Articles tagged with Cell Growth
Researchers discovered that 3,3'-diindolylmethane (DIM) inhibits the proliferation of human prostate cancer cells by acting as a powerful anti-androgen. DIM, found in cruciferous vegetables like broccoli, decreases PSA levels and blocks the effects of androgen on cancer cells.
Researchers at Whitehead Institute for Biomedical Research have discovered a protein called GβL that helps regulate the mTOR pathway. The study reveals that when GβL is absent or disabled, cells become insensitive to nutrient levels and grow abnormally, which may be a cause of disease.
Conlon and Raff's study found that mammalian cells do not use cell-size checkpoints to determine when to divide, unlike yeast cells. Instead, they rely on extracellular signalling from other cells to coordinate growth and division.
Researchers are investigating new methods to combat cancer growth through computer models and cytotoxic treatments. They also discovered that a process called Auger emission can cause electrons to be emitted in well-defined directions by single molecules, leading to potential breakthroughs in physics research.
Researchers used titanium mesh and bone marrow cells to promote new bone growth in rats, achieving better results with fibronectin-coated mesh and a flow perfusion system. The study presents an alternative method for treating bone defects and highlights the potential for improving cell growth and bone mineralization.
Scientists at Thomas Jefferson University found that a bacterial toxin opens a cellular door, allowing calcium to flow into tumor cells, which slows cell division and may lead to new methods of treating colorectal cancer. The discovery could also enable the use of the toxin as an intravenous infusion to treat metastatic tumors.
Researchers investigate how simple plants like moss grow when deprived of gravity, exploring the role of light and internal forces. The study aims to understand the cellular mechanisms guiding plant growth and development in space.
A new study published in Obstetrics and Gynecology found that aspirin inhibited ovarian tumor cell growth by as much as 68 percent. Combining aspirin with a monoclonal antibody targeting the HER-2/neu protein resulted in an even greater suppression of growth, decreasing cancer cell growth by 84 percent.
Researchers discovered that bone marrow cells can form new blood vessels in newborns, contrary to previous belief that this process only occurs before birth. The study also found that VEGF accelerates the formation of new blood vessels, with implications for tumor biology and congenital disorders.
Researchers at University College London have discovered a potential new cancer treatment using compounds found in cola beverages, coffee, tea, and chocolate. The compounds block the operation of a key enzyme linked to cell growth and blood clotting.
Researchers John Tyson and Bela Novak are developing mathematical models of yeast cell growth and division to better understand the molecular mechanisms controlling cell behavior. Their work aims to extrapolate findings from yeast cells to humans, with potential implications for cancer research and other cell-based diseases.
Researchers identify DHH as key player in fetal Leydig cell differentiation, enabling testosterone production. The discovery provides insights into human reproductive disorders resulting from faulty sex determination pathways.
Researchers at Vanderbilt University Medical Center have identified a key signaling pathway involved in the development of precancerous polyps. The study found that blocking this pathway can prevent polyp formation and potentially colon cancer. By understanding how this pathway works, scientists hope to develop targeted treatments.
A team of researchers at the University of Pittsburgh has discovered a gene mutation responsible for hereditary gingival fibromatosis (HGF), a rare condition characterized by gum overgrowth. The discovery may lead to new therapies, including tissue engineering, and could have implications for treating common dental problems like period...
The researchers aim to create a prototype for real-time measurement of complex processes within cells. This technology could lead to more effective drugs and insights into human disease.
A study of 38 children with sickle cell disease found that zinc supplementation significantly increased rates of growth in height and sitting height after 12 months. The treatment reversed growth deficits and delayed development, unlike the control group which showed gradual growth failure characteristic of SCD.
Researchers at The Wistar Institute have identified a carefully orchestrated series of molecular modifications to p53 that must occur for it to perform its normal function. This discovery may suggest new ways to combat cancers where p53 is dysfunctional, and could also provide insights into the regulation of other DNA-binding proteins.
Researchers discovered a natural protein called p22 that inhibits blood vessel growth, preventing tumors from growing. The study showed that p22 is released by cancerous cells and targets only those cells that help tumors grow, reducing the risk of metastasis.
Researchers discover bacterial toxin ST can slow down metastatic colorectal cancer tumor growth by targeting GCC receptor. GCC is a protein marker on cancer cells that allows scientists to detect if they have spread, and it can also be used as a diagnostic tool.
