A study published in Obstetrics & Gynecology found that high malpractice premiums are affecting the supply of obstetricians, particularly in states with the highest costs. Researchers found a significant increase in births-per-junior fellow in high-premium states compared to low-premium states.
A study found that nearly all US physicians in six high-risk specialties reported practicing defensive medicine, with common practices including ordering unnecessary tests and referring patients for consultation. Defensive medicine may reduce access to care and pose risks of physical harm, particularly in women's health.
Researchers at U-M have identified a method that produces viable eggs when thawed, allowing cancer patients to preserve fertility. The vitrification technique enables 98% survival of eggs after thawing, compared to traditional slow-freeze techniques.
Researchers investigated the role of genital neurological integrity and found that almost half of women with female sexual dysfunction (FSD) reported symptoms. Decreased sensation in the clitoris was particularly prevalent among those with multiple forms of FSD.
A study of 225 women undergoing IVF found that side-stream smoking was associated with lower implantation and pregnancy rates compared to non-smoking and mainstream smoking groups. The researchers are calling for women to reduce or prevent exposure to cigarette smoke, especially when trying to conceive.
A study led by Daniel W. Cramer found that high blood levels of antibodies against MUC1 protein are associated with lower incidence of ovarian cancer. These events include bone fractures and gynecological surgeries, suggesting a potential link between immune system activation and cancer protection.
Researchers at Yale University have developed a new blood test for ovarian cancer screening using four biomarkers, showing high sensitivity and specificity. The test predicts cancer in patients whose levels of two or more biomarkers fall within a certain warning area.
A study of over 900 primary care residents found that they feel unprepared to counsel patients on depression, substance abuse, and domestic violence. While most felt confident in discussing smoking and diet/exercise, gaps in training remain.
A study by University of North Carolina researchers finds that routine episiotomy during childbirth does not reduce pain or prevent complications, but may cause more harm. Women who underwent the procedure were more likely to experience urinary and fecal incontinence, pelvic organ prolapse, and impaired sexual function.
Researchers have successfully developed human eggs from ovarian surface cells (OSE cells) in a laboratory setting. This breakthrough has potential applications in human reproduction, including increased chances of conception for women with reduced fertility and premature menopause.
Researchers found a unique organization of inputs on hypocretin neurons in mice, where excitatory nerve junctions outnumber inhibitory contacts by almost 10 fold. Stressors like fasting excite these neurons, leading to insomnia and associated metabolic disturbances, including obesity.
Research found low doses of BPA in female rats inhibit estrogen-induced synaptic connections, affecting hippocampal development and memory. High concentrations of BPA have been reported in pregnant women's blood, potentially impacting human hippocampal development and long-term effects on children's learning ability.
A study published in Epidemiology found that women with a history of preeclampsia are at a two-fold risk of death compared to those without the disorder. Women diagnosed with preeclampsia who had a subsequent normal birth were also found to have a significantly increased risk of dying after 20 years of follow-up.
Researchers discovered that low levels of protein Z and S early in pregnancy can increase the risk of pregnancy complications. The study included 103 women with normal pregnancies, 106 with pregnancy complications, and 20 with inherited clotting conditions. Women with prior complications may be at higher risk for future issues.
Research found that Viagra increased fetal weights to normal values and completely prevented fetal resorption, suggesting beneficial effects on maternal uterine vascular adaptation and fetal health. The study's selective effect on the uteroplacental circulation avoids complications of antihypertensive therapy during pregnancy.
Scientists have successfully grown functional fat cells in a laboratory using a new microscopic three-dimensional scaffolding. The discovery may lead to breakthroughs in treating type II diabetes and could provide a source of transplantable organs.
A study found that 76% of women would be willing to accept a cervical cancer vaccine for themselves, while 67% of mothers with daughters would consent to have their child vaccinated. The main reasons for non-acceptance were unknown side effects and the belief that minors are not sexually active.
A recent study found that pregnant women who engaged in regular exercise had improved mental health and reduced symptoms of depression. The research suggests that moderate exercise, such as 30 minutes a day, can help counteract the negative effects of pregnancy on physical and mental well-being.
A new algorithm calculates the ratio of three specific proteins in urine and blood to identify severe preeclampsia with high sensitivity and specificity. This approach may provide a more accurate diagnosis than current tests, which can be confusing and lead to premature birth.
Researchers identified protein biomarkers in amniotic fluid linked to preterm labor, predicting success of cervical stitching. The study also found additional biomarkers suggesting other causes of preterm birth.
A large US study confirms that prior caesarean section does not increase the risk of future stillbirth. The research used a massive dataset of over 250,000 patients and found no association between prior caesarean delivery and increased risk of stillbirth.
A study published in American Journal of Obstetrics and Gynecology reveals that metabolic profiling can accurately identify patients at risk for preterm delivery. The method has shown a high degree of accuracy in identifying patients across different clinical groups, offering new hope for predicting the course of preterm labor.
Current clinical practice identifies only half of infected mothers, highlighting the need for systematic screening. Screening can detect infection early, preventing severe eye and brain damage in infants.
Researchers have developed a novel method called MR scoring to rapidly detect preterm birth from inflammation and infection in women. The test uses biomarkers Human neutrophil defensin 1, Human neutrophil defensin 2, Calgranulin C and Calgranulin A to identify women at risk of premature delivery with high sensitivity and specificity.
Researchers estimate that progesterone therapy could reduce the rate of recurrent preterm birth in the US by about 2%, preventing around 10,000 premature births annually. The study's findings are based on a clinical trial showing a significant reduction in preterm birth risk among women with a history of spontaneous preterm birth.
Researchers uncover key mechanisms behind puberty, revealing that a specific gene and protein interact to trigger hormone secretion. The study provides new insights into human development and may help prevent precocious or delayed puberty.
A study of 150 subjects found that listening to a relaxation tape prior to and during mammography did not decrease women's feelings of pain and anxiety. In fact, virtually none of the participants experienced pain or anxiety during the test, contradicting previous studies that attributed non-compliance to pain.
Researchers at Beth Israel Deaconess Medical Center have developed a simple urine test to detect preeclampsia risk in pregnant women. Urinary PIGF levels drop prior to preeclampsia symptoms, predicting which women will develop the condition.
Researchers have developed a new treatment that significantly reduces morphine use after hysterectomies, leading to improved lung function and more consistent pain relief. The treatment combines two non-opioid drugs, gabapentin and rofecoxib, which work together to alleviate movement-related pain and promote better breathing.
A study using a birthing simulator found that turning the baby so its spine faces the mother's belly requires less force and stretching on the baby's nerves than other techniques. This method can help reduce the risk of injury to babies during complicated deliveries.
Researchers developed a PCOS-specific questionnaire to measure disease-related dysfunction in women with polycystic ovary syndrome (PCOS). The Polycystic Ovary Syndrome Questionnaire (PCOSQ) improves quality of life perception with therapy, particularly for hirsutism and excess weight.
Researchers engineered mice to lose glucocorticoid receptors, showing an increase in depression-like behaviors and impaired regulation of stress response. This study suggests that genetic makeup may play a role in triggering depression by affecting the brain's ability to regulate adrenal hormones.
A large study of 188 women found that nearly 55% with minimal unwanted hair growth had an androgen excess disorder, primarily polycystic ovary syndrome (PCOS). Women with PCOS often struggle with menstrual irregularities, skin problems, and excess weight.
A national study published in the New England Journal of Medicine found that vaginal birth after a cesarean section (VBAC) is more dangerous for mothers, with higher rates of uterine rupture and endometritis. However, the risk remains small, and researchers recommend thorough counseling for women considering VBAC.
Women who averaged less than six hours of sleep per night had significantly longer labors and were more likely to have cesarean deliveries. The study also found that women who reported having poor sleep quality were more likely to experience these outcomes.
A multicenter study found women attempting vaginal birth after C-section (VBAC) face increased risk of maternal morbidity and serious obstetric complications. Conversely, elective repeat cesarean delivery shows lower risks for these complications.
Yale researcher Nita Maihle has been awarded a visiting professorship at Pfizer, where she will collaborate on cancer research for 12 weeks. The program aims to improve the drug discovery process and facilitate associations among Yale investigators and Pfizer staff.
Scientists have successfully cloned primates up to the blastocyst stage, a developmental milestone for embryonic stem cell research and potential treatments for diseases such as diabetes and Parkinson's. The breakthrough could pave the way for deriving human embryonic stem cells from nonhuman primate templates.
A new study by Dr. Katherine Hartmann found that women experience significant improvements in self-reported pelvic pain and depression two years after hysterectomy. The study involved nearly 1,300 women who reported a reduction in symptoms, with the group experiencing both conditions showing the most improvement.
The seven-year contract will target non-HIV STIs and include microbicides, vaccines, STI treatments and diagnostic products. Students from international partners can participate in a yearlong program at UCSF for certification and mentoring.
