Articles tagged with Positron Emission Tomography
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Joanna Fowler, a senior chemist at Brookhaven National Laboratory, will be awarded the National Medal of Science for her outstanding contributions to brain research and disease study. Her work using positron emission tomography (PET) has led to breakthroughs in understanding drug addiction and the human brain.
A new study published in The Journal of Nuclear Medicine shows that PET/CT scans with the imaging agent choline can detect recurring prostate cancer sooner than conventional imaging technologies. Researchers found a strong association between PET/CT detection and PSA levels, and suggest using specific criteria to reduce unnecessary scans.
Radiologists and medical physicists have implemented low-dose protocols and tracking systems to reduce cumulative ionizing radiation exposure. The Radiological Society of North America has launched initiatives to raise awareness of radiation risks and explore opportunities to improve patient safety through partnerships with the America...
A team of MIT chemists has created a new synthesis technique that allows for the easy addition of fluorine atoms to aromatic compounds, commonly used in drugs. This breakthrough could lead to more flexible and cost-effective drug design and development.
A new study found that positron emission tomography (PET) can accurately depict the extent of neuroblastoma in some patients, especially those with early-stage disease. FDG-PET imaging may also be useful in identifying malignant lesions not readily absorbable by MIBG.
Researchers found that low scores on a memory recall test and low glucose metabolism in brain regions can predict a 15-fold greater risk of developing Alzheimer's disease. The study used cognitive tests and brain scans to identify early warning signs of the debilitating disease.
Researchers have identified a combination of brain imaging, memory tests, and protein analysis that can accurately diagnose early-stage Alzheimer's disease. The study used data from the ADNI initiative and found that combining these methods resulted in classification accuracy rates of up to 95.7%.
A new study presents PET scan results that can accurately diagnose specific types of dementia, such as Alzheimer's disease, in the early stages. This can lead to targeted treatments and improved care outcomes for over 5 million newly diagnosed patients each year.
Researchers at SNM's Annual Meeting discovered that combining motion-frozen technology and high-definition PET enhances cardiac imaging, revealing defects invisible to physicians. The method provides exceptional image quality and significantly changes the diagnosis of patients with heart disease.
Researchers at SNM's 56th Annual Meeting propose a novel approach to reconstructing data that could enable the development of a hybrid PET-MR system. The new method uses MR images as a geometrical reference to estimate attenuation and improve accuracy.
Researchers have developed a new fully integrated PET/MRI system that can provide whole-body images of rats and small animals. The system offers significant improvements in imaging capabilities, enabling increased understanding of disease characteristics and physiological processes.
Researchers at SNM's 56th Annual Meeting present a prototype breast imaging system combining positron emission tomography (PET) and magnetic resonance imaging (MRI) technologies. The system aims to provide highly sensitive and specific breast cancer examinations while compensating for the shortcomings of individual PET or MRI systems.
Michael R. Kilbourn, a professor at the University of Michigan, received the prestigious Paul C. Aebersold Award for his contributions to molecular imaging and nuclear medicine. He has advanced research efforts in various areas, including positron emission tomography (PET) radiopharmaceuticals.
Researchers found that adults, particularly young women, have functional brown adipose tissue, which burns calories and generates heat. Three ounces of brown fat can burn hundreds of calories per day.
The Society of Nuclear Medicine and Molecular Imaging has published a comprehensive guide to PET scanning in cancer therapy, providing international guidelines and criteria for response assessment. The new supplement aims to improve tumor response assessment and treatment monitoring with FDG PET imaging.
The ADNI has completed a high-density genome-wide analysis of over 800 participants, providing a unique opportunity for researchers to explore genetic factors related to Alzheimer's disease. The data will be shared with scientists worldwide for further analysis and gene discovery.
Researchers used innovative brain-scan technology developed at UCLA to help diagnose brain aging, often before symptoms appear. The study combined PET scans with patient-specific information on Alzheimer's risk and found that older age correlated with higher concentrations of abnormal protein deposits in the brain.
A new technique for imaging the breast, positron emission mammography (PEM), has been found to be effective in detecting breast cancer without being affected by breast density or a woman's hormonal status. PEM has a higher sensitivity rate than standard mammography and breast MRI, with fewer false-positive results.
A nationwide study has confirmed the effectiveness of positron emission tomography (PET) in monitoring tumor activity and changing treatment plans for more than one out of three cancer patients. PET was found to be clinically significant, resulting in a change in treatment in 36% of cases.
