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Exposure therapy may help prevent post-traumatic stress disorder

A randomized controlled trial found that exposure therapy was more effective than cognitive restructuring in preventing PTSD in individuals with acute stress disorder. Exposure therapy reduced distress ratings and promoted full remission, suggesting its potential as an early intervention for high-risk patients.

SourceJAMA Network·JournalArchives of General Psychiatry·DateJun 2, 2008

Does stress damage the brain?

A study found reduced gray matter density in the pregenual anterior cingulate cortex of combat-exposed veterans with PTSD, but not their identical twins. The researchers suggest that stress exposure may cause this damage, leading to emotional consequences.

SourceElsevier·JournalBiological Psychiatry·DateMar 18, 2008

Asthma link to post-traumatic stress disorder, says Mailman School of Public Health study

A study by Columbia University's Mailman School of Public Health found a significant link between asthma and post-traumatic stress disorder (PTSD) among adults. The research suggested that the association is not primarily due to genetic influences, but rather may be related to immune system functioning or common risk factors.

SourceColumbia University's Mailman School of Public Health·JournalAmerican Journal of Respiratory and Critical Care Medicine·DateNov 20, 2007

Mice offer clues to the roots of human resilience

A new mouse study found that mice who are more susceptible to social defeat show increased levels of a growth factor known as BDNF in their brains' reward circuits, which promotes plasticity and learning. Resilient mice, on the other hand, did not exhibit this chemical rise, suggesting a potential link between BDNF and human resilience.

SourceCell Press·JournalCell·DateOct 18, 2007

How emotionally charged events leave their mark on memory

Researchers have discovered a mechanism that strengthens memory connections in response to emotional stress, which may underlie why traumatic events can be more vividly remembered than everyday ones. The study found that the stress hormone norepinephrine enhances learning and memory by increasing GluR1 receptors.

SourceCell Press·JournalCell·DateOct 4, 2007

1 in 8 World Trade Center rescue and recovery workers developed post-traumatic stress disorder

New findings from the WTC health registry show that post-traumatic stress disorder affected 12.4% of rescue and recovery workers, with volunteer workers having the highest rate. The prevalence of PTSD varied significantly by occupation, with workers from non-emergency occupations such as construction suffering particularly high rates.

SourceNew York City Health Department·JournalAmerican Journal of Psychiatry·DateAug 29, 2007

A brain chemical that battles despair

Studies reveal a gene-regulating protein that triggers coping mechanisms in mice exposed to inescapable stress, leading to reduced behavioral despair. The discovery provides an animal model for exploring how antidepressants work on the brain circuitry involved in stress response.

SourceCell Press·JournalNeuron·DateJul 18, 2007

PTSD may increase heart disease risk in older men

A prospective study found that higher levels of PTSD symptoms are associated with an increased risk of non-fatal and fatal coronary heart disease in older male veterans. The study analyzed data from 1,946 men enrolled in the Veterans Affairs Normative Aging Study.

SourceJAMA Network·JournalArchives of General Psychiatry·DateJan 1, 2007