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UPR-induced ovarian cancer cell fusion: a mechanism favoring drug resistance?

Researchers discuss chemotherapeutic resistance in recurring ovarian cancer, focusing on the unfolded protein response and its effect on polyploid giant cancer cells. Understanding this mechanism could lead to investigating cancer cell molecular mechanisms and potential therapeutic strategies.

SourceImpact Journals LLC·JournalOncoscience·TypeCommentary/editorial·DateMay 26, 2023

Computer‐aided diagnosis improves breast ultrasound expertise in multicenter study

A multicenter study found that deep learning-based computer-aided diagnosis significantly improved radiologists' diagnostic performance for breast lesion classification on ultrasound. The use of CAD resulted in a 6.0% upgrade of BI-RADS category 3 assessments to category 4A, with 16.7% being malignant.

SourceAmerican Roentgen Ray Society·JournalAmerican Journal of Roentgenology·TypeImaging analysis·DateMay 24, 2023
SAMSUNG T9 Portable SSD 2TB

SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.

Investing in safe surgery could cut costs and save lives in LMICs

A new study reveals that Surgical Site Infection (SSI) is a major financial burden on health services in LMICs, with patients experiencing higher costs for postoperative care. Investing in health technologies to reduce SSI could help improve healthcare quality and save lives.

SourceUniversity of Birmingham·JournalJournal of Hospital Infection·TypeRandomized controlled/clinical trial·DateMay 18, 2023

Engineers design sutures that can deliver drugs or sense inflammation

Researchers at MIT have designed new 'smart' sutures that can deliver drugs or sense inflammation after surgery. The bioderived sutures use hydrogel coatings to detect early warning signs of complications, such as Crohn's disease, and can also release therapeutic molecules to promote healing.

SourceMassachusetts Institute of Technology·JournalMatter·DateMay 16, 2023

Experts say it’s not yet time to take off masks in the health care setting

A new commentary from infectious disease experts emphasizes the importance of continued masking in healthcare settings due to low evidence of efficacy and high transmission risks. Despite recent conflicting views, the authors argue that mask-wearing remains a crucial strategy for infection prevention.

SourceAmerican College of Physicians·JournalAnnals of Internal Medicine·TypeObservational study·DateMay 15, 2023

NTU Singapore scientists discover why wavy wounds heal faster than straight wounds

Researchers at Nanyang Technological University found that cells near wavy shaped wounds moved in a swirling manner, while those near straight wounds moved in straight lines. This discovery reveals that the swirling motion is crucial for gap-bridging and accelerates wound healing in wavy wounds.

SourceNanyang Technological University·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateMay 14, 2023
CalDigit TS4 Thunderbolt 4 Dock

CalDigit TS4 Thunderbolt 4 Dock simplifies serious desks with 18 ports for high-speed storage, monitors, and instruments across Mac and PC setups.

Crossroads: The role of biomarkers in the management of lumps in the breast

Researchers discuss the importance of biomarkers in breast lump management, enabling patients to make informed decisions between proactive treatment and watchful waiting. The development of biomarkers could provide personalized risk assessments and guide treatment strategies for women with breast lumps.

SourceImpact Journals LLC·JournalOncotarget·TypeCommentary/editorial·DateMay 2, 2023
Apple iPhone 17 Pro

Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.

Endovascular treatment more likely to avoid amputation or death for limb-threatening artery disease

A randomized controlled trial shows that a best endovascular treatment first revascularisation strategy is more effective in preventing major amputation and death than a vein bypass first strategy for patients with chronic limb-threatening ischaemia. The study, BASIL-2, recruited 345 patients from the UK, Sweden, and Denmark and found ...

SourceUniversity of Birmingham·JournalThe Lancet·TypeRandomized controlled/clinical trial·DateMay 2, 2023

Obesity associated with increased risk of complications after surgery

New research published in the journal SURGERY found that obesity is associated with increased risk of complications following surgery, including infection, blood clots, and kidney complications. Patients with overweight or obesity had higher risk-adjusted odds of developing these post-operative outcomes compared to those of normal weight.

SourceUniversity of Colorado Anschutz Medical Campus·JournalSurgery·TypeData/statistical analysis·DateMay 1, 2023

Research shows that lymph node sampling during kidney tumor surgery is safe

Researchers analyzed outcomes for 144 Colorado patients who had lymph node sampling at the time of surgery for kidney tumors between 2005 and 2019. They found no statistically significant difference in clinically significant complications between patients who underwent more extensive lymph node sampling than those who didn’t.

SourceUniversity of Colorado Anschutz Medical Campus·JournalThe Journal of Urology·TypeData/statistical analysis·DateMay 1, 2023

Transgender women are still at risk for prostate cancer

A first-of-its-kind study has estimated that transgender women taking estrogen are at a higher risk for prostate cancer, with 14 cases per 10,000 people. The study found disparities in diagnosis rates among different racial groups.

