Articles tagged with Memory Disorders
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A study published in Diabetes Care found that brain function slows in individuals with type-2 diabetes and high stress hormone cortisol levels. Higher cortisol levels have been associated with cognitive decline in this population.
A study of 990 older adults found that hypertension predicts dementia progression in those with executive function deficits, but not in those with memory dysfunction. Control of hypertension may decrease the projected rate of dementia progression by half.
A medication called latrepirdine has been found to be well-tolerated in patients with mild to moderate Huntington's disease. The treatment showed improved average scores on an evaluation measuring overall cognitive function, suggesting potential benefits for cognition.
Researchers identified a gene variant that affects mice's response to natural hormone fluctuations, leading to increased anxiety and impaired memory. The study suggests the gene may play a role in premenstrual dysphoric disorder (PMDD) and other menstrual cycle-related disorders.
A new report reveals that a prion-like protein called CPEB may participate in memory in higher eukaryotes, including sea slugs. The protein's ability to switch between distinct conformational states suggests it could maintain stable states with unstable biological molecules.
A new magnesium compound, MgT, has been shown to boost learning abilities, working memory, and short- and long-term memory in rats. The study suggests that maintaining normal or higher levels of magnesium may help slow age-related loss of cognitive function and prevent diseases affecting cognitive function.
A study published in ACS' Journal of Agricultural and Food Chemistry found that blueberry juice supplementation improved learning and memory tests in volunteers aged 70-72. The researchers suggested that consistent blueberry consumption may offer an approach to mitigate neurodegeneration.
Researchers found a link between a specific gene variation and slower memory decline, as well as a lower risk of developing dementia and Alzheimer's disease. The study suggested that this protective association may be due to the gene's role in lipid metabolism.
A combination of nutrients, including uridine, choline, and DHA, has shown promise in improving verbal memory in patients with mild Alzheimer's disease. The study found that 40% of treated patients improved performance in a test of verbal memory, while 24% of control subjects showed improvement.
A new brain scan, diffusion tensor imaging (DTI), has been shown to detect changes in the hippocampus that are associated with memory decline. DTI-MRI scans were found to be more accurate than traditional MRI in identifying changes related to Alzheimer's disease.
A new study published in the Journal of Alzheimer's Disease suggests that long-term cell phone exposure may protect against and even reverse Alzheimer's disease. The research found that electromagnetic waves generated by cell phones erased brain deposits of beta-amyloid, a hallmark of Alzheimer's disease, in mice.
UCSB scientists have made a major discovery in how the brain encodes memories. They found that strengthening synapses, which cement memories into place, involves making new proteins. The production of these proteins is regulated by RNA and microRNA, and degradation of silencing molecules allows for protein synthesis.
Researchers successfully blocked a conditioned fear memory in humans for at least a year using a noninvasive technique that exploits the reconsolidation window of emotional memories. The method, inspired by animal studies, shows promise for treating anxiety disorders like PTSD by altering emotional memories during their recall.
Researchers at NYU have developed a non-invasive technique to block the return of fear memories by updating them with non-fearful information during the reconsolidation process. This technique, shown to be effective in reducing fear responses, may lead to new ways to treat anxiety disorders.
Researchers from the University of Toronto have discovered that the hippocampus is only activated when context cues enable memory recall. This finding sheds light on the mysterious process of retrieving memories, particularly in individuals with damage to the hippocampus, such as those with Alzheimer's or Epilepsy.
Researchers at Washington University School of Medicine studied 575 patients who underwent surgery and found no evidence of long-term cognitive decline. The study suggests that if older adults physically recover from surgery, they will return to their previous level of cognitive ability within six months or a year.
Researchers found that transplanted stem cells restored learning and memory to normal levels in rats four months after radiotherapy. The treatment showed promise in reversing radiation-induced damage of healthy tissue in the brain.
Research published in Neurology suggests that people with both diabetes and Alzheimer's disease have a slower rate of memory loss than those with only Alzheimer's. The study found that diabetes may actually counteract the progression of cognitive decline in Alzheimer's patients, although the reasons for this effect are still unclear.
Research using animal models has identified key brain cells and circuits affected by addiction, shedding light on the cognitive problems associated with it. These findings may lead to more effective treatment options to weaken powerful cravings, ultimately guarding against relapse.
A transgenic rat named Hobbie-J was created by over-expressing the NR2B gene, which enhances communication between brain cells. This results in improved memory and learning capabilities, including remembering novel objects and navigating complex tasks.
