Articles tagged with Cancer Treatments
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Researchers identified a genetic marker that predicts response to hepatitis C treatments, revealing a single-letter DNA change near the IL28B gene. This discovery explains why African-Americans and East Asians respond differently to treatment, highlighting individual genetic makeup as a key determinant of response.
Researchers have discovered how the DISC complex triggers cell death or survival by switching key molecules' activity levels. Stopping the DISC from functioning properly prevents efficient cell death, resulting in disease conditions like ALPS.
A new experimental treatment, GIFT15, has been shown to completely reverse multiple sclerosis in mice by suppressing the immune response. The treatment, which combines two proteins, may also be effective against other autoimmune disorders like Crohn's disease and lupus.
A new study published in The Lancet found that adding a TNF antagonist like infliximab to methotrexate treatment improves symptoms for patients with early rheumatoid arthritis who have not responded well to methotrexate alone. This approach can prevent overtreatment and reduce side effects and costs.
A two-year study found that three treatment combinations for clearing the most common form of hepatitis C virus work equally well, with about 40% clearance rates. Researchers also noted that women achieved higher rates of virus clearance with the standard dose of peginterferon alfa-2b.
New DNA and RNA aptamers have shown promise as treatments for various diseases, including macular degeneration and cancer. Their ease of production, stability, and chemical modifications enhance their drug-like properties.
Researchers found that intermittent calorie restriction provided greater protection from mammary tumor development, even with a lower degree of calorie restriction. The study suggests that altering hormone levels, such as insulin and IGF-1, may play a key role in cancer prevention.
A groundbreaking clinical trial has shown that exercise can significantly improve symptoms of fatigue and depression, increase cardiovascular endurance, and maintain quality of life for adult leukemia patients undergoing treatment. The study demonstrated a substantial reduction in total fatigue and depression scores, as well as improve...
Studies reveal that hepatitis C virus carriers have a significant increase in mortality, with liver-related deaths being the leading cause. The research found that monitoring HCV load and ALT levels may be crucial for identifying high-risk individuals, particularly older carriers who are less responsive to treatment.
A study found that S-adenosylmethionine (SAMe) prevents the formation of hepatocellular carcinoma (HCC) in rats, with a 1cm tumor reduced in size after treatment. However, high doses were not sufficient to treat established HCC cases, as the liver compensates for SAMe accumulation by metabolizing it.
The Peninsula College of Medicine and Dentistry has received a grant to study the role of brain tumors in deafness and develop non-invasive therapies. The research aims to identify how tumors grow and cause hearing damage, and test drug-based treatments.
A recent study published in Cancer found that men with early stages of prostate cancer who delay radical treatment have acceptable levels of anxiety and distress. The study's results suggest that living with untreated cancer is not upsetting for many patients, but certain mental and physical factors can increase distress.
Developed a compact gamma camera called ProxiScan to localize prostate cancer tissue with high resolution. The camera system enables early diagnosis and treatment of potentially deadly disease.
UT Southwestern Medical Center researchers have received a $2 million grant to study lung cancer in nonsmokers. They will use a coordinated approach to discover biomarkers and develop a test to detect early-stage lung cancer.
The American Society of Hematology is honoring six scientists for their significant contributions to hematologic diseases, including the diagnosis and treatment of lymphomas and leukemia. The awards recognize pioneering research achievements and outstanding leadership in advancing the field of hematology.
A Purdue University scientist has discovered a key process in cell growth that can lead to the formation of tumors. The research found that an overabundance of the polo-like kinase 1 molecule during cell growth, as well as a shortage of the p53 molecule, will lead to tumor formation.
The American Society of Plastic Surgeons reports nearly 70% of eligible women lack information on breast reconstruction procedures. To address this issue, ASPS is launching an awareness campaign to educate and empower patients to make informed decisions about their care.
Scientists at QIMR have discovered two genes that significantly increase the risk of developing melanoma in people with multiple moles. This groundbreaking research will help develop new screening techniques and potentially lead to new therapies for this deadly skin cancer.
Researchers at the University of Oklahoma Health Sciences Center discovered a natural compound that restores balance in the eye to stop diabetic retinopathy, a disease affecting five million Americans. The treatment prevents leakage, blocks inflammation, and stops unwanted blood vessel growth.
Researchers at Cedars-Sinai have developed a novel gene therapy that uses immune cells to target glioblastoma multiforme. A specific biomarker, HMGB1, has been identified as an effective tool to monitor tumor response to this treatment.
