spectroscopy can help patients avoid unnecessary biopsies and treatments by identifying whether a new lesion is due to a recurrent tumor or post-radiation changes. The technique analyzes ratios of three metabolites, including choline, creatine, and NAA, to determine the likelihood of a recurrent tumor.
Scientists have discovered a link between chronic inflammation and colon cancer, with the Stat3 protein playing a crucial role in tumor development. The study found that stimulation of Stat3 by inflammatory chemicals promotes cell survival and growth, leading to increased colonic tumor incidence.
The University of Pittsburgh Graduate School of Public Health has been awarded a seven-year $11 million grant to coordinate the Hepatitis B Clinical Research Network, a consortium of 15 US and Canadian institutions. The network will conduct translational research on hepatitis B, aiming to find a lasting cure for the infection.
Lifetime risk of alcohol-use disorders for men exceeds 20% and women less than half that, with 15% at risk for abuse and 10% for dependence. Effective recovery strategies exist and can begin with doctor visits.
The University of Texas at San Antonio has received a $1.2 million gift to purchase an aberration-corrected electron microscope, one of only two worldwide. This instrument will aid researchers in developing new cancer therapies and treatments, while also advancing research globally across various disciplines.
Two studies identified a novel biomarker for metastatic bladder cancer and discovered stem cell factor's role in airway remodeling in asthma. Additionally, researchers found that Staphlococcus aureus beta-toxin causes lung injury in pneumonia, while rosiglitazone may reduce the severity of scleroderma.
Researchers have found that certain measles virus vaccine strain derivatives can effectively infect, replicate in and kill prostate cancer cells. This type of treatment, called virotherapy, shows promise as a potential cure for locally advanced or metastatic prostate cancer.
Cachexia is a wasting disease that can be life-threatening if left untreated. It's often linked to an underlying disease and requires specialized care from a physician familiar with the condition.
A study examines racial disparities in survival among black patients diagnosed with early-stage lung cancer. Despite recommended treatment, black patients have lower five-year survival rates compared to white patients.
The special issue highlights various new treatment options, including mobile phones, Internet-based interventions, and computers. Researchers have seen promising results, such as a high number of students logging on to screening programs and increased access for hard-to-reach populations.
Researchers have determined the three-dimensional structure of TIGAR, an enzyme that helps regulate energy production in cells. The discovery may lead to earlier cancer detection or preventative treatments.
Research suggests that genetic variations in DNA repair patterns can predict a threefold increased risk of pancreatic cancer, while others may decrease it by up to 77 percent. The study analyzed nine single nucleotide polymorphisms among patients with and without pancreatic cancer.
Researchers have identified a mechanism for an effective immune response to brain tumors by combining immunotherapy and strategies to kill tumor cells. The study suggests that this combination may provide effective treatment for glioblastoma multiforme, the most aggressive form of brain cancer.
A genome-wide study has identified a new subtype of childhood acute lymphoblastic leukemia associated with a poor treatment outcome. The study found that patients with this subtype have a high relapse rate and poor disease-free survival, highlighting the need for further research and treatment options.
Researchers have shown that maslinic acid significantly inhibits cell proliferation and induces apoptosis in colon-cancer cells. The compound may provide a cheap and effective way to control colon cancer and is being investigated as a potential chemotherapeutic agent.
Researchers are studying the mechanisms behind cytomegalovirus-induced cell death in the retina, which may lead to new treatment targets. Understanding this process could also provide insights into how the retina responds to other insults such as diabetes or infection.
Researchers found that silencing of a crucial gene in lung cancer leads to impairment in genome-wide changes, contributing to cancer development and progression. Tobacco use is strongly linked to modification of the MTHFR gene, which triggers global hypomethylation and deregulation of DNA synthesis.
A study by researchers from the University of Kentucky found that grape-seed extract induces apoptosis in leukemia cells by activating the JNK pathway, leading to cell cycle regulation and death. The extract has shown promise as a potential agent for preventing or treating hematological malignancies.