Researchers at Ohio State University are investigating ways to re-grow tiny blood vessels to keep damaged heart tissue alive after a heart attack. They have demonstrated that endothelial cells can grow in grooves carved in the surface of a soft transparent gel in the laboratory, paving the way for future transplants.
Researchers at Cornell University have discovered how a hyperactive form of the molecular switch Cdc42 disrupts orderly cell growth, leading to cancer. The team found that Cdc42 increases protein shuttling, overstimulating cellular activities and causing hallmarks of cancer cells.
Researchers at Fred Hutchinson Cancer Center discovered a protein, Rrn3, that regulates cell growth in both humans and yeast. The protein appears to be a key player in an as-yet-unidentified cell-signaling pathway, potentially making it a unique drug target for cancer treatment.
Researchers have successfully engineered cancer cells that can suppress growth at secondary sites, a breakthrough with implications for the treatment of cancers that metastasize. By inhibiting cell growth at the site of metastasis, these cells may be able to treat existing tumors by blocking their ability to grow.
Researchers at the University of Illinois Chicago found a common genetic link between diverse age-related diseases, including cancer and Alzheimer's disease. The activation of the p21 gene may contribute to the development of these diseases by stopping cells from growing and dividing.
Researchers successfully differentiated human placental cells by adjusting gap size in a fibrous-bed bioreactor, mimicking the body's natural process. The breakthrough may aid organ production for transplantation and has implications for tissue engineering and cancer research.
A University of North Carolina Health Care study led by Lee Graves clarifies how cells grow and suggests new drug targets for cancer cells. The research focuses on the MAP kinase enzyme and its role in regulating cell growth.
Scientists have discovered that the myc gene is even more powerful than previously believed, controlling cell growth and division while disabling brakes on growth. The findings mark a significant step towards understanding how faulty cell signals lead to cancer.
Sulindac has been shown to cause the regression of benign colon polyps, helping prevent colon cancer development. The drug inhibits cancer cell growth by promoting programmed cell death and preventing NF-kB activation.
Scientists at Emory University discovered a new family of enzymes linked to abnormal cell growth in cancer and cardiovascular disease. The Mox1 enzyme converts oxygen into reactive oxygen molecules that instruct cells to divide more rapidly.
The University of Iowa is conducting a space shuttle experiment to study human cell growth and metabolism in space. The oxygen-sensing system developed by the university will be used to monitor oxygen levels and provide feedback control for optimal growth conditions.
Researchers find potential anti-cancer agents in ethanol extract of soybean molasses from crop-processing plant waste. The active compound, phytochemical complex 100 (PCC 100), contains saponins and suppresses cancer cell growth, reducing human colon cancer rates.
A University of Michigan team discovered that vascular endothelial growth factor (VEGF) helps blood vessels survive and proliferate in the face of nutrient depletion. This mechanism is thought to support tumor growth, leading researchers to explore strategies for inhibiting VEGF to starve tumors.
Physicians at the University of Chicago Medical Center have found a way to bring full immune system power against cancer using co-stimulation technology. Patients with advanced or recurrent lymphoma have experienced anti-tumor effects and complete remissions after receiving expanded, co-stimulated T cells.
Scientists are using NASA Bioreactors to culture breast cells on Earth, learning what controls their growth and how to thwart malignancies. The research has the potential to improve healthcare for women, including those traveling to Mars, by developing new therapies that target cancer's genetic weaknesses.
Researchers have discovered a molecular circuit breaker that prevents uncontrolled cell growth, which could increase the effectiveness of conventional anti-cancer therapy. The protein ARF works as a fuse or circuit breaker, monitoring cell signals and preventing over-stimulation.
Cornell University researchers found that retinoic acid reverses the growth-promoting effects of oncogenes, which induce cancer. The study suggests enhanced therapies for leukemia and highlights the cancer-prevention role of carotenes in a diet rich in yellow-orange vegetables.
Researchers grew viable cartilage tissue from bovine cells on polymer scaffolds, but found that tissues grown in space were smaller and mechanically weaker than those on Earth. This study demonstrates the feasibility of cultivating cells and tissues in space over long periods.
Cancerous cells produce high amounts of free-radicals that promote uncontrolled cell growth; antioxidants and protein inhibitors can suppress this process, slowing down runaway cell division.