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Life Sciences

Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.

447,757 articles | 2542 topics

Health and Medicine

Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.

431,843 articles | 751 topics

Social Sciences

Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.

260,756 articles | 745 topics

Physical Sciences

Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.

257,913 articles | 1552 topics

Applied Sciences and Engineering

Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.

225,386 articles | 998 topics

Scientific Community

Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.

193,043 articles | 157 topics

Space Sciences

Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.

29,662 articles | 175 topics

Research Methods

Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.

21,889 articles | 139 topics

Mathematics

Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.

3,023 articles | 113 topics

Pushing through brain barriers

A Case Western Reserve University engineering professor is developing a miniaturized low-power device to detect how electrical signals and neurotransmitters in the brain work. The device will record 16 channels of chemical and electrical neural activity, measuring neurotransmitters and action potentials in real time.

Novel electric signals in plants

Researchers at the Max Planck Institute for Chemical Ecology have discovered a new electrical signal transmission system in plants called 'system potential', which is induced by wounding and can carry different information. This novel system allows plants to rapidly respond to insect herbivory and activate their defense mechanisms.

Garmin GPSMAP 67i with inReach

Garmin GPSMAP 67i with inReach provides rugged GNSS navigation, satellite messaging, and SOS for backcountry geology and climate field teams.

Rice psychologist explores perception of fear in human sweat

Research by Denise Chen reveals that human sweat contains emotional meanings, particularly in ambiguous situations, and modulates vision to detect fear. The study found that exposure to 'fearful' sweat biases women towards interpreting facial expressions as more fearful, especially when emotions are unclear.

New and unexpected mechanism identifies how the brain responds to stress

Researchers at the University of Calgary have identified a new stress response mechanism in the brain, where stress triggers a protein that removes the ability to slow down the stress response. This finding may lead to a better understanding of the changes in sensitivity to stress resulting from chronic exposure.

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'Lab on a chip' mimics brain chemistry

Scientists develop micro-scale tool to study how nerve cells in the brain work together, providing insights into growth and signaling molecules. The 'lab on a chip' system helps researchers understand complex interactions between neurons and their environment.

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Adult brain cells rediscover their inner child

Researchers at Johns Hopkins Medicine have found that newly made nerves in an adult brain's learning center experience a one-month period of child-like learning. This discovery suggests that new adult nerves play a deeper role than simply replacing dead ones, and may help explain how adults adapt to new experiences.

Organizing dumbbells for nanotech devices

Scientists design molecular machines that can switch between functional units and demonstrate reversible switching behavior when exposed to acid and base. The study showcases the potential for organizing molecular machines on surfaces, paving the way for future development of molecular computers.

Scent of fear impacts cognitive performance

A Rice University study found that women exposed to chemicals from fear-induced sweat performed more accurately on word-association tasks than those in neutral or no-sweat conditions. This suggests that human olfaction can detect chemical signals from fear, leading to more cautious behavior and improved accuracy.

Sony Alpha a7 IV (Body Only)

Sony Alpha a7 IV (Body Only) delivers reliable low-light performance and rugged build for astrophotography, lab documentation, and field expeditions.

Two studies offer clues about how alcoholic behavior is 'switched' on

Researchers found that increasing dopamine D2 receptors can reduce drinking behavior in mice and rats, while blocking another type of dopamine receptor may also decrease consumption. These findings provide insight into the complex roles of dopamine in alcohol abuse and may lead to molecular-based treatments.

Two enzymes key to calorie-burning, Brown research shows

Researchers at Brown Medical School have discovered two key enzymes, PC1 and PC2, that play a crucial role in processing the precursor of thyrotropin-releasing hormone (TRH) and regulating calorie-burning. This finding will aid in the understanding and treatment of obesity, which affects nearly 68 million adults in the United States.

Sequential signals choreograph embryonic tubule formation

Research found that hepatocyte growth factor (HGF) coordinates cellular behaviors for tubule development through sequential regulation of ERK and matrix metalloproteases. The study used MDCK cells to examine molecular events during tubulogenesis, revealing distinct regulatory subprograms acting at different times.

