A recent study published in the American Journal of Psychiatry found that guanfacine, a commonly prescribed medication for post-traumatic stress disorder (PTSD), is no more effective than a placebo. The study, led by researchers at the San Francisco VA Medical Center, involved 63 male and female veterans who received either weekly dose...
A neuroimaging study at the University of Pennsylvania School of Medicine found decreased activity in frontal lobes and increased thalamus activity when subjects spoke in tongues. The study suggests that glossolalia may be associated with non-intentional control by another part of the brain, challenging traditional views on language co...
A standardized way to evaluate the risk posed by someone who collects kiddie porn on the Internet is still in development. Forensic psychiatrists face challenges in assessing the possession of internet child pornography without offending or predicting future abuse.
The FBI's profiling method for serial killers is criticized for its limitations, particularly in cases involving women and non-Caucasian offenders. Experts argue that crime scenes often exhibit both organized and disorganized components, making it challenging to develop accurate profiles.
A new study from UC Davis found that older men face barriers to seeking and receiving depression care due to societal stereotypes and stigma. Traditional views of masculinity lead some men to reject diagnoses and conceal symptoms, resulting in lower rates of treatment and referral.
A recent study published in The British Journal of Psychiatry found that genetic inheritance is the main cause of unexplained disabling fatigue in children. The research, conducted at Cardiff University, suggests that familial influences play a significant role in both short- and prolonged-duration fatigue.
Finnish soldiers rarely sought compensation for psychological war injuries due to a culture of shame. Researcher Ville Kivimäki's study reveals that restrictive war psychiatry created a reality where traumatic experiences were stigmatized, limiting veterans' ability to express their traumas.
A study published in the American Journal of Geriatric Psychiatry identified nine genetic regions associated with successful aging, with some affecting men and women differently. Lifestyle factors such as smoking and excessive drinking also played a significant role in successful aging.
Researchers at Washington University School of Medicine found that nearly half of children with attention-deficit/hyperactivity disorder (ADHD) are not receiving treatment. The study, which analyzed data from over 1,600 twins, suggests that many cases of ADHD may be underdiagnosed or undertreated.
A study of 93 patients found that more than half with clozapine treatment had metabolic syndrome, a group of conditions increasing heart disease and diabetes risk. Regular monitoring is crucial for patients taking clozapine due to its potential long-term health implications.
A study found that nearly half of elementary school teachers admitted to bullying students, with a strong correlation between those who were bullied in childhood and those who bully others as adults. This highlights the need for teacher support and effective discipline methods to prevent bullying.
Researchers discover altered activity in NRG1-erbB4 and NMDA receptor pairs, suggesting a relationship between the two and contributing to schizophrenia symptoms. The study's findings provide new insights into the molecular mechanisms underlying the disease.
The STEPPS program, developed by Nancee Blum and colleagues, enhances standard treatment for borderline personality disorder with group meetings focusing on self-awareness and behavioral skills. Researchers in the Netherlands report a significant reduction in hospitalization days and improved symptoms among participants.
Researchers at Yale discovered that brain changes associated with bipolar disorder are diminished in patients taking mood-stabilizing medications, holding promise for halting the progression of the disorder. The study's findings highlight the importance of research on bipolar disorder in youths, who are at high risk for suicide.
Researchers in antidepressant studies focus on symptoms to gauge remission, while patients prioritize factors like positive mental health and return to usual functioning. Studies suggest that patients consider multiple factors beyond symptom disappearance to determine remission from depression.
A third of patients with major depressive disorder (MDD) fully recovered from symptoms after initial treatment with antidepressant medication. Nearly 47% showed a response rate, with one in three achieving symptom-free state.
A new case of dementia arises every seven seconds worldwide, with 60% of those affected living in developing countries. By 2040, rates are projected to rise by 71% in developing countries and 100% in developed countries.
Researchers discovered sequence variations in the DISC1 gene that predict schizophrenia, neurocognitive deficits, and brain structure abnormalities. The study's findings offer hope for developing a treatment that can prevent or fix the protein's function.
A recent study contradicts earlier research suggesting that the neural development protein Oct-6 could be a marker for schizophrenia and bipolar disorder. Contrary to previous results, researchers found no difference in Oct-6 protein or mRNA expression between patients with these disorders and healthy individuals.
Researchers found that children with bipolar disorder exhibit over-reactive amygdala responses to negative stimuli, leading to under-reactive cognitive behavior. This study highlights the need for targeted treatments and interventions for pediatric bipolar disorder.
