Researchers at Ohio State University have created the first DNA gene chip for horses, containing over 3,200 expressed horse genes, allowing for rapid scanning of individual horse genes. This breakthrough could lead to better accuracy in studying human disease and developing new treatments.
Molecular signals play a critical role in separating the lymphatic system from the circulatory system during fetal development. The study sheds light on the mechanisms behind this separation and its potential therapeutic applications, including influencing blood vessel growth and tumor treatment.
Scientists have developed a new, non-invasive method to study neurochemistry and behavior in animal models of neurological and psychiatric diseases. The microPET technique allows researchers to measure dopamine receptor levels in living animals, providing insights into disease progression.
A new model predicts that an animal's body size determines how often it encounters food in its environment. The researchers found that larger animals have bigger home ranges due to their ability to perceive and average over different scales of resource availability.
Researchers have successfully treated metastatic disease using a modified herpesvirus, providing a promising treatment option for patients with advanced cancer. The therapy has shown promise in early trials, demonstrating its potential as a novel approach to combatting this devastating disease.
Researchers use SAGE to study fruitfly genome, identifying genes responsive to JNK signal that help skin form properly and understand its effects on a whole organism
Ecologists developed a new mathematical model that uses just a few factors to capture the essentials of predator-prey battles, predicting population cycles and dynamics. The model was tested in a laboratory microcosm with single-celled algae and microscopic animals, showing results consistent with predictions.
Scientists at NIH and Whitehead Institute have grown malaria parasites in fruit flies, creating a model for studying parasite development in insects. The new model has identified a part of the insect immune system that naturally attacks malaria parasites.
Researchers suggest that early life forms could have emerged from heterogeneous lipid assemblies, with information stored in composition rather than sequence. This model offers a solution to the long-standing question of how lipid assemblies could carry and propagate information.
Scientists have discovered a gene in yeast that plays a key role in regulating the aging process. The SIR2 gene helps slow down aging by silencing certain genes, and its activation can extend the life span of yeast cells. This breakthrough could lead to the development of new anti-aging therapies.
Scientists developed a theoretical model of food web organization based on two simple rules, revealing deep similarities between diverse ecosystems. The 'niche model' accurately predicts 12 characteristics of food webs, surpassing the cascade model's predictions.
Scientists create mouse model to track immature T cells' transformation into specialized killer T cells capable of destroying infected or cancerous cells. The research aims to understand how the immune system thwarts T cell functionality in diseases like HIV and cancer.
A mathematical model of H.pylori bacteria and their human hosts reveals the key role played by adherent bacteria in colonization, as well as the dynamic relationship between host response and bacterial persistence. The model sheds light on the complex interactions between the bacteria and human immune system.
Climate models project a 23-30% decline in mountain snowpack by 2025, and up to 61% by 2095. This could drastically alter hydrology and water resource management in the region.
A team of scientists has created a detailed model of the structure of a protein in photosynthetic bacteria, which can help explain how certain diseases such as Alzheimer's and Mad Cow Disease occur. The model shows how nature uses irregular forms to create complex structures that are effective at absorbing sunlight.
Scientists at Boston University report a new model of ventilator assisted lung function that incorporates 'noise' to improve gas exchange in patients with lung injury. The approach may also minimize additional trauma by enhancing the avalanche-like opening of airways and alveoli during inhalation.
David Meyer presents evidence that ancient crinoid Uintacrinus could float using a new model. The model explains the organism's ability to support its weight and collect food particles at the sea surface.
The Stanford research group synthesized a compound that replicates the chemical wizardry of cytochrome c oxidase, a vital biochemical process found in all oxygen-using organisms. The model converts oxygen molecules into water, releasing energy to charge biological batteries and generate heat.