Researchers in The Netherlands and Belgium developed a new technique that uses genetically engineered rhTSH to stimulate thyroid cancer cells to absorb radioactive iodine, avoiding hypothyroidism and increasing safety. This approach may allow higher doses of radioiodine to be used when needed, improving treatment efficacy.
SourceSociety of Nuclear Medicine and Molecular Imaging·JournalJournal of Nuclear Medicine·DateSep 17, 2004
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A recent study published in Radiation Research has established a dose-response relationship between radiation dose from Chernobyl and thyroid cancer. Researchers found that the incidence of thyroid cancer was 45 times greater among those who received the highest radiation dose compared to those in the lowest-dose group.
SourceFred Hutchinson Cancer Center·JournalRadiation Research·DateSep 1, 2004
A new study found that most phase I studies of targeted, non-cytotoxic anticancer agents used traditional toxicity endpoints to determine the recommended dose, while non-traditional endpoints were rarely incorporated. Researchers also identified a potential mechanism for acrylamide's mutagenicity and discovered genetic polymorphisms as...
SourceJournal of the National Cancer Institute·JournalJNCI Journal of the National Cancer Institute·DateJul 6, 2004
A new treatment using genetically engineered thyrotropin alfa eliminates the need to withhold thyroid hormone medication after thyroidectomy, reducing symptoms of hypothyroidism. The study shows that patients can be treated effectively without experiencing unpleasant side effects.
A study examining health care benefits and disadvantages when physicians treat themselves found that even doctors who disapprove of self-doctoring may do so due to lack of thought. Benefits include convenience and control, but also risks such as delayed care and ignoring medical instincts.
A new study published in The Journal of Nuclear Medicine found that taking patients off thyroid medication for only two weeks prior to a scan produces the desired changes in nearly 90% of patients. This simplified approach reduces the need for six-week follow-up scans, making it easier and quicker for patients.
SourceWashU Medicine·JournalJournal of Nuclear Medicine·DateMar 30, 2004
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The study found that rhTSH reduced the mean effective half-life of radioiodine by 26% in patients who received it before therapy. This reduction allowed patients to clear 131I more rapidly, resulting in lower radiation levels in their blood and tissues.
SourceSociety of Nuclear Medicine and Molecular Imaging·JournalJournal of Nuclear Medicine·DateJul 7, 2003
Researchers at Johns Hopkins Medicine discovered a BRAF gene mutation in 68% of papillary thyroid cancers, which can be challenging to distinguish from benign conditions. This mutation causes continuous cell growth and division, leading to cancer.
SourceJohns Hopkins Medicine·JournalJNCI Journal of the National Cancer Institute·DateApr 15, 2003
A study published in the Journal of the National Cancer Institute found that only 40% of patients with superficial bladder cancer had regular follow-up examinations, despite recommended guidelines. Patient characteristics such as age, ethnicity, and socioeconomic status were independently associated with low-intensity surveillance.
SourceJournal of the National Cancer Institute·JournalJNCI Journal of the National Cancer Institute·DateApr 15, 2003
Recent cancer patient data reveals higher-than-expected five-year to twenty-year relative survival rates across various types of cancer. Period analysis shows more optimistic estimates compared to traditional cohort-based methods.
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Chernobyl exposure linked to increased thyroid cancer in children, while HRT use may increase breast-cancer risk with long-term use. The Lancet Oncology reviews these findings and highlights the need for prospective trials. Increasing age is associated with rising cancer incidence, making geriatric oncology crucial.
SourceThe Lancet_DELETED·JournalThe Lancet Oncology·DateMay 1, 2002
The Chernobyl nuclear disaster has led to a significant increase in thyroid cancer cases, particularly among children and young adults who were exposed to fall-out. The risk of thyroid cancer continues to rise, with the highest rates seen 15-19 years after exposure.
SourceECCO-the European CanCer Organisation·DateOct 23, 2001
A study published in The Journal of Nuclear Medicine found that FDG PET detected recurrent thyroid cancer 50% more often than conventional imaging, leading to changes in clinical management for almost 80% of patients. The PET scan identified additional tumor sites and distant metastases, improving patient outcomes.
SourceSociety of Nuclear Medicine and Molecular Imaging·JournalJournal of Nuclear Medicine·DateOct 3, 2001
A recent study published in Thyroid journal found paclitaxel to have significant clinical activity against ATC, with 53% of patients showing improved survival time. The drug was infused continuously over 96 hours every three weeks for one to six treatments.
SourceUniversity of Kentucky Medical Center·JournalThyroid·DateSep 5, 2000
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Research finds patients treated for Hodgkin's disease as children are nine times more likely to develop a second cancer, with specific types of cancer at higher risk. The study suggests regular screening is necessary to monitor patients' lifetime health.
A new study at Johns Hopkins suggests a safe and effective way to detect left-over thyroid cells using PCR technology. The test relies on detecting genes for thyroglobulin in patients' blood, allowing them to stay on their thyroid hormone medication while reducing the risk of false results.
SourceJohns Hopkins Medicine·JournalThe Journal of Clinical Endocrinology & Metabolism·DateDec 1, 1998
A study by Johns Hopkins researchers found that surgical experience is a crucial factor in achieving better clinical outcomes for patients undergoing thyroidectomy. The results showed that surgeons performing the most thyroid operations had lower complication rates, shorter hospital stays, and lower average hospital charges. This study...
SourceJohns Hopkins Medicine·JournalAnnals of Surgery·DateOct 7, 1998
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