Articles tagged with Positron Emission Tomography
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Researchers found that quantitative index adds accurate information about patients' responses to first-line chemotherapy, improving tumor response prediction. This method can also identify disease transformation and shorten treatment for favorable responders.
Researchers aim to improve breast cancer screening by developing new anatomical imaging methods, including MRI and PET, and sensitive histopathologic detection techniques. The goal is to identify precancerous lesions and map their extent for precise surgery.
A new study found that people's responses to placebo treatments are linked to their brain's dopamine activity, particularly in the nucleus accumbens. The study used two types of brain scans to investigate this phenomenon and suggests that individual expectations play a significant role in determining the effectiveness of placebos.
Researchers found a strong correlation between tumor responses during treatment and three months after completion, suggesting PET scans can be performed earlier to modify treatment plans. This could lead to better tumor control and survival rates, potentially changing standard practice guidelines.
A UT study found that cardiac PET-CT scanners incorrectly indicate coronary artery disease in up to 40% of patients due to software flaws. The researchers developed a solution to address the issue, resulting in accurate images of blood flow in the heart.
Researchers from the Alzheimer’s Disease Neuroimaging Initiative (ADNI) report promising early findings on imaging and biomarker analysis. The study reveals improved methods and uniform standards for tracking brain changes and predicting Alzheimer's disease, potentially leading to faster and more efficient evaluation of potential thera...
A study published at SNM's 54th Annual Meeting found that PET/CT imaging detected more sites of disease and identified women whose disease was likely to progress. The technique influenced treatment decisions in 59% of women with recurrent ovarian cancer, improving management outcomes.
Researchers developed a novel imaging technique combining CT and PET scans to detect 'high-risk' plaque that causes heart attacks and strokes. The approach provides detailed information about the size of plaque, inflammation, and potential risks, offering new insights into atherosclerosis.
Researchers from University of Pennsylvania and Philips team demonstrate improved image quality and shorter patient scan times with advanced molecular imaging technology. The study, released at SNM's 54th Annual Meeting, shows that TOF/PET imaging can achieve better quality images in less time, benefiting patients and doctors.
Researchers developed a 3D fusion technique combining CT angiography and nuclear imaging scans to improve the accuracy of diagnosing coronary artery disease. This technology significantly enhances diagnosis and could be used in the future with molecular imaging agents to detect and guide treatment.
Researchers unveiled the world's first simultaneous PET/MR images of the human brain, offering unprecedented imaging capabilities for neurological studies. The technology has the potential to revolutionize the assessment of Alzheimer's, Parkinson's, epilepsy, depression, and schizophrenia.
Beta-amyloid accumulation is linked to brain dysfunction even in normal elderly individuals, according to a study. Researchers used PIB PET scans to detect early pathological changes of Alzheimer's disease and demonstrated its potential for identifying those in need of treatment.
Adding radioimmunotherapy to chemotherapy increased complete response rates for patients with follicular lymphoma, a slow-growing type of non-Hodgkin's lymphoma. Over 90% of study patients responded completely to the treatment, with limited side effects.
Using metabolic imaging, UCLA researchers found that FLT-PET is a powerful predictor of treatment response and outcome in brain tumor patients. The study showed that FLT-PET imaging was predictive of patients' overall survival, with those who responded to drug treatment living three times as long as those who did not.
Early metabolic imaging with PET accurately identifies patients responding to chemotherapy for esophageal cancer, noting a remarkably favorable outcome for metabolic responders. This study supports the use of PET-response-guided treatment to tailor multimodality therapy based on tumor biology.
R. Edward Coleman received the award for his contributions to molecular imaging and nuclear medicine practice, particularly in advancing positron emission tomography (PET) for breast cancer, Alzheimer's, and brain tumors. His research has had a significant impact on medicine, and he is recognized as one of the best doctors in America.
Researchers are developing new electronics to accurately measure subatomic particles, potentially detecting cancer at an earlier stage. Improved Positron Emission Tomography (PET) technology could lead to better diagnoses and more accurate tumor detection.
Researchers found that FDG-PET imaging can identify patients who respond to chemotherapy, allowing for early termination of futile treatment. This improves patient care by providing an alternative approach, such as stopping chemotherapy or switching to a more adequate therapeutic option.
A study by University of Manchester researchers reveals that arthritis pain activates the brain's emotional and fear centers, processing emotions and aversive conditioning. The findings suggest a more intense emotional response to arthritic pain compared to experimental pain.
A study published in Arthritis & Rheumatism found that arthritis pain is processed in brain areas associated with emotions and fear. The medial pain system, including the cingulate cortex and amygdala, was activated during arthritic pain, suggesting a stronger emotional impact than experimental pain.
