Articles tagged with Thyroid Gland
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A Brigham and Women's Hospital report suggests exposure to iodinated contrast media may cause hyperthyroidism and overt hypothyroidism. The study found significant associations between contrast media exposure and the development of thyroid dysfunction in patients without preexisting conditions.
A Mayo Clinic study finds that nine out of ten commercially available thyroid support supplements contain animal-derived hormones, posing a risk to users' health. The supplements can cause significant side effects, including increased heart rate and nervousness, if taken in excess.
Scientists developed a small molecule, SJ-AK, that selectively blocks a thyroid hormone signaling pathway. This approach could lead to more tailored drugs with fewer side effects, offering new hope for treating conditions like leukemia and autoimmune disorders.
A superior-inferior nerve identification technique during thyroid removal surgery significantly reduces complications, including paralysis of the recurrent laryngeal nerve and hypoparathyroidism. The study found fewer permanent cases of these conditions with this approach.
A new study finds that California pregnant women have the highest reported exposures to PBDE flame retardants worldwide. The research suggests a link between PBDE levels and thyroid-stimulating hormone, which regulates thyroid activity.
The new clinical guidelines for managing thyroid disease in pregnancy focus on diagnosing and treating subclinical hypothyroidism, overt hypothyroidism, and postpartum thyroiditis. They aim to improve patient care and drive future research.
A study published in CMAJ examined the incidence of thyroid dysfunction in patients taking brand-name versus generic amiodarone formulations. The results showed no significant difference in rates of thyroid dysfunction between the two groups, with comparable incidence rates for hypothyroidism and hyperthyroidism.
A large-scale study by the University of Michigan found a link between phthalates and BPA exposure and decreased thyroid hormone levels in adults. The study suggests that exposure to these chemicals may have significant health implications, particularly for fetal and child development.
A recent study published in the Journal of Clinical Endocrinology & Metabolism found that BMC conducts a high rate of thyroid function testing in pregnant women. The study detected approximately 80 percent of cases of mild hypothyroidism that may have gone undiagnosed without routine testing.
The new guidelines provide evidence-based recommendations for optimal care of patients with hyperthyroidism, including treatment options and patient management strategies. The guidelines are a comprehensive update to previous versions and highlight the latest scientific literature and expert experience.
A recent study has linked subclinical hyperthyroidism in elderly individuals to a significantly increased risk of death. The research found that those with this condition were 65% more likely to die during a six-year follow-up period than those with normal thyroid function.
Researchers found that low doses of penta-BDEs altered gene expression in reproductive organs and thyroid hormones in female rat offspring exposed in utero and via maternal milk. Osteopontin gene expression was significantly increased, which may have long-term implications for human health.
The American Thyroid Association has released new practice recommendations for outpatient radioiodine treatment, emphasizing travel precautions, personal hygiene, and pregnancy safety. The guidelines comply with US Nuclear Regulatory Commission regulations and provide simplified instructions for care providers and patients.
A gene variation passed on by mothers to their sons makes them vulnerable to fetal alcohol exposure, disrupting thyroid hormone balance and causing behavioral deficits. Researchers propose dietary supplements to reverse or fix enzyme dosage in the brain, potentially treating FASD.
Researchers found that Hashimoto's thyroiditis symptoms persist even when thyroid function is normal, affecting quality of life. Women with higher levels of anti-thyroid antibodies experienced more symptoms.
Researchers at the NIH have identified a compound that prevents overproduction of thyroid hormone, potentially improving treatment for Graves' disease. The receptor antagonist has not yet been tested in animals or people and still needs to undergo safety testing before potential human trials.
Researchers at UT Southwestern Medical Center discovered a link between anti-TPO antibodies and placental abruption in pregnant women. The study of over 17,000 women found that antibody-positive women were three times as likely to experience placental separation during labor.
A new study found that pregnant women with higher blood levels of a common flame retardant had altered thyroid hormone levels, which could impact fetal growth and brain development. The study linked exposure to these chemicals to decreased TSH levels and an increased risk of subclinical hyperthyroidism.
A study demonstrated the transfer of maternal thyroid hormones to the fetus in vivo, critical for fetal development. This finding clarifies indirect evidence of maternal thyroid hormone passage to the fetus during pregnancy, with significant implications for the development of the nervous system and overall quality of life.
A new experimental thyroid drug, Eprotirome, lowers cholesterol levels without causing the classic thyroid risks to the heart and bone. It also reduced lipoprotein A levels by 33%.
