Articles tagged with Insulin Sensitivity
Research reveals that intermittent hypoxia associated with sleep apnea can cause distinct drops in insulin sensitivity in mice. This finding suggests that sleep apnea may increase the risk of developing metabolic disorders such as type 2 diabetes.
A new study found that just one night of short sleep duration can cause significant changes in metabolic regulation, leading to impaired glucose tolerance and insulin resistance in healthy individuals. Researchers used the hyperinsulinemic euglycemic clamp method to measure insulin sensitivity before and after a night of either normal ...
A study of 5,115 young adults found that increased prices for unhealthy foods like soda and pizza led to decreased calorie consumption and weight loss. The researchers estimate that an 18% tax on these foods could result in a decline of roughly 56 calories per person per day.
A study published in the Journal of Applied Physiology found that the type of food eaten after exercise can significantly impact metabolic health. Eating low-carbohydrate meals after exercise enhanced insulin sensitivity more than eating balanced or low-calorie meals. The study suggests that people can still reap important health benef...
Researchers at LSU Health Sciences Center found that children as young as 7 can exhibit early signs of diabetes, including poor insulin sensitivity and high insulin resistance. The study identified fat oxidation, blood pressure, and lipids as key predictors of insulin sensitivity in this age group.
A study published in The Lancet found that metabolic changes, including increased fasting glucose levels and decreased insulin sensitivity, occur several years before the onset of type 2 diabetes. By identifying these changes, it may be possible to delay or even prevent diabetes diagnosis.
A recent study has found that the Humanin peptide protects against neuronal cell death and regulates insulin metabolism, significantly improving glucose levels in diabetic rats. The discovery provides new insight into the role of the brain in glucose metabolism and suggests a potential therapeutic approach to diabetes.
A study found that consuming fructose-sweetened beverages increased intraabdominal fat and decreased insulin sensitivity, while glucose-sweetened beverages had no significant effects. This suggests that fructose may be more detrimental to health than glucose.
Researchers at Joslin Diabetes Center have discovered that subcutaneous fat, typically found in the hips and thighs, can lower insulin levels and enhance insulin sensitivity. This discovery offers a new avenue for finding substances produced by subcutaneous fat that may improve glucose metabolism.
Research suggests that insulin inhibits resistin expression and secretion in adipocytes, but resistin induces cellular insulin resistance in hepatocytes and myoblasts. Serum resistin levels correlate negatively with insulin sensitivity in diet-induced obesity rats.
A new study found that overweight type 2 diabetes patients who consumed moderate amounts of sugar from carrot cake experienced no adverse changes in blood glucose levels. The study, conducted over 24 days, showed improved insulin sensitivity and balanced energy intake.
A recent study found that suppressing slow-wave sleep in healthy young adults significantly decreases their ability to regulate blood-sugar levels. After only three nights of selective slow-wave sleep suppression, subjects became less sensitive to insulin, resulting in reduced tolerance to glucose and increased risk for type 2 diabetes.
Researchers found that low doses of resveratrol improve insulin sensitivity in mice, reducing the risk of type 2 diabetes. The study suggests that foods enriched with resveratrol or supplemented with the chemical may be a better option for improving insulin sensitivity.
A study by the University of Copenhagen found that soccer players experienced greater improvements in fitness ratings and muscle mass compared to joggers. The researchers attribute this to the shifts between walking, running, and sprinting in soccer, which engages multiple muscle fibers.
A Yale-developed weight management program cut diabetes risk and improved BMI in overweight children by increasing insulin sensitivity and reducing body fat. The Bright Bodies program, which combined nutrition education, behavior modification, and exercise, was more effective than traditional clinic-based counseling.
A study at the University of Illinois Chicago found that pioglitazone significantly slowed the thickening of carotid artery walls, reducing the risk of heart attack. The medication was shown to be effective regardless of age, sex, or diabetes duration.
miR-278 plays a crucial role in regulating insulin sensitivity in flies, with reduced insulin sensitivity and elevated blood glucose levels observed in flies lacking this microRNA. The study highlights the importance of microRNAs in metabolic regulation.
