Articles tagged with Surgery
Researchers describe the use of ripretinib and repeated surgical resection in a patient with recurrent GIST harboring a KIT exon 11 mutation. The treatment led to extended clinical benefit, outperforming current reported data from ripretinib clinical trials.
A new smartphone app using the APRI+ALBI score increases the safety of liver surgery by providing an individualized risk assessment for patients prior to resection. The score offers a cheaper and less invasive option with comparable predictive power compared to standard preoperative tests.
Researchers at Children's Hospital Los Angeles have developed a novel app called the CHALF score to predict if a child with acute liver failure needs a transplant. The tool assesses liver failure risk on a scale of 5-60 and has been shown to accurately predict patient outcomes.
A new AI-based tool estimates patient-specific cancer survival rates using machine learning, offering personalized prognosis for patients with breast, thyroid, and pancreatic cancers. The Cancer Survival Calculator differs from existing estimators by incorporating multiple factors beyond disease stage.
Childhood trauma rates surged during the pandemic, with injuries from motor vehicle crashes and gunshot wounds rising disproportionately in socioeconomically deprived areas. The study highlights worsened pandemic-related stressors exacerbating an already severe problem.
A new study presents evidence that school redistricting is linked to spikes in shooting-related injuries in urban areas, with a 14% increase in incidents during redistricting events. The study suggests that social destabilization caused by redistricting may contribute to the increased violence.
The American College of Surgeons (ACS) Clinical Congress 2023 offers media credentials to cover groundbreaking research, connect with surgeon experts, and learn about the latest trends in surgery. Key topics include artificial intelligence, COVID-19's impact on cancer care, and pediatric trauma.
A new study published in JNCCN found that intensive local-regional treatment to remove as much tumor as possible did not significantly impact overall quality of life for patients with metastatic colorectal cancer. However, the treatment was associated with a higher risk of adverse events.
Researchers conducted a randomized trial in Canadian ICUs, finding that switching to small-volume blood collection tubes lowered red blood cell transfusion rates. The study suggests this change may improve patient outcomes and reduce the need for transfusions.
A new clinical trial has shown that infusing immune cells from living donors into recipients before transplantation may reduce the need for lifelong immunosuppressant medication. The treatment involves infusing donor-derived regulatory dendritic cells, which help the recipient's immune system distinguish between foreign and self-cells.
A new blood test called OvaPrint TM detects specific nucleic acids in the blood, distinguishing between cancerous and benign pelvic masses with high accuracy. The test has the potential to improve treatment outcomes by identifying the best surgical approach for patients with a pelvic mass.
Middle-aged Chinese surgery patients experience subjective cognitive impairment within 12 months after surgery, with identified risk factors. Preoperative psychological interventions and optimized perioperative management may help prevent postoperative cognitive impairment.
The study developed a highly accurate AI model for fully automated cancer detection, including small and difficult-to-detect tumors. The model could detect visually imperceptible cancer from normal-appearing pancreases substantially early before clinical diagnosis, with a median of 438 days.
A new study published in JAMA found that a consensus-based risk-stratification algorithm reduced unnecessary ovary removals in girls with benign masses from 16.1% to 8.4%. The algorithm accurately identified lesions highly likely to be benign, allowing for ovary-sparing surgery.
Men with metastatic prostate cancer in Sweden experienced an average survival rate increase of six months after dual treatment was introduced from 2016 onwards. This improvement coincides with the gradual rollout of 'dual treatment', combining standard hormone therapy and chemotherapy or androgen receptor blockers.
Leading professional organizations announce first-time multidisciplinary consensus guidelines for essential and comprehensive care centers in the US. The guidelines aim to address known variation in outcomes at different centers, providing structure, process, and outcome components necessary for quality care.
A study by UC San Francisco researchers found that patients with acute kidney injury on outpatient dialysis may not need lifelong treatment if they have the potential to recover. The study tracked data from over 1,700 patients and showed that approximately three-quarters of those who recovered kidney function discontinued dialysis with...
A new clinical and research partnership has created an AI model that can predict whether cancerous tissue has been fully removed from the body during breast cancer surgery. The model performed as well as humans in identifying positive margins, especially in patients with higher breast density.
Researchers have identified a specific error in the NOTCH1 gene that causes rare kidney cancer reninoma. The study found that using existing drugs targeting this gene could serve as an alternative treatment for patients where surgery is not recommended.
Researchers developed a scoring system analyzing income, education, geographical location, access to care, and other factors to identify patients at increased risk of poor outcomes. The study found significant socioeconomic disadvantage associated with a 21% decrease in textbook outcomes and a 32% decrease in overall survival.
