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Science News Archive 2002 - Page 76


Page 76 of 93

Ace inhibitors could slow muscle decline

Researchers found that continuous ACE inhibitor users had a lower average decline in muscle strength and walking speed compared to intermittent users of other antihypertensive drugs. The study suggests that ACE inhibitors could be used to slow physical decline in elderly people without congestive heart failure.

SourceThe Lancet_DELETED·JournalThe Lancet·DateMar 14, 2002

Going beyond the genome

Researchers successfully determined the subcellular localization of over 2700 yeast proteins using a high-throughput method. By predicting the localization of all 6100 yeast proteins, Dr. Snyder and colleagues provided insight into nearly half of previously uncharacterized yeast proteins.

SourceCold Spring Harbor Laboratory·JournalGenes & Development·DateMar 14, 2002

Microtumor-induced vascular development

Glioma cells induce angiogenesis by interacting with host vasculature and sprouting new vessels, defying the cooptation model. Vascular outgrowth occurs as a continuous process of growth and remodeling, starting early in tumor progression.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateMar 13, 2002

Mayo Clinic news briefs

A Mayo Clinic study finds an association between estrogen status and reduced coronary calcium and plaque area, suggesting a potential benefit against heart disease. Estrogen may modulate the calcium content of atherosclerotic plaques, slowing progression of atherosclerosis in women.

SourceMayo Clinic·JournalJournal of Endocrinology and Metabolism·DateMar 13, 2002

Researchers capture unusual sprite-like blue jet

Researchers have captured an unusual sprite-like blue jet over Puerto Rico, exhibiting characteristics of both blue jets and sprites. The event's unique features include a branching conical shape and hot spots, which are similar to those seen in computer models but not fully explained.

SourcePenn State·JournalNature·DateMar 13, 2002

Oxidative damage to eNOS by tissue peroxynitrite

Research reveals that peroxynitrite damages endothelial NO synthase (eNOS), promoting uncoupled catalysis and oxidative stress in vascular tissues. This damage can propagate to other susceptible enzymes, exacerbating inflammation and oxidative stress.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateMar 13, 2002

U.S. forests may be products of pollution

New research suggests that unpolluted forests may exhibit more uniform nitrogen biogeochemistry than previously thought, with complex and idiosyncratic responses to human activities. This challenges long-held assumptions about the ecological function of forests near populated regions.

SourceOregon State University·JournalNature·DateMar 13, 2002

Seeing the universe in a brand new light

Researchers at Northwestern University have created a novel device that detects ultraviolet light 10 times more efficiently than the Hubble Space Telescope. The innovative detector uses gallium nitride material to block visible and infrared light, allowing astronomers to study important objects in the universe for the first time.

Alcohol researchers find genetic locus of human brain wave

Scientists have identified a specific genetic locus associated with fundamental human brain oscillations, contributing to the understanding of brain neuroelectric activity and providing new insights into alcoholism risk. The study found an association between beta EEG frequencies and a cluster of genes located on chromosome 4.

SourceNIH/National Institute on Alcohol Abuse and Alcoholism·JournalProceedings of the National Academy of Sciences·DateMar 12, 2002

'Back at square one' to find culprit in familial ALS

Researchers from Johns Hopkins Medicine found that removing copper had no effect on the pace of disease in mice with familial ALS-like paralysis. The study used CCS chaperone-deficient mice to rule out copper's role in the disease, suggesting alternative pathways may be responsible for the mutant enzyme's effects on motor neurons.

SourceJohns Hopkins Medicine·JournalNature Neuroscience·DateMar 12, 2002