SourceUniversity of California - San Francisco·JournalJournal of the American Medical Association·DateApr 29, 2023
GoPro HERO13 Black

GoPro HERO13 Black records stabilized 5.3K video for instrument deployments, field notes, and outreach, even in harsh weather and underwater conditions.

Improving geriatric surgical quality is feasible for a wide range of hospitals

A national pilot program evaluated the implementation of geriatric surgery standards in eight hospitals with variable sizes and resources, finding high levels of compliance. The study highlights the scalability and feasibility of the program, which aims to optimize care for older adults in a wide range of hospital settings.

SourceAmerican College of Surgeons·JournalJournal of the American College of Surgeons·DateApr 27, 2023

US and allies can learn from military medical lessons in Ukraine

The US military medical system is not ready to handle major conflicts with near-peer adversaries, who possess similar military capabilities. Prolonged field care training and strong patient data are crucial to address the challenges of evacuating wounded soldiers and providing specialized surgical care.

SourceAmerican College of Surgeons·JournalJournal of the American College of Surgeons·DateApr 24, 2023

Growing number of states provide coverage for outpatient hemodialysis for undocumented immigrants

A growing number of states have implemented policies to cover outpatient hemodialysis for undocumented immigrants with kidney failure. This expansion may be due to increased awareness of poor outcomes with emergency hemodialysis and advocacy efforts. The move towards covering dialysis in all 50 states is called for by experts, who also...

SourceAmerican College of Physicians·JournalAnnals of Internal Medicine·TypeData/statistical analysis·DateApr 24, 2023

Pushing frontiers through upcycling: eggshell waste for bone graft material

Researchers developed a method to convert eggshells into amorphous calcium phosphate particles, which were found to be safe, cell-friendly, and effective in promoting bone regeneration. The findings promise to create an eco-friendly alternative to commercialized xenograft materials.

SourceKeAi Communications Co., Ltd.·JournalSmart Materials in Medicine·TypeExperimental study·DateApr 23, 2023
Fluke 87V Industrial Digital Multimeter

Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.

Achieving prevention and health, rather than more healthcare

Researchers found deaths from gallstone disease increased in younger populations and those with Medicaid after Medicaid expansion, highlighting the need for proactive prevention over reactive emergency care. A new healthcare model emphasizing primary care and prevention is proposed to address these inequities.

SourceRutgers University·JournalJournal of Surgical Research·TypeData/statistical analysis·DateApr 23, 2023

Good news for patients waiting for stoma reversal surgery

A recent study led by Dr Rachael Rigby from Lancaster University found that delays in stoma reversal surgery do not impact on risk of complications or commensal microflora loss, atrophy, or scarring. However, a higher degree of microflora loss is associated with an increased risk of complications.

SourceLancaster University·JournalGut Microbes·TypeExperimental study·DateApr 20, 2023

Does weight loss surgery harm adolescents’ bones?

A study found that sleeve gastrectomy decreases bone mineral density and strength in adolescents and young adults. Participants who underwent weight loss surgery lost significant amounts of weight and experienced reductions in abdominal fat tissue and muscle mass.

SourceWiley·JournalJournal of Bone and Mineral Research·DateApr 19, 2023
Apple iPad Pro 11-inch (M4)

Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.

Risks of removing ovaries at benign hysterectomy may outweigh the benefits for women at low risk for ovarian cancer

Researchers found that removing ovaries during a benign hysterectomy increases the risk of hospitalization for cardiovascular disease in premenopausal women, but not necessarily for cancer. The study supports current recommendations to conserve ovaries in premenopausal patients at low risk for ovarian cancer.

SourceAmerican College of Physicians·JournalAnnals of Internal Medicine·TypeObservational study·DateApr 17, 2023
Davis Instruments Vantage Pro2 Weather Station

Davis Instruments Vantage Pro2 Weather Station offers research-grade local weather data for networked stations, campuses, and community observatories.

Balloon pulmonary angioplasty, a novel treatment for chronic blood clots in lung arteries, gives patients a new lease on life, Lewis Katz School of Medicine at Temple University study shows

A novel treatment approach called balloon pulmonary angioplasty has been shown to be effective in treating chronic blood clots in lung arteries. The procedure improves exercise capacity and quality of life, with some patients able to stop medications altogether. Refinements in technique have improved the procedure's safety and efficacy.

SourceTemple University Health System·JournalJACC Advances·DateApr 13, 2023

Bringing racial equity to kidney transplant evaluation

Medical University of South Carolina researchers streamlined kidney transplant evaluations to increase access for African Americans. They used telehealth and partnerships with local providers to help patients complete the evaluation process, resulting in higher numbers of African Americans beginning and completing the evaluation.

