Articles tagged with Neuroblasts
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers found that removing the choroid plexus leads to a reduction of newly born immature neurons and fewer repairing damage caused by a stroke. The study suggests that the choroid plexus keeps regenerative cells ready to deploy to injured areas in animal models.
Researchers found that removing the choroid plexus led to a reduction in newly born immature neurons, which are essential for repairing damage caused by stroke. The study suggests that the choroid plexus may be necessary to retain these cells and facilitate brain repair after injury.
A study investigated the association between miR-492 rs2289030 G>C polymorphism and neuroblastoma susceptibility in Chinese children. The results showed no significant impact of the polymorphism on neuroblastoma risk, suggesting a need for further validation with larger samples.
The study reveals that non-coding regions near sloppy-paired genes are essential for temporal transcription factor expression and that Notch-signaling regulates the transition to subsequent TTFs. This mechanism couples temporal patterning with neuron generation, providing insights into brain diversity.
In a study published in Nature Communications, researchers uncovered the molecular players involved and how timing is controlled for creating neural diversity. Single-cell RNA sequencing technology revealed a temporal patterning gene network in Drosophila medulla neuroblasts, including nine new transcription factors.
A study by Makoto Sato and colleagues from Kanazawa University reveals that a gene called Dscam regulates the repulsion between neurons in fly brains, leading to the formation of columnar structures. This finding supports the radial unit hypothesis, which describes the development of the cerebral cortex in mammals.
Researchers at Baylor College of Medicine discovered that the Zika virus protein NS4A disrupts brain growth by hijacking a pathway that regulates the generation of new neurons. The study found that overexpression of Zika protein NS4A causes microcephaly in flies by inhibiting the function of ANKLE2, a cell cycle regulator.
Researchers have identified a novel mechanism for neuronal regeneration after stroke. By overproducing the protein Slit in neuroblasts, these cells can migrate past activated astrocytes and mature into functional neurons.
Research reveals that fruit flies' adult and larval nervous systems share similar structures and molecular signatures, contradicting the traditional view of metamorphosis as two separate stages. The study uses lineage tracing to identify neuroblast lineages and discover unique neuroblasts controlling leg motor neurons.
Two protocols from the Neurobiology of Drosophila course are now available in Cold Spring Harbor Protocols: a method for stimulating neurons in the brain and identifying neuroblasts via immunofluorescent staining. These methods provide insight into the giant fiber system and role of stem cells in development.
Researchers found that an enzyme called aurora-A is required to coordinate protein position within neural stem cells, and its absence leads to overproduction of new neuroblasts and tumors. In humans, this enzyme may prevent abnormal tumor growth by maintaining a steady population of stem cells.
Researchers found that neural stem cells migrate to injured brain areas in response to acute brain injuries, such as strokes. This self-repair mechanism could potentially lead to new treatments for brain-related disorders.