Articles tagged with Memory Disorders
Researchers at University of Bristol found that multiple brain regions work together to form memories, particularly in recognizing faces and names. The study's findings have implications for understanding memory disorders like Alzheimer's disease.
Researchers used optogenetics to fragment sleep in mice, finding that minimal uninterrupted sleep is crucial for memory consolidation. The study suggests that compromised sleep continuity, such as in sleep disorders like apnea, may contribute to memory impairments.
A Johns Hopkins University study found that an existing anti-seizure drug improves memory and brain function in adults with a form of cognitive impairment. The findings suggest that the drug may slow the abnormal loss of brain function in some aging patients before their condition becomes Alzheimer's.
Researchers found that holding a memory of a visual event can 'contaminate' visual perception, leading to exaggerated misperceptions. The study used a visual illusion to demonstrate this effect, showing participants reported more dramatic changes in motion direction than actually existed.
Researchers found that transplanted stem cells restored learning and memory abilities in rats, with as few as 100,000 cells sufficient to improve cognition. The study provides hope for future stem cell therapies to alleviate side effects of radiotherapy for brain tumors.
Researchers at Michigan Medicine observed key aspects of brain circuit development in living organisms, revealing two distinct types of competition between cells that shape memory circuits. The findings suggest that the brain eliminates inactive connections to maintain efficient neural networks, which is crucial for learning and memory.
A new study found that a protein called soluble amyloid precursor protein beta (sAPPβ) may be a more accurate predictor of Alzheimer's disease than existing biomarkers. The researchers discovered that sAPPβ levels were significantly higher in participants who developed the disease, with an average of 1,200 nanograms per milliliter.
Researchers have discovered a potential new therapy for Alzheimer's disease, with the cysteine protease inhibitor E64d improving memory deficits and reducing β-amyloid build-up. The study suggests that increasing Cathepsin B activity is not detrimental to memory function, contrary to previous assumptions.
A new study by University of Calgary researcher Dr. David Hodgins highlights the growing issue of problem gambling as access to online gambling increases. Problem gamblers often co-occur with other mental health and substance-abuse disorders, and treatment effectiveness is variable.
Researchers at Penn have found that sleep deprivation affects the hippocampus, a part of the brain associated with memory function. The study identified adenosine as the source of memory loss and attention deficits caused by sleep deprivation.
A new study published in Neurology suggests that more than half of people diagnosed with Alzheimer's disease before age 60 are initially misdiagnosed due to atypical symptoms. Researchers found that 53% of those with no memory problems were incorrectly diagnosed, highlighting the need for biomarkers to improve diagnosis and treatment.
According to a recent report, dementia and mild cognitive impairment are prevalent among 'oldest old' women, who are 85 years of age and older. The prevalence of these conditions increases with age, with the highest rates found in women over 90 years old.
A study demonstrates that monkeys can recall and reproduce simple shapes from memory, mirroring the performance of humans using a standard recall test. This finding suggests that recollection might be an adaptive ability in primates long before humans evolved.
Biologists at UC San Diego discovered that electrical oscillations are critical for the brain to store spatial memories. Grid cells in the entorhinal cortex require precise timing of electrical oscillations to function properly, suggesting a key component in memory processing.
Researchers found cotinine reduced Alzheimer's disease brain plaques and prevented memory loss in mice, showing promising results for a potential therapy. Cotinine also stimulated the survival of neurons and enhanced attention and memory.
A Concordia University study reveals that a cluttered brain can hinder memory, with older individuals struggling to recall and process information. The research suggests that reducing mental clutter and engaging in mentally stimulating activities may help improve memory and cognitive function.
A new Northwestern Medicine study found that hospitalization can lead to temporary memory loss and difficulty understanding discharge instructions in seniors. However, the cognitive impairment typically resolves on its own within a month after hospital discharge.
A UCSF study has found a link between chronic brain inflammation and memory decline in older adults. The study, which examined the effects of C-reactive protein on memory, showed that high levels of this protein correlate with poorer verbal recall and smaller medial temporal lobes.
A study by Kent State University researcher John Gunstad found that bariatric surgery patients showed improved memory function 12 weeks after their operations. The researchers tested 150 participants and discovered a link between weight loss and enhanced cognitive abilities.
A new MRI study published in Radiology suggests that automated brain volume measurements can predict future memory decline in elderly people with normal cognitive ability. The study found high accuracy rates when considering multiple brain regions, including the temporal and parietal lobes.