The Massive Transfusion in Children-II (MATIC-II) clinical trial will test multiple interventions for life-threatening bleeding in children. The trial aims to determine the most effective and safe bundle of care for pediatric trauma patients, with a focus on precision transfusion medicine.
A study comparing PI-RADS 2.0 and 2.1 found no significant differences in upgrade (29% vs. 22%) or downgrade (19% vs. 21%) rates from targeted biopsy to radical prostatectomy, suggesting no improvement in prostate cancer grade assessment with the latest PI-RADS update.
Researchers found a 55% reduction in lymphoma risk and a 40% overall reduction in blood cancer risk among bariatric surgery patients. Women with high blood sugar at the start of the study benefited most from the surgery.
The AAO-HNSF 2023 Annual Meeting & OTO Experience will feature groundbreaking clinical research and professional development emerging within otolaryngology. The meeting will showcase the latest scientific oral presentations on various topics, including Otology, Laryngology, Endocrine Surgery, and more.
Patients with stage 1-3 non-small cell lung cancer treated with combination immunotherapy before surgery had a better major pathological response rate than those receiving single-agent therapy alone. The NeoCOAST platform trial found that targeting multiple cancer pathways through therapy may be superior to a single treatment.
Researchers analyzed data from 2005-2020 and found that 10-year conditional survival was similar between biventricular and most single-ventricle CHD patients. Biventricular CHD patients also showed better 10-year survival compared to non-CHD heart transplant recipients.
Patients treated by female surgeons have a lower risk-adjusted likelihood of adverse postoperative outcomes at 90 days and one year following surgery. The study of over one million patients suggests differences in patient outcomes based on physician sex warrant further investigation into underlying causes and potential solutions.
A Swedish study of 150,000 patients found female surgeons achieved better outcomes and operated more slowly than their male counterparts. The results may shed light on gender differences in the surgical specialty.
A tailored exercise program starting three to six weeks after shoulder surgery is the best approach for preventing a secondary shoulder dislocation. Patients who embark on such a program are twice as likely to avoid a recurrent injury than those using exercise alone.
The COP-AF trial tested colchicine's effect on perioperative atrial fibrillation and myocardial injury after non-cardiac surgery. The study found no significant reduction in these complications, but showed encouraging signs of benefit for cardiovascular outcomes.
Gender-affirming surgeries in the US increased nearly threefold from 2016 to 2019, with breast and chest procedures being the most common. The number of genital surgical procedures performed rose with increasing age, indicating a growing trend among older individuals seeking gender-affirming care.
Researchers found a significant increase in pediatric trauma admissions during the COVID-19 pandemic, with younger patients and falls from moderate heights being more common. Blood alcohol levels were also higher in patients aged 14-18 years old, suggesting targeted interventions to curb alcohol use may be needed
A recent study found that cast immobilization is as effective as surgery in treating older adults with arm fractures. After one year, no statistically significant differences were found between the groups in terms of disability or range of motion. The study included 276 patients aged 70–89 years who suffered a distal radius fracture.
A randomized clinical trial found that a preoperative augmented reality walkthrough decreased preoperative anxiety compared to traditional education and handouts. However, there was no significant impact on postoperative anxiety, pain levels, or narcotic use in patients undergoing surgery.
A first-in-human trial of deep brain stimulation (DBS) for post-stroke rehabilitation patients has shown that DBS to target the dentate nucleus improves motor impairment and function, with gains nearly tripling initial scores. The study also found significant improvements in quality of life.
A survey study found that gender-affirming mastectomies result in low levels of decisional regret and high satisfaction among patients. This suggests that current validated instruments may not be suitable for assessing post-surgical outcomes.
Critically ill children on ventilator support can experience patient-ventilator asynchrony (PVA), which worsens outcomes. Researchers are using machine learning to develop a common set of definitions and measurements for PVA in pediatric patients, aiming to minimize risks and improve clinical outcomes.
Researchers highlight the need for effective treatment strategies for adenoid cystic carcinoma (ACC) of the head and neck, which is a highly malignant tumor with variable localizations. Proton therapy shows decisive advantages in long-term survival rates for ACC.
A new Harvard-led research suggests that the thymus, often considered expendable in adults, actually plays a crucial role in maintaining adult immune health and preventing cancer. The study found that patients who had their thymus removed had a nearly threefold higher risk of death from various causes, including cancer.
A new study found that 81% of women report persistent GI symptoms years after diagnosis, with abdominal bloating and gas being the most common. The analysis also showed that severe GI symptoms are linked to poor quality of life, social activities, and body image satisfaction.
