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Findings of study on how illegally manufactured fentanyl enters U.S. contradict common assumptions, undermining efforts to control supply

A recent study by Carnegie Mellon University found that illegally manufactured fentanyl primarily enters the US via counties along the Canadian border. The analysis revealed these counties accounted for over 40% of large fentanyl seizures in 2023-2024, despite comprising only 3.1% of the national population. This finding undermines eff...

SourceCarnegie Mellon University·DateJul 7, 2025
SAMSUNG T9 Portable SSD 2TB

SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.

Pitt receives new grant to improve opioid use disorder treatment

The University of Pittsburgh School of Pharmacy's PERU has received a $7.8 million grant to develop and implement measurement-based care into community opioid treatment programs across Pennsylvania. This project aims to improve treatment access, promote recovery, and reduce fatal overdoses by addressing patient needs through personaliz...

SourceUniversity of Pittsburgh·DateJan 30, 2024

The fourth wave of the US overdose crisis: fentanyl and stimulants

US overdose deaths involving fentanyl and stimulants have increased by 50-fold since 2010, with stimulants becoming the most common drug class found in fentanyl-involved overdoses. The rise poses new challenges for healthcare providers due to the complexity of treating polysubstance use.

SourceSociety for the Study of Addiction·JournalAddiction·TypeObservational study·DateSep 14, 2023

Xylazine appears to worsen the life-threatening effects of opioids in rats

A new NIH study suggests xylazine, a veterinary tranquilizer, can damage brain oxygen levels when combined with opioid drugs like fentanyl and heroin. This combination may lead to prolonged brain oxygen decreases, increasing overdose risk. Researchers hope to develop interventions to reverse overdoses and save lives.

SourceNIH/National Institute on Drug Abuse·JournalPsychopharmacology·DateJun 20, 2023
Rigol DP832 Triple-Output Bench Power Supply

Rigol DP832 Triple-Output Bench Power Supply powers sensors, microcontrollers, and test circuits with programmable rails and stable outputs.

Graphene sensor rapidly detects opioid metabolites in wastewater

A novel graphene-based field effect transistors (FETs) device can detect four different synthetic and natural opioids at once in wastewater. The device uses aptamers to trap opioid metabolites, enabling real-time monitoring with high geographical resolution and low cost.

SourceBoston College·JournalACS Nano·TypeExperimental study·DateFeb 25, 2022
Apple iPhone 17 Pro

Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.

Opium linked with more deaths after bypass surgery

A large study found that continuing opium use after bypass surgery increases the risk of death, heart attack, and other adverse events. Stopping opium use is safe and may even be beneficial, according to researchers.

SourceEuropean Society of Cardiology·JournalEuropean Journal of Preventive Cardiology·DateJul 16, 2020

Traces of opiates found in ancient Cypriot vessel

Researchers at University of York and British Museum discovered traces of opiates in a sealed vessel dating back to Late Bronze Age. The presence of opiate alkaloids suggests that the vessel may have been used for medicinal or ceremonial purposes.

SourceUniversity of York·DateOct 2, 2018

Synthesis of opium alkaloids using electric current

Researchers at Johannes Gutenberg University Mainz have developed an electrochemical synthesis method for thebaine, overcoming decades-long challenges in mimicking its natural formation. The new approach uses astute modification of starting materials to achieve high selectivity and efficiency in the reaction.

SourceJohannes Gutenberg Universitaet Mainz·JournalAngewandte Chemie International Edition·DateJun 28, 2018

Breaking good -- Key discovery made for battling opioid epidemic

A novel gene encoding the enzyme thebaine synthase has been isolated from the opium poppy, enabling the commercial production of non-plant based biosynthetic manufacturing systems for active opioid agents and intermediates. This breakthrough opens the door to creating new opioid molecules with reduced addictiveness.

SourceEpimeron Inc.·JournalNature Chemical Biology·DateMay 30, 2018
Garmin GPSMAP 67i with inReach

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Researchers discover how opium poppies synthesize morphine

University of Calgary scientists have characterized a novel gene that encodes the gateway enzyme in the formation of morphine. This discovery could lead to the development of alternative painkillers, such as codeine and oxycodone.

SourceUniversity of Calgary·JournalNature Chemical Biology·DateJul 13, 2015

Alcohol and drugs: Not just for modern man

Research reveals prehistoric Europeans consumed psychoactive plants and fermented beverages in rituals to connect with the spirit world. Archaeological evidence suggests socially controlled use of these substances, contrasting with modern hedonistic views.

SourceSpringer Science+Business Media·JournalJournal of Archaeological Method and Theory·DateMay 12, 2014
Apple Watch Series 11 (GPS, 46mm)

Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.

Unlocking the opium poppy's biggest secret

Researchers have discovered the unique genes responsible for codeine and morphine production in the opium poppy, opening doors to alternative methods of producing these painkillers. The findings could lead to more efficient and cost-effective synthesis of pharmaceuticals using microorganisms.

SourceUniversity of Calgary·JournalNature Chemical Biology·DateMar 14, 2010

Modern technology helps shed light on illnesses in artists of the past

This article explores how diseases, drugs, and chemicals affected famous artists such as Michelangelo, Edvard Munch, Ivar Arosenius, and Vincent van Gogh. Clinical laboratory analysis is providing new insights into their creative achievements.

SourceDonna Krupa Public Relations·JournalArchives of Pathology & Laboratory Medicine·DateNov 16, 2005

As morphine turns 200, drug that blocks its side effects reveals new secrets

A new understanding of morphine's side effects has been gained through the discovery of methylnaltrexone, a peripheral opiate antagonist. This breakthrough allows scientists to distinguish between morphine's central analgesic and peripheral side effects, offering new hope for patients experiencing severe nausea, itching, and constipation.

SourceUniversity of Chicago Medical Center·DateMay 19, 2005
Sony Alpha a7 IV (Body Only)

Sony Alpha a7 IV (Body Only) delivers reliable low-light performance and rugged build for astrophotography, lab documentation, and field expeditions.