A recent study by the University of Edinburgh has shed light on how older people experience memory loss, revealing a stress hormone receptor's role in this process. The research found that high levels of cortisol, a stress hormone, activate brain processes contributing to memory impairment.
A new study reveals that environmental enrichment enhances memory by forming new synapses and breaking down old ones, with the β-Adducin protein playing a critical role in this process.
Children with heavy prenatal alcohol exposure (PAE) and ADHD exhibit different patterns of learning and memory impairments. PAE is associated with initial encoding problems, while ADHD affects retrieval mechanisms, suggesting distinct underlying deficits.
A survey of patients with epilepsy found that they ranked memory loss as their second-most important concern, while doctors ranked it 12th. Practitioners were more concerned about unexpected seizures, which was also the top concern for both groups.
Researchers at the NIH have discovered that increasing activity of brain enzyme PKMzeta enhances long-term memories in rats, while decreasing it erases them. This finding has significant implications for treating debilitating emotional memories and enhancing faltering memories in disorders of aging.
A recent study found that individuals with high cholesterol and blood pressure in middle age are more likely to experience early cognitive decline and memory problems. The research, which tracked over 4,800 participants for 10 years, showed a significant association between cardiovascular risk factors and poorer cognitive test scores.
A recent study published by the American Academy of Neurology found that individuals with memory problems are at a higher risk for stroke. The research used two simple tests to evaluate brain function and found that those who scored in the bottom 20% were 3-9 times more likely to experience a stroke, depending on age.
A study published in Neurology found that older people with metabolic syndrome are 20% more likely to experience cognitive decline on memory tests. Higher triglycerides and low HDL cholesterol were linked to poorer memory scores.
Douglas Rosenberg invests $3.5 million with Buck Institute to develop treatments for Alzheimer's disease based on small molecule screenings that show promise. The goal is to raise $10 million to get the new drug candidates into early clinical trials.
A naturally occurring growth factor called IGF-II has been found to enhance retention and prevent forgetting of fear memories in rats. The study suggests that IGF-II could become a potential drug target for boosting memory, with the potential to address clinical problems such as post-traumatic stress disorder.
Researchers tested how brain network integrity relates to future cognitive decline in people with mild memory problems. They found altered patterns of brain activity in the default mode network among those who later progress to Alzheimer's disease compared to those whose memory remains intact.
A BRNI study reveals underlying causes of Alzheimer's degeneration and identifies promising pharmaceutical solutions by normalizing the Alzheimer's brain. Treatments that target synapse growth and preservation have shown to prevent disease progression, shifting focus from amyloid plaques.
Researchers at UCLA have made a groundbreaking discovery about neuronal gap junctions, which could lead to new treatments for anxiety disorders like PTSD. The study found that blocking these gap junctions can disrupt critical rhythms in the brain region most involved in cognition, preventing fear memories from forming.
Researchers found that stress activates memory recall of unrelated experiences in laboratory rats, which may offer insights into post-traumatic stress disorder (PTSD) and related conditions. The study's results suggest that traumatic stress can reactivate non-traumatic memories, linking them to the traumatic experience.
UCI researchers identified a novel mechanism in the brain that boosts memory by strengthening and prolonging memories of negative events to simple objects. Neuropeptide S activation prepares the brain for learning, leading to remarkable memory improvement with long-lasting effects.
Researchers at UT Health Science Center San Antonio have found that increasing a protein called CBP can restore learning and memory in an Alzheimer's disease mouse model. This breakthrough provides a novel therapeutic target for the development of Alzheimer's medications.
Researchers at the University of Cambridge found that brain disruptions cause confusion between memories, leading to false remembering. This insight could lead to new treatments reducing memory confusion and improving daily functioning for patients.
A 10-year study found that walking at least five miles per week protects brain structure and slows cognitive decline in people with Alzheimer's and mild cognitive impairment. The study also showed that physical activity levels are correlated with MRI results and reduced the risk of cognitive decline.
Scientists discovered that increasing EphB2 levels can fix memory problems caused by amyloid proteins in a mouse model of Alzheimer's disease. The study found that blocking amyloid proteins from binding to EphB2 and enhancing its functions may be beneficial for AD treatment.
Researchers have identified a key role for a protein called RyR2 in the development of long-term changes in brain connectivity associated with learning, memory, and addiction. By upregulating RyR2, nicotine can trigger the formation of new connections in the brain, leading to addictive behavior.