A large clinical trial found that surgery does not increase the number of days patients with advanced cancer are alive and out of the hospital, but improves symptoms and quality of life. Patients who underwent surgery reported fewer bowel-related symptoms after leaving the hospital.
A new open-source software, NMSM Pipeline, enables clinicians and engineers to create personalized computer models of patient movement to optimize treatment designs. The software uses physics-based models to predict and optimize functional outcomes for patients with various mobility impairments.
PSMA PET imaging provides prognostic information on cancer recurrence risk before treatment, improving personalized treatments and guiding surgical plans. The tool outperforms current standard tests in predicting biochemical recurrence, a critical factor in determining cancer-specific mortality.
A recent study found that major US cities with larger proportions of Black residents are more likely to be affected by mass shooting events. The research suggests that addressing factors associated with structural racism could help prevent such incidents and reduce gun violence.
A new study by researchers at the National Institutes of Health found that women diagnosed and treated for breast cancer have increased biological aging compared to those who remain free of breast cancer. Radiation therapy showed the strongest association with faster biological aging, while surgery had no effect.
A team of UVA Health experts warns that surgeon-scientists are struggling to obtain research funding, which could lead to a decline in innovations for patients. The researchers found that internal medicine trainees are six times more likely to secure R01 grants and career development awards.
A multidisciplinary team implemented a quality improvement project to reduce hypothermia in NICU babies before, during, and after surgery. The project resulted in significant decreases in intraoperative and postoperative hypothermia rates, demonstrating the effectiveness of standardized temperature monitoring and thermal support.
A University of Otago study reveals that pre-operative high-intensity interval training can significantly improve patient outcomes after surgery, with a 56% reduction in post-operative complications. The study also found that participants who underwent HIIT prior to surgery stayed in the hospital for three fewer days on average.
A study by Potnuru et al. found cannabis use disorder associated with modestly increased perioperative morbidity and mortality after major elective surgery. The findings support preoperative screening for cannabis use disorder to inform risk stratification.
A new study published in Human Reproduction found that women with endometriosis are more likely to experience a reduction in live births before receiving a definitive diagnosis. The research, which included over 18,000 women with surgically-confirmed endometriosis, showed that the number of first live births among these women was half ...
A systematic review and meta-analysis of 12 studies found that preoperative high-intensity interval training improves cardiorespiratory fitness. The study also suggests that this type of training may reduce postoperative complications among adults undergoing major surgery, supporting its inclusion in pre-habilitation programs.
A new device combines rapid hemorrhage management, infection control, and sensing capabilities for long-term monitoring. The device features a tunable biodegradation rate and can detect bleeding in real-time using a nanowire-based capacitive sensor.
A 12-year study by Pennington Biomedical researchers found that metabolic surgery provides better results, less regression, compared to medical or lifestyle intervention for patients with class 1 obesity. The study showed significant improvements in glycemic control and weight loss, with high rates of diabetes remission.
A new study suggests that more women should be aware of the potential for revision surgery after cosmetic breast augmentation. The researchers found that those who consider themselves healthier and have higher levels of education are less likely to undergo or recommend the procedure.
A study found that even insured patients with diabetes use crowdfunding platforms like GoFundMe to cover excess medical expenses, including uncovered co-pays and life-saving care. Researchers urge policymakers to consider these needs when developing affordable diabetes care policies.
A network meta-analysis of 10 studies found expert panel-based and computer-based aesthetic outcome evaluation scored lower than patient-perceived outcomes. Standardization of tools with racially and culturally inclusive patient-reported measures is needed to improve clinical assessment of breast cancer patients.
The Lancet Commission proposes three priority areas for surgery: addressing trauma, congenital anomalies, and non-communicable diseases, while promoting inclusion and diversity in research. Surgery has a key role in global health challenges, and moving towards net-zero operating practices could reduce carbon emissions.
Metabolic and bariatric surgery use among US youth increased significantly from 2020 to 2021, rising by 50% compared to pre-pandemic years. Adults saw a decline in MBS rates during the same period, highlighting shifts in healthcare access and utilization.
A phase 3 trial found that extending lymphadenectomy beyond the standard procedure does not reduce disease recurrence or improve survival in patients with locally advanced bladder cancer. Instead, it increases the risk of adverse events and post-surgical death.
A recent study compared robotic and laparoscopic surgery for gastric cancer, finding that robotic surgery has superior short-term outcomes but comparable long-term results. The authors suggest considering 3D/4K displays over traditional 2D displays as a more favorable alternative for those without robotic capabilities.