A new GSA report emphasizes the critical role of primary care providers in detecting and managing cognitive decline, with a focus on actionable insights for clinicians. The report highlights advances in diagnostic technology and modifiable lifestyle factors linked to brain health outcomes.
Researchers at the University of Illinois Chicago have developed a new imaging method that allows scientists to see previously hidden enzyme activities in small regions across the whole cell. The technique, dubbed Fluctuation Increase Negated by Intra-Chain (FINICI), flips the optical readout of negative biosensors into positive, reada...
Researchers discovered a previously unknown damage mechanism in metals under shear loading, where stiff particles inhibit material movement and boost void growth. The study used synchrotron computed laminography and 3D simulation methods to investigate an aluminum alloy and found significant damage growth up to sixfold.
The study creates a radiohybrid approach that labels a single molecule with two different diagnostic radionuclides, enabling long-term visualization of therapeutic agent distribution. This allows for personalized cancer medicine by calculating optimal radiation doses for individual patients.
A new study found that honey bee larvae lack the sophisticated olfactory capabilities of adult honey bees. Adult bees have a suite of chemosensory receptors, including olfactory receptors and ionotropic receptors, essential for detecting odors from potential sources of pollen and nectar.
A Tel Aviv University study proposes that the Qumran sect used a 364-day calendar for over two decades before abandoning it due to its mathematical imperfection and improved relations with Hasmonean leadership. The calendar's daily deviation from the astronomical year accumulated rapidly, posing practical problems for the community.
A new AI-based system called ShadowSense learns from real-world data to predict short-term changes in solar module power output. The system outperforms conventional methods with an accuracy rate of over 92%, providing valuable insights for electricity grid management.
Threats to academic freedom are increasing, including attacks on individual researchers and specific fields of study. Research vulnerabilities can be strengthened through cooperation among scientists, businesses, and civil society.
A review of hundreds of studies suggests that polyphenol-rich foods like berries, tea, and olive oil may support healthy brain aging by reducing inflammation and promoting nerve cell function. While no single food can prevent Alzheimer's disease, a balanced diet rich in plant-based foods may help preserve cognitive function over time.
New research highlights that modern slavery is often a result of business decisions prioritizing cost and efficiency over labor conditions. Companies must invest in understanding their supply chains to tackle exploitation and shift focus from reporting to knowledge.
New research shows that tadpoles adapt their diet in response to rising temperatures, consuming more plant material and eating overall. However, this natural strategy becomes less effective as temperatures continue to rise, with consequences for growth, development, and survival.
A new study found that adults with disabilities have more than three times the rate of alcohol use disorder diagnoses compared to adults without disabilities in the US. Adults with serious mental illness and acquired brain injuries had the highest rates of AUD, with men with disabilities having the highest rates.
Researchers at the Netherlands Institute for Neuroscience are working to understand how the brain regulates stress and developing new treatments for conditions like PTSD and anxiety disorders. They aim to identify brain regions that can be targeted to teach people to better control their stress responses through neurofeedback.
A qualitative study reveals that watchdog science journalism is labour-intensive and time-consuming, with high thresholds of evidence and significant barriers to access. The findings highlight the need for media organisations to protect specialised investigative work and foster a more transparent public discussion about science.
Researchers discovered a new signaling pathway allowing plants to adjust protein production in minutes, not hours. Short sequence elements in messenger RNA act as molecular switches, enabling direct regulation of protein synthesis.
A new 3D computer model developed by the University of Surrey has shown how Pseudomonas aeruginosa grows and spreads its protective layer under constant fluid flow. The model's accuracy was validated through laboratory experiments, demonstrating potential for faster and smarter ways to understand bacterial behavior.
A new species of harvester ant, Messor odrysarum, has been discovered in the Eastern Rhodopes region of Bulgaria. The species is part of the Messor genus and has distinctive physical traits compared to its close relatives.
The partnership generates valuable bathymetric data through vessel operations and lost crab trap removal, enhancing navigational safety and coastal models. The new dataset will be publicly available for researchers, agencies, and coastal managers to support commerce.
A new study published in Hepatobiliary Communications reveals that standard CT scans can detect stage-specific tissue patterns predicting severe liver complications in chronic hepatitis B-related cirrhosis. Visceral fat and muscle shifts carry different warning meanings based on the patient's disease stage.
Researchers identified a new biological vulnerability in KMT2A-rearranged B-cell acute lymphoblastic leukaemia, which could lead to more effective treatments. Blocking the interaction between two proteins slowed leukaemia progression and enhanced conventional treatment efficacy.