Scientists have found that mechano growth factor (MGF) stimulates muscle development by activating stem cells in response to exercise. MGF has great potential as a therapeutic treatment for age-related muscle loss and diseases such as muscular dystrophy, ALS, and cancer.
A new three-way measurement method has been developed to predict disease metastasis in prostate cancer, combining PSA doubling time, Gleason score, and interval between surgery and detectable PSA levels. This improved prediction method may help determine which patients benefit from additional therapy after surgery.
Biocatalogue.org provides a centralized registry of curated life science Web Services, enabling researchers to discover and use biological tools for treatments of H1N1 flu and cancer. The service is expected to significantly accelerate research in the medical, agronomical, and pharmaceutical fields.
A study published in the Journal of Thoracic Oncology found a significant difference in the quality and type of lung cancer information available online in the US and Japan. The US websites were more likely to discuss standard treatment methods and had stricter ethical policies.
The University of Illinois Chicago is leading a five-year study to increase demand for evidence-based, Internet-based smoking cessation treatment among young adults. The project aims to develop interactive, Internet-based ads and evaluate their effectiveness in motivating young smokers to use the stop smoking program www.BecomeAnEx.org.
Researchers found that ultra-fast freezing of ovarian tissue can achieve the same success rate as fresh tissue in transplants, with a viability rate of 91.9% compared to 88.9%. The cortical grafting technique allows for simpler procedure with equally successful results, enabling women to have children later in life.
Research reveals Alisol B acetate inhibits proliferation of gastric cancer cells and induces apoptosis through mitochondrial and PI3K/Akt signaling pathways. This could lead to the development of a new anticancer agent for treating gastric cancer, one of the most common cancers worldwide.
The UK has launched a £41 million initiative to develop innovative medical solutions for osteoarthritis, aging populations, and imaging technologies. Four new Centres of Excellence will integrate clinicians, biomedical scientists, and engineers to create high-tech treatments.
The AGA Foundation has awarded a $150,000 grant to Dr. Michael Choi for his research on carcinoid tumors, a type of neuroendocrine cancer. This funding will support the development of novel therapeutic approaches to improve treatment outcomes for patients with these rare and often slow-growing cancers.
A recent study suggests that weight-loss surgery could be associated with reduced cancer risk in obese women, with a 42% decrease in first-time cancers over 10 years. However, the surgery had no effect on cancer incidence in men. The findings indicate that bariatric surgery may have broader benefits for women's cancer prevention.
People with schizophrenia are at a higher risk of dying from all causes, including cancer, due to factors like smoking and delayed diagnosis. Cancer mortality rates among schizophrenic patients are significantly higher than those in the general population, particularly for women.
A recent study published in Cancer Prevention Research found that men with prostate cancer who consumed green tea demonstrated a significant reduction in serum markers predictive of disease progression. The study showed a 30% or greater reduction in levels of hepatocyte growth factor, vascular endothelial growth factor, and prostate-sp...
A new online decision tool allows prostate cancer patients to weigh their own preferences against medical data to personalize treatment plans. The tool considers multiple factors, including life expectancy and side effects, to guide treatment decisions.
Researchers evaluated percutaneous radiofrequency ablation (PAA) as an alternative to conventional RFA in treating hypervascular HCC. The study found that PAA significantly reduced post-RFA recurrence and improved treatment outcomes, making it a promising new approach for this patient population.
Three studies confirm etanercept's effectiveness in treating JIA, with improved HRQoL and reduced disease activity. The treatment showed a good safety profile, with most patients experiencing mild adverse events.
Researchers discovered a potential new treatment for muscle atrophy, a debilitating condition characterized by loss of muscle mass and function. Des-acyl ghrelin, an appetite-stimulating hormone, shows anti-atrophic activity on skeletal muscle in mice with muscular atrophy.
Resveratrol shows therapeutic potential in preventing age-related disorders, including neurodegenerative diseases, inflammation, diabetes, and cardiovascular disease. Low doses improve cell survival, while high doses increase cell death.
A study analyzing the mutator hypothesis found that cancer cells' efficient pathways to cancer are often driven by genetic instability, supporting the hypothesis. This discovery has implications for cancer therapy, as it may enable cancer cells to rapidly evolve resistance.
A new clinical trial found that starting antiretroviral therapy (ART) before CD4+ T cell counts drop below 200 cells/mm3 improves survival for HIV-infected adults. The study's results have the potential to change standard of care for HIV infection in dozens of countries.
The X-Suit NIR stent provides flexible construction to fit any biliary duct and is constructed of Nitinol for durability. It has a proprietary NIRflex cell design that offers superior radial support and reduces stress on the tissue, making it ideal for re-establishing biliary flow.
