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Life Sciences

Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.

447,757 articles | 2542 topics

Health and Medicine

Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.

431,843 articles | 751 topics

Social Sciences

Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.

260,756 articles | 745 topics

Physical Sciences

Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.

257,913 articles | 1552 topics

Applied Sciences and Engineering

Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.

225,386 articles | 998 topics

Scientific Community

Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.

193,043 articles | 157 topics

Space Sciences

Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.

29,662 articles | 175 topics

Research Methods

Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.

21,889 articles | 139 topics

Mathematics

Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.

3,023 articles | 113 topics

Thyroid treatment can trigger homeland security detectors

High levels of radiation from thyroid treatment can trigger homeland security detectors, which are now more common with increased sensitivity. Hospitals should develop documentation guidelines for patients undergoing nuclear medicine procedures to minimize this risk.

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Excess thyroid hormone harmful to fetus

A recent study published in JAMA found that excessive maternal thyroid hormone levels can lead to miscarriage and negatively impact fetal growth, with unaffected fetuses being more susceptible to these effects. The study also discovered that high maternal thyroid hormone levels can induce a catabolic state during fetal life.

Excess thyroid hormone associated with increased rates of miscarriage

A new study has found that high levels of thyroid hormone are linked to an increased risk of miscarriage in women who are resistant to normal levels. The research, conducted on a family with a rare genetic disorder, revealed a significant increase in miscarriage rates among affected mothers compared to unaffected relatives.

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New compound may act to keep thyroid activity in check

Researchers discovered a new compound, T1 amine, that rapidly induces hypothermia, slows heart rate, and drops blood pressure in mice. This effect may provide a valuable tool to manage patients with acute hypermetabolic states, including hyperthyroidism.

SAGE-acious prediction of thyroid carcinoma

Researchers developed a preoperative diagnostic test that uses gene expression to distinguish between benign and malignant thyroid carcinoma. The test has the potential to improve diagnosis accuracy and treatment outcomes for patients with thyroid cancer.

Thyroid cancer study simplifies follow-up exams for patients

A new study published in The Journal of Nuclear Medicine found that taking patients off thyroid medication for only two weeks prior to a scan produces the desired changes in nearly 90% of patients. This simplified approach reduces the need for six-week follow-up scans, making it easier and quicker for patients.

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JCI Table of Contents, 15 August 2003

Asthma patients treated with bronchodilating beta-agonist medications may develop increased sensitivity to airway constriction, experience exacerbation of their condition. Researchers suggest that therapeutics targeting phospholipase C-beta may have substantial benefit in the treatment of asthma.

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Hypothyroidism associated with reduced breast cancer

Researchers found women with hypothyroidism are 57% less likely to develop aggressive, estrogen-sensitive breast cancer. The study suggests a possible biological role of thyroid hormone in breast cancer and offers novel preventive strategies.

URI oceanographers test method to control metamorphosis in summer flounder

Researchers at the University of Rhode Island have developed a novel treatment using thiourea and thyroxine to synchronize the settlement and growth of summer flounder. This method reduces cannibalism and increases the profitability of flounder aquaculture, saving culturists time and effort in fish grouping.

Alcohol consumption during pregnancy alters thyroid function

A study found that alcohol consumption during the third trimester of pregnancy alters thyroid function in both mothers and fetuses, which could lead to brain defects. The researchers used sheep as a model and administered varying doses of alcohol to pregnant ewes, resulting in altered thyroid hormone levels in both mother and fetus.

Evolutionary change leapfrogs over tadpoles

Researchers found a species of frog in Puerto Rico that develops directly from eggs into fully formed adults, retaining the need for thyroid hormone despite bypassing the tadpole phase. This discovery showcases a classic case of evolutionary change in development, where the species adapted to evade predators by losing the tadpole stage.

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