A global study found that plant evolutionary history plays a stronger role in shaping nonstructural carbohydrate (NSC) storage than current environmental conditions. NSC variability is organ-specific, with leaf NSCs increasing toward higher latitudes and stem and root NSCs declining.
The proposed OMB rule change would fundamentally alter how federal research funding is allocated in the US, compromising research independence and restricting international collaboration. PLOS argues that costs linked to making research available should be assessed against public and economic value, rather than being unallowable.
A world-first lens has been developed to focus neutrons into a single focal point, overcoming the challenge of defocusing weakly interacting particles. This allows for high-resolution imaging with a resolution below twenty micrometers, opening up new possibilities for materials science and device analysis.
A joint KAIST–University of Tokyo research team found that temperature-related suicide mortality is expected to rise globally due to climate change. Regional differences in future rises are driven by varying temperature-suicide relationships, with East Asia and South America projected to see relatively small increases.
A new review framework redefines how hard carbon anodes are engineered in sodium-ion batteries. By optimizing each stage of the fabrication chain, researchers achieve improved performance and reduced costs.
Scientists are conducting a European clinical trial aiming to reduce antibiotic use and lower recurrent urinary tract infection rates by targeting pathogenic E. coli strains with CRISPR-enhanced phage cocktails and microbiome restoration therapies.
The Netherlands Institute for Neuroscience launches a grant programme to support joint research projects between fundamental neuroscience and clinical psychiatry. The aim is to improve understanding of brain changes in psychiatric disorders, paving the way for more accurate diagnoses and targeted treatments.
Researchers at Nagoya University review the latest results of plasma agriculture, finding that well-tuned plasma treatments boost seed vigor or yield in over two-thirds of studies. Plasma-induced epigenetic changes also promote positive expression of plant genes involved in germination and stress tolerance.
The integration of biomass-derived materials provides an innovative solution to overcome the limitations of solid-state batteries, including high fabrication costs and environmental footprint concerns. By repurposing natural structures, researchers have discovered structurally sophisticated biopolymers that possess naturally hierarchic...
Researchers at Technion-Israel Institute of Technology discovered that mature, aged cells can revert into active stem cells that regenerate damaged tissue. This finding challenges the prevailing view on tissue regeneration and implies the possibility of therapies promoting natural healing mechanisms.
The Japan Institutional Gateway platform is now available to researchers across Japan, enabling the publication of Japanese-language research at world-class speed and reliability. This expansion aims to support the acceleration of the open research movement promoted by the Japanese government.
A study from Binghamton University found that poor sleep quality is connected to hyperarousal in young people and neurodegenerative patterns among older women. Research analyzed brain scans from over 1,300 participants to see how brain networks connect at rest in those with poor sleep.
Researchers from Fuzhou University review the potential of Atomic Layer Deposition to regulate interfacial chemistry in zinc-ion batteries, enabling durable high-performance systems. The technique's unique conformality and precision make it suitable for layer-by-layer growth of atomic films on complex battery components.
Researchers found ulinastatin significantly exerts hepatoprotective effects by inhibiting cytokines, reducing cell death and oxidative stress, and regulating immune function. It also adjusts enzyme activity involved in blood clotting and fibrinolysis system, showing potential as supportive treatment for liver diseases.
A sustainable management model is proposed for the Duernas Saltworks to preserve its geological heritage, cultural landscape and support rural development. The model aims to balance conservation, artisanal production and community engagement.
The Three Gorges region recorded its second-hottest year on record in 2025, with an average temperature 1.1°C above normal, and the most extreme autumn rainfall in 43 years. Persistent heatwaves and torrential rains caused widespread flooding and posed new challenges for disaster prevention and engineering project safety.
Researchers developed an ultrasensitive electrochemical biosensor to detect early-stage liver fibrosis using only a small amount of blood, providing a non-invasive diagnosis method. The sensor achieved high sensitivity and accuracy, distinguishing between healthy individuals and patients with 95.24% sensitivity and 100% specificity.
Research found that severe workplace violence incidents are concentrated in busy daytime periods, outdoor activities, and specific ward areas. The study suggests that everyday ward routines, situations, and environmental factors contribute to the risk of workplace violence.
Researchers developed a novel dual-frequency fiber-array photoacoustic computed tomography (PACT) technology, enabling high-resolution imaging of the entire brain and centimeters deep. This innovation overcomes the limitations of conventional PACT systems, allowing for precise functional imaging and metabolism assessment.
Researchers have discovered a complex layering system around phytoplankton cells, with water-repellent substances concentrated near the surface. This finding has significant implications for models of interactions between phytoplankton and bacteria, and could improve our understanding of the oceans' carbon cycle.
