Articles tagged with Kidney
Patients with reduced kidney function and high proteinuria at increased risk of death, heart attacks, or progression to kidney failure. The study suggests that future guidelines for chronic kidney disease classification should incorporate information on proteinuria levels.
Researchers at Vanderbilt University Medical Center have discovered that acetaminophen can prevent oxidative damage and kidney failure after muscle injury in a rat model. The study's findings support further investigation into the drug's effects in patients with severe muscle injuries.
Patients with type 2 diabetes who experience subtle brain damage may be at risk of progressive kidney disease and kidney failure, according to a new study. Diabetic patients with silent cerebral infarction were nearly five times more likely to develop serious kidney disease than those without.
A study found that kidney transplant recipients with high levels of T-regulatory cells and low Natural Killer cells are at a higher risk for skin cancer, which can occur after ten years of immunosuppressive drugs.
A study of nearly 2000 healthy adults found that kidney abnormalities occur in at least 25% of the population. Most abnormalities were mild and not causing discomfort, but future research is needed to determine their impact on long-term health.
A study found that end-of-life care falls short for kidney disease patients, with many lacking adequate support and education. Patients expressed a desire for help planning for the future, pain management, and psychosocial support, but these services were not routinely integrated into their care.
A Johns Hopkins Children's Center study found that even small amounts of lead in healthy children's bodies can impair kidney function, with those having higher levels showing decreased kidney filtration rates. The researchers measured kidney function using two tests and found a link between higher lead levels and worse kidney function ...
Researchers identified a genetic cause of focal segmental glomerulosclerosis (FSGS), a devastating kidney disease that forces children and young adults onto dialysis. The INF2 gene, which regulates actin in podocytes, may hold clues to developing treatments for the disease.
A study published in Journal of the American Society of Nephrology found that patients with acute kidney injury (AKI) who did not require dialysis had a significantly higher risk of death over two years compared to those without AKI. The risk was even higher for patients with more severe AKI and returned to normal after discharge.
A new study finds that West Nile virus can remain in the kidneys of infected individuals for years, potentially causing chronic symptoms and kidney failure. Researchers collected urine samples from patients with severe initial infections and detected viral RNA for at least six years following infection.
A new study reveals that sleep apnea is associated with an increased risk of high blood pressure, heart disease, and stroke in kidney transplant patients. The condition was found to be present in one in four individuals and more than doubled the risk of cardiovascular complications.
A new study by Henry Ford Health reveals that heart failure patients developing kidney dysfunction in the hospital have a poor prognosis, with only 39% experiencing short-lived kidney issues. The research highlights the importance of understanding why kidney dysfunction persists in some patients and finding ways to prevent it.
A team of researchers from Emory University, Children's Healthcare of Atlanta, and Georgia Tech has developed a novel continuous renal replacement therapy device designed specifically for children. The device addresses safety concerns and size limitations associated with adult kidney dialysis equipment, which can lead to dehydration an...
African Americans are less likely to receive kidney/pancreas transplants than similar patients in other racial groups, despite increased Medicare coverage. Physician bias may be a contributing factor, with doctors assuming African Americans have type 2 diabetes when they may actually qualify for type 1 diabetes.
Declining kidney function increases the risk of heart failure and premature death. Treatments that slow kidney function decline may safeguard heart health by stabilizing it in the normal range before kidney disease develops.
Researchers have identified a new molecular pathway and class of molecules that can prevent potassium buildup in the bloodstream, which can cause fatal cardiac arrest. This discovery could lead to the development of new drugs to treat hyperkalemia, a condition affecting 8% of hospitalized patients.
A new study found that switching to a newer type of immunosuppressant drug, sirolimus, reduced the rate of skin cancer in kidney transplant patients by 25%. Nearly half of patients stopped treatment due to side effects. The researchers believe this could offer a new option for reducing skin cancer risk in transplant recipients.
Women with chronic kidney disease are more likely than men to be undiagnosed, according to a new study. The study found that primary care physicians need more education on diagnosing CKD, which could lead to improved patient outcomes and cost savings.
A new study published by the American Society of Nephrology suggests that having a history of lupus does not significantly increase the risk of developing lupus nephritis in recipients of a kidney transplant. The study found that lupus nephritis occurred in just 2.44% of patients, and was associated with only a 7% risk of organ loss.
Researchers found that oral activated charcoal lessens atherosclerotic lesions in experimental mice with kidney damage. This effect appears to be related to reduced inflammation in the blood vessels, regardless of treatment timing or changes in blood pressure or cholesterol levels.