A multi-site study found Risperidone effective in decreasing aggression, repetitive behaviors, and increasing social interaction in children with autism. The medication showed limited side effects, supporting its use as an intermediate-term treatment option.
A study of 72 adolescent marijuana users found that nearly two-thirds experienced four or more symptoms of marijuana withdrawal, including anxiety and irritability. The majority of participants also reported experiencing some withdrawal symptoms after abruptly stopping daily or near-daily use.
A trial found that raloxifene, a commonly prescribed drug for osteoporosis, reduced the risk of mild cognitive impairment by 33% in postmenopausal women. The study suggests that estrogen-like effects on the central nervous system may play a role in this finding.
A meta-analysis of 20 studies found light therapy to be an effective treatment for SAD and depression, with effects comparable to conventional medications. The study suggests that bright artificial light can help alleviate symptoms of SAD and other non-seasonal mood disorders.
A comprehensive treatment approach for all schizophrenia symptoms is possible, enabling patients to recover and lead fuller lives. Atypical antipsychotics have shown promise in improving cognition and addressing depressive symptoms, but individual side effects and preferences must be considered.
The new guidelines, developed by a team of leading experts in child psychiatry, provide evidence-based recommendations for treating children and adolescents with bipolar disorder. The guidelines emphasize the importance of using multiple medications to stabilize moods and promote recovery.
Adolescent smokers showed impairments in accuracy of working memory performance, with males more affected. Those trying to quit smoking also experienced further disruption of working memory.
Researchers found a genetic variation in the CRH gene associated with a 70% greater reduction in anxiety and 30% greater reduction in depression in response to certain antidepressants. This discovery shows promise in helping physicians tailor prescriptions to specific people, offering a more targeted approach to treating depression.
Researchers found a three-fold increase in suicide rates in two Salisbury, N.C., neighborhoods downwind of an asphalt terminal. Hydrogen sulfide levels were significantly higher than the World Health Organization's recommended standard, and exposure to other neurotoxic compounds may also be contributing factors.
A study published in the British Journal of Psychiatry found that electroconvulsive therapy (ECT) improves mood, quality of life, and activities of daily living in patients with major depression. Sixty-six percent of patients showed significant improvement after ECT treatment.
The study found that individuals with a family history of alcoholism were less sensitive to ketamine and exhibited altered NMDA receptor function. This suggests a genetic predisposition to vulnerability to heavy drinking in the presence of environmental and social factors.
A study by UT Southwestern Medical Center found that teens with depression experience significant improvement when treated with a combination of medication and cognitive-behavior therapy. The treatment resulted in a 71% improvement rate, compared to 60% for those taking Prozac alone or 43% for those receiving only therapy.
Researchers Wade Berrettini and Irwin Lucki received Distinguished Investigator Awards to study gene identification and behavioral effects of neurotrophins. Monica Gonzalez won a Young Investigator Award to investigate the effect of long-term light deprivation on depression.
Patients with major depressive disorder showed significant improvement in symptoms and medical outcomes when treated according to the Texas Medication Algorithm Project (TMAP) guidelines. The study, published in Archives of General Psychiatry, found a two-to-three times greater improvement rate compared to standard treatment.
Researchers have found that genetic variations in the GABRA6 gene contribute to individual differences in stress response. The study suggests a link between this gene polymorphism and an attenuated stress response.
A recent study published in the American Journal of Psychiatry found that moderately depressed seniors require significantly more hours of care than those without symptoms. If caregivers were paid for their work, the annual cost would be approximately $9 billion, highlighting the impact of depression on seniors and their loved ones.
A study published in the American Journal of Psychiatry found that enhanced counseling, including individual and family therapy, reduced symptoms of depression among caregivers of loved ones with Alzheimer's disease. After one year, 29.8% of caregivers in the enhanced group showed significant improvement.
Researchers found that Tourette syndrome patients' brain activity during memory tasks normalized after receiving levodopa treatment. The study used functional magnetic resonance imaging and showed increased activity in certain brain regions, which decreased after treatment.
A new study published in Archives of General Psychiatry found that earlier diagnosis and treatment of schizophrenia significantly improves patient outcomes. Patients treated early tended to be younger, less symptomatic, and more responsive to treatment than those not receiving early detection programs.
A study found that NS temperament in adulthood was predicted by an interaction between the DRD4 gene polymorphism and a hostile childhood rearing environment. Participants with certain genetic variants and adverse childhood experiences had a higher risk of exhibiting high novelty seeking scores.
