Articles tagged with Miscarriage
Research found that women who experienced recurrent miscarriage were five times more likely to have a heart attack in later life. Those who had stillbirths were also at increased risk of cardiovascular disease.
A study by Ashley Moffett's team found that specific interactions between maternal cells and fetal trophoblasts play a key role in determining successful pregnancy. The presence of certain maternal immune system genes provides protection against recurrent miscarriage, preeclampsia, and fetal growth restriction.
Research at the European Society of Human Reproduction and Embryology found that overweight women undergoing IVF or ICSI are twice as likely to miscarry. Women with normal weight have a significantly lower miscarriage rate, highlighting the importance of pre-conception counseling for those using ART.
A new study published in CMAJ found a significant association between antidepressant use during pregnancy and an increased risk of miscarriage. The study, which analyzed data from over 5,000 women, found that selective serotonin reuptake inhibitors (SSRIs) were associated with a higher risk of miscarriage, particularly at higher doses.
Recent studies on anticoagulants suggest that aspirin and heparin may not be effective in preventing unexplained, recurrent miscarriages. In contrast, a new study shows that dabigatran etexilate is as safe and effective as warfarin for treating venous thromboembolism.
A study of over 64,000 pregnant women found that larger hospital units with more experience had lower miscarriage rates after amniocentesis and chorionic villus sampling. The research suggests that the number of procedures carried out by a department affects miscarriage rates.
A comprehensive review of 75 studies found that complications in early pregnancy can increase the risk of preterm or very preterm delivery, placenta praevia, and congenital malformations. Identifying these risks allows clinicians to provide targeted monitoring and care for high-risk patients.
Researchers identified Gpx5 as a protective protein for immature sperm in the epididymis, reducing oxidative stress and associated with improved fertility outcomes. In contrast, males lacking Gpx5 showed increased miscarriage rates and fetal developmental defects.
A UNICEF-funded study found that sexual violence against female children in Africa is linked to a higher risk of lifetime STD contraction, pregnancy complications, miscarriage, and depression. The study suggests that prevention strategies should focus on men who perpetrate sexual violence against girls.
Researchers at the University of Bonn discover brown dwarfs must be treated as a separate class due to their unique mass distribution and 'mating behaviour'. This reclassification challenges current understanding of stellar formation and population dynamics.
A recent study by Dr. Stéphanie Belloc found that men over 35 have a negative impact on pregnancy rates and increase miscarriage risks in women undergoing intrauterine inseminations (IUIs). This marks the first time a strong paternal effect has been shown, contradicting previous assumptions about the role of the father in fertility.
A new study found that men with lower folate intake have higher rates of chromosomal abnormalities in their sperm, which could affect reproductive health and birth outcomes. Higher folate intake was associated with lower rates of these abnormalities.
A medical team from the University of Leicester has developed a predictor for pregnant women who may have miscarriages, using levels of anandamide in whole blood. The study found that women with higher levels of anandamide were more likely to miscarry, while those with lower levels were more likely to have a live birth.
A Kaiser Permanente study found that high doses of caffeine daily during pregnancy increase the risk of miscarriage, particularly among women consuming coffee, tea, and hot chocolate. Women who consumed over 200mg of caffeine per day had twice the miscarriage risk compared to those with no caffeine intake.
Women who are underweight before pregnancy are 72% more likely to miscarry in the first three months. However, taking vitamin supplements, eating fresh fruit and vegetables daily, or consuming chocolate can significantly reduce their risk.
Six Bulgarian nurses and a Palestinian doctor were wrongly accused of deliberately infecting over 400 children with HIV in Libya since 1999. The Lancet calls for their immediate release due to lack of legal basis.
Researchers found that both amniocentesis and chorionic villus sampling (CVS) carry a low risk of miscarriage. While CVS was initially believed to have a higher rate of miscarriage, the study revealed that this risk decreased over time.
A large study found that increasing paternal age is significantly associated with increased rates of spontaneous abortion. Women with partners aged 35 or older had nearly three times as many miscarriages as compared to women conceiving with men younger than 25 years of age.
A new method of testing eggs for abnormalities could solve problems of embryo freezing, reducing the risk of miscarriages in women undergoing IVF. The technique analyzes the first polar body to identify viable eggs, resulting in lower early miscarriage rates and improved implantation potential.
Women who had an abortion experienced more mental distress in the long term compared to those who had a miscarriage. They also reported higher levels of anxiety and felt guilty or ashamed about their decision.
A study found that prednisolone significantly reduces uNK cell numbers in the endometrium, potentially offering new hope for women with recurrent miscarriages. The treatment's effectiveness is still unclear, as it was only tested for three weeks and longer-term results are needed.
A leading researcher is presenting data on a new infertility drug that has shown promising results in reducing miscarriage rates in mice. The drug, PV903, contains an active ingredient found in semen and aims to instruct the mother's immune system to tolerate the fetus.
