Articles tagged with Vitamin D
Researchers found that bile acid derivatives can activate the vitamin D receptor without causing calcium buildup, suggesting a new therapeutic direction. Additionally, overexpressing lipoprotein lipase in mice improved their tolerance to cold temperatures by increasing muscular thermogenesis.
A systematic review and meta-analysis found that vitamin D supplements in early childhood lower the risk of developing type 1 diabetes by around 30%. Higher doses and more regular supplementation were associated with a greater reduction in risk.
A new study suggests that drinking fat-free milk may offer protection against hypertension in women. Women who consumed more low-fat milk and had diets higher in calcium and vitamin D from foods tended to have a lower risk for developing high blood pressure.
Researchers from Boston University School of Medicine found that previtamin D3 production varies depending on skin type and weather conditions. Vitamin D deficiency is common worldwide, with increased risk of cancers and autoimmune diseases associated with higher altitudes.
A year-long clinical trial found that vitamin D2 supplements reduced the risk of falls by 19% among women with low blood vitamin D levels and a history of falling. The therapy was most effective in reducing the risk of single falls during winter and spring, but not multiple falls.
A new study finds that moderate sun exposure can increase vitamin D production, which protects against various cancers and diseases. The research suggests that people in southern latitudes produce more vitamin D due to increased solar radiation intensity.
A study of 1,739 participants found that vitamin D levels below 15 ng/mL were associated with a twice higher risk of cardiovascular events. Researchers also observed an increase in cardiovascular risk with each level of vitamin D deficiency.
Researchers found that vitamin D2 is equally effective as vitamin D3 in maintaining 25-hydroxyvitamin D status, especially in people with vitamin D deficiency. The study showed similar increases in serum 25-hydroxyvitamin D levels for both vitamin D2 and D3.
The American College of Physicians has issued new clinical guidelines that recommend against routine screening for carotid artery stenosis. Meanwhile, the use of vitamin D as a standard treatment for chronic kidney disease remains unchanged despite concerns over its effectiveness. Additionally, experts have called for revisions to orga...
Researchers found a 500,000-year-old human fossil in Turkey with evidence of Leptomeningitis tuberculosa, a form of brain tuberculosis. The discovery suggests that dark-skinned people migrating from low latitudes may be more vulnerable to the disease due to vitamin D deficiency.
A recent genetic study found that higher vitamin D levels are linked to improved genetic measures of lifelong aging and chronic stress. Vitamin D may also play a role in reducing the risk of heart disease and certain cancers.
A study published in the Journal of the National Cancer Institute found no correlation between vitamin D levels and overall cancer death rates. However, elevated vitamin D levels were linked to a significant decrease in colorectal cancer mortality rates.
A study found that increased sunlight exposure reduces the risk of advanced breast cancer in women with light skin color. The researchers measured skin color and compared sun exposure between women with breast cancer and those without, finding a significant difference.
A recent study led by the University of Pittsburgh Graduate School of Public Health found that low vitamin D levels are associated with a higher risk of hip fractures in women. The study analyzed data from 400 women who experienced hip fractures and found that those with lower vitamin D levels had a 77% increased risk.
A meta-analysis of 18 studies found that vitamin D supplements may reduce the risk of death from any cause by 7% over an average six-year follow-up period. Higher blood levels of vitamin D were also associated with a lower risk of death.
A study from the University of Pittsburgh Schools of the Health Sciences found that maternal vitamin D deficiency early in pregnancy is associated with a five-fold increased risk of preeclampsia. Low vitamin D levels also affect newborns, increasing their risk of mortality.
A meta-analysis of 17 studies found that calcium supplementation reduced fracture risk by 24% in individuals with high compliance rates. Vitamin D supplementation also showed significant benefits, with a 16% reduction in bone loss at the spine.
A study found that increasing vitamin D levels can prevent 250,000 cases of colorectal cancer and 350,000 cases of breast cancer worldwide. Researchers recommend optimal vitamin D serum levels to be around 24-32 nanograms per milliliter for prevention.
Researchers at Queen's University have made a groundbreaking discovery about the breakdown of vitamin D, revealing that changing a single amino acid in the hydroxylase enzyme can alter its pathway. This finding has significant implications for the treatment of cancer and other diseases associated with vitamin D deficiency.
A study by Dr. Michael Holick reveals that vitamin D deficiency is common and problematic, increasing the risk of chronic diseases such as osteopenia, osteoporosis, and certain cancers. The author suggests increasing recommended Adequate Intakes for vitamin D to 800-1000 IU/d.