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Signal chemical primes plants for pest attack

Researchers discover green leafy volatiles (GLV) prime corn plant defenses to respond more strongly against subsequent herbivorous insect attacks. The primed plants produce chemical signals that attract natural parasites and predators, increasing crop protection.

Naked mole-rats bare pain relief clues

Researchers found naked mole-rats naturally lack Substance P, a neurotransmitter that sends pain signals to the central nervous system. Introducing Substance P restored pain signaling in these animals, sparking hope for new therapies to treat fibromyalgia.

Neural biology explains ejaculation

Researchers have identified a group of cells in the spinal cord that control ejaculation, which can be manipulated to treat sexual dysfunction. The discovery has implications for paraplegic men and those experiencing ejaculatory problems.

Sperm use heat sensors to find the egg

Researchers at Weizmann Institute find that sperm are attracted to fertilization site by temperature difference. A temperature-driven mechanism, known as thermotaxis, guides the sperm through the fallopian tube and prepares them for penetration of the egg.

Apple iPhone 17 Pro

Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.

Gene therapy reduces drinking in "alcoholic" rats

Researchers developed a gene therapy that increased D2 receptor levels in rats, leading to a significant drop in alcohol intake. The treatment showed promise in reducing drinking preference and behavior in both groups of rats.

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Apple AirPods Pro (2nd Generation, USB-C) provide clear calls and strong noise reduction for interviews, conferences, and noisy field environments.

'Opto-chips' are high-speed communications breakthrough

New polymers enable polymeric electro-optic modulators to translate electrical signals into optical signals at rates of up to 100 gigabytes per second, increasing information-processing speeds by 10 times those of current electronic devices.

Low voltage, high bandwidth telecommunications device reported inScience

Researchers have created a device that converts electric signals into optical transmissions at 100 gigabytes per second, eliminating download time and increasing efficiency. The breakthrough technology has the potential to transform fiber optic telecommunications and enable applications such as aircraft navigation and smart cars.

'Sun-glasses' in the eye

Researchers at Max Planck Institute for Brain Research discovered a protein in photoreceptor cells that plays a crucial role in adapting to changing light intensities. The activation of this autoreceptor triggers a negative feedback loop, reducing glutamate release and preventing signal saturation.

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Nikon Monarch 5 8x42 Binoculars deliver bright, sharp views for wildlife surveys, eclipse chases, and quick star-field scans at dark sites.

Increased Interest In "Smart" Materials Is Reported

Researchers are developing smart materials for various applications, including artificial limbs that can pick up objects, gel implants that release drugs as needed, and bridge models that prevent structural damage. These advancements could save lives by preventing accidents and improving safety in infrastructure.

Learning To Feel Chronic Pain

Researchers found that the brain enhances pain signals through silent synapses, which can lead to persistent pain. Blocking these pathways may lead to better treatments for chronic pain.

Scientists Discover A Secret Of Bacterial Communication

Researchers have identified a key chemical message that triggers the formation of biofilms, complex communities of bacteria that are notoriously resistant to antibiotics. This discovery could lead to the development of more effective treatments for bacterial infections.

Meta Quest 3 512GB

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Mathematics Reveals New Pattern Of Brain Cell Activity

Mathematicians at Ohio State University discovered two new electrochemical activity patterns in brain cells, which may help explain normal sleep changes and nervous system disorders like epilepsy. The research reveals that inhibitory signals can produce smooth waves, contrary to previous assumptions.

Female Fireflies Lure Males For Defense Chemical

In a surprising twist, female Photuris fireflies lure male Photinus fireflies close enough to eat them, obtaining defensive chemicals called lucibufagins. These compounds help females repel predators like spiders and birds.

OHSU Scientists Shed Light On Learning And Memory

Researchers at Oregon Health & Science University shed light on the molecular mechanisms underlying long-term potentiation, a key process for memory formation. The study reveals that CaM-KII plays a critical role in this process, enabling persistent changes in synaptic strength and storage of information.