Scientists at the University of Surrey have created ultra-sensitive nanofiber-based sensors that can harness power from gentle movements, enabling continuous and maintenance-free sensing. These breakthrough sensors have potential applications in sleep disorder monitoring and dementia care.
Research at the University of Colorado Anschutz Linda Crnic Institute found significant alterations in liver metabolism among individuals with Down syndrome, including elevated bile acids and biomarkers of liver dysfunction. The study suggests that dietary interventions may help improve health outcomes.
Researchers are expanding options for patients with hard-to-treat cancers using a personalized approach that identifies effective therapies by testing large libraries of drugs on living tumor cells. The approach has shown stronger responses than initial findings, suggesting it can reveal opportunities missed by traditional methods.
Researchers used CT scans and AI to find links between poorer abdominal muscle measures and higher incidence of falls in middle-aged adults. Maintaining good core strength throughout adulthood may provide benefits that start in midlife and continue into older adulthood.
Researchers used game theory and individual-based models to show how attack and defense strategies emerge as stable patterns, providing a theoretical framework for understanding predator–prey interactions. The study highlights the importance of sensory abilities for survival and challenges traditional views of predator-prey relationships.
New study finds that progenitor cells in the brain continuously produce new myelin-producing oligodendrocytes, despite being inefficient. This process suggests that treatments harnessing their developmental aspects may increase rapid myelin repair for demyelinating diseases like multiple sclerosis.
Researchers use ground-based seismic sensors to detect sonic booms from reentering space debris, estimating its trajectory, size, composition, and potential impact locations. The approach was tested on the Shenzhou-15 orbital module's reentry, revealing a progressive fragmentation pattern that matched eyewitness reports.
The Käte Hamburger International Centre will study messianic figures and discourses throughout history, aiming to understand their impact on democracies and promote critical awareness. The centre plans initiatives in schools and educational settings to educate students about recognising messianic phenomena.
A new study shows that China can significantly limit its cooling-related climate impacts by transitioning to cleaner refrigerants and adopting high-efficiency cooling technologies. This integrated approach could phase down cumulative HFC consumption by 12.6 Gt CO2e from 2022 to 2060, avoiding up to 0.015°C of global warming.
A study published in PLOS Biology found that males rate computer-generated figures with a larger penis as more intimidating and sexually competitive. Women also prefer taller, more V-shaped males with a larger penis, but beyond a certain point, further increases in size have diminishing benefits.
Researchers at Tohoku University's WPI-AIMR propose Harvested Reservoir Computing framework that harnesses road traffic dynamics for energy-efficient AI systems. The approach yields better prediction accuracy before congestion begins, reducing computational overhead and energy consumption.
A 5,500-year-old Treponema pallidum genome from Colombia sheds light on the emergence of syphilis, suggesting its origin was linked to social and ecological conditions of hunter-gatherer societies rather than agricultural intensification. The study's findings expand our understanding of treponemal diseases worldwide.
Research by Université Laval found that physical exercise and living in favorable conditions reduce depression risk by maintaining blood-brain barrier integrity. Fgf2 protein plays a key role in this mechanism and may serve as a biomarker for mood disorders.
Researchers at Heriot-Watt University have developed a method to remove unwanted tissues, such as tumors, with high precision using deep-ultraviolet lasers. The study demonstrates 10-micrometre precision with no detectable collateral damage.
Researchers have developed an efficient biosynthesis method for medicarpin in engineered yeast. The study involved the coordination of multiple metabolic pathways to produce high yields of medicarpin, overcoming supply chain and sustainability challenges associated with conventional methods.
A new preventive intervention called REconnect has been developed to reduce loneliness among university students. The program aims to strengthen social ties and inclusion before loneliness becomes chronic, with encouraging results showing increased life satisfaction and reduced loneliness.
The Assessing Genetic Diversity in Africa (AGENDA) project has generated whole-genome sequence data from over 1000 individuals from underrepresented communities, aiming to correct the imbalance in global genomic datasets. This effort will help predict disease risk and tailor treatments more effectively for African populations.
The JEDI Draghi Tracker measures Europe's implementation of the Draghi report on competitiveness, focusing on 20 impactful measures. Currently, only 14% has been implemented after 15 months.
The study found that women in agriculture suffer more from rising temperatures, while simple home modifications such as white-painted roofs and insect screens improved living conditions. The results are also relevant for adapting to climate change in Germany, with a focus on affordable and sustainable measures.
The University of Texas MD Anderson Cancer Center has made significant advancements in cancer care through its collaborative efforts between clinicians and scientists. These breakthroughs include an immune-targeting vaccine that shows promise in intercepting cancer in patients with Lynch Syndrome, a novel immunotherapy that demonstrate...