Researchers have identified promising new drug combinations that can improve survival rates among patients with severe heart disease. Studies show that using imaging technologies like PET-guided therapy can also help doctors make more accurate decisions about therapies for these high-risk patients.
A new study reports that zolpidem, an insomnia drug, temporarily improved brain function in a patient with akinetic mutism. The patient was able to communicate and perform basic functions after receiving the drug for insomnia. PET scans revealed increased brain activity in areas involved in motivation and cognitive processing.
A team led by Massachusetts General Hospital confirms that Pittsburgh Compound B binds to amyloid-beta protein in the human brain, a key step in Alzheimer's disease diagnosis. The findings support using PET imaging with PiB to track treatment results and emphasize the need for clinical symptom evaluation.
A new study at Memorial Sloan Kettering Cancer Center demonstrates the effectiveness of PET imaging in identifying clear cell renal carcinoma, a highly aggressive type of kidney cancer. The technique has a sensitivity of 94% and specificity of 100%, making it a valuable tool for determining whether surgery is needed.
International team develops standardized guidelines for assessing lymphoma treatment response, incorporating new imaging technologies. The revised guidelines aim to improve therapies and facilitate the development of new treatments.
Researchers used positron-emission tomography (PET scan) to diagnose a type of congenital hyperinsulinism, achieving an accuracy rate of 96% in locating the abnormal spot. The technology is highly effective in pinpointing focal lesions, guiding surgeons to curative organ-sparing surgery.
The International Harmonization Project has developed new guidelines for assessing lymphoma treatment, providing uniform criteria for clinical trials and interpreting response to treatment. The revised guidelines incorporate PET scans and immunohistochemistry, allowing for more accurate assessment of tumor viability.
The supplement examines the role of 18F-FDG PET/CT imaging in cancer diagnosis, treatment planning, and monitoring. It provides guidelines and algorithms for the use of PET/CT in evaluating and managing head and neck cancer and thyroid cancer.
Researchers have developed a promising radiotracer, FACBC, to improve prostate cancer diagnosis and staging. The tracer shows high accumulation in cancer cells and potential for overcoming traditional PET tracers' drawbacks.
Researchers developed a new imaging technique that detects abnormal brain protein deposits associated with Alzheimer's disease in mild cognitive impairment. The study found that the method was more effective in differentiating patients with Alzheimer's disease from normal subjects, and tracked disease progression over a two-year period.
A new imaging molecule, FDDNP, can detect and map plaques and tangles in the brains of people with Alzheimer's disease, enabling earlier diagnosis and potentially preventing progression. The compound binds to abnormal deposits on PET scans, correlating well with clinical diagnoses measured by memory tests.
Researchers found whole-body PET/CT scans accurate in diagnosing colorectal cancer stages, changing patient management in 9% of cases. This non-invasive method offers a single-stage approach, reducing burden on patients and clinicians compared to conventional imaging procedures.
A new study published in the Journal of Nuclear Medicine found that young smokers who quit smoking can normalize abnormal coronary artery function within a month. The PET imaging study examined the effects of smoking cessation on coronary endothelial dysfunction in healthy young male adults.
Advances in PET technology enable early disease detection and personalized medicine, potentially leading to annual screenings for common diseases. Doctors will use PET's molecular imaging ability to visualize precise molecular changes, informing treatment and prevention strategies.
A study of 79 patients diagnosed with obsessive-compulsive disorder (OCD) and compulsive hoarding syndrome found that serotonin reuptake inhibitor (SRI) medication, paroxetine, significantly improved symptoms. Compulsive hoarding is a psychiatric disorder characterized by failure to discard objects due to anxiety and excessive clutter.
Scientists create radioactively tagged molecules for positron emission tomography (PET) scans, providing insights into addiction and brain function. The radiotracers help monitor drug distribution and receptor activity in the brain, revealing key factors in addiction.
A recent study published in the Journal of Nuclear Medicine reveals that diabetes mellitus significantly slows nerve recovery after a heart transplant. This finding highlights the importance of understanding nervous system abnormalities to guide therapeutic efforts aimed at reducing cardiac risk for patients with diabetes.
Researchers at Cedars-Sinai Medical Center developed new objective criteria to enhance the reliability of PET scans in detecting breast cancer metastasis. The criteria use a standardized uptake value (SUV) threshold of 2.3, which was found to accurately diagnose lymph node involvement with 100% specificity and positive predictive value.
A new imaging technique using whole-body positron emission tomography (PET) scans can accurately predict whether breast cancer has spread to the lymph nodes in the armpit prior to surgery. The scans were found to be 72% accurate in identifying cancers with metastases, making them a valuable tool for healthcare providers.
Researchers found that nicotine receptors in the brain can become saturated with just a few puffs of a cigarette, leading to intense cravings and satiation. This study suggests that effective smoking cessation treatments need to be extremely potent to compete with nicotine's binding power.