Researchers found that a critical protein called Serum Response Factor (SRF) is essential for the development of heart cells, and its absence can lead to improper heart function. The study provides new insights into how genetic mutations may disrupt heart function and potentially cause adult cardiovascular disease.
A study published in Nature Medicine reveals that heparin works by blocking the activation of the complement pathway, a series of inflammatory proteins involved in pregnancy loss and placental injury. This new mechanism suggests potential targeted therapy for patients with antiphospholipid syndrome.
A new study has found that high levels of thyroid hormone are linked to an increased risk of miscarriage in women who are resistant to normal levels. The research, conducted on a family with a rare genetic disorder, revealed a significant increase in miscarriage rates among affected mothers compared to unaffected relatives.
Early study results show that women with small uterine fibroids may be at increased risk of miscarriage, with smaller fibroids more associated with pregnancy loss. The research aims to investigate the influence of fibroids on pregnancy outcomes and will enroll an additional 3,300 ethnically diverse women.
A study found that women who experienced miscarriage had lower concentrations of macrophage inhibitory cytokine-1 compared to those who delivered normally. Low MIC1 levels often preceded miscarriage, suggesting its potential as a predictor and therapeutic target for pregnancy loss prevention.
The study found that 40% of miscarriages can be attributed to embryonic congestive heart failure, which can be identified using Doppler technology. The condition is characterized by increased free amniotic fluid and depressed myocardial contractility.
A study found that 32% of women reported increased interpersonal distance and 39% experienced more distance in their sexual relationships one year post-miscarriage. Women who felt distant saw their miscarriage as a significant loss, leading to increased emotional disturbance and decreased love and communication with their partners.
A study by Dr Ole Christiansen found that women who gave birth to a boy first were at higher risk for subsequent miscarriages and may not be able to carry a child to full term without treatment. The researcher believes that the immune system's reaction to male foetuses is the explanation for these findings.
A study found that women with bacterial vaginosis or abnormal vaginal flora had a higher risk of late miscarriage and spontaneous preterm delivery. Treating these conditions with antibiotics may reduce this risk, with the number of women needed to be treated calculated at around ten.
A recent study by W. Allen Hogge, M.D., found that nearly 56% of miscarriages are caused by chromosomal abnormalities, with higher rates among women over 35. The study recommends regular karyotyping tests after the second loss and more advanced testing only when no genetic abnormality is found.
Researchers found that chromosomal abnormalities in embryos were a common cause of unexplained recurrent miscarriages and implantation failure. By using Preimplantation Genetic Diagnosis (PGD), normal embryos can be selected for transfer, leading to similar pregnancy rates as fertile women.
Researchers found that showering increased THM levels in blood by a factor of four, suggesting the compounds are getting into the bloodstream through water use. The study investigated THM concentrations in women's blood before and after showering, revealing correlations with local tap water quality.
The Antiphospholipid Syndrome Collaborative Registry aims to enroll 2,000 patients over five years to better understand the disease, its causes, and treatment options. The registry will facilitate research, diagnosis, and development of diagnostic tests and treatments for antiphospholipid syndrome.
A study suggests that metformin, an oral diabetes drug, reduces the risk of miscarriage in women with Polycystic Ovary Syndrome (PCOS). Researchers found that 8.8% of pregnancies treated with metformin ended in miscarriage, compared to 41.9% in those not receiving the medication.
A prospective study found that women with Factor V Leiden mutations had low live birth rates compared to those without the mutation. The research suggests that targeted anti-blood clotting treatment may be beneficial for these women, and screening is recommended.
A large-scale study found no association between folic acid supplement use and increased risk of miscarriage. The researchers assessed 23,806 women who had taken part in a folic-acid campaign before becoming pregnant for the first time.
Researchers found a connection between a specific gene variation and recurrent miscarriages, with women carrying the variation having a 1.6-fold increased risk of pregnancy loss. The study suggests that nitric oxide plays a mediating role in early pregnancy and may be linked to impaired placental function.
A study by Israeli fertility experts found that a quarter of women and two husbands had abnormal chromosomes, leading to repeated embryo implantation failure. The researchers are calling for an international registry to be established to record chromosomal aberrations in infertility patients.
A research team has found that the immune system protein Crry is essential for fetomaternal tolerance in mice, preventing destruction of the developing fetus. Without this protein, complement components activate, leading to embryonic death and miscarriage.
A study by researchers at the National Institute of Child Health and Human Development found that consuming high amounts of caffeine doubles the risk of miscarriage. Moderate caffeine consumption was not linked to an increased risk, however.
A large-scale study by the University of Chicago found that immunotherapy, a treatment aimed at preventing recurrent miscarriage, is not effective. Women who received this treatment had more and later miscarriages compared to those receiving a placebo.