A Henry Ford Hospital study found an association between microRNAs and natural killer T cells, which can lead to autoimmune diseases and cancer. The discovery could pave the way for new treatment therapies for chronic immune diseases.
The AGA Institute will present exciting data on treatments for Clostridium difficile infection, hepatitis C, and Crohn's disease. The late-breaking session includes studies on optimized therapies and new technologies, which may become the standard of care in the near future.
Researchers found that treating gum disease improved rheumatoid arthritis symptoms, including reduced swollen joints and morning stiffness. The study's results suggest a link between periodontal disease and rheumatoid arthritis, highlighting the importance of good oral health in overall well-being.
Researchers at Mayo Clinic have identified a novel molecular path linked to primary biliary cirrhosis, a disease affecting 1 in 2,500 Americans. The study found variants of two genes, interleukin 12A and interleukin 12RB2, strongly associated with the condition.
The American Thyroid Association has developed comprehensive guidelines for diagnosing, treating, and monitoring patients with Medullary Thyroid Carcinoma (MTC), an uncommon form of thyroid cancer. The guidelines cover a range of clinical topics and propose directions for future research.
A new study found that childhood cancer survivors have a significantly increased risk of developing second primary cancers throughout their lives. The research, published in the Journal of the National Cancer Institute, analyzed data from 47,697 people diagnosed with cancer before age 20 and found a higher incidence rate of new primary...
A new clinical discussion tool, GAIN, has been developed to help physicians discuss potential reasons for using long-acting injectable antipsychotic therapies with patients. The tool addresses barriers such as needle phobia and stigma, aiming to increase patient acceptance and adherence.
Scientists use zebrafish to investigate the role of RAS mutations in melanoma formation and progression. The research found that altering signaling pathways can reduce the effects of RAS mutations, providing a potential therapeutic approach.
Research reveals ILK promotes growth in aggressive ARMS cells, while suppressing ERMS cell growth. Targeting ILK may offer therapeutic strategy for ARMS patients.
A new study found that younger men with advanced prostate cancer have a poorer prognosis than older men, despite having less aggressive tumors. The researchers suspect that young men may have biologically more aggressive forms of the disease.
A study found that mice treated with the algae-derived protein Griffithsin had a 100% survival rate after exposure to the SARS coronavirus, whereas untreated mice only survived 30%. The protein alters sugar molecules on the virus's envelope, preventing it from causing disease.
A randomized study found that RISPERDAL CONSTA significantly delayed time to relapse compared to placebo in patients with Bipolar I Disorder. The median duration of treatment was nine months for the RISPERDAL CONSTA group, which had a lower rate of relapse during the double-blind phase.
Researchers at Medical College of Georgia have identified a critical protein called erbin that regulates insulation in the peripheral nervous system. Impaired myelin formation is linked to neurological and psychiatric diseases, while erbin's role in cancer therapy provides a potential new site for targeted treatment.
New studies demonstrate RISPERDAL CONSTA (risperidone) Long-Acting Treatment significantly improves clinical and functional outcomes for patients with schizophrenia. The treatment reduced rates of rehospitalization among patients, especially those with complex medical histories.
RISPERDAL CONSTA has been approved as both monotherapy and adjunctive therapy in the maintenance treatment of Bipolar I Disorder. The medication offers a convenient and effective choice to delay relapse, with studies demonstrating significant delays in mood episode recurrence.
Overall median survival improved from 3.5 months in period A to 12 months in period C, despite stage of disease at presentation affecting survival. Surgical resection is the only curative treatment, but many patients present with advanced-stage disease.
A physicist at Brookhaven National Laboratory has developed a compact and cost-effective gantry design for delivering tumor-killing particle beams, reducing weight and size by up to 100 times. This new design could make precision particle therapy available to more cancer patients worldwide.
The Multicenter AIDS Cohort Study (MACS) has significantly contributed to the scientific understanding of HIV/AIDS through its 25 years of behavioral and biological data. Key findings include identifying unique features of long-term non-progressors, managing HIV treatment, and the link between viral load and progression of HIV disease.
Richard Junghans, MD, has been awarded a $5.9 million grant from the Department of Defense Breast Cancer Research Program to research gene therapy techniques to modify patients' T cells and create 'designer T cells' to fight breast cancer.
Researchers found that patients with chronic hepatitis C who have achieved a sustained viral response often still carry miniscule amounts of the virus in their bodies. These trace remainders are thought to be infectious, posing a risk to others.