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NTU Singapore scientists discover why wavy wounds heal faster than straight wounds

Researchers at Nanyang Technological University found that cells near wavy shaped wounds moved in a swirling manner, while those near straight wounds moved in straight lines. This discovery reveals that the swirling motion is crucial for gap-bridging and accelerates wound healing in wavy wounds.

SourceNanyang Technological University·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateMay 14, 2023

Endovascular treatment more likely to avoid amputation or death for limb-threatening artery disease

A randomized controlled trial shows that a best endovascular treatment first revascularisation strategy is more effective in preventing major amputation and death than a vein bypass first strategy for patients with chronic limb-threatening ischaemia. The study, BASIL-2, recruited 345 patients from the UK, Sweden, and Denmark and found ...

SourceUniversity of Birmingham·JournalThe Lancet·TypeRandomized controlled/clinical trial·DateMay 2, 2023

Obesity associated with increased risk of complications after surgery

New research published in the journal SURGERY found that obesity is associated with increased risk of complications following surgery, including infection, blood clots, and kidney complications. Patients with overweight or obesity had higher risk-adjusted odds of developing these post-operative outcomes compared to those of normal weight.

SourceUniversity of Colorado Anschutz Medical Campus·JournalSurgery·TypeData/statistical analysis·DateMay 1, 2023

Research shows that lymph node sampling during kidney tumor surgery is safe

Researchers analyzed outcomes for 144 Colorado patients who had lymph node sampling at the time of surgery for kidney tumors between 2005 and 2019. They found no statistically significant difference in clinically significant complications between patients who underwent more extensive lymph node sampling than those who didn’t.

SourceUniversity of Colorado Anschutz Medical Campus·JournalThe Journal of Urology·TypeData/statistical analysis·DateMay 1, 2023

Improving geriatric surgical quality is feasible for a wide range of hospitals

A national pilot program evaluated the implementation of geriatric surgery standards in eight hospitals with variable sizes and resources, finding high levels of compliance. The study highlights the scalability and feasibility of the program, which aims to optimize care for older adults in a wide range of hospital settings.

SourceAmerican College of Surgeons·JournalJournal of the American College of Surgeons·DateApr 27, 2023

Growing number of states provide coverage for outpatient hemodialysis for undocumented immigrants

A growing number of states have implemented policies to cover outpatient hemodialysis for undocumented immigrants with kidney failure. This expansion may be due to increased awareness of poor outcomes with emergency hemodialysis and advocacy efforts. The move towards covering dialysis in all 50 states is called for by experts, who also...

SourceAmerican College of Physicians·JournalAnnals of Internal Medicine·TypeData/statistical analysis·DateApr 24, 2023

Achieving prevention and health, rather than more healthcare

Researchers found deaths from gallstone disease increased in younger populations and those with Medicaid after Medicaid expansion, highlighting the need for proactive prevention over reactive emergency care. A new healthcare model emphasizing primary care and prevention is proposed to address these inequities.

SourceRutgers University·JournalJournal of Surgical Research·TypeData/statistical analysis·DateApr 23, 2023

Does weight loss surgery harm adolescents’ bones?

A study found that sleeve gastrectomy decreases bone mineral density and strength in adolescents and young adults. Participants who underwent weight loss surgery lost significant amounts of weight and experienced reductions in abdominal fat tissue and muscle mass.

SourceWiley·JournalJournal of Bone and Mineral Research·DateApr 19, 2023

Risks of removing ovaries at benign hysterectomy may outweigh the benefits for women at low risk for ovarian cancer

Researchers found that removing ovaries during a benign hysterectomy increases the risk of hospitalization for cardiovascular disease in premenopausal women, but not necessarily for cancer. The study supports current recommendations to conserve ovaries in premenopausal patients at low risk for ovarian cancer.

SourceAmerican College of Physicians·JournalAnnals of Internal Medicine·TypeObservational study·DateApr 17, 2023

Balloon pulmonary angioplasty, a novel treatment for chronic blood clots in lung arteries, gives patients a new lease on life, Lewis Katz School of Medicine at Temple University study shows

A novel treatment approach called balloon pulmonary angioplasty has been shown to be effective in treating chronic blood clots in lung arteries. The procedure improves exercise capacity and quality of life, with some patients able to stop medications altogether. Refinements in technique have improved the procedure's safety and efficacy.