A combination of calcium and vitamin D found in milk may offer protection against type 2 diabetes, with a 15% lower risk among individuals consuming the most dairy. Additionally, magnesium intake from milk products may also reduce type 2 diabetes risk by 15%.
A study of 382 healthy children revealed that over half had low blood levels of vitamin D, with 55% having inadequate levels. Vitamin D deficiency may contribute to bone diseases like rickets and other health issues.
A new study suggests that increasing calcium and vitamin D intake can lower the risk of breast, colon, lung, and other cancers in women. The four-year clinical trial found a significant protective effect with a 77% reduced risk for those taking calcium and vitamin D.
Researchers found that increased body fat in elderly adults is associated with lower levels of vitamin D, regardless of sunlight exposure. Vitamin D is critical for maintaining bone health and low levels can increase the risk of bone fractures and osteoporosis.
Research found that higher intakes of calcium and vitamin D in premenopausal women were associated with a lower risk of developing breast cancer. The study also suggested that the antioxidant effects of these nutrients may be linked to reduced tumor growth in younger women.
A single dose of vitamin D can enhance immunity to mycobacteria, the bacteria that cause TB. The supplement is cheap and effective, with a potential impact on preventing reactivation of latent TB.
A study found that higher dietary intake of omega-3 fatty acids and fish consumption may reduce the risk of advanced age-related macular degeneration. Vitamin D levels were also inversely associated with early stages of the disease, suggesting a potential protective effect.
A large-scale study found that calcium and vitamin D supplements can slow weight gain in postmenopausal women. The benefits are most pronounced in those who weren't already meeting the daily recommended amount of calcium.
A study of 232 older adults found a positive association between high calcium and vitamin D intake and increased brain lesion volume, which can lead to cognitive decline, depression, and stroke. The researchers controlled for age, hypertension, and other factors but found no influence on the relationship.
Older adults with low vitamin D levels are at increased risk for poor physical performance and disability. The study found a significant relationship between low vitamin D levels and poorer physical performance, with results holding true even after adjusting for other variables.
A study by Haojie Li and colleagues found that vitamin D deficiency is common among US men, affecting prostate cancer risk. Genetic variations in the VDR gene are also associated with an increased risk of developing prostate cancer.
A study found that vitamin D insufficiency is prevalent among pregnant women, particularly in northern latitudes and darker-skinned individuals. Vitamin D stores are largely reliant on maternal vitamin D status, highlighting the need for improved public health measures.
Researchers at Université Laval found that taking calcium and vitamin D supplements while on a low-calorie diet reduces the risk of cardiovascular disease. The study, which lasted 15 weeks, showed significant drops in LDL cholesterol and increases in HDL cholesterol.
Researchers at Harvard School of Public Health found an association between higher vitamin D levels and a lower risk of developing multiple sclerosis. The study suggests that increasing vitamin D levels may prevent many cases of MS, with benefits potentially extending to preventing osteoporosis.
Research suggests a strong association between higher circulating vitamin D levels and reduced risk of multiple sclerosis among white individuals. The study found a significant decrease in MS risk with increasing 25-hydroxyvitamin D levels, especially among those measured before age 20.
Scientists have found a way to create smooth muscle cells from adult stem cells using the soluble factors TGF-beta and PDGFB. This breakthrough could lead to new treatments for heart disease by allowing for the creation of healthy tissue. Additionally, researchers have discovered that regulatory T cell populations are impaired in indiv...
Researchers found lower vitamin D levels in women with advanced breast cancer compared to those in early stages. The study supports the idea that vitamin D may play a role in preventing breast cancer progression.
A global study has shown a clear association between kidney cancer incidence rates and proximity to the equator, suggesting that UVB exposure triggers vitamin D production. Countries near the equator have lower kidney cancer rates, while those farther away have higher rates, indicating a potential protective effect of sunlight exposure.
Researchers analyze cases of vitamin D deficiency in UK and conclude that supplementing Asian children for two years from birth can curb re-emergence of the deficiency. Vitamin D deficiency is linked to various health problems, including rickets, poor tooth formation, and increased risk of multiple sclerosis and cardiovascular disease.
Significant studies presented at the World Congress on Osteoporosis highlight the importance of calcium, vitamin D, and protein in building bones, as well as the impact of space travel, obesity, and smoking on bone health. The congress also emphasized the need for improved screening and treatment options for osteoporosis patients.
