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Science News Archive September 2001 - Page 4


Page 4 of 6

Genomes on 'chips' boon to cancer research

Researchers used DNA-coated microchips to discover that flavopiridol works by broadly inhibiting messenger RNA molecules, which are responsible for carrying genetic information to cellular protein factories. This inhibition ultimately leads to a halt in the production of certain proteins, allowing normal cellular processes to continue.

SourceBMC (BioMed Central)·JournalGenome Biology·DateSep 13, 2001

Black holes take the plunge

The Lazarus Team has made predictions for the gravitational waves emitted during black hole mergers, allowing for the first-ever detections. These simulations will provide astronomers with a set of templates to recognize signals in noise from detectors and deduce the masses and distances of the holes.

SourceMax-Planck-Gesellschaft·JournalPhysical Review Letters·DateSep 13, 2001

Pre-Neandertal humans developed social skills earlier than thought

Fossils from three different humans estimated to be about 175,000 years old show a stage of evolutionary development that led to the Neandertals. The jaw fragment reveals signs of reduced chewing force due to food preparation changes, suggesting extensive community support for individuals with difficulty caring for themselves.

SourceWashington University in St. Louis·JournalProceedings of the National Academy of Sciences·DateSep 12, 2001

Rethinking reverse cholesterol transport

Researchers reexamine the process of reverse cholesterol transport, a critical mechanism for removing excess cholesterol from peripheral tissues. The study reveals that this process may have both protective and detrimental effects on cardiovascular health.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateSep 12, 2001

Two routes to cell death in the diseased kidney

Researchers have discovered two distinct pathways leading to cell death in the diseased kidney, which could lead to new therapeutic targets for kidney disease. These findings provide a better understanding of kidney pathology and may enable the development of more effective treatments.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateSep 12, 2001

Alternative therapy use by Parkinson's patients

A new study reveals that many Parkinson's patients are using alternative therapies, despite a lack of physician knowledge on the topic. The research found no correlation between disease severity and use of alternative therapies, suggesting that patients are seeking these treatments for other reasons.

SourceJohns Hopkins Medicine·JournalNeurology·DateSep 10, 2001

Low sperm count linked to organic solvents

A study of over 1200 Canadian manual workers found that moderate occupational solvent exposure was associated with a significant increase in low sperm counts. Painters, decorators, and builders were at the highest risk, while glycol ethers are suspected to be hazardous to male fertility

SourceBMJ Specialty Journals·JournalOccupational and Environmental Medicine·DateSep 10, 2001

Phased-out Bt corn variety dramatically cut growth rate of black swallowtail caterpillars

Researchers found that black swallowtail caterpillars fed on Bt corn pollen experienced significant growth rate reduction, varying up to three times smaller in distance from the crop. The discovery suggests sublethal effects of Bt corn pollen on non-target species and emphasizes the need for careful event selection by producers.

SourceUniversity of Illinois at Urbana-Champaign, News Bureau·JournalProceedings of the National Academy of Sciences·DateSep 10, 2001

Gene therapy may be a tool to prevent blindness

Researchers have successfully used gene therapy to reduce new blood vessel growth by up to 90% in mice with conditions similar to macular degeneration and diabetic retinopathy. Two genes, endostatin and pigment epithelium-derived factor (PEDF), were injected into the animals' eyes or tails to demonstrate the potential of gene therapy a...

SourceJohns Hopkins Medicine·JournalAmerican Journal Of Pathology·DateSep 10, 2001

From embryo to placenta, gene transfer in primates a success

Researchers at the University of Wisconsin-Madison have made a breakthrough in gene transfer technology by inserting a jellyfish gene into rhesus monkey embryos, resulting in transgenic placentas that produce the desired protein. The study promises new insights into pathologies of pregnancy and has implications for human gene therapy.

SourceUniversity of Wisconsin-Madison·JournalProceedings of the National Academy of Sciences·DateSep 10, 2001

Increase in abnormal heart rhythms in shift workers

A recent study has found that shift workers are more likely to experience abnormal heart rhythms, with the risk increasing with the number of night shifts worked. The study measured changes in premature ventricular complexes and heart rate variability among employees working day and night shifts.

SourceBMJ Specialty Journals·JournalOccupational and Environmental Medicine·DateSep 10, 2001