At SNM's 53rd Annual Meeting, nearly 2,000 scientific and technologist abstracts were presented on various topics including cardiology, neurology, oncology, pediatrics, infectious disease, and more. The Society of Nuclear Medicine and Molecular Imaging also recognized individuals with named awards, lectures, and honors.
Stanford University researchers developed a 3D PET/CT imaging technique that provides a visual navigation of organs, allowing for better detection and characterization of cancer. The technology has potential for presurgical visualization, guiding biopsies and identifying tumor 'hot spots', enabling more precise diagnosis and treatment.
The publication of consensus recommendations for FDG PET usage is expected to reduce variability in clinical trials, leading to shorter trials and improved treatment outcomes. The guidelines provide a valuable reference for incorporating PET into clinical trials and promoting drug development.
Researchers at Johns Hopkins Medicine have developed a new PET radioligand, [11C]JHU75528, which allows for noninvasive visualization of central cannabinoid CB1 receptors in the human and animal brain. This breakthrough could lead to the development of new medications for treating obesity and drug dependence.
Researchers used FLT PET to monitor treatment response in DLBCL patients treated with R-CHOP chemotherapy. Treatment led to temporary increases in FLT uptake, indicating increased DNA synthesis and tumor cell proliferation. This suggests that FLT PET may be a sensitive tool for differentiating non-responding tumors.
Researchers found a link between increased serotonin receptors and body weight in overweight individuals. The discovery suggests that serotonin receptor manipulation could be a potential target for treating obesity.
Researchers have found that an ADHD medication 'harmonizes' with the body's dopamine system, improving attention and focus in individuals. The study, presented at a medical conference, provides direct evidence of the drug's beneficial effect, which was previously speculative.
Researchers at UCLA have developed a new method to detect Alzheimer's disease progression using FDDNP PET. The study shows that the worsening of memory and cognitive functions is correlated with increased 18F-FDDNP brain binding, providing valuable information for diagnosis and monitoring therapeutic interventions.
Researchers used FDG-PET imaging to diagnose osteomyelitis, achieving a 93% accuracy rate. The study's findings support the use of FDG PET as a diagnostic tool for chronic osteomyelitis.
Researchers found that FDG PET scans can accurately diagnose fevers of unknown origin in half of cases, eliminating the need for further tests. The study suggests that FDG PET offers an effective tool for early diagnosis, risk stratification, and treatment, reducing hospital stays.
Researchers at Massachusetts General Hospital developed PET/CT imaging to assess carotid plaque inflammation, identifying patients at high risk for heart attacks. This breakthrough may lead to more targeted interventions and improved patient outcomes.
Walter Wolf, distinguished professor of pharmaceutical sciences at USC, received the award for his groundbreaking work in pharmacokinetic imaging and radiopharmaceuticals. His research focuses on noninvasive studies of drug biodistribution and targeting using nuclear medicine imaging and magnetic resonance spectroscopy.
Gambhir, a renowned Stanford University scientist, is recognized for his extensive work in molecular imaging and basic science of using radioactive tracers. He has developed numerous methods for imaging gene/cell therapy and protein-protein interactions in living subjects.
A new time-of-flight PET scanner with LYSO detector crystals improves diagnostic accuracy and reduces variability in patient images. This technology enables more accurate detection of small lesions and better lesion characterization, leading to improved cancer diagnosis and treatment.
A new study finds that using PET and CT scans together during radiation therapy planning reduces errors due to patient motion, allowing for more accurate targeting of cancer cells. This approach may lead to more effective treatment with lower side effects.
The Society of Nuclear Medicine and Molecular Imaging (SNM) has released a landmark procedure guideline for tumor imaging with 18F-FDG PET/CT. The document provides recommendations for patient preparation, image acquisition, interpretation criteria, and quality control to ensure high-quality imaging results.
A Hopkins-led clinical study found that men's brains show a significantly higher dopamine release in response to amphetamines compared to women. This discovery may lead to more effective treatments for amphetamine abuse and brain diseases.
A study published in Annals of Surgery found that PET imaging was 88% accurate in identifying patients without disease after chemoradiation. This technology has the potential to change clinical practice by helping some patients avoid surgery.
Researchers used PET scans to evaluate response to chemoradiation in esophageal cancer patients. The study found that PET was 88% accurate at identifying patients without disease, potentially changing clinical practice and allowing some patients to avoid surgery.
A study in the Journal of Nuclear Medicine Technology found that physical activity, even minor exercises like turning a page or shoveling snow, can impact PET scan results and lead to false positives. To minimize this effect, patients should avoid excessive muscle activity 48 hours before scanning and inform their technologist.