Recent studies suggest that triggering TLR7 and TLR8 can actually increase tumor cell survival, while a new soluble factor IFN-beta represses tumor growth by limiting blood vessel formation. Additionally, microRNA-31 has been identified as an oncogenic factor promoting lung cancer through the repression of specific tumor suppressor genes.
Researchers found that high iodine intake during pregnancy increases the risk of thyroid dysfunction in mothers. The study's findings highlight the need to monitor iodine nutritional status before recommending supplements. Iodized salt is still essential for maintaining proper thyroid function and preventing potential health issues.
Researchers found a solid statistical link between higher concentrations of PFOA in blood and thyroid disease in adults. Individuals with the highest PFOA concentrations were more than twice as likely to report current thyroid disease.
Women with a history of preeclampsia may be at increased risk for reduced thyroid functioning, according to researchers. The study found that women who developed preeclampsia during pregnancy had higher levels of thyroid-stimulating hormone (TSH) and were more likely to have hypothyroidism later in life.
The American Thyroid Association has released new guidelines for managing thyroid nodules and thyroid cancer, focusing on clinical evaluation, fine-needle biopsy, and surgical management. The revised guidelines aim to provide a framework for the care of patients with nodular thyroid disease and thyroid cancer.
A study examined thyroid surgery complications in patients aged 21-65. Results showed similar rates of complications between younger and older patients, with higher readmission rates due to hypocalcemia in the elderly group.
A multi-year study of 428 thyroidectomy patients found only slight differences in rates of complications and hospital readmissions between older and younger patients. Elderly patients had a slightly higher hospital readmission rate due to transient calcium levels issues, not age-related complications.
Researchers have found a genetic link between inherited cardiac arrhythmias and thyroid dysfunction, suggesting that mutations in the KCNE2 and KCNQ1 genes could also cause thyroid problems. The study's findings may lead to new treatments for both heart and endocrine diseases.
A new animal study has identified a specific genetic cause of fetal alcohol-related developmental disorders, which may lead to targeted treatment. Fetal alcohol exposure can disrupt thyroid hormone levels, leading to neurodevelopmental disorders such as emotional behavioral disorders and deficits in learning, memory, and speech.
The American Thyroid Association has developed comprehensive guidelines for diagnosing, treating, and monitoring patients with Medullary Thyroid Carcinoma (MTC), an uncommon form of thyroid cancer. The guidelines cover a range of clinical topics and propose directions for future research.
Pregnant women undergoing thyroid and parathyroid surgery experience higher rates of complications, longer hospital stays, and increased economic costs compared to non-pregnant women. The study highlights the need for cautious approach and careful deliberation on benefits versus risks.
Prenatal vitamin manufacturers are encouraged to use only potassium iodide, not kelp, for a consistent daily iodine dose of 150µg. Iodine deficiency affects 2.2 billion persons worldwide and can cause preventable mental retardation.
A new study published in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that cigarette smoking during pregnancy is associated with changes in maternal thyroid hormone levels. Smoking-related changes in thyroid function extend to the fetus, potentially leading to impaired neuropsychological development.
A new study finds that pediatric obesity can alter thyroid function and structure, with a potential link between fat excess and thyroid tissue modification. Thyroid function returns to normal after weight loss, but the persistence of abnormalities in obese children may progress into chronic disease in early adulthood.
Women with low or high thyrotropin hormone levels have a higher risk of developing Alzheimer's disease, according to a recent study. The research found that these hormone levels were associated with an increased risk of incident Alzheimer's disease in women, but not in men.
A study found that babies born to mothers living in the Seveso area after a 1976 chemical accident are six times more likely to have altered thyroid function. Maternal exposure to dioxins has been shown to damage the function of their babies' thyroid gland.
Researchers found a significant increase in follicular adenoma risk among persons exposed to radioactive fallout from Chernobyl as children and adolescents. The study suggests exposure to radiation at young ages increases the risk, with women having a notably higher risk compared to men.
A new study found that levo-thyroxine treatment did not lower weight or BMI in children with acquired hypothyroidism. Most subjects gained weight, while about a third experienced short-term weight loss due to extremely severe cases of the disease.
A new drug has been found safe and effective at reducing levels of 'bad' LDL cholesterol by up to 40 percent, a promising approach for treating high cholesterol and related conditions. The drug accelerates the natural process of ridding the body of LDL, offering an alternative to statins and potentially complementing their use.
Researchers at Albert Einstein College of Medicine have found that perchlorate, an industrial pollutant linked to thyroid ailments, is concentrated in breast milk. High levels of perchlorate may deprive infants' thyroid glands of iodide, leading to mental impairment.