Malicious AI swarms can generate vast amounts of persuasive content, infiltrate online communities, and create adaptive campaigns that harm democratic discourse. The authors propose a distributed 'AI Influence Observatory' to guide independent oversight and action.
The Center for AI Responsibility and Research will build upon Binghamton research advancing AI for the public good. The new center is supported by a $30 million commitment from Tom Secunda and $25 million from Gov. Hochul and the NY State Legislature.
Researchers discovered that endogenous retroviruses play a crucial role in early human embryo development. These genetic remnants of ancient viral infections help drive the activation of genes required for successful development, with reduced expression leading to impaired zygotic genome activation and embryo arrest.
The report shows a notable increase in medication treatments, such as chemotherapy, immunotherapy, and hormone therapy, used before surgery to treat many cancers. Neoadjuvant systemic therapy increased notably for certain cancers, including gynecologic cancers, pancreatic cancer, and rarer abdominal lining cancers.
Researchers developed a new bioinformatic framework to reconstruct polyploid genome evolution, applying it to the cultivated octoploid strawberry. The approach identifies subgenome structure and infers the timing of major genome-merging events, clarifying debates about the evolutionary origin of modern strawberry.
Researchers have found that teosinte-derived traits in corn can alter the relationship between plants and soil microbes, improving nitrogen cycling and potentially making corn production cheaper. By reintroducing these traits, modern maize becomes more sustainable.
Researchers use seismic data to pinpoint the trajectory of falling debris, providing near-real-time tracking and rapid retrievals. This innovation complements radar data and can help locate potential crash sites, retrieve hazardous objects, and mitigate environmental risks.
A new study published in Otolaryngology–Head and Neck Surgery found that GLP-1R agonists are associated with reduced need for revision sinus surgery and biologic therapies in obese patients. The study analyzed data from over 100 million patient records and showed a 36% reduction in revision surgery rates at one-year follow-up.
Researchers have successfully controlled the rotation of molecules suspended in liquid helium nano-droplets using a new optical centrifuge. This breakthrough enables scientists to study the behavior of exotic, frictionless superfluids and understand how molecules interact with the quantum environment at various rotational frequencies.
A study published by the National Institutes for Quantum Science and Technology found that carbon-ion radiotherapy provided durable tumor control with minimal side effects while preserving breast appearance in carefully selected patients who were unable or unwilling to undergo surgery. The treatment resulted in excellent local control ...
A new global dataset quantifies biodiversity loss in international trade of staple crops, revealing a strong upward trend and key contributors. Soybean trade shows the most rapid increase, surpassing wheat, while major agricultural producers drive global biodiversity loss patterns.
The new process generates formate and hydrogen from glycerol through electrolysis, producing only CO2-neutral formates when powered by green electricity. The method uses an innovative copper-palladium catalyst, which could contribute to the electrification of the chemical industry.
Researchers at the University of Arizona have developed a copper-based compound that can kill MRSA bacteria by disguising itself as iron. The compound, BMDC, works by delivering a toxic dose of copper to bacterial colonies, making it an effective treatment against drug-resistant infections.
Researchers developed a new method to predict how cancer cells evolve by gaining or losing whole chromosomes, mapping favorable or harmful changes. ALFA-K quantifies how whole-genome doubling helps cancer cells survive high levels of chromosomal instability, laying the groundwork for evolution-aware approaches to cancer treatment.
Researchers found that activating specific healing pathways in fibroblasts from facial tissues can lead to regenerative wound healing with reduced scarring. This study could lead to new treatments for scar formation and its associated complications, including chronic pain and disease.
A new study from the Universities of Bath and Waterloo finds that people are more emotionally affected by anticipating negative future outcomes than positive ones, shaping economic behaviour. Individuals with stronger negative anticipatory emotions are more likely to avoid risk and less willing to wait for delayed outcomes.
Research from Goethe University Frankfurt reveals that many zoo mammal populations are becoming demographically fragile due to declining birth rates and increasing numbers of older individuals. This trend poses a threat to species conservation goals, as stable and resilient populations are crucial for addressing biodiversity loss.
Salk Institute scientists discover that dietary supplementation of the amino acid methionine protects infected mice against inflammation-related wasting, blood-brain barrier dysfunction, and death. Methionine boosts kidney filtration, reducing circulating cytokine levels and improving disease outcomes.
The event highlighted urgent global risks and science-led solutions for antimicrobial resistance, trust in data, and AI-enabled sustainable cities. Experts emphasized the need for immediate actions against AMR, which could kill more people than cancer by 2050.
Mangroves in tropical countries are being overwhelmed by land- and sea-based waste, posing a significant threat to environmental balance, biodiversity, and human well-being. The study highlights the urgent need for measures to reduce single-use plastic packaging to mitigate this problem.
A research team has demonstrated how quantum mechanical entanglement can be used to measure several physical parameters simultaneously with increased precision. By distributing atoms into up to three spatially separated clouds, the effects of entanglement act at a distance, reducing measurement uncertainties and canceling disturbances.
Physicists at University of Jyväskylä create long-sought two-dimensional topological material, exceeding 0.2 eV band gap and exhibiting topological edge states protected by crystal lattice symmetry. The strain-tunable material enables future advances in spin-based electronics and nanoscale devices.
Scientists at UNIGE created an AI tool called MangroveGS that can accurately predict the risk of cancer metastasis and recurrence. The algorithm uses gene expression signatures from colon cancer cells to identify key factors influencing metastatic potential, paving the way for more precise care and discovery of new therapeutic targets.
Researchers found that individuals with Alzheimer's disease have reduced brain complexity in response to magnetic stimulation compared to healthy controls. This suggests that brain stimulation may be used to evaluate the integrity of conscious processing in people with AD.
A new study reveals that around one-third of all newly written software functions in the United States are already being created with AI support, with productivity gains mainly driven by experienced developers. The study found wide regional gaps, with the US leading at 29% AI-assisted code, while China and Russia lag behind.
Researchers have created validated tools to measure 'woke' attitudes on the political left and right. The study, published in Scandinavian Journal of Psychology, used a survey with over 600 respondents from Finland to test the scales.
Researchers found that particulate matter concentrations in Sarajevo exceed WHO recommended daily limits, with wood-burning stoves contributing to organic pollution. Sulphur dioxide emissions from old power plants also impact air quality, with the city's valley experiencing rapid pollutant drop at night.
Researchers explore polyherbal formulations combining multiple plant extracts to combat skin aging, featuring seven key plants with their bioactive phytoconstituents. These formulations offer a synergistic advantage, enhancing efficacy while reducing toxicity risks associated with single compounds.
Cancer mortality rates have decreased for breast cancer and leukemia, despite increasing incidence, while colorectal cancer has become the leading cause of death among US young adults. Colorectal cancer surpasses lung, breast, and prostate cancers as the leading cancer-related death in people under 50 years old.
A new study reveals that gut microbiota directly affects intestinal stem cell function, leading to impaired regeneration after injury. Restoring a more youthful microbiota can reverse the age-related decline in ISC activity.
Skin pigmented spots feature immune cell infiltration, branched blood capillaries, and a disrupted skin barrier, necessitating innovative skincare strategies. The study highlights the need for multi-action ingredients that soothe inflammation, normalize blood vessels, and maintain a healthy skin microbiome.
Commercially insured patients frequently bypass rural hospitals between 2012 and 2021, generating large payments for receiving hospitals. The findings highlight the need for addressing this issue to alleviate financial distress on rural healthcare facilities.
Researchers propose a new conceptual framework for neutrophils, highlighting their dynamic and adaptable nature. The study reveals neutrophils' functional diversification and immunological memory capabilities, opening avenues for innovative therapeutic strategies.
A study reveals that expanding existing mines worsens environmental and social risks over time, with many operations concentrated in high-risk contexts. The practice tends to draw less regulation due to its routine nature, unlike new mining projects.
A new study finds that soil salinization influences inorganic carbon storage, particularly in regions with elevated salinity. The research reveals a conditional relationship between salinity and inorganic carbon, highlighting the need to incorporate soil chemical processes into global carbon assessments.
The ISSCR has released a comprehensive roadmap for developing pluripotent stem cell-derived therapies, outlining critical scientific, manufacturing, and regulatory guidance. The Best Practices document provides a risk-based, end-to-end development strategy to support informed decision-making across seven essential areas.
Research published in Scientific Reports found that ancient giant kangaroos could withstand the strain of hopping due to robust hindlimbs. The study's findings suggest that these animals were unlikely to rely solely on hopping for locomotion over longer distances, but may have used short bursts of hopping to evade predators.
A retrospective study of 161 cases found that dermatofibrosarcoma protuberans (DFSP) of the head and face favors the cheek region, particularly in older patients. The dominant site accounted for 65.38% of all head-and-face DFSPs, suggesting regional anatomic or biological factors influence tumor development.
A new USC white paper reveals that PBMs' reported profit margins are influenced by accounting practices, making it challenging for policymakers to understand the true cost drivers. The researchers suggest requiring financial transparency from PBMs to develop a better picture of their operations and costs.
Scientists studying giant fossilized kangaroos discovered that they could still hop, contradicting previous beliefs. The analysis of foot bones and ankle tendons revealed that these prehistoric kangaroos had adapted differently to manage their enormous size, enabling them to bounce.