Articles tagged with Cell Viability
A new study found that inducing mitochondrial reactive oxygen species (ROS) during embryonic development protects the adult heart from chemotherapy toxicity in mice. The study discovered that stressed mitochondria release citrate, leading to long-term epigenetic changes that promote beneficial mitohormetic adaptations. These findings s...
A recent review of bamboo consumption found promising health benefits, including improved metabolic health, reduced inflammation, and antioxidant activity. However, caution is advised due to potential risks associated with raw or improperly prepared bamboo.
Researchers developed three new two-photon probes that can visualize organelles in cells, enabling better understanding of cellular functions and tissue imaging. The probes are designed to detect pH levels, viscosity, and ionic species, providing more specific insights into cell viability and treatment responses.
Researchers investigated the roles of STAT3α and STAT3β in aggressive breast cancer and found that differential silencing of these isoforms leads to changes in STAT3 activation. This study emphasizes the importance of distinguishing between STAT3 isoforms for accurate cancer diagnosis and therapy.
Researchers found that glutaminase inhibitor BPTES selectively eliminates senescent dermal fibroblasts, improving skin aging phenotype by increasing collagen density and cell proliferation. The study suggests BPTES as a potential therapeutic agent for skin aging, offering new treatment options.
Researchers at NC State University have developed a reproducible method for studying cellular communication in plant cells using 3D bioprinting. The study found that more than half of the bioprinted cells were viable and divided over time, with soybean embryonic cells remaining viable for two weeks after bioprinting.
Researchers discovered that vitamin K acts as an antioxidant, inhibiting ferroptotic cell death and identifying FSP1 as the warfarin-insensitive enzyme responsible. This finding has implications for treating Alzheimer's disease and acute organ injuries.
Researchers identified CUDC907 as a dual phosphoinositide-3 kinase/histone deacetylase inhibitor that promotes apoptosis in NF2 schwannoma cells. The compound reduced viability and induced cell cycle arrest in human merlin deficient Schwann cell models.
Researchers have found a new approach to treat cancer by using plasma treatment, which induces apoptosis in cancer cells without harming normal cells. The equivalent total oxidation potential (ETOP) has been defined as a plasma dose, providing a dose-response relationship for different cell types.
The University of Houston research team has successfully developed a method for 3D printing organic semiconductor devices using multiphoton lithography, enabling the creation of highly conductive microstructures. The technology has potential applications in emerging fields such as nanoelectronics and bioelectronics.
Researchers found that frozen testicular tissue from rats can be reimplanted and produce viable sperm after over 20 years, but with reduced fertility. The study has important implications for treatment of boys with cancer and may provide a method to recover lost fertility.
Researchers developed a digital subtraction technique to identify viral DNA in tumor samples, achieving comparable results to standard clinical methods. The study discovered novel associations between specific tumors and viruses, warranting further investigation.
A new imaging method, combining optimal imaging and machine learning, can determine cell viability without chemical staining. The approach achieved a 95% accuracy rate and has the potential to be applied in hospitals and research labs.
Researchers have created a new approach to edit genes within specific bacteria in a community using CRISPR-Cas9, enabling targeted genetic modifications. This technology could be used to track edited microbes and potentially treat diseases like digestive issues or create more resilient crops.
Scientists from the University of Johannesburg found that shining two lasers on adult stem cells accelerates their transformation into different types of cells. The consecutive irradiation increases proliferation and differentiation under laboratory conditions, paving the way for potential therapies to repair damaged tissues.
Scientists from Nara Institute of Science and Technology have created a simple and fast method for detecting cell shape as they pass through a microfluidic channel. The team used changes in electrical impedance to measure the asymmetry of individual cells, which may greatly accelerate biological experiments.
Researchers have successfully grown cells from stony coral Acropora tenuis, creating eight distinct cell types that can grow indefinitely. The cell lines hold promise for understanding coral interactions with photosynthesizing algae and bleaching processes.
Researchers at Toyohashi University of Technology developed a low-cost method for intracellular delivery using titanium-oxide nanotubes and nanosecond pulse lasers. The study successfully delivered propidium iodide and fluorescent dextran into HeLa cells with high efficiency and cell viability.
Researchers developed a new method combining label-free imaging with artificial intelligence to study live cells over time. The technique allows for the estimation of cell attributes without using toxic fluorescent dyes.
A new study overturns the classic theory that single-celled organisms can only evolve to become multicellular life forms if doing so increases their overall productivity. The model suggests that cell specialization can be favored even if it reduces group productivity, contradicting the prevailing view.
A microrobot combined with in situ, in vivo bioprinting has been developed to treat gastric wounds. The platform, which can fold itself down to enter the body, has shown promising results in repairing tissues and promoting cell viability.