A 12-year study found a significant increase in differentiated thyroid cancer cases, with small subclinical tumours accounting for the rise. Advances in medical imaging are thought to be responsible for the increased detection rate, rather than a change in disease patterns.
A study published in JCI reveals that Gq/G11-mediated signaling plays a crucial role in transmitting TSH-induced signals, regulating thyroid gland function. Mice lacking the alpha-subunits of both Gq and G11 exhibited reduced thyroid gland function and symptoms similar to hypothyroidism.
A study published in JCI Journals reveals that Gq/G11-mediated signaling plays a crucial role in regulating thyroid gland function. Mice lacking these proteins had impaired thyroid function and symptoms similar to hypothyroidism, highlighting their potential as therapeutic targets for hyperthyroidism.
Researchers at Rutgers University are studying the connection between thyroid hormones and sleep. The study aims to identify how thyroid hormones affect brain structures during sleep and wakefulness.
Researchers at Georgetown University Medical Center developed a fast and accurate test to measure thyroid hormones, which may help diagnose and treat conditions like hypothyroidism and hyperthyroidism. The new test uses tandem mass spectrometry and is more specific than the current immunoassay test.
Researchers found that incorporating cosmetic principles into thyroid surgery can lead to better aesthetic results. The study analyzed 248 patients who underwent varying approaches to thyroid surgery, including minimally invasive and endoscopic methods.
Researchers studied hypothyroidism's impact on brain metabolism and found a correlation between the condition and decreased metabolic activity in specific brain regions. These changes remain detectable even after thyroid hormone replacement therapy, suggesting a complex relationship between physical health and mental well-being.
AkaRx has licensed the tetrac patents for treating thyroid cancer, developing AKR-201 to suppress TSH production. The drug aims to reduce side effects of hyperthyroidism in patients with thyroid cancer
During fasting, brain cells responsible for stimulating appetite make sure you stay hungry. The researchers revealed a link between active thyroid hormone in the brain and increases in an 'uncoupling' protein (UCP2) that boosts power-generating mitochondria, allowing the brain's hunger center to remain active.
A new study found that longer-lived rodents have significantly lower levels of a thyroid hormone that regulates metabolic rate. The study suggests an important regulatory role of thyroid hormone in longevity, with higher thyroid hormone levels correlating with shorter lifespans.
Bitter taste perception varies among individuals due to genetic differences, influencing the detection of toxins like glucosinolates in vegetables. This study establishes a link between bitter taste receptors and toxin detection, providing insights into evolutionary mechanisms.
Research reveals that a specific receptor gene's variation affects perception of bitter compounds in plants, such as glucosinolates found in broccoli. This study supports the idea that evolution shaped human taste preferences to avoid thyroid-inhibiting compounds.
A new study found that calorie restriction decreases tumor necrosis factor alpha and lowers T3 levels in humans, suggesting it may slow the aging process. The researchers also found no association between body fat levels and serum T3 concentrations.
A comprehensive survey of 4,091 atomic bomb survivors found a significant association between radiation dose and the prevalence of thyroid diseases, including malignant and benign tumors. Those exposed at younger ages showed higher dose-response relationships for thyroid cancers and nodules.
Researchers found that patients with mildly underactive thyroid glands showed no increased risk of heart attacks, strokes, or death. However, those with a mildly overactive thyroid gland had a small increased risk of developing an abnormal heart rhythm.
A study of 3,233 individuals aged 65+ found that subclinical hyperthyroidism was associated with an increased risk of developing atrial fibrillation. However, the study did not find a link between abnormal thyroid function and other cardiovascular problems.
Researchers have discovered a new treatment option for thyroid cancer that allows patients to continue their thyroid hormone replacement therapy while undergoing radioiodine treatment, reducing unpleasant side effects. This breakthrough could improve the overall quality of life for thyroid cancer patients during treatment.
Reduced thyroid hormone signaling during development leads to extreme anxiety and memory impairments in adulthood. Dietary supplementation with thyroid hormone can suppress anxiety and improve memory in adult mice.
Researchers have found that an incision about half the length used for traditional surgery works just as well in removing diseased thyroids. The minimally invasive approach is safe, likely speeds wound healing, and has a superior cosmetic result.
A new study demonstrates that moderate thyroid hormone therapy normalizes cardiac cell shape and reduces stress on the heart's wall by nearly 40%. This change may lead to a novel therapeutic approach for heart failure. Further animal studies are needed before human testing.