Research by University of California, Berkeley psychologists found that chronic jet lag causes persistent changes in the brain's hippocampus, leading to memory and learning problems. The study, which used female Syrian hamsters as subjects, showed that even after recovery from jet lag, the brain continued to experience deficits.
Researchers have identified brain changes in people with Alzheimer's disease, suggesting new diagnostic markers and therapeutic targets. These findings may help identify individuals at risk and improve early detection, potentially leading to more treatable stages of the disease.
Yerkes researchers are presenting various studies on neuroscience topics including social bonding, addiction, neurodegenerative diseases and memory. Researchers like Larry Young, Leonard Howell and Yoland Smith are sharing their findings on oxytocin, stimulant addiction and cell death in neurodegenerative diseases.
A Canadian research team found that bilingual individuals experienced a delay in the onset of Alzheimer's symptoms by as much as five years. The study analyzed clinical records of over 200 patients and found that bilingualism contributed to cognitive reserve, delaying symptom onset.
A University of Toronto study reveals that visual attention diminishes with age, leading to better memory for irrelevant information. Older adults are less capable of filtering out distracting information, which broadly influences cognitive deficits in normal aging.
Researchers have linked anti-inflammatory arthritis drugs to preventing cognitive decline after surgery by targeting a specific inflammatory response in the brain. The findings suggest that these therapies could lead to human clinical trials within 12 months.
Lowering STEP protein levels reversed cognitive deficits in mice with Alzheimer's disease, according to a Yale University study published in the Proceedings of the National Academy of Sciences. The research found that reducing STEP levels is sufficient to reverse cognitive defects in mice without the Alzheimer's mutation.
Researchers at the Gladstone Institutes have discovered that ApoE4 causes learning and memory deficits by impairing GABAergic interneuron function. The study found that apoE4-dependent deficits were rescued by pentobarbital, a compound that enhances GABA action.
A diet rich in luteolin reduces inflammation in the brain and related memory deficits. Luteolin improves cognitive health by acting on microglial cells to reduce inflammatory cytokine production.
Researchers have identified a preclinical candidate that may slow the natural decline in memory associated with ageing. The new synthetic compound selectively blocks an enzyme involved in high levels of 'stress' steroid hormones, which are linked to memory loss.
A recent study found that electric stimulation of the right anterior temporal lobe improved proper name recall by 11% in young adults. This technique, known as tDCS, may also lead to longer-lasting effects and hold promise for treating memory decline in older adults.
A new study published in PLOS ONE suggests that the way the brain processes second-stage learning could be mimicked therapeutically to help people with impaired memory formation. The researchers discovered a new mechanism of learning that is independent of the NMDA receptor, which is currently essential for learning and memory.
A new study reveals that people with a history of cancer are 40% more likely to experience memory problems that interfere with daily functioning. The findings suggest that cancer itself is a key independent predictor of memory issues, going beyond previously recognized conditions like 'chemobrain'.
Researchers at Rush University Medical Center have identified neutral sphingomyelinase as a key player in the progression of Alzheimer's disease. By inhibiting this protein, they were able to prevent activated brain cells and beta-amyloid from killing neurons.
A study published by the American Academy of Neurology found that brain lesions associated with dementia contribute to mild memory loss in older adults. The study of 350 Catholic nuns and priests revealed a gradual decline in memory until the last four to five years of life.
A study published in Neurology found that mild memory changes are caused by brain lesions associated with Alzheimer's and other dementias, contradicting the long-held notion that age is a primary factor. The study involved over 350 participants and showed a rapid decline in cognitive function in the last four to five years of life.
A new study published in Neurology shows that mild cognitive impairment (MCI) is 1.5 times higher in men compared to women. MCI often leads to Alzheimer's disease and the study found nearly 14% of participants had MCI, with men being more likely to experience it.
A new study by Baycrest's Rotman Research Institute found that older adults are more prone to destination memory failures, including falsely believing they've shared information. They remain highly confident in these false beliefs, leading to awkward social situations and miscommunication.
A recent study published in the journal Brain has found a link between nerve cell production and memory in humans. The research suggests that increasing nerve cell regeneration in the hippocampus may alleviate or prevent memory loss, providing new insights into age-related cognitive decline.
A new study found that individuals with alcohol dependence not only experience impaired episodic memory but also a distorted perception of their own cognitive abilities. This distortion leads to an overestimation of memory capacities and a failure to recognize actual memory deficits.