A TGen-led team found a link between the brain protein KIBRA and reduced Alzheimer's disease risk in individuals with the T-allele gene. The study suggests that KIBRA may play a role in Alzheimer's disease, providing promising new targets for treatments.
A recent study found that positron emission tomography (PET) scans led to changes in treatment plans for more than half of patients with suspected recurrent colorectal cancer. The study, conducted at four sites in Australia, involved 191 patients and showed that PET scans identified additional disease sites in 48% of patients, allowing...
Researchers found that serotonin transporter binding potential values were higher in fall and winter, suggesting a link between lower serotonin levels and seasonal mood changes. The study suggests that variations in brain serotonin levels may explain why people feel happier on sunny days and more sluggish during the dark winter season.
Recent advancements in cardiac imaging have led to the detection of impairments in cellular processes that precede changes in morphology and function. These early stages can be identified through various imaging techniques such as PET, nuclear imaging, MRI, ultrasound, and optical imaging.
A new PET study reveals a direct correlation between hereditary personality traits, particularly reward dependency, and brain chemistry. Individuals with high reward dependence have higher opiate receptor binding in the ventral striatum, associated with increased cravings and addictive behavior.
A type of PET scanning may be useful in non-invasive assessment of brain plaque formation. Six patients with beta-amyloid plaques displayed a higher uptake of the marker [11C]PiB in certain brain areas compared to those without such accumulations.
A small sample of adults with mild age-related memory loss showed increased brain metabolism and normalized brain function after taking Aricept for 18 months. The study suggests treating early symptoms of memory loss may protect the brain and help with mild age-related cognitive decline.
A study published in Biological Psychiatry found that deep brain stimulation (DBS) in the subcallosal cingulate region significantly improves symptoms of treatment-resistant depression. The procedure showed continued and sustained benefits over time, with no long-term side effects reported.
The NIH is providing $33.3 million for 20 High-End Instrumentation grants, supporting the purchase of advanced research equipment costing over $750,000. These grants aim to enable new discoveries and treatments in disease areas such as heart disease, cancer, and Alzheimer's.
Using an engineered virus, UCLA researchers locate prostate cancer cells in the pelvic lymph nodes, where it spreads first before invading other organs. The discovery may lead to more effective diagnostic and therapeutic approaches for advanced prostate cancer.
Researchers developed a promising new technique to track genetically engineered cells using antibody fragments as reporter genes, which could advance disease treatment. The technique offers several advantages over existing methods, including improved specificity and accuracy.
Two images, one showing neuroendocrine cancer relapse and the other a foot infection, demonstrate molecular imaging's ability to provide precise snapshots of disease anatomy. Imaging techniques are increasingly being used in combination to improve treatment planning and patient outcomes.
Researchers used PET scans to analyze 38 patients with non-Hodgkin's lymphoma treated with 90 ibritumomab tiuxetan. The study found that 89% of patients were in complete or partial remission after treatment, with a higher response rate for patients with limited cancer progression.
Researchers used PET imaging to detect structural and functional alterations in the circulatory system of asymptomatic diabetic patients. The study found that PET revealed coronary vascular dysfunction as a precursor to coronary artery disease, which may precede structural changes in the arterial wall.
Scientists used Exploratory Investigational New Drug (ExpIND) to evaluate four 18F-labeled imaging agents in patients with Alzheimer's disease, identifying the best detector of amyloid plaque deposits. The study suggested that ExpIND could speed up the development of new radiopharmaceuticals while ensuring patient safety.
The first semiconductor-based PET scanner demonstrates improved spatial resolution and reduced noise, enabling better characterization of diseases such as partial epilepsy and nasopharyngeal cancer. This technology holds promise for advancing early-stage diagnoses and assessing patient responses to therapies.
The new scanner enables physicians to determine stages of breast cancer in patients already diagnosed, rather than as a mammography screening tool. It also helps plan breast cancer surgeries and detect early whether drug treatments are effective.
A meta-analysis found that PET imaging failed to identify 50% of occult lesions in clinically node-negative patients, while incorrectly identifying normal tissue as cancerous 13% of the time. The study suggests that FDG-PET may not improve diagnostic accuracy for early head and neck cancer
Researchers at Michigan State University have developed a method to create specific rare isotopes for scientific research, opening doors to new technologies. This capability promises to advance fields like biomedicine, international security, and nuclear energy.
Researchers used PET and SPECT imaging to monitor the effectiveness of a new therapy, which successfully preserved healthy heart tissue and corrected blood flow imbalance. Nearly 50% of repaired artery segments showed normalization of glucose metabolism and coronary blood flow.
