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Science News Archive September 2007 - Page 17


Page 17 of 18

University of Alberta researchers find new cause of blindness

Researchers at the University of Alberta have found a new cause of blindness linked to a gene that regulates pH levels in the retina. The study suggests that targeting this process could lead to potential treatments for previously unknown causes of blindness, including hereditary vitreoretinal degenerations.

SourcePLOS·JournalPLOS ONE·DateSep 4, 2007

Study examines performance-based pay for teachers

A recent study by economists at the University of Missouri-Columbia and Vanderbilt University found that linking teacher pay to student achievement results in improved student outcomes. The researchers advocate for school districts to explore performance-based systems as a potential solution to increase teacher effectiveness.

SourceUniversity of Missouri-Columbia·JournalJournal of Policy Analysis and Management·DateSep 4, 2007

Burning extra calories with a 'futile protein cycle'

Researchers found that mice with a disrupted enzyme involved in protein metabolism became slimmer despite eating more food, showing improved glucose and insulin tolerance. The study suggests a new potential weight-loss therapy by manipulating protein turnover through pharmacological means.

SourceCell Press·JournalCell Metabolism·DateSep 4, 2007

A classic method for modeling skin cancer is featured in Cold Spring Harbor Protocols

Researchers have developed a protocol for generating mice with squamous cell carcinoma, allowing them to study the disease in a controlled environment. The method involves injecting mice with DMBA and TPA, leading to tumor formation and enabling scientists to examine the role of the immune system in susceptibility to skin cancer.

SourceCold Spring Harbor Laboratory·JournalCold Spring Harbor Protocols·DateSep 4, 2007

A call for action

The Lancet Global Mental Health Group urges governments, agencies, and donors to scale up mental health services worldwide due to inadequate treatment rates. The cost is estimated at $2-$4 per person in low-income countries, a modest investment compared to other global disease burdens.

SourceThe Lancet_DELETED·JournalThe Lancet·DateSep 3, 2007

How the plant immune system can drive the formation of new species

A study found that a mis-regulated plant immune system can establish reproductive barriers, potentially leading to speciation. Researchers discovered that hybrid necrosis, a syndrome affecting unfit hybrids, is caused by a common group of genes being more strongly or weakly active in the hybrids than in their parents.

SourcePLOS·JournalPLOS Biology·DateSep 3, 2007

Possible Hepatitis C vaccine

Researchers at Nottingham University have identified antibodies that can prevent infection with various strains of Hepatitis C virus in laboratory models. This breakthrough could lead to the development of a vaccine, which would significantly improve healthcare benefits for those suffering from hepatitis.

Knee arthritis link to lung cancer

Research found knee monoarthritis in 296 patients (4.4%) with rheumatic disorders, a rare condition associated with operable non-small cell lung cancer. The disease is challenging to treat unless caught early, and the discovery provides new insights into potential early warning signs.

SourceBMJ Specialty Journals·JournalAnnals of the Rheumatic Diseases·DateSep 3, 2007

Renal function and heart disease, and more

Researchers found a moderate increase in risk of coronary heart disease associated with very low estimated glomerular filtration rate, according to a new prospective study and systematic review published in PLOS Medicine. The study suggests that renal function may be an important factor in the development of cardiovascular disease.

SourcePLOS·JournalPLOS Medicine·DateSep 3, 2007

Rates of bipolar diagnosis in youth rapidly climbing, treatment patterns similar to adults

The study found that the number of office visits resulting in a bipolar disorder diagnosis for youths ages 19 and younger increased from 25 per 100,000 people in 1994-1995 to 1,003 per 100,000 people in 2002-2003. In contrast, adults saw a rise from 905 per 100,000 people to 1,679 per 100,000 people over the same period.

SourceNIH/National Institute of Mental Health·JournalArchives of General Psychiatry·DateSep 3, 2007

Flies can turn off their immune response

Researchers found that flies have a complex immune system regulated by AP-1 and STAT transcription factors, which edit and repress the immune response to prevent 'friendly fire'. This mechanism is evolutionarily conserved to maintain balanced immune responses.

SourcePLOS·JournalPLOS Biology·DateSep 3, 2007

First individual genome sequence published

Researchers at JCVI have published the first true diploid genome from one individual, Craig Venter's, covering over 2.8 billion base pairs. The study reveals high genetic variation between two chromosomes within an individual and uncovers a total of 4.1 million variants, including 3.2 million SNPs.

SourcePLOS·JournalPLOS Biology·DateSep 3, 2007

Auto immune response creates barrier to fertility; could be a step in speciation

Researchers at the University of North Carolina and Max Planck Institute discovered that an autoimmune response can create a barrier to producing viable offspring in plants. This phenomenon, known as hybrid necrosis, can be triggered by specific gene combinations, suggesting a potential early step in the development of new species.

New approaches to reduce scarring

Researchers examine hypertrophic scar formation, current treatments, and promising research areas to advance the field. Current treatments for hypertrophic scarring are estimated to cost at least $4 billion annually in the US.

SourcePLOS·JournalPLOS Medicine·DateSep 3, 2007

Protecting our beaches

A new risk assessment tool has been developed to help reduce the transfer of disease-causing bacteria from farmed environments to watercourses. The expert-weighted risk tool identifies fields and farmyards with the greatest likelihood of contaminating waterways, allowing farmers and landowners to prioritize clean-up efforts.

Choosing a mate: what we really want

A study published in the Proceedings of the National Academy of Sciences found that humans tend to choose mates based on physical attractiveness, with men prioritizing looks and women valuing security and material stability. The research, conducted via speed-dating sessions, suggests that this preference is rooted in evolutionary theory.

SourceIndiana University·JournalProceedings of the National Academy of Sciences·DateSep 3, 2007