Researchers discovered bio-metals in the jaws of ancient sea worms, exhibiting properties like hardness and strain mechanics. The unique materials show similarities to metals but also have distinct mechanical properties.
A study found that nearly half of preterm children did not meet expected attainment levels in writing and maths by age 6-7, while social deprivation and maternal smoking during pregnancy are linked to lower attainment. Strategies to address social inequalities and support preterm children are vital to improve outcomes.
Researchers investigated hantavirus infection's neurological effects, finding that they can be severe and uncommon. The study aims to improve understanding of the pathophysiology, identify therapeutic targets, and develop management guidelines for these manifestations.
Experts recommend implementing safer technologies and modernizing radiation safety standards to reduce preventable radiation exposure and orthopedic injuries. The consensus statement emphasizes the need for mandatory action to prioritize protecting healthcare workers, ensuring a healthy workforce for patients' access to lifesaving care.
A cohort study reveals that colorectal cancer treatment delays are associated with increased metastasis risk. This finding highlights the need for integrated care and tailored benchmarks for treatment initiation to improve timely and equitable care.
AI model improves cardiac MRI interpretation, while immersive VR simulators aid poststroke rehabilitation. Meanwhile, menopause tracking apps offer empowerment but also pose risks due to inaccurate information and targeted marketing.
Researchers found that colossal karst sinkholes help preserve the rare Magnolia aromatica tree while limiting gene flow and diminishing its long-term evolutionary potential. The study suggests that conservation strategies should protect both individual habitats and connections among populations.
The study found associations between mitochondrial heteroplasmy and cardiometabolic parameters in patients with metabolic syndrome. Intermediate heteroplasmic mutations were associated with the degree of vascular stenosis and lipid metabolism parameters.
Researchers developed a prototype device that autonomously synchronizes distant qubits using a common source of correlated light particles, confirming a 20-year-old prediction. The approach requires no active control or measurement, making it fully autonomous and potentially boosting quantum technology.
Researchers propose a new perspective on ARDS pathogenesis, arguing that multiple forms of regulated cell death communicate through extensive molecular crosstalk. This crosstalk collectively drives lung inflammation and respiratory failure, highlighting the need for network-based therapeutic strategies.
Researchers are developing an AI-driven controller for hybrid microgrid systems that integrates multiple energy sources and storage systems. The system aims to increase efficiency of electrical grids used for data centers and other mission-critical loads.
Hepatocellular carcinoma (HCC) gene signatures can predict prognosis and respond to immune checkpoint inhibitors. However, validating these signatures across different platforms and overcoming ethical concerns hinder their widespread adoption. Integrating multi-omics approaches with liquid biopsy holds promise for personalized therapy,...
Researchers successfully acquired diagnostic X-rays in space, expanding crew health capabilities and paving the way for mission-critical non-medical tasks. The study found that portable X-ray machines are feasible in space, with no significant differences in image quality between pre-flight and inflight images.
A recent study from the University of Cambridge predicts that space launch costs will plummet over the next few years, falling more than 90% by 2040. The cost of sending a kilogram of payload into low Earth orbit is expected to drop from $3,868 last year to as little as $273 per kilo by 2040.
A study published in Anesthesiology found that nerve blocks do not cause nerves to become more sensitive or lead to worse pain after the block wears off. The researchers suggest that rebound pain is caused by the return of surgical pain as the block resolves, rather than hypersensitivity. This finding supports the continued use of nerv...
Researchers discover that emerging tick-borne viruses can escape the human immune system by producing enzymes that remove proteins attached to human proteins, rendering them undetectable. This finding has significant implications for developing a surveillance system to monitor these viruses and potentially mitigating large outbreaks.
A team of scientists has created a method to identify mineral biosignatures on other worlds using Raman spectroscopy. The technique uses machine learning to analyze features of the spectrum, such as band positions and intensities, to determine whether a mineral was formed biologically or abiotically.
A new study from UT San Antonio finds that emergency call takers' word choice can predict depression and anxiety symptoms, while positive expressions are often suppressed in high-stress professions. The research uses natural language processing to evaluate the psychological well-being of a critical but under-researched workforce.
Research by Cornell University found that China's efforts to improve water quality led to a 58% drop in agricultural value added and reduced hiring of agricultural workers in upstream counties
Rocket launch costs have decreased by 21.2% for every doubling of cumulative payload sent to orbit, driven by technological learning. By 2040, costs could reach $300 per kilogram, with SpaceX's Starship potentially pushing costs below $1,000.