The Emory-GSK-NIMH Collaborative Mood Disorders Initiative will develop innovative models for basic and clinical research in mood disorders. Scientists at NIMH will create clinical models to assess novel antidepressants, while Emory faculty will develop preclinical models of fear, anxiety, and depression.
A recent study published in Molecular Psychiatry reveals that cell death promotes learning and growth in the brain. The research found that rats with lower levels of cell death performed better in spatial learning tasks, suggesting a positive correlation between cell death and cognitive function.
A new genetic variant has been identified in individuals with obsessive-compulsive disorder (OCD), showing a strong link to the development of the condition in multiple generations. The I425V mutation affects serotonin transporter function and is rare, found in only 7 out of 833 individuals studied.
A study published in Molecular Psychiatry found that a specific gene variant, M129V, affecting the prion protein is associated with changes in cognitive performance. Researchers discovered this link while investigating genetic influences on mental health disorders, also noting a connection to mad cow disease.
A study by Ohio State University researchers found that even mild depression in caregivers can lead to increased inflammation, which is associated with various age-related illnesses. Chronic inflammation has been linked to declines in physical function and an increased risk of mortality.
A new study conducted in the UK shows that forgiveness is a complex process in the brain, involving multiple cognitive components. The research found that different parts of the brain are activated when making moral judgments, empathizing with someone, and ultimately judging forgivability.
Researchers found that variations in genes related to serotonin receptors and liver enzyme CYP2D6 impact antidepressant efficacy and side effects. The study suggests personalized treatment approaches based on individual genetic profiles.
The study found that nearly 68% of patients who received antidepressant treatment were alive after nine years, compared to about 36% of those who received placebo. The researchers believe antidepressants may provide protective effects by improving recovery and reducing mortality in stroke patients.
A Yale University study found that supported housing programs for homeless veterans were more effective than standard care in reducing homelessness. The study showed a 25% increase in nights housed and larger social support networks among participants receiving combined housing vouchers and intensive case management.
A study led by NYU Langone Health found that epilepsy drug GVG helped hard-core cocaine addicts stay clean for over 60 days. Forty percent of participants achieved sobriety without leaving their environment, gaining weight and living with their families.
A new four-year study aims to explore the effectiveness of advance directives in mental health care, with over 500 patients enrolled. The study seeks to determine whether providing resources and support can encourage patients with serious psychiatric disorders to create legally valid advance instructions for mental health treatment.
Paxil has been shown to improve memory and brain structure in PTSD sufferers, with clinically significant improvements in memory and concentration observed. The study found increased hippocampal volume and decreased cortisol levels, leading to relief of PTSD symptoms.
A study published in the Journal of Clinical Psychiatry found that divalproex improved mood and behavioral disorders in over 78% of at-risk children. The medication may delay or prevent the onset of bipolar disorder, offering an alternative treatment option.
Researchers found that antidepressant treatment appears to preserve hippocampal volumes in depressed patients, compared to those who have not taken medication. The study suggests that using antidepressants whenever symptoms occur may help prevent long-term brain damage.
Researchers identify key genes and cellular pathways contributing to schizophrenia, providing new insights into the disorder's complex biology. The study's findings hold promise for developing novel therapeutic strategies.
A study led by Constantine Lyketsos found that sertraline hydrochloride significantly improved the quality of life and reduced functional decline in Alzheimer's patients with depression. The treatment showed a positive influence on 84% of participants, while only 35% in the placebo group experienced improvements.
A study published in the Journal of Clinical Psychiatry found that patients taking citalopram scored lower on a scale measuring compulsive shopping tendencies compared to those on a placebo. The majority of participants reported significant improvement in their symptoms, including reduced urges and interest in shopping.
A study found that doctors and mental-health professionals often fail to address alcohol consumption during visits, even when patients have multiple health or social problems. This missed opportunity can lead to inadequate treatment referrals and counseling.
A study published in Molecular Psychiatry has identified a sex-specific gene variant associated with an increased risk of developing severe depression in women. Over 80% of women who inherited the CREB1 variant developed depressive disorders, highlighting the importance of considering sex-specific factors in depression research.
Hypochondriasis affects 4-9% of primary care outpatients, leading to insecure attachment and problems with health care satisfaction. The study suggests that childhood adversity and insecure attachment can contribute to hypochondriasis in adulthood, highlighting the need for effective treatments like cognitive behavioral therapy.