SourceTemple University Health System·JournalJACC Advances·DateApr 13, 2023

Assessing the accuracy of artery models

Hokkaido University researchers evaluate a material used to build model arteries, finding it suitable for medical education and surgical practice. The study also highlights the potential for improved assessment of 3D printing technology in creating highly accurate models of individual patient's artery structure.

SourceHokkaido University·JournalJournal of Vascular and Interventional Radiology·TypeExperimental study·DateApr 11, 2023

Early menopause, later start to hormone therapy may increase risk of Alzheimer’s disease

A new study from Mass General Brigham researchers found that early menopause may be a risk factor for Alzheimer's disease dementia. However, women who received hormone therapy around the time of menopause onset did not experience an increased risk of dementia. The study suggests that timing is crucial when it comes to hormone therapy, ...

SourceMass General Brigham·JournalJAMA·TypeObservational study·DateApr 3, 2023

New survey finds COVID-19 pandemic changed public’s view of obesity

A new survey found that nearly a third of Americans worry more about obesity due to COVID-19, with 28 million people considering weight loss methods. The survey also showed that nearly 90% with obesity have tried to lose weight at some point in their lives, but many underestimate the effectiveness of treatments like weight-loss surgery.

SourceAmerican Society for Metabolic and Bariatric Surgery·JournalSurgery for Obesity and Related Diseases·TypeSurvey·DateMar 22, 2023

Developing postoperative delirium is associated with a faster rate of cognitive decline

Developing postoperative delirium is associated with a 40% faster rate of cognitive decline compared to those who do not develop delirium. The study, which followed 560 older adults for up to six years, found that delirium influences every time point and is linked to sharper drops in cognition and faster declines over time.

SourceHebrew SeniorLife Hinda and Arthur Marcus Institute for Aging Research·JournalJAMA Internal Medicine·TypeObservational study·DateMar 20, 2023

Delaying treatment for localised prostate cancer does not increase mortality risk, trial shows

The ProtecT trial found that active monitoring of prostate cancer has the same high survival rates after 15 years as radiotherapy or surgery. Men on active monitoring were more likely to see their cancer progress, but this didn't reduce their likelihood of survival.

SourceEuropean Association of Urology·JournalNew England Journal of Medicine·TypeRandomized controlled/clinical trial·DateMar 11, 2023

Researchers describe hands-on treatments for patients with low back pain after lumbar spine surgery

A recent study found that spinal manipulation is a gentle therapy used to treat low back pain in patients after previous lumbar spine surgery. The study, published in Chiropractic & Manual Therapies, compiled data from over 100 patients and reported most cases were done using a potentially gentler method.

SourceUniversity Hospitals Cleveland Medical Center·JournalChiropractic & Manual Therapies·DateMar 9, 2023

Hospitals face challenges when implementing enhanced recovery programs for surgery

The study analyzed data from 151 hospitals that participated in an ISCR protocol for colorectal surgery to determine if they improved or worsened in complying with ERP process measures over an 18-month period. Key findings suggest a significant opportunity to improve compliance and patient outcomes, but inadequate resources and limited...

SourceAmerican College of Surgeons·JournalJournal of the American College of Surgeons·DateMar 8, 2023

Major medical organizations form a coalition to stem the rising tide of firearm violence using a comprehensive public health approach

Leading medical organizations have formed a coalition to combat the growing problem of firearm violence in the US. The Healthcare Coalition for Firearm Injury Prevention aims to promote education, advocacy, and community-centered approaches to reduce firearm-related injuries.

SourceAmerican College of Surgeons·JournalJournal of the American College of Surgeons·DateMar 6, 2023

Neoadjuvant pembrolizumab administered before surgery improves outcomes of melanoma patients

A phase 2 clinical trial shows that treating resectable stage 3 and 4 melanoma patients with pembrolizumab both before and after surgery greatly improves outcomes compared to pembrolizumab given only after surgery. This approach resulted in significantly longer event-free survival rates.

SourceH. Lee Moffitt Cancer Center & Research Institute·JournalNew England Journal of Medicine·TypeRandomized controlled/clinical trial·DateMar 1, 2023