Researchers developed a method to analyze genetic variations in HCV-infected patients, predicting their response to antiviral therapy. This approach may lead to a test that identifies targets for new antiviral drugs.
Researchers developed an approach that predicted treatment response by analyzing genome-wide amino-acid sequence variation in HCV-infected patients. The data has implications for developing a predictive test to identify individual responses to treatment, which could help target new antiviral drugs and reduce treatment failures.
Researchers at Memorial Sloan Kettering Cancer Center developed a new generation of microscopic particles, called C dots, that are biologically safe and stable. These particles can be customized to target specific molecules on tumor surfaces, enabling earlier detection and more personalized treatment options.
A new study finds that hospice services are restricted by eligibility criteria that reduce usage among patients who need it most, particularly African Americans. The researchers suggest revising the criteria to prioritize those with greater needs for specific services like pain management.
A UCLA study found that low-income men are more likely to present with advanced prostate cancers, highlighting the need for increased access to screening services. The study also revealed that diagnosis rates for lower-risk cancers did not increase over time among IMPACT patients, unlike in more affluent populations.
A study at University of Rochester Medical Center discovered a gene mutation in the placenta that is also influential in cancer development. The SENP2 gene's role in early embryo development was not known until now.
University of Texas Medical Branch researchers have identified a promising new target for colon cancer therapy by mapping the biochemical pathway critical to the spread of tumors. High levels of the enzyme Akt2 are found in association with other cancers, and its inhibition shows promise in stopping colon cancer's spread.
The five-year study aims to determine which rehabilitation therapies are most successful in improving outcomes for patients with different types and severities of traumatic brain injuries. The researchers will analyze data from over 2,300 patients to identify effective treatments.
A subanalysis of the AZA-001 phase III trial reveals Vidaza extends overall survival and reduces death risk in elderly higher-risk MDS patients. The treatment also improves one-year survival rates in all response categories.
A landmark analysis found that continuous treatment with Revlimid and dexamethasone improved overall survival and time to disease progression in multiple myeloma patients. Patients who continued therapy had significantly longer overall survival rates compared to those who discontinued treatment after 10 months or less.
A new analysis of the AZA-001 phase III clinical trial shows that Vidaza significantly improves response rates for higher-risk MDS patients. Continued treatment with Vidaza leads to improved responses in nearly half of patients, offering hope for those who initially have a weak response.
The ECOG E4A03 study found that Revlimid plus low-dose dexamethasone improved three-year overall survival rates to 75% in the intent-to-treat population. Continuous therapy also achieved a 91% overall response rate with a high complete response and very good partial response rate.
Researchers at University of Leeds have identified a promising new target for hepatitis C treatment: the p7 protein. The study found that genetic variations among HCV strains affect sensitivity to certain drugs, highlighting the need for tailored combination treatments.
An analysis of a phase III clinical trial showed that VIDAZA can improve patient responses, achieving an overall response rate of 51% in higher-risk MDS patients. Continued treatment with VIDAZA led to better outcomes for almost half of responders.
Researchers found identical survival rates among African Americans and white patients after autologous bone marrow transplants. However, African Americans were less likely to receive the treatment due to pre-existing medical conditions and socio-economic factors.
A new global evaluation system for neuroblastoma has been recommended to improve treatment outcomes for children. The system, developed by the International Neuroblastoma Risk Group, will enable quicker identification of optimal treatments and facilitate clinical research.
Researchers are exploring the PI3-kinase pathway's role in cancer, with studies showing its inhibition can suppress tumor growth and cell survival. The pathway is also involved in angiogenesis, differentiation, and cell growth, making it a critical target for novel therapies.
A recent study published in Cancer Research found that Latina women with higher European ancestry are at a greater risk of developing breast cancer. The risk increases by 79% for every 25% increase in European ancestry, regardless of other factors.
