Articles tagged with Dissection
A 3D model of Henry Molaison's (H.M.) brain has been created, providing new insight into the neurological basis of his severe amnesia. The study reveals a small lesion in the left orbitofrontal cortex that was likely created during H.M.'s 1953 surgery, which may help scientists understand the consequences of similar operations today.
A multi-institutional team has found a recurrent genetic mutation, PRKG1, linked to thoracic aortic dissections in families with young members. The mutation causes muscle cells in the aorta wall to respond incorrectly to blood flow, leading to aneurysms and acute dissections.
A retrospective clinical controlled study found that dissecting the recurrent laryngeal nerve during thyroid surgery significantly reduces the risk of nerve injury. The study analyzed data from 5,344 patients and showed a lower incidence of nerve injury in those undergoing nerve dissection.
A recent study at Rhode Island Hospital found that acute aortic dissection repair performed in the waning full moon reduces the odds of death, while full moon cycles are associated with shorter length of stay. The study's findings suggest that lunar cycles may play a role in cardiac patient outcomes.
A phase III non-inferiority trial found that axillary radiotherapy provides excellent regional control and reduces the risk of lymphoedema compared to axillary lymph node dissection. The study also showed no significant differences in overall or disease-free survival between the two treatment arms.
Researchers found that the mortality rate for type A acute aortic dissections is still extremely high, with a near 1% per hour risk during the initial onset. The study suggests that medical management alone may not be sufficient to reduce mortality rates, emphasizing the need for rapid diagnosis and intervention through surgery.
A new study reports that endoscopic mastoscopic axillary lymph node dissection (MALND) reduces blood loss, pain, and swelling compared to conventional surgery. MALND also shows promise in reducing distant metastasis rates and improving aesthetic outcomes.
Researchers from UTHealth and France have discovered a gene defect linked to systemic complications including life-threatening thoracic aortic disease and intracranial aneurysms. The new syndrome is similar to Marfan and Loeys-Dietz syndromes but distinct in its genetic cause.
A new study recommends that breast cancer patients with a positive ultrasound-guided axillary node biopsy undergo an axillary dissection due to more extensive disease. Patients with a negative biopsy can instead have a sentinel lymph node biopsy.
A recent study published in The Journal of Sexual Medicine has confirmed the anatomic existence of the G-spot, a previously elusive structure. The G-spot was found to be a well-delineated sac structure located on the dorsal perineal membrane, measuring 8.1mm x 3.6mm x 0.4mm in dimensions.
A study found that dissections occur most frequently in the right coronary artery and bending areas, causing serious complications. Stenting was successful in treating the dissection in 75% of patients, but major in-hospital adverse events occurred in 54%.
A study found that patients with BAV have an increased risk of aortic dissection, with a 8.4 times higher risk compared to the general population. The 25-year risk of aortic surgery was also high, at 53%. The researchers highlight the importance of close monitoring and early recognition for prevention.
A new study by UTHealth and BCM researchers identified a common genetic variant associated with an increased risk of thoracic aortic aneurysms and acute aortic dissections. The variant, located on chromosome 15q21.1, involves the FBN1 gene, which is also linked to Marfan syndrome.
A study found that people with duplications in chromosome 16's 16p13.1 region are at 12-fold increased risk of thoracic aortic aneurysms and dissections. Researchers from UTHealth and Baylor College of Medicine discovered this association, which may lead to aggressive forms of the disease and require closer monitoring.
Researchers at UTHealth have discovered a link between chromosome region 16p13.1 and thoracic aortic disease, finding that patients with duplications are 12 times more likely to develop the condition. The study identified nine genes in this region, which may contribute to the development of aneurysms and dissections.
A new risk score can effectively identify patients with acute aortic dissection, which has a high mortality rate. The tool uses simple bedside screening to detect the condition's symptoms, including sudden, intense pain, and is backed by a large study involving over 2,500 patients.
Small-screen detected lung cancers with maxSUV of 2.0 or smaller nodules than 10mm have low risk of nodal metastases, suggesting some patients can avoid invasive procedures. This reduces operating time and morbidity associated with lymph node dissection.
In experiments with African cichlid fish, scientists found that females show increased anxiety and decreased attraction when their preferred male loses a fight. Conversely, when the male prevails, the female's brain shows increased activity associated with reproduction and pleasure. These findings suggest that humans may experience sim...
Researchers at UT Southwestern Medical Center have found that amphetamine abuse increases the risk of aortic dissection in young adults. The study, published in American Heart Journal, analyzed medical records from nearly 31 million people and found a threefold increase in odds of aortic dissection among those who abused amphetamines.
A regional protocol initiative improved aortic dissection patient care, reducing time to diagnosis from 4.3 hours to 160 minutes. The protocol, implemented in 32 hospitals, also led to a 55% reduction in time to intervention for surgically managed patients.
Research published in The Journal of Nuclear Medicine suggests that molecular imaging using 18F-FDG PET/CT can help diagnose acute and chronic aortic dissection. This non-invasive technique can provide images to determine the difference between acute and chronic dissections, helping doctors decide the best course of treatment.
A study published in World Journal of Gastroenterology reports successful endoscopic resection of a large ileal lipoma using the modified endoscopic submucosal dissection (ESD) technique. The procedure, combined with endoscopic unroofing, allowed for complete removal of the lesion without complications.
The new clinical guidelines offer recommendations for the diagnosis and management of thoracic aortic disease, highlighting the importance of early detection and treatment. Risk factors include high blood pressure, age, male gender, and genetic conditions that weaken connective tissue.
A new study reveals a more extensive valley network on Mars, indicating the presence of an ancient ocean. The findings suggest that rainfall and precipitation played a major role in shaping the Martian landscape.