SourceMedical University of South Carolina·TypeData/statistical analysis·DateApr 11, 2023

Assessing the accuracy of artery models

Hokkaido University researchers evaluate a material used to build model arteries, finding it suitable for medical education and surgical practice. The study also highlights the potential for improved assessment of 3D printing technology in creating highly accurate models of individual patient's artery structure.

SourceHokkaido University·JournalJournal of Vascular and Interventional Radiology·TypeExperimental study·DateApr 11, 2023
DJI Air 3 (RC-N2)

DJI Air 3 (RC-N2) captures 4K mapping passes and environmental surveys with dual cameras, long flight time, and omnidirectional obstacle sensing.

Early menopause, later start to hormone therapy may increase risk of Alzheimer’s disease

A new study from Mass General Brigham researchers found that early menopause may be a risk factor for Alzheimer's disease dementia. However, women who received hormone therapy around the time of menopause onset did not experience an increased risk of dementia. The study suggests that timing is crucial when it comes to hormone therapy, ...

SourceMass General Brigham·JournalJAMA·TypeObservational study·DateApr 3, 2023

A bright spot in the treatment of lateral disc meniscus injuries in for youth

Researchers found that preserving the meniscus with sutures is more effective in protecting cartilage from future damage in younger patients. Meniscectomies, which remove more than half of the meniscus, were more likely to progress cartilage degeneration.

SourceOsaka Metropolitan University·JournalArchives of Orthopaedic and Trauma Surgery·TypeObservational study·DateMar 30, 2023
Nikon Monarch 5 8x42 Binoculars

Nikon Monarch 5 8x42 Binoculars deliver bright, sharp views for wildlife surveys, eclipse chases, and quick star-field scans at dark sites.

Surgical sealing made better with robust thermosensitive bioadhesives

Scientists developed an injectable biomaterial with improved adhesion, stretchability, and toughness, making it ideal for surgical wound sealing. The material showed superior adhesive strength, stability, and biocompatibility in physiological conditions.

SourceTerasaki Institute for Biomedical Innovation·JournalCell Reports Physical Science·TypeExperimental study·DateMar 29, 2023

Routine preoperative medical consultations don’t improve surgery outcomes

A large observational study found that most patients do not medically benefit from consultation with a medical specialist before their surgery. The study of 359,618 patients in Ontario suggested that preoperative medical consultations were an independent risk factor for death 30 days after surgery.

SourceThe Ottawa Hospital·JournalJAMA Internal Medicine·TypeData/statistical analysis·DateMar 27, 2023

How one state beat national surgery opioid trends

A statewide effort in Michigan resulted in a 56% reduction in opioid prescriptions after six common operations and a 26% drop in persistent opioid use. The achievement surpassed national trends, driven by voluntary prescribing guidelines and surgical team involvement.

SourceMichigan Medicine - University of Michigan·JournalAnnals of Surgery·TypeData/statistical analysis·DateMar 24, 2023
Celestron NexStar 8SE Computerized Telescope

Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.

New survey finds COVID-19 pandemic changed public’s view of obesity

A new survey found that nearly a third of Americans worry more about obesity due to COVID-19, with 28 million people considering weight loss methods. The survey also showed that nearly 90% with obesity have tried to lose weight at some point in their lives, but many underestimate the effectiveness of treatments like weight-loss surgery.

SourceAmerican Society for Metabolic and Bariatric Surgery·JournalSurgery for Obesity and Related Diseases·TypeSurvey·DateMar 22, 2023

Developing postoperative delirium is associated with a faster rate of cognitive decline

Developing postoperative delirium is associated with a 40% faster rate of cognitive decline compared to those who do not develop delirium. The study, which followed 560 older adults for up to six years, found that delirium influences every time point and is linked to sharper drops in cognition and faster declines over time.

SourceHebrew SeniorLife Hinda and Arthur Marcus Institute for Aging Research·JournalJAMA Internal Medicine·TypeObservational study·DateMar 20, 2023

Gender disparity in NIH funding among surgeon-scientists

Women surgeons remain underrepresented among NIH-funded surgeon-scientists over a 25-year period, despite early career success in receiving funding. This disparity underscores the necessity of targeted support to create a more diverse surgical research workforce.

SourceJAMA Network·JournalJAMA Network Open·DateMar 20, 2023

New technique reduces postoperative complications in prostate cancer surgery

A new technique involving a small flap in the peritoneum can reduce postoperative complications in prostate cancer surgery by allowing lymphatic fluid to escape and be absorbed. The study found that this technique significantly reduced the incidence of lymphocele, a common complication where lymphatic fluid collects in the pelvis.