Researchers at NYU Abu Dhabi have developed a new technique to preserve human cells using filter paper, offering advantages over traditional methods. The method requires less storage space and allows for easy loading and efficient freezing of cells, with viability rates comparable to conventional methods.
Researchers at SUTD have developed an acoustic fluorescence activated cell sorting (aFACS) system that isolates cells with high purity and viability. The system uses elasto-inertial particle focusing to improve sorting accuracy and efficiency, resulting in minimal cell damage and high recovery rates.
Researchers found that overwintering Microcystis cells in sediments can seed the next year's bloom, explaining the rapid increase in Lake Erie bloom size and spatial extent. The study advances scientists' understanding of the basic biology driving the annual summer blooms.
Researchers developed a model that explains how cell specialization arises in response to resource constraints. The model considers the influence of environmental factors and initial differentiation of cells, providing a more realistic understanding of cellular specialization.
Researchers at Nagoya University have created a high-speed cell sorting method that can sort large cells with high viability, purity and success rates. The technique uses microfluidic chip-based dual on-chip pumps to control flow, enabling rapid sorting of both small and large cells.
Researchers develop rhodanine-based compounds to solubilize poorly water-soluble drugs, inhibiting tau protein aggregation and improving cell viability. The formulation additives preserve drug efficacy and activity, offering opportunities for early-stage drug testing.
Nader Pourmand's nanopipette technology wins $300,000 prize in NIH 'Follow that Cell' challenge, enabling repeated analysis of individual cells without disrupting their activity. The platform has vast potential applications, particularly in cancer and neurodegenerative disease research.
The Rutgers team has developed a microfluidic platform that detects membrane permeabilization in cells exposed to electric fields, allowing for efficient delivery of biomolecules. The technology improves transfection efficiency and cell viability, enabling the study and engineering of fundamental cellular processes.
Researchers have developed artificial cells that use enzymes to move like real cells, maintaining homeostasis like living cells. The lab-made cells can sustain speed based on sugar supply availability.
Researchers found that certain electronic cigarette flavors can alter important cellular functions in lung tissue, including changes in cell viability, proliferation, and calcium signaling. Flavors such as Hot Cinnamon Candies, Banana Pudding (Southern Style), and Menthol Tobacco were shown to be toxic to cells at higher doses.
Researchers discovered that fruit flies can develop and be fertile in the absence of histone H3.3, challenging established models of gene regulation. Additionally, they found that histone modification is not essential for activating genes, but rather plays a role in regulating their expression.
Researchers from Nagoya University used a micro putter to test the adhesion of yeast cells on various surfaces. They found that dead cells stuck less than living cells, supporting the 'cell adhesion model'. This study could lead to new methods for evaluating cell health and developing effective treatments.
A Syracuse University research team has created a temperature-sensitive shape memory polymer substrate that can change shape under cell-compatible conditions. The breakthrough, led by James Henderson and Kevin Davis, offers potential solutions for current limitations of static substrate research in bioengineering.
A pioneering study shows tissue-engineered urethras, made with the boys' own cells, are functional and viable within 3 months. The grafts have lasted at least six years and maintained adequate outflow, offering a new alternative for reconstruction.
Researchers discovered that low-intensity ultrasound therapy can improve the survival and function of tissue grafts after surgery. The treatment increased cellular activity, reduced waste buildup, and enhanced molecular motion, leading to better outcomes for patients undergoing various surgical procedures.
Scientists at UC San Diego discovered the gene responsible for this effect, which prevents cellular damage from reactive oxygen species. The study found that Mga2 is essential for adaptation to oxidative stress and may explain why caloric restriction can raise ROS levels and provide protection.
A study investigates the impact of femtosecond laser-induced damages on olfactory ensheathing cells, revealing that cellular activity can be controlled easily. The research suggests four reasons for the formation of femtosecond laser-induced calcium waves and proposes cell damage and recovery mechanisms.
Researchers found that high-dose statins can decrease satellite cell proliferation, potentially affecting muscle healing and repair. The study's findings suggest a need for further research on the effects of statins on muscle progenitor cells in older adults.
Researchers have developed reliable methods to assess the concentration and viability of anthrax spores after prolonged storage using DNA analysis techniques. This study provides essential steps in developing a reliable reference standard for anthrax detection and decontamination.
A Yale University study reveals that high levels of testosterone can lead to programmed cell death in nerve cells, associated with conditions like Alzheimer's disease. Elevated testosterone also triggers behavioral changes such as hyperexcitability and suicidal tendencies.
Research suggests that GLP-1 can generate new insulin and increase the growth of new islet cells in human pancreas tissue. This treatment delayed cell death by up to 45% and improved insulin secretion in response to glucose, offering a potential therapeutic approach for Type 2 diabetes.