Researchers found that declines in visuospatial skills and cognitive abilities can occur years before clinical diagnosis of Alzheimer's disease. These findings suggest that conventional methods for diagnosing the disease may not be sensitive to early manifestations of the condition.
Reijmers is investigating the proteins involved in long-term memory storage, with potential applications in treating diseases like Alzheimer's. His research aims to understand the mechanisms of memory and apply them to various fields, including addiction, epilepsy, and spinal cord regeneration.
Researchers at Baylor College of Medicine found that nicotine strengthens neuronal connections in the brain, creating memory associations between environmental cues and smoking behavior. This process is thought to underlie why former smokers often experience strong cravings when exposed to triggers such as bars or meals with friends.
A study found that people with infections were more likely to experience memory loss and cognitive decline compared to those without infections. The study suggests that reducing inflammation may be beneficial for people with Alzheimer's disease.
Researchers at Columbia University Medical Center found that a cancer drug can restore memory deficits in patients with Alzheimer's disease by targeting a previously unknown defect in the brain. The drug works by increasing DNA spool acetylation and gene transcription, leading to improved memory performance.
Researchers at Tel Aviv University use Diffusion Imaging MRI to track memory changes and explore early detection of Alzheimer's disease. The study reveals that brain microstructure can change in mere hours, allowing for a quantifiable measure of individual brain plasticity.
A recent animal model study found that exposure to high concentrations of oxygen hastens memory loss in Alzheimer's mice. The study suggests that the combination of brain beta amyloid and hyperoxia may trigger Alzheimer's symptoms, particularly in those at increased risk. Researchers propose reducing oxygen exposure as a potential prev...
A study of 679 people aged 65 and older found that white matter hyperintensities were strongly linked to memory loss, while infarcts predicted non-memory cognitive problems. The results suggest that brain damage visible on scans may be a predictor of memory decline in old age.
A study published in Neurology found that engaging in brain-exercising activities such as reading and playing card games can delay the onset of rapid memory loss in people with dementia. Participants who engaged in more activities experienced a slower decline in cognitive function.
A study has identified key Alzheimer's brain changes in older individuals with little memory impairment, shedding light on the role of amyloid protein in cognitive decline. The findings suggest that asymptomatic older adults may already be in the early stages of Alzheimer's disease.
A new study suggests that preimplantation genetic diagnosis (PGD) may increase the risk of weight gain and memory decline in adulthood. The research used a mouse model to examine the effects of blastomere biopsy on fetal, neonatal, and adult development.
Researchers at UC Irvine have found that neural stem cells can rescue memory in mice with advanced Alzheimer's disease by secreting a protein called BDNF, which creates new neural connections. This study provides hope for a potential treatment for the leading cause of elderly dementia.
A new Mayo Clinic study found that clinical criteria for mild cognitive impairment are better at predicting Alzheimer's disease than a single memory test. The study identified individuals aged 70-79 years who were cognitively normal or had slight memory impairment as being most likely to develop Alzheimer's disease.
Researchers found that a 'heart healthy' diet, rich in whole grains, vegetables, low-fat dairy, and nuts, may slow cognitive decline. Ongoing moderate physical activity was also associated with improved cognitive function in older adults.
A study found that a drug similar to one used for rheumatoid arthritis and psoriasis can rescue memory in mice with Alzheimer's symptoms. The drug, PMX205, prevented inflammation in brain regions with amyloid plaques, which accelerates neuron damage.
Researchers found that women with higher language scores had a lower risk of developing Alzheimer's disease, despite having hallmark signs of the disease. The study suggested that mental abilities at age 20 may be indicative of a brain better able to cope with diseases later in life.
Brown University political scientist Ross Cheit disputes a 2006 Harvard University psychiatric contest on repressed memory, arguing that the methodology was flawed and no data correction was issued after discovering a pre-1800 literary example fulfilling the criteria
Researchers found that combining antidepressants with electroconvulsive therapy (ECT) improves depression symptoms more than using ECT alone, reducing memory problems, particularly when using nortriptyline or unilateral ECT on the right side of the brain.
Researchers at the University of South Florida found that caffeine significantly decreased abnormal levels of beta amyloid protein in the brains and blood of Alzheimer's mice, reversing their memory impairment. Caffeine administered to elderly non-demented humans also affects their blood levels of β-amyloid.
Researchers have identified a connection between the immune system and schizophrenia, finding genetic variations that disrupt brain development, memory, and cognition. The study's findings hold promise for developing new treatments targeting specific molecular mechanisms involved in the disorder.
