A team of researchers developed a 'nano cocktail' consisting of two nanomaterials that work together to locate, adhere to, and kill cancerous tumors. The system uses gold nanorods to accumulate in tumors and then sends in a second nanoparticle type coated with a targeting molecule specific for the heat-treated tumor.
A U-M study reveals that a specific receptor, CXCR1, triggers growth of breast cancer stem cells in response to inflammation and tissue damage. Researchers found that blocking this receptor using an existing anti-inflammatory drug repertaxin kills breast cancer stem cells and prevents metastasis in mice.
A national survey found that only 21% of Americans with clinical depression receive adequate treatment, while half go untreated. Disparities in mental healthcare access persist, particularly for African Americans and Mexican Americans, who face significant barriers to care.
Professor Alan Cowman's research on Plasmodium falciparum has led to a better understanding of the malaria parasite's evasion of the human immune system and its invasion of red blood cells. He is being recognized for his contributions to identifying vaccine and drug candidates against malaria.
A study of over 15,659 adolescents found that those with earlier parental set bedtimes were less likely to suffer from depression and suicidal ideation. The association was most pronounced among adolescents who slept for five hours or fewer per night.
A study published in Sleep found that older men with restless leg syndrome (RLS) were more likely to experience erectile dysfunction. The association between RLS and erectile dysfunction was independent of other risk factors and was linked to hypofunctioning of dopamine in the central nervous system.