A new study presents evidence that high sodium intake and artificial sweetener consumption are associated with a faster rate of decline in kidney function. The research, conducted by Brigham and Women's Hospital, analyzed data from over 3,000 women participating in the Nurses' Health Study.
A recent study published in the American Society of Nephrology's Annual Meeting and Scientific Exposition found that kidney transplant survival rates vary by donor race, with non-black recipients experiencing lower survival rates when transplanted with black donors.
Recent medical school graduates are more likely to refer CKD patients for preemptive kidney transplantation, which can improve patient outcomes. The study suggests that educating veteran physicians about the benefits of preemptive transplantation may increase early referrals.
Researchers found that patients with higher kidney function at the time of transplant did not have a significant advantage in terms of long-term health. However, they did require less dialysis and were less likely to experience kidney rejection after transplantation.
A study found that kidney transplant consent forms are written at a 12th-grade reading level, but should be prepared at a 5th-8th grade reading level to ensure all patients can provide informed consent. This disparity may lead to unequal access to treatment and health outcomes among different patient populations.
Group education of patients' relatives and friends can improve their willingness to consider kidney donation. The study found that group discussions increased the number of potential donors among participants.
Long-term steroid abuse in bodybuilders led to severe kidney damage, including focal segmental glomerulosclerosis. The condition causes scarring within the kidneys, similar to that seen in morbidly obese patients but with more severe effects.
A study has found that coronary angiography does not harm kidney function in advanced chronic kidney disease patients, enabling better transplant decisions. The test detected coronary artery disease in some patients, making them unsuitable for transplantation until their heart complications were addressed.
Researchers have tested various cell-based therapies in mice with Alport syndrome, a genetic kidney disease. Stem cell treatments may repair kidney defects associated with the disease, offering promise for patients.
Researchers from Stanford University and colleagues have discovered a gene associated with human kidney aging, revealing new insights into the aging process. The study used sequential transcriptional profiling and eQTL mapping to identify genetic variants linked to kidney aging.
A new study suggests that invasive procedures may not be necessary for all patients with narrowed arteries in and around the kidneys. The researchers found that only a small percentage of cases progress to a dangerous blockage, and progression does not always predict severe kidney function decline.
Researchers have developed a reliable way for doctors to filter MEDLINE for relevant kidney patient information, improving treatment and outcomes. The new tool has high performance, exceeding 97% sensitivity and specificity, making it available for all healthcare professionals.
For kidney disease patients, regular physical activity may prolong life and reduce mortality risk. A recent study found that active patients were 56% less likely to die than inactive counterparts.
A new study reveals that kidneys recovered from deceased donors with acute renal failure can function just as well as those from healthy donors, opening up a significant expansion of the donor kidney pool. This could lead to an additional 1,000 kidneys or more per year being made available to patients waiting for a transplant.
A Monash University study has identified the role of microscopic antennas in the kidney's repair process, shedding light on a potentially fatal disease. The research, led by Dr. James Deane, showed how hair-like structures called cilia change their length in response to injury, amplifying signals that turn off the repair process.
A new study links impaired kidney function to faster cognitive decline in older adults, especially in episodic, semantic, and working memory. The researchers found that poor kidney function accelerated cognitive decline equivalent to seven years of age at baseline.
A cohort study of 120 women who gave birth after receiving a kidney transplant found no differences in kidney function or patient survival compared to those who did not have children. The study's findings provide good news for kidney transplant women who fear getting pregnant due to concerns about their health and lifespan.
A study found that childhood minimal change nephrotic syndrome can lead to lasting health effects, including osteoporosis and hypertension in adults. The condition may also cause reproductive problems, such as low sperm count and defective sperm.
A study published by the American Society of Nephrology found that weight loss through diet and exercise can reduce proteinuria and slow down kidney function decline in obese patients with kidney disease. Surgical interventions also show promise in normalizing kidney filtration rates.
A new study found that extending preventive treatment for CMV infection post-kidney transplant reduces the risk of disease by nearly two-thirds. This approach also proves cost-effective, offsetting increased costs with reduced cases of CMV disease.
A new study from St. Michael's Hospital reveals that patients with acute kidney injury requiring in-hospital dialysis are three times more likely to need long-term dialysis later in life. Early medical surveillance and intervention may prevent progression to irreversible end-stage kidney disease.