A randomized trial found that systematic pelvic lymphadenectomy did not improve disease-free or overall survival in women with stage I endometrial cancer. Lymphadenectomy was associated with improved surgical staging and detection of disease spread to pelvic lymph nodes, but no therapeutic benefit.
A tracking and feedback system reduced racial disparities in adjuvant therapy among women with early-stage breast cancer, increasing consultations with medical oncologists by 14 percentage points. The study found a decrease in underuse of adjuvant treatment, particularly among black and Hispanic women.
Research suggests melatonin therapy may prevent ocular inflammation in uveitis, reducing symptoms and protecting the blood-ocular barrier. Melatonin treatment has anti-inflammatory effects, potentially benefiting patients with chronic uveitis.
A program called Project Early Awareness teaches high school girls about breast health and self-exams, resulting in a 39% increase in comfort with performing a self-exam and a 69% increase in correct answers to breast cancer questions. The goal is for breast self-exams to become routine among young women.
A recent study found that Latina women are 5.6 times more likely to express regret over their breast cancer treatment compared to white women. The researchers discovered that despite similar treatment, Latinas reported higher dissatisfaction and a desire for more culturally tailored information.
Researchers found that calorie restriction and exercise can modify pathways leading to mTOR, a molecule involved in cell growth. Calorie restriction showed more global effects on cell signaling, suggesting it may produce a more potent anti-cancer effect.
A recent study found that individuals with lower socioeconomic status are more likely to be diagnosed with late-stage colorectal cancer, leading to poorer survival rates. The research highlights the importance of removing barriers to healthcare services, including screening tests and treatment for colorectal cancer.
A study published in Clinical Oncology found that funding decisions for cancer patients with exceptional circumstances are influenced by their location rather than their health needs. This has led to a postcode lottery, where some patients receive funding while others do not, despite similar circumstances.
Researchers found that home-based diet and exercise interventions improved physical functioning in older, long-term cancer survivors. Participants in the intervention group demonstrated significant improvements in their diet and exercise behaviors, as well as measures of basic and advanced lower extremity functioning.
ER/PR negative tumors associated with higher risk of poorer prognosis and limited treatment options. African-American women have higher risk due to race, socioeconomic characteristics and other tumor characteristics.
A study found that women with a strong family history of breast cancer but without BRCA1 or BRCA2 mutations are at increased risk for developing the disease. These women had a four-fold higher risk than average, highlighting the importance of genetic testing and preventive measures.
Research identified three genes linked to fat processing that could raise kidney cancer risk, according to a study presented at the American Association for Cancer Research. Variants of nitric oxide synthase 2A and prostaglandin-endoperoxide 2 were found to increase risk, while apolipoprotein E1 was associated with reduced risk.
Researchers studied DNA methylation in former smokers and found differences between those with lung cancer and disease-free individuals. Altered methylation levels may explain why some former smokers develop lung cancer despite quitting smoking.
Researchers have found strong links between smoking and two forms of esophageal cancer, as well as a form of stomach cancer. Drinking alcohol is strongly associated with one form of esophageal cancer, with the risk increasing fivefold for those who drink four glasses a day.
A large clinical trial found that calcium supplementation reduced colorectal adenoma recurrence risk by 32% only in those with low magnesium to calcium ratio. This suggests a personalized diet/supplementation regimen considering both nutrients may be more effective than supplementing with one alone.
A new research study at Cardiff University aims to understand and regulate a patient's immune response to infections, which is crucial for treating end-stage kidney disease. The three-year grant will enable the multidisciplinary team to investigate the consequences of bacterial infection on patients with peritoneal dialysis.
A new study by Indiana University found that young female breast cancer survivors experience significant problems related to sexual arousal, desire, and orgasm. Many reported vaginal dryness, genital pain, premature menopause, fatigue, and fertility issues, highlighting the need for research on strategies to address these challenges.
A study of over 200 cancer patients found that age was not a significant factor in survival rates. Instead, factors like physical quality of life and metastatic dissemination played a crucial role. The findings suggest that older patients should not be excluded from clinical trials due to their age.