The researcher aims to understand how neurons store information and decide which memories to retain. UT San Antonio scientist Brian Derrick is studying the role of the dentate gyrus in preserving episodic memories using a $917,000 NIH grant.
Researchers generated a novel kinase-dead mutant mouse of the CaMKII alpha gene that lacks its kinase activity, leading to severe deficits in hippocampal synaptic plasticity and behavioral learning. The findings support the idea that CaMKII alpha kinase activity is essential for memory functions.
A recent study has identified biomarkers in cerebrospinal fluid that can reveal Alzheimer's disease at a very early stage, even in patients with minimal memory impairment. The findings suggest that these biomarkers can predict the risk of deterioration by 27 times higher than the control group.
A UCLA study reveals that depression may increase the risk of developing Alzheimer's disease in individuals with mild cognitive impairment. Researchers also found that the medication donepezil can delay the progression of Alzheimer's in depressed individuals with memory problems.
A recent study published by the American Academy of Neurology found that individuals with depression and mild cognitive impairment are at a higher risk of developing Alzheimer's disease. The study also showed that taking donepezil may delay progression to Alzheimer's for those with memory problems.
A new study reveals that memory loss is the only reliable factor for predicting dementia risk in elderly individuals, contradicting previous test results. The study's findings highlight the need for continuous adjustments in dementia detection tools as older generations exhibit improved performance on standardized psychological tests.
Researchers at the University of Georgia have discovered that laboratory rats exhibit
A 68-year-old man with Korsakoff's syndrome exhibited an extraordinary ability to recall false memories, surpassing the limits of time and details. This phenomenon, named 'Confabulatory Hyperamnesia', is characterized by detailed false memories that are often plausible and coherent.
A team led by Li-Huei Tsai has pinpointed the exact gene responsible for reversing Alzheimer's-like symptoms in mice. The researchers found that drugs targeting HDAC2 reverse cognitive function and boost memory formation, offering new hope for treating neurodegenerative diseases.
Research reveals that people with emerging symptoms of Alzheimer's disease are less efficient at remembering high-value information. Clinicians may be able to train them to improve their memory by teaching strategic and selective encoding techniques.
Research published in Neurology shows that Alzheimer's patients who develop delirium experience rapid cognitive decline, with a rate three times faster than those without. The study suggests that preventing delirium may improve or delay memory problems.
A study in PLOS Biology found that the intermediate hippocampus plays a critical role in translating rapid place learning into behavior. The researchers used a water maze experiment to test rats and found that disabling a specific region of the hippocampus impaired their ability to return to a platform.
Researchers identify specific brain regions affected by each disease, suggesting a common disease process among all forms of neurodegeneration. The discovery could lead to earlier diagnoses and novel treatment-monitoring strategies.
A new study by scientists from Imperial College London and University of Oxford found that young adults with a genetic variant associated with Alzheimer's Disease exhibit changes in brain activity decades before any symptoms appear. The researchers used functional Magnetic Resonance Imaging (fMRI) to compare the brains of healthy young...
Researchers studied autobiographical memory in semantic dementia patients according to disease progression, finding early-stage patients could recall recent and lasting memories. As dementia evolves, mechanisms behind autobiographical memory impairment result from storage deficits and faulty retrieval strategies.
Researchers at the University of Texas at Austin have discovered a method to manipulate memories of fear by timing the extinction process. By targeting the labile state of fear memories after retrieval, they found that rats exhibited reduced fear responses and smaller chances of spontaneous memory resurfacing. This breakthrough could l...
A study by UC Davis M.I.N.D. Institute found that children with ADHD exhibit variable response times during working memory tasks, even when accuracy is similar to typically developing peers. Higher levels of hyperactivity and impulsivity are associated with slower reaction times.
A new study led by the University of Leicester has found that people with mild cognitive impairment (MCI) have a lower risk of progressing to dementia than previously thought. The research suggests that only 5% of people with MCI develop dementia, contradicting previous estimates of up to 15% per year.
A recent study by UC Irvine researchers found that brief experiences activate neurons and genes associated with memory as effectively as repetitive activities. This discovery can help scientists design better therapies for diseases such as Alzheimer's, which impair the ability to form memories.
Researchers develop a novel approach to treating PTSD by selectively disrupting traumatic memories with a cortisol-blocking drug. The treatment's effectiveness is linked to the intensity of the initial trauma and can be administered shortly before recalling the memory.