A study found that hospitalized patients with acute kidney injury requiring dialysis have a higher risk of chronic dialysis, but not increased mortality rates. Patients who survive hospitalization complicated by acute kidney injury requiring dialysis remain at high risk of needing dialysis for 3-5 years.
The ERC is funding top researchers, including Sanna Lehtonen's group, to study the development of albuminuria and diabetic nephropathy. They aim to identify novel drug leads to treat insulin resistance and combat early stages of kidney disease.
Researchers at UT Southwestern Medical Center found a significant link between depression and early-stage chronic kidney disease, with 57 out of 272 participants identified as depressed. The study suggests that depression screening should be considered for patients in the early stages of chronic kidney disease.
Concomitant kidney dysfunction and worsening renal function in heart failure patients are associated with a poor prognosis. New treatments target improving renal function and preventing its deterioration during hospitalizations for acute heart failure.
Researchers found that retrieving kidneys from uncontrolled non-heart-beating donors after sudden out-of-hospital cardiac arrests can lead to a 10% increase in transplantation rates. The procedure, which raises ethical concerns, has the potential to alleviate organ shortages.
A study of 1,239 patients found that night home hem dialysis can extend life expectancy similar to a kidney transplant from deceased donors. The treatment allows patients to live longer and maintain independence. Night home hemodialysis may be suitable for high-risk patients or those waiting for a transplant.
A new study finds that single kidneys from very young deceased donors can maintain the health of an adult with kidney failure. The research suggests that this practice is safe and effective, offering an alternative to traditional organ allocation methods.
Researchers have developed a Wearable Artificial Kidney that provides continuous dialysis 24/7, reducing hospitalization rates and improving quality of life. The device is powered by two nine-volt batteries and weighs about 10 pounds.
A DASH-style diet high in calcium, potassium, and magnesium, and low in sodium, was found to reduce the risk of kidney stone formation. Participants with higher scores on this dietary approach were between 40-45% less likely to develop kidney stones than those with lower scores.
A study found that female recipients of male donor kidneys have a higher risk of transplant failure in the first year after transplantation. However, this increased risk is reversed after ten years. The study suggests that H-Y antigens on male cells may elicit an immune response in female kidney transplant recipients.
A new laboratory test called urine neutrophil gelatinase associated lipocalin (NGAL) has been found to help predict acute kidney injury (AKI) in intensive care patients. NGAL levels are also higher in patients with HIV-associated nephropathy, a complication of HIV affecting African Americans and black Africans.
Researchers at Columbia University Medical Center have discovered a protein called NGAL that can help diagnose kidney disease caused by HIV. High levels of the protein in urine may indicate the presence of HIV-associated nephropathy, allowing for earlier intervention and potentially preventing kidney failure.
A daily supplement of potassium citrate has been found to prevent kidney stones in children on the high-fat ketogenic diet, a common treatment for epilepsy. The study, published in Pediatrics, showed that those who received potassium citrate twice daily were seven times less likely to develop kidney stones.
A daily dose of sodium bicarbonate slows the decline of kidney function in patients with advanced chronic kidney disease, reducing the rate of progression by about two-thirds. Patients taking baking soda also experience improvements in nutrition and are less likely to develop end-stage renal disease.
A new procedure called CESA combines endovascular and surgical approaches to treat high-risk aortic aneurysms. The technique has shown excellent results in the first 20 high-risk patients with complex aortic pathology treated with CESA, with a cumulative survival rate of 76% at two years.
Researchers have found that the circadian clock protein Period 1 regulates expression of the renal epithelial sodium channel in mice, leading to decreased sodium loss in urine. Additionally, a study on gene therapy revealed that TLR9-MyD88 pathway is critical for adaptive immune responses to AAV vectors. Another study on kidney repair ...
A treatment that significantly slows the progression of eye injury in people with type 1 diabetes has been found. The treatment uses an antihypertensive medication commonly prescribed to treat high blood pressure, and was shown to slow diabetic eye damage in over 65% of participants.
Scientists have identified PLA2R, a protein found in normal human glomeruli, as the target antigen in idiopathic membranous nephropathy. This discovery holds promise for developing a blood test to replace kidney biopsies and determining which patients are most likely to benefit from immunosuppressive treatment.
A recent study found that contrast-induced kidney damage from medical imaging procedures increases the risk of having a stroke or heart attack over the next year or two. Patients who developed this damage had twice as many long-term negative health effects compared to those whose kidneys were not damaged.