The study found that SOCS-7-deficient mice have increased IRS protein levels and prolonged IRS activation, leading to enhanced insulin action and glucose homeostasis. The researchers also observed increased growth of pancreatic islets with elevated fasting insulin levels and hypoglycemia.
A two-week course of fenofibrate treatment has significantly improved whole body glucose uptake and insulin sensitivity in pediatric burn victims, reducing morbidity outcomes and healing rates. The study showed that treating insulin resistance directly can aid recovery from general trauma, illness, or surgery.
Research by Martin Muurling found that mice on low-fat diets were more sensitive to insulin, suggesting a low-fat diet may be a more effective remedy for diabetes. The study also showed that consuming fish oil had no positive effects on reduced insulin sensitivity.
A study of Latino children found that nearly three in ten have impaired glucose tolerance, a precursor to type 2 diabetes, while obesity rates are twice those of non-Latino peers. Insulin resistance and metabolic syndrome increase the risk of chronic diseases.
Recent studies show that overweight Hispanic youth are at an increased risk for developing type 2 diabetes and cardiovascular disease. Insulin resistance directly contributes to the development of metabolic syndrome, particularly in those with a family history of diabetes.
A Mayo Clinic study found that middle-aged and older adults who engage in regular aerobic exercise can maintain increased insulin sensitivity for up to four days after their last workout. However, this effect is not seen in those over 40, highlighting the importance of frequent exercise for preventing or treating Type 2 diabetes.
A study of 289 teenagers found that cardiovascular fitness and lower body fat are independently associated with greater insulin sensitivity. Improving fitness or reducing body fat could protect high-risk children from developing insulin resistance, a precursor to diabetes.
A University of Otago study found that intensive exercise and specific dietary changes can improve insulin sensitivity by up to 20% in otherwise-healthy individuals. The research, which included 79 participants aged 35-60, also showed a significant improvement in insulin action among Māori participants.
A study by Raben et al. found that postobese women have different metabolic profiles than never obese women, with greater insulin sensitivity and more efficient triacylglycerol storage. This suggests that weight loss may not entirely eliminate the risks associated with obesity.
Recent advances in diabetes treatment have improved blood sugar control, allowing patients to dodge complications until late life. New drug therapies, including metformin and insulin analogs, have enhanced treatment possibilities.
Researchers found that participants with high insulin resistance were more likely to develop high blood pressure, highlighting a potential new treatment target. The study also suggests that reducing insulin resistance may help prevent hypertension and cardiovascular disease.
A team of Type 1 diabetic athletes, including University of North Carolina M.D.-Ph.D. candidate Jeremy Ackerman, will climb Cerro Aconcagua in Argentina to raise awareness about diabetes and conduct scientific research on the effects of altitude on diabetics.
Researchers found that rosiglitazone treatment improved glycaemic control and reduced risk factors for coronary heart disease in patients with type 2 diabetes. The medication also showed promise in reducing protein excretion and triglycerides, while improving lipid profiles.
A recent study found that low-level inflammation in adults is connected to measures of insulin metabolism. The loss of sensitivity to insulin contributes to diabetes, which in turn is a major cause of heart disease. High levels of C-reactive protein indicate low-level inflammatory status and are associated with increased risk of cardio...
A team of Canadian scientists identified a potentially useful target for drugs to treat type II diabetes and obesity by genetically engineering mice lacking a specific enzyme. The results showed that these mice resisted weight gain and insulin resistance on a high-calorie diet, suggesting a possible approach for treating the disease.
A recent study suggests that moderate drinking may protect against coronary heart disease by improving insulin sensitivity. Analysis of a large Italian database found that the prevalence of Syndrome X, a condition characterized by abnormal levels of triglycerides, HDL cholesterol, blood pressure, and glucose, was significantly higher a...