SourceEuropean Association of Urology·DateMar 11, 2023
Creality K1 Max 3D Printer

Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.

Delaying treatment for localised prostate cancer does not increase mortality risk, trial shows

The ProtecT trial found that active monitoring of prostate cancer has the same high survival rates after 15 years as radiotherapy or surgery. Men on active monitoring were more likely to see their cancer progress, but this didn't reduce their likelihood of survival.

SourceEuropean Association of Urology·JournalNew England Journal of Medicine·TypeRandomized controlled/clinical trial·DateMar 11, 2023

UK study finds vasectomies are even safer than reported

A UK study reviewing over 90,000 vasectomies found that chronic scrotal pain occurs in just 0.2% of patients, while post-operative infection rates are around 1.6%. The study updates outdated figures and aims to encourage more men to undergo the procedure.

SourceEuropean Association of Urology·DateMar 11, 2023

Researchers describe hands-on treatments for patients with low back pain after lumbar spine surgery

A recent study found that spinal manipulation is a gentle therapy used to treat low back pain in patients after previous lumbar spine surgery. The study, published in Chiropractic & Manual Therapies, compiled data from over 100 patients and reported most cases were done using a potentially gentler method.

SourceUniversity Hospitals Cleveland Medical Center·JournalChiropractic & Manual Therapies·DateMar 9, 2023
Sky & Telescope Pocket Sky Atlas, 2nd Edition

Sky & Telescope Pocket Sky Atlas, 2nd Edition is a durable star atlas for planning sessions, identifying targets, and teaching celestial navigation.

Nearby food stores affect results after weight-loss surgery

Studies found an association between living close to higher-quality food stores and better weight loss outcomes after bariatric surgery. Living near low-diversity stores was linked to less sustained weight loss, while moderate- or high-diversity stores had no effect.

SourceOhio State University·JournalObesity Surgery·DateMar 9, 2023

Hospitals face challenges when implementing enhanced recovery programs for surgery

The study analyzed data from 151 hospitals that participated in an ISCR protocol for colorectal surgery to determine if they improved or worsened in complying with ERP process measures over an 18-month period. Key findings suggest a significant opportunity to improve compliance and patient outcomes, but inadequate resources and limited...

SourceAmerican College of Surgeons·JournalJournal of the American College of Surgeons·DateMar 8, 2023

FDA rule lowering drug dose is associated with less liver injury

A new study by Weill Cornell Medicine found that the FDA's mandate to limit opioid-acetaminophen combinations resulted in significant reductions in liver injuries. The mandate, implemented in 2014, limited the dosage of acetaminophen in these drugs, leading to a decline in hospitalizations and acute liver failure cases.

SourceWeill Cornell Medicine·JournalJAMA·DateMar 7, 2023

Algorithm predicts females have higher risk for kidney damage after aneurysm repair

A new algorithm predicts female patients are at higher risk for kidney damage after aneurysm repair, with those having reduced glomerular filtration rate facing a 4.7 times increased risk. The algorithm could help identify patients at risk and optimize them before surgery.

SourceMichigan Medicine - University of Michigan·JournalAnnals of Vascular Surgery·TypeData/statistical analysis·DateMar 7, 2023
Kestrel 3000 Pocket Weather Meter

Kestrel 3000 Pocket Weather Meter measures wind, temperature, and humidity in real time for site assessments, aviation checks, and safety briefings.

Spinal cord stimulation doesn’t help with back pain, says new review

A new review found that spinal cord stimulation is no better than a placebo for treating low back pain, with probably little to no benefit for people with the condition. The review also highlighted gaps in clinical data and called for future trials to be longer and more comprehensive.

SourceUniversity of Sydney·JournalCochrane Database of Systematic Reviews·TypeSystematic review·DateMar 7, 2023

Major medical organizations form a coalition to stem the rising tide of firearm violence using a comprehensive public health approach

Leading medical organizations have formed a coalition to combat the growing problem of firearm violence in the US. The Healthcare Coalition for Firearm Injury Prevention aims to promote education, advocacy, and community-centered approaches to reduce firearm-related injuries.

SourceAmerican College of Surgeons·JournalJournal of the American College of Surgeons·DateMar 6, 2023
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C)

Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C) keeps Macs, tablets, and meters powered during extended observing runs and remote surveys.

Existing chest scans offer new opportunities for predicting surgical risks

Researchers found that patients with greater buildup of fatty plaque deposits in the heart's three largest blood vessels had higher chances of developing serious health issues following surgery. This study suggests using existing chest scans to estimate patients' risk of heart attack or death during major surgeries.

SourceNYU Langone Health / NYU Grossman School of Medicine·DateMar 2, 2023