Articles tagged with Gingiva
Researchers developed a new approach to eliminate pathogenic bacteria like Porphyromonas gingivalis in periodontitis without harming healthy tissue. This therapy preserves beneficial oral microbes, reducing bone loss and improving oral microbiota in mouse models.
New research demonstrates that restoring the physical stiffness of the gingival tissue can fundamentally change how cells respond to infection, potentially paving the way for new treatments. The study uses a hydrogel system to investigate how gum tissue stiffness impacts periodontal disease inflammation.
Researchers developed a powder based on morin, extracted from plants like guava leaves, apple peels, and figs, to combat periodontal disease. The study found that the substance can be slowly released through polymers, providing an alternative to antibiotics for controlling microorganisms.
A new narrow-spectrum antibiotic, FP 100, has been found to effectively eliminate Fusobacterium nucleatum without harming the oral or gut microbiomes. This breakthrough discovery holds significant implications for treating severe gum disease and preventing related systemic conditions such as colon cancer and Alzheimer's disease.
An interdisciplinary team at MUSC Hollings Cancer Center discovered how P. gingivalis interferes with mitophagy, allowing oral cancer tumors to become resistant to chemotherapy. The study identified the role of fimbriae in attaching to specific proteins on the mitophagic membrane, blocking the chemotherapy drug from its attachment point.
Researchers found that matcha mouthwash significantly reduced levels of Porphyromonas gingivalis in saliva samples from people with periodontitis. Matcha's bactericidal activity against the pathogen was confirmed through lab experiments.
Research reveals a significant connection between oral bacteria and accelerated pancreatic cancer development in mice. Viable Porphyromonas gingivalis was found in the pancreas of healthy mice after gum application, causing changes in the organ's microbial balance.
Researchers from Osaka University found that gargling with an antiseptic mouthwash can reduce periodontitis-related bacteria in patients with type 2 diabetes. This simple method may improve the lives of people with periodontitis-linked diseases such as diabetes, dementia, and cardiovascular disease.
Researchers found that bariatric surgery leads to an increase in caries and periodontitis, as well as alterations in salivary inflammatory markers. The study's findings emphasize the importance of dental assessment for patients undergoing bariatric surgery.
A study by Forsyth Institute researchers reveals a link between periodontal disease and amyloid plaque formation in the brain. Oral bacteria can travel to the brain, causing neuroinflammation and promoting cognitive decline in Alzheimer's patients.
A Tohoku University study found that soft gingiva is more likely to cause inflammation, hindering the development of collagen fibers. This discovery has implications for the development of advanced biomaterials and microdevices to control local inflammation.
Researchers found a connection between arthritis flare-ups and periodontitis, suggesting that regular dental check-ups could help prevent rheumatoid arthritis. The study also identified potential therapeutic targets for cancer, including the use of mouthwash to prevent flares.
Researchers led by Osaka University found that Fusobacterium nucleatum produces polyamines through metabolic cross-feeding, creating favorable conditions for periodontal pathogens to grow and spread. This integration of a metabolic network within the oral microbiome may promote the development of periodontitis.
The Chemical Insights Research Institute has received a prestigious award from the National Institutes of Health to study the link between electronic nicotine delivery system (ENDS) usage and periodontal disease. The researchers will analyze consumer vaping behavior data and biosamples to identify biomarkers of exposure and injury, aim...
A new University of Washington study found that bleeding gums on gentle probing and retinal hemorrhaging are associated with low vitamin C levels in the bloodstream. Increasing daily vitamin C intake helped reverse these bleeding issues.
Researchers found that gingival mesenchymal stem cells release more proteins, including IL-1RA, which blocks proinflammatory cytokines, accelerating wound healing in mucosal tissues. The study suggests potential therapeutic applications for delayed wound healing in diabetic patients.
A study explores the relationship between Chédiak-Higashi syndrome and periodontitis, revealing that LYST mutations affect TLRs and lead to a dysregulated immune response. Classic CHS patients with bone marrow transplantation exhibited mild chronic periodontitis, while atypical CHS patients showed no evidence of aggressive periodontitis.
A study found moderate-to-severe gingivitis to be common in pregnant women, particularly among younger mothers. Regular dental care is crucial for maintaining oral health during pregnancy, as gestational age and maternal age were significant factors in gingival bleeding.
A new study by the Ostrow School of Dentistry of USC found that stem cells in gum tissue can relieve inflammatory diseases, including colitis. The cells, called gingival mesenchymal stem cells (GMSC), have the ability to become other cell types and affect the immune system.
During pregnancy, pregnant women can experience significant changes in their oral health, including gingivitis, pregnancy tumors, and mild to severe gingival enlargement. Regular dental check-ups and proper oral hygiene can help alleviate gum inflammation and prevent worsening of conditions.
Scientists have identified genetic mutations on chromosome 17q24.2-q24.3 as responsible for Congenital Generalized Hypertrichosis Terminalis (CGHT), a rare condition characterized by excessive hair growth and facial distortion. The discovery provides new insight into the molecular mechanisms underlying this condition.
A new study published in the Journal of Periodontology found that combining tongue and tooth brushing with dental flossing significantly decreased gingival bleeding by 38 percent after a two-week oral hygiene program. Halitosis was also reduced, with gingival bleeding sites increasing by almost four percent in those who didn't floss.
Researchers found that AAS abusers had statistically significant levels of gingival enlargement compared to non-users, requiring a gingivectomy for many cases. Gingival inflammation was also higher in the user group, suggesting potential long-term effects on periodontal health.
A recent study found that eating sug-free traditional yoghurt can decrease volatile sulfide compounds in the mouth by 80% after six weeks. The results also showed lower plaque and gingival indices in yoghurt-eating volunteers compared to non-yoghurt-eating groups with bad breath.
A study suggests that women undergoing infertility treatment who have periodontal disease may experience higher levels of gingival inflammation and bleeding, which could impact the success of fertility treatments like ovulation induction medication. Maintaining good oral hygiene is crucial to prevent these issues.
Researchers found that gingival inflammation decreases during menstruation compared to ovulation and premenstruation. The hormone estradiol may play a role in this phenomenon, according to the study published by the American Academy of Periodontology.
A team of researchers at the University of Pittsburgh has discovered a gene mutation responsible for hereditary gingival fibromatosis (HGF), a rare condition characterized by gum overgrowth. The discovery may lead to new therapies, including tissue engineering, and could have implications for treating common dental problems like period...
A case report found that oral piercing can cause localized gingival recession, increasing the risk of tooth decay and periodontal disease. Researchers warn of other complications such as infection, swelling, and metal hypersensitivity.
A recent study reveals that children with Down syndrome are susceptible to severe periodontal disease due to factors such as inadequate oral hygiene and congenital deformities. Research suggests that proper plaque control can help ward off the disease, emphasizing the importance of regular dental visits and education for parents.
A study suggests that frequent dental visits can eliminate gingival overgrowth recurrence in patients taking nifedipine for high blood pressure. This regimen significantly reduces gum swelling and associated health risks.