Search results for “breast cancer”

Genetic testing, computer risk-assessment software prove effective in predicting breast cancer

A study published in the Journal of the National Cancer Institute found that genetic testing using breast cells can accurately predict breast cancer risk. The Gail model, a computer-based predictor, was correlated with DNA deletions and precancerous changes in cells, suggesting an individualized approach to risk assessment.

SourceUT Southwestern Medical Center·JournalJNCI Journal of the National Cancer Institute·DateJun 5, 2002

An early warning system for dangerous breast cancer?

A test to detect the RhoC protein has shown promising early results, detecting invasive cancers with high specificity and identifying tiny tumors that have already metastasized. The study aims to identify early-stage cancer that could be vulnerable to aggressive treatment, potentially leading to improved patient outcomes.

SourceMichigan Medicine - University of Michigan·DateApr 9, 2002

Excessive weight gain during pregnancy can increase breast cancer risk, study finds

A study of over 27,000 breast cancer patients in Finland found that excessive weight gain during pregnancy increases breast cancer risk after menopause. Researchers discovered that each 1 kg increase in pregnancy weight boosts the risk by 3.9%, with women who retain excess pounds post-pregnancy facing the greatest threat.

SourceGeorgetown University Medical Center·DateApr 9, 2002

From sci-fi to reality – microendoscopy to diagnose breast cancer?

The microendoscopy technique uses a tiny endoscope to detect abnormal cell changes in breast ducts, potentially identifying breast cancer up to a decade before it develops. Researchers have had successes with the procedure and plan to use it as a diagnostