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Life Sciences

Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.

447,757 articles | 2542 topics

Health and Medicine

Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.

431,843 articles | 751 topics

Social Sciences

Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.

260,756 articles | 745 topics

Physical Sciences

Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.

257,913 articles | 1552 topics

Applied Sciences and Engineering

Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.

225,386 articles | 998 topics

Scientific Community

Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.

193,043 articles | 157 topics

Space Sciences

Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.

29,662 articles | 175 topics

Research Methods

Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.

21,889 articles | 139 topics

Mathematics

Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.

3,023 articles | 113 topics

Vitamin D tied to muscle power in adolescent girls

A new study found a positive relationship between vitamin D levels and muscle power, force, velocity, and jump height in adolescent girls. The researchers measured serum vitamin D levels in 99 adolescent girls and used jumping mechanography to assess muscle power.

BUSM researcher solves mystery of 9-month-old

A 9-month-old breast-fed infant was diagnosed with rickets caused by vitamin D deficiency after presenting with seizures and a bulging soft spot. The case study published in the New England Journal of Medicine highlights the importance of considering nutritional deficiencies in infants, particularly those who are solely breast-fed.

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Seasonal variation in blood pressure

A French study of 8801 elderly participants found significant seasonal variations in systolic and diastolic blood pressure according to outdoor temperature. The authors advise careful monitoring and antihypertensive treatment during extreme temperatures, particularly in the elderly, who are at higher risk of cardiovascular events.

Vitamin D is the 'it' nutrient of the moment

A recent review article found that adequate vitamin D intake may prevent or delay diabetes onset and reduce complications for those diagnosed. Vitamin D plays a crucial role in insulin sensitivity and secretion, and deficiency is common among Americans with diabetes.

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Lack of vitamin D causes weight gain and stunts growth in girls

A Canada-US study published in Journal of Clinical Endocrinology & Metabolism found that insufficient vitamin D can cause higher body mass and shorter stature in girls during puberty. The researchers discovered a significant association between low vitamin D levels and increased abdominal fat, but no link to bone strength.

Vitamin D found to fight placental infection

Researchers at UCLA found that vitamin D stimulates cathelicidin production in placental tissues, enhancing antibacterial responses and protecting trophoblast cells from infection. The study suggests that pregnant women supplementing with vitamin D may enhance placental innate immunity.

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Lack of vitamin D could spell heart trouble

A growing body of evidence links low vitamin D levels to common CVD risk factors such as hypertension, obesity and diabetes. Researchers recommend screening and treating vitamin D deficiency in patients with risk factors for heart disease or diabetes.

'Let the sunshine in' to protect your heart this winter

A new review article in Circulation highlights the link between vitamin D deficiency and heart disease, with rates of severe disease or death potentially 30-50% higher among sun-deprived individuals. Treatment options such as vitamin D supplements may help decrease the risk of cardiovascular disorders.

Study helps clarify role of vitamin D in cancer therapy

Research reveals vitamin D's role in regulating colon cancer cell behavior by modulating gene expression and cytoskeleton structure. The study highlights a previously unknown pathway governing vitamin D's diverse effects on cancer cells.

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Could vitamin D save us from radiation?

Research suggests that vitamin D, specifically its active form calcitriol, could offer protection against radiation-induced damages by regulating cell cycle and proliferation. This could be a potential safe agent for protecting people before or after low-level nuclear incidents.

Lack of vitamin D linked to Parkinson's disease

A new study from Emory University School of Medicine found that 55 percent of Parkinson's disease patients had insufficient levels of vitamin D. The study also showed a higher fraction of patients with the lowest levels of vitamin D, described as deficiency, in the Parkinson's group compared to Alzheimer's and healthy groups.

Vitamin D deficiency may be more common in Parkinson's disease patients

A study published in Archives of Neurology found that individuals with Parkinson's disease are more likely to be vitamin D deficient compared to healthy adults and those with Alzheimer's disease. The average vitamin D concentration in the group with Parkinson's disease was lower than both groups.

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Oral vitamin D may help prevent some skin infections

A study found that oral vitamin D supplements increased cathelicidin production in the skin of patients with atopic dermatitis, a common form of eczema. This increase helped to correct a defect in the immune system and reduce the risk of skin infections.

Weight loss surgery may be associated with bone loss

Researchers found significant declines in hip bone mineral density after gastric bypass surgery, associated with the extent of weight loss. Calcium and vitamin D deficiencies may be due to alterations in the gastrointestinal tract during these procedures.

New mushroom study shows the power of energy density

A new study by Dr. Lawrence Cheskin suggests that increasing mushroom intake can help prevent or treat obesity by consuming low-energy-density foods in place of high-energy-density foods like lean ground beef. Mushroom meals were found to be as palatable and appealing as meat meals, with no difference in appetite or satiety.

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Low vitamin D levels pose large threat to health

Researchers found a 26% increased risk of death among individuals with low blood levels of vitamin D. The study suggests that adequate vitamin D levels may be crucial in preventing cardiovascular disease.