The study found a reduced risk of breast cancer among women taking calcium and vitamin D supplements, with a significant interaction between those using supplements and those not. The researchers suggest further analysis of vitamin D metabolites may help clarify the findings.
A new study reveals that dietary calcium is more beneficial than supplements alone for building strong bones. Vitamin D supplements only reduce fracture risk when combined with sufficient calcium levels. Meanwhile, research suggests high protein intake promotes bone health.
Research suggests that infant bone growth and maternal vitamin D levels during pregnancy have a significant impact on future fracture risk. Children born to mothers with lower vitamin D levels tend to have weaker bones, while higher levels may improve bone density.
A study of 2,112 adolescents found that low dietary intake of vitamin D is associated with significantly lower lung function. The researchers recommend promoting recommended levels of vitamin D intake to ensure optimal lung function and healthy bones.
Researchers found that SXR inhibits VDR-mediated CYP24 activity in mice, contradicting previous studies. In humans, rifampicin treatment increases CYP3A4 expression but has no effect on CYP24 expression, suggesting a complex regulatory mechanism.
Researchers found that the steroid and xenobiotic receptor (SXR) negatively regulates CYP24 expression and subsequent vitamin D breakdown, but can also enhance vitamin D hydroxylation and breakdown by inducing CYP3A4. Additionally, IL-15 administration restored CD4+ T cell production in an animal model of HIV infection, while lithium w...
A new study suggests that drinking the recommended amount of milk during pregnancy may help increase birth weight. The Canadian researchers found that women who limited their milk intake to one cup or less per day gave birth to babies with lower birth weights compared to those who consumed more milk.
A study found that low milk consumption during pregnancy is associated with lower birth weights. Vitamin D intakes also correlate with infant birth weights independently of other factors. This suggests a potential role for vitamin D in fetal skeletal and neurodevelopmental formation.
Researchers found that higher vitamin D levels were associated with a significant reduction in total cancer incidence and mortality, as well as specific types of digestive system cancers. Daily supplementation with at least 1500 IU of vitamin D may be required to optimize benefits on cancer risk.
Scientists discover that vitamin D can regulate an oncogenic protein called beta-catenin, which is involved in colon cancer development. A drug mimic of vitamin D could potentially prevent some cancers at early stages, but may not be effective for late-stage cancers.
Research reveals a novel pathway involving vitamin D that helps human macrophages kill TB bacilli, explaining why people of African descent are more vulnerable to the disease. Vitamin D levels vary significantly among populations due to melanin's impact on UV light absorption.
The study found a small but significant increase in hip bone density among women taking calcium combined with vitamin D, as well as a reduced risk of hip fractures. However, the benefits were more pronounced in women who were most compliant with supplement dosing and those over 60 years old.
Researchers found a 12% reduction in hip fractures among women taking supplements, but only those who adhered to the full dosage saw benefits. Women over 50 should prioritize dietary sources of calcium and Vitamin D for bone health.
The study found a small but significant increase in hip bone density among women taking calcium combined with vitamin D. However, the supplements had no detectable effect on colorectal cancer incidence or spine fractures.
Researchers discovered that vitamin D significantly limits the ability of prostate cancer cells to invade healthy cells by reducing two key enzymes. Vitamin D also increases counterpart enzymes that inhibit these proteases, leading to reduced cancer progression.
Researchers have identified vitamin D as a potential target for preventing bone loss and osteoporosis. The study suggests that vitamin D may signal anti-osteoclastogenic action, which could lead to new treatments for this condition.
Research suggests that maternal vitamin D status during pregnancy influences bone growth and risk of osteoporosis in offspring. Studies have found that women who took vitamin D supplements or were exposed to higher levels of sunlight during pregnancy had fewer deficiencies and lower risk of osteoporosis in their children.
UCSD researchers found a strong association between vitamin D deficiency and higher rates of colon, breast, and ovarian cancers. They recommend increasing the public's intake of vitamin D3 to 1,000 IU/day to reduce cancer incidence, which could lead to thousands of premature deaths annually.
A study of 2,310 healthy Icelandic adults found that vitamin D status was more important than high calcium intake for maintaining optimal serum parathyroid hormone levels. Vitamin D sufficiency ensured ideal serum PTH values even with low calcium intake, while high calcium intake was not sufficient without adequate vitamin D status.
Researchers discovered that calcitriol and QW-1624-F2-2 slowed prostate cancer progression in intact mice after 14 weeks of treatment, reducing tumor burden. However, chronic treatment showed side effects, highlighting the need for further studies to understand how these agents prevent prostate cancer.