Researchers at Harvard University used an analog model and mathematical simulations to understand how a long leaf is formed. They found that elastic strain resulting from differential growth leads to the elegant arc and serrated surface of leaves like the plantain lily.
Researchers found that inflammation is critical in aortic dissection and interleukin-6 plays key role. Studies using mice and human samples validate findings, providing new insights into underlying mechanisms.
Researchers at the University of Utah developed three new iPhone apps to help scientists, students, and doctors study human anatomy and analyze medical images. AnatomyLab allows users to dissect a cadaver in 40 layers, while ImageVis3D Mobile enables interactive 3-D visualization of large data sets.
A study published in World Journal of Gastroenterology found that a large number of dissected lymph nodes in D2 dissection improves long-term survival and reduces recurrence rate for patients with node-negative gastric cancer. The number of resected lymph nodes is a key prognostic indicator, and increasing it leads to better survival o...
Researchers at UT Houston have identified a single gene defect that causes thoracic aortic aneurysms, dissections, coronary artery disease, ischemic stroke, and Moyamoya disease. The study found that mutations in the ACTA2 gene can lead to increased smooth muscle cell multiplication, contributing to blocked or enlarged arteries.
Researchers demonstrate feasibility and safety of magnetic-anchor-guided endoscopic submucosal dissection (MAG-ESD) for large early gastric cancer in humans. The technique facilitates en bloc removal of lesions by providing retraction capability using magnets, simplifying the procedure.
UT-Houston researchers have identified a defective gene mutation in smooth muscle alpha-actin (ACTA2) that affects vascular smooth-muscle cells, leading to thoracic aortic aneurysms and dissections. The study suggests that contraction of the smooth muscle cells in the aorta is crucial in maintaining its health.
A 53-million-year-old fossilized spider has been digitally dissected using VHR-CT, revealing internal organs for the first time. The technique has revolutionized the study of amber fossils, providing a unique window into past forest ecosystems.
Researchers propose new model for predicting post-hospital death risk in aortic dissection patients based on blood clotting in the false lumen. Partial clotting is associated with a much greater risk of death, while those with patent or completely thrombosed false lumens have intermediate and lower risks respectively.
A study published in Neurology found that methamphetamine use is associated with an increased risk of major neck artery tears and stroke. The research reviewed two cases of women who experienced sudden speech difficulty and weakness after using the drug, resulting in severe strokes from carotid artery dissection.
A new book explores how primary-care doctors interact with patients, focusing on both physician and patient contributions. The research aims to understand the social organization of medical talk and improve doctor-patient relationships.
Researchers found that 90% of patients who survived emergency surgery and hospitalization for aortic dissection would be alive three years later. Those without pre-existing heart and blood vessel problems were more likely to survive, with a quarter having hypertension and nearly 25% having atherosclerosis before their dissection.
Researchers are creating a high-resolution, 3D online catalog of fishes using MRI technology, allowing for the digital dissection of preserved specimens. The Digital Fish Library project will image at least one fish family per 482 families worldwide, promoting biodiversity research and education.
Endovascular stent grafting successfully treats abdominal and thoracic aneurysms and type B aortic dissections. The procedure has been shown to reduce mortality rates compared to surgery in certain cases.
Researchers have identified gene mutations that cause life-threatening aortic aneurysms and dissections, providing a new molecular pathway for therapy development and early warning signs. The study found four families with variations in the TGFBR2 gene, which alters protein structure and sends incorrect signals.
Fine-needle aspiration of axillary lymph nodes has been shown to be a safe and effective alternative to sentinel lymph node biopsy or axillary dissection for patients with suspected breast cancer. The procedure allows for precise treatment and can help avoid unnecessary surgeries, saving money and time.
A study published in Journal of Clinical Oncology found that extended lymph node dissection does not increase long-term survival among gastric cancer patients, potentially increasing morbidity and hospital mortality. The procedure may only be beneficial if safe and effective alternatives can be developed.
Research finds that spinal manipulative therapy may exacerbate pre-existing vertebral artery dissections, increasing the risk of stroke. Patients under age 60 who received chiropractic neck treatments were six times more likely to experience a stroke than those who didn't.
A new study by the American Academy of Neurology links cervical spine manipulation to an increased risk of stroke in people under 60. Researchers found that patients who experienced arterial dissection and stroke were six times more likely to have visited a practitioner who manipulated their neck within the past 30 days.
A new study has found that cocaine use is associated with an increased risk of aortic dissection, a potentially fatal condition. The research, led by UCSF cardiology fellow Priscilla Hsue, highlights the importance of healthcare providers being aware of this potential risk factor and recognizing early signs of the condition.
Aortic dissection is a life-threatening condition that can occur in people who have used crack cocaine, particularly those with high blood pressure or Marfan syndrome. Researchers found that 29% of cocaine users died from the condition compared to 17% of non-users.
A study examining cervical manipulation and its potential risks found an estimated rate of 1 arterial dissection per 5.85 million manipulations, significantly lower than previous estimates. Practitioners should discuss the benefits and risks with patients to ensure informed decision-making.
A University of Iowa-led study found that women with Stage I breast cancer who did not receive axillary node dissections had significantly worse 10-year survival rates compared to those who underwent the procedure. The analysis suggests that many women with early-stage disease are not receiving this crucial treatment, which may impact ...
A new nonsurgical technique using stent-graft placement has been shown to be effective in treating people with life-threatening aortic dissection. The catheter-delivered procedure involves inserting a wire mesh tube to force open and maintain the blocked aorta, reducing complications and mortality rates.