A study found that women treated with clindamycin for bacterial vaginosis experienced more frequent increases in E. coli concentrations and higher rates of clindamycin-resistant bacteria compared to those treated with metronidazole. In contrast, metronidazole therapy resulted in increased colonization by protective Lactobacillus species.
A study published in American Journal of Obstetrics and Gynecology found that infections occur around birth are associated with an increased risk of periventricular leukomalacia (PVL), a condition causing brain tissue death. PVL is the most common form of brain injury in premature infants, resulting in cerebral palsy.
Leading researchers, including Gerald Schatten, explore the potential of stem cells from therapeutic cloning for treating various diseases. However, concerns over safety, efficacy, and ethical implications remain a topic of debate.
Researchers at the University of Michigan are collaborating on a three-year project to address racial disparities in pregnancy outcomes. The study aims to develop more comprehensive and coordinated prenatal care strategies, as well as evaluate the role of leadership, providers, and patients in improving health equity.
A recent study published in the American Journal of Obstetrics and Gynecology found that episiotomies do not reduce the likelihood of shoulder injuries to infants stuck in the birth canal. Instead, rotating the infant may realign its shoulders to fit within the mother's pelvis.
A large study found that at least one in four pregnant women experience restless legs syndrome, with symptoms worsening during rest and improving with activity. The study suggests a correlation between low iron indicators and the risk of developing RLS, highlighting the need for further research into its causes.
The article reports a record number of active medical residents (99,964) in the 2003-2004 academic year, with a notable increase in female graduates. Several specialties experienced a decline in male graduates, while others saw an increase in female graduates, reflecting a trend towards a more specialized and diverse medical workforce.
A double-blind, randomized trial found that first-line treatment with DETROL(R) LA significantly reduced urge incontinence episodes and improved bladder condition in women with mixed incontinence. The study also showed a higher proportion of patients treated with DETROL(R) LA reported treatment benefits.
A study by University of Toronto researchers found that only 38.5% of Urdu- and Hindi-speaking women had undergone a clinical breast examination, despite 83% being aware of the procedure. The study highlights gaps in knowledge about breast cancer risk and screening methods among South Asian immigrant women.
Researchers found that ovarian cancer tumors lack response to antiestrogens due to decreased ER beta expression, which can lead to increased cell proliferation and apoptosis. The reintroduction of ER beta in cancer cells induced apoptosis, suggesting its regulatory functions in controlling ovarian cancer growth and motility.
A jumping gene called mUtp14b has been found to affect fertility in mice, with a mutation leading to sterility. Researchers believe this gene may play a role in male infertility in humans and are investigating its potential impact.
A multi-center study found that consistent condom use halves the risk of recurrent PID, reducing chronic pelvic pain and infertility. Women using condoms were also 60% less likely to become infertile.
Researchers at OHSU have discovered a possible method for early detection and prevention of premature birth by identifying biomarkers associated with intra-amniotic infections in both animal and human studies. The breakthrough technology has the potential to save young lives and may lead to significant health benefits.
Gary Whitman, MD, and Alfred Abuhamad, MD, were selected for the award due to their extensive participation in AIUM activities, teaching, and committee memberships. The American Institute of Ultrasound in Medicine has promoted safe and effective ultrasound use in clinical medicine for over 50 years.
Women with vulvodynia process pain differently, exhibiting lower pain tolerance at multiple sites throughout the body. The study suggests a neurological basis for the condition, recommending treatment aimed at central pain processing.
Researchers discovered that replenishing depleted neurosteroid hormone allopregnanolone significantly delayed neurological deficits and doubled the lifespan of mice with neurodegenerative disease. The treatment was particularly potent when administered early in life and showed promise for delaying symptom onset and progression.
A new study by UNC researchers reveals that primary-care doctors who received comprehensive smoking cessation intervention training during residency are more likely to continue using these methods in their medical practice years later. The long-term effects of such training on physician behavior have significant implications for public...
Researchers discovered that donor-derived bone marrow cells can differentiate into human endometrial tissue, contributing to endometrial regeneration. This finding may lead to new treatments for uterine disorders like infertility, abnormal bleeding, and cancer.
The Meharry-Penn State U54 Cooperative Reproductive Science Center aims to address health disparities in women's reproductive endocrinology. Four research studies currently recruiting participants will investigate racial differences in reproductive conditions such as polycystic ovary syndrome and fibroids.
A new technique for preserving fertility in young women with cancer has been successfully used on eight female patients. The method involves removing immature eggs from the ovaries, maturing them through in-vitro maturation (IVM), and freezing them for later use.