Low vitamin D levels associated with increased risk of death

Individuals with low vitamin D levels have a higher risk of death from all causes, according to a study analyzing data from the Third National Health and Nutritional Examination Survey. The analysis found that those with vitamin D deficiency had a 26% increased rate of death compared to those with adequate levels.

Low vitamin D levels associated with death from cardiovascular, all causes

A study of 3258 patients found that low blood levels of vitamin D were associated with a higher risk of death from cardiovascular causes and all causes. Individuals with lower vitamin D levels had higher rates of mortality, including those due to coronary artery disease, hypertension, and cardiovascular events.

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Study links vitamin D to colon cancer survival

A new study by scientists at Dana-Farber Cancer Institute found that patients diagnosed with colon cancer who had abundant vitamin D in their blood were less likely to die during a follow-up period. The researchers identified 304 participants and followed them until death or 2005, whichever occurred first.

Vitamin D: New way to treat heart failure?

Researchers at Michigan Medicine found that activated vitamin D treatments can prevent heart muscle cells from growing bigger and reduce contractions associated with heart failure. The study's results suggest a new way to treat heart failure and provide hope for people affected by the condition.

Moores UCSD Cancer Center study links vitamin D, type 1 diabetes

A recent study by Moores UCSD Cancer Center researchers found that populations living near the equator have lower incidence rates of type 1 diabetes, suggesting a strong role for vitamin D in reducing disease risks. The study's findings support the concept of using vitamin D to prevent childhood type 1 diabetes.

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Low vitamin D levels appear common in healthy children

A study of 380 healthy children found that nearly half had low vitamin D levels, and about one-third showed reduced bone mineral content on X-rays. The researchers suggest that all young children should receive vitamin D supplements to prevent potential health issues.

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Vitamin D protects cells from stress that can lead to cancer

Researchers found that vitamin D increases expression of a key enzyme, protecting prostate cells from damage and injuries leading to cancer. Vitamin D also reduces reactive oxygen species, which can damage DNA and play a role in aging or causing cancer.

Vitamin D in brain function

Scientists at Children's Hospital & Research Center Oakland conclude that vitamin D plays an important role in brain development and function. While the exact effects on behavior remain unclear, evidence suggests a beneficial role for vitamin D in protecting against autoimmune diseases and some forms of cancer.

Vitamin D and breast cancer risk

A study of 1,394 women found that those with low vitamin D levels had a significantly increased breast cancer risk. Carriers of certain polymorphisms in the vitamin D receptor gene also showed an increased risk of developing breast tumors.

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Variants of vitamin D receptor linked to increased risk of breast cancer

A study found that genetic variations in the vitamin D receptor gene are associated with an increased risk of estrogen receptor-positive breast cancer in postmenopausal women. Vitamin D has been shown to play a role in preventing cancer, but its effects on specific genetic variants and breast cancer risk were unclear until this research.

Cancer prevention: stopping cancer before it can start

Researchers present data on the preventive effects of celecoxib and atorvastatin in colorectal, prostate and breast cancer. The study found that patients taking celecoxib had a significant reduction in adenomas, precursor to colon cancer, with low cardiovascular risk. A combination of atorvastatin and celecoxib also inhibited the growt...

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Story ideas from the Journal of Lipid Research

Researchers found that bile acid derivatives can activate the vitamin D receptor without causing calcium buildup, suggesting a new therapeutic direction. Additionally, overexpressing lipoprotein lipase in mice improved their tolerance to cold temperatures by increasing muscular thermogenesis.

Extra vitamin D in early childhood cuts adult diabetes risk

A systematic review and meta-analysis found that vitamin D supplements in early childhood lower the risk of developing type 1 diabetes by around 30%. Higher doses and more regular supplementation were associated with a greater reduction in risk.

Study shows effects of vitamin D and skin's physiology

Researchers from Boston University School of Medicine found that previtamin D3 production varies depending on skin type and weather conditions. Vitamin D deficiency is common worldwide, with increased risk of cancers and autoimmune diseases associated with higher altitudes.

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Drinking milk may help ease the pressure

A new study suggests that drinking fat-free milk may offer protection against hypertension in women. Women who consumed more low-fat milk and had diets higher in calcium and vitamin D from foods tended to have a lower risk for developing high blood pressure.

Lack of vitamin D may increase heart disease risk

A study of 1,739 participants found that vitamin D levels below 15 ng/mL were associated with a twice higher risk of cardiovascular events. Researchers also observed an increase in cardiovascular risk with each level of vitamin D deficiency.

More sun exposure may be good for some people

A new study finds that moderate sun exposure can increase vitamin D production, which protects against various cancers and diseases. The research suggests that people in southern latitudes produce more vitamin D due to increased solar radiation intensity.

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Tip sheet, Annals of Internal Medicine, Dec. 18, 2007, issue

The American College of Physicians has issued new clinical guidelines that recommend against routine screening for carotid artery stenosis. Meanwhile, the use of vitamin D as a standard treatment for chronic kidney disease remains unchanged despite concerns over its effectiveness. Additionally, experts have called for revisions to orga...