A team of Stanford University School of Medicine researchers has developed a new type of imaging system using Raman spectroscopy to illuminate tumors in living subjects. The technique allows for the detection of multiple molecular targets simultaneously, enabling finer biochemical details and more precise imaging.
Researchers confirm that Pittsburgh Compound-B binds to beta-amyloid deposits found in Alzheimer's brains, enabling definitive diagnosis. The finding aids in early detection and treatment of the disease.
Recent data from the National Oncologic PET Registry (NOPR) shows that PET scans can dramatically change treatment plans for cancer patients, with a 36.5% change in treatment or no-treatment decisions reported.
The University of Pittsburgh Center for Vaccine Research has received a $11.4 million grant to study tuberculosis using new imaging technologies. The goal is to develop more effective treatments that can be tailored to individual patients, potentially improving survival rates and curtailing the global TB epidemic.
Researchers at the University of Southern California found that combined positron emission tomography (PET) and computed tomography (CT) imaging yields greater accuracy when evaluating response to radiation therapy. This method helps identify complete responders and reduces the need for unnecessary chemotherapy treatments.
The combined scanner uses a new technology to eliminate interference between MRI and PET systems, enabling simultaneous acquisition of structural and functional information. This innovation allows researchers to correlate tumor structure with functional information, providing deeper insights into cancer research.
Researchers used PET imaging with fluorodeoxyglucose (FDG) to classify different types of dementia, achieving over 94% accuracy. The study suggests that early diagnosis using FDG-PET may improve prognosis for patients with mild cognitive impairment and other forms of dementia.
Researchers demonstrate increased endorphin release in athletes' brains during long-distance running, linked to reduced pain perception and improved mood. The study provides direct evidence for the 'endorphin hypothesis', a theory that had been disputed until now.
The American Association of Physicists in Medicine celebrates its 50th anniversary, highlighting key contributions of medical physicists to medicine. Medical physicists have developed technologies such as MRI, CT scanning, and PET scanning, which have transformed imaging and cancer treatment.
Researchers found that early brain activity is shaped by language experience and plays a crucial role in speech perception. The study reveals that melody of speech engages multiple brain areas, including both hemispheres, and interacts with general sensory-motor processes.
A multi-institutional study found PET more reliable than CT in characterizing lung nodules as malignant. PET's superior specificity led to correctly classifying 58% of benign nodules misclassified on CT.
A UCLA study found PET scanning more sensitive and accurate than conventional imaging methods in detecting treatment response in sarcoma patients. Standard size-based evaluation methods only identified 20% of responders, while PET accurately picked up all responders.
The PEM/PET system can spot tumors half the size of standard imaging systems, and complete an image and biopsy in a similar time frame. It features high-resolution PET images of the breast, guiding needle biopsies with a robot arm.
Researchers discovered significant changes in brain activity with intensive cognitive-behavioral therapy, leading to improved symptoms and reduced anxiety. The study suggests that this type of therapy may be more effective than previously thought, with potential implications for treatment.
A recent study published in the Journal of Nuclear Medicine found that PET/CT imaging significantly outperforms conventional imaging for detecting malignant tumors in children. The imaging modality provides additional information about cancer in children, potentially sparing them from overtreatment.
Researchers used PET imaging and bioluminescence to track stem cell behavior in small animal models, determining their fate and potential applications in treating heart diseases, brain disorders, and cancer. The unique combination of these imaging techniques offers a reliable method for labeling stem cells.
A systematic review of recent studies suggests PET imaging can accurately diagnose and stage lung cancer, even in early stages. The imaging modality is found to be more accurate than CT imaging for treatment decisions in non–small-cell lung cancer patients.
PET imaging enhances lung cancer staging by providing complementary information on biochemical processes, accurately differentiating between benign and malignant tumors as small as 1 centimeter. The study also found PET to be more effective for mediastinal staging in non-small cell lung cancer.
Post-treatment PET scans can accurately detect cervical cancer tumor response and predict long-term survival. The scans help identify patients whose tumors have not responded to therapy, allowing for alternative treatment options.
A comprehensive review by the UK National Health Service found that PET scans can help diagnose and treat certain types of cancer more accurately than other imaging technologies. However, it is unclear whether these advances lead to improved patient outcomes and survival rates.
A PET scan significantly improves the accuracy of diagnosing Alzheimer's disease and frontotemporal dementia (FTD) by measuring brain sugar uptake. The study found that FDG-PET scans correctly diagnosed FTD and Alzheimer's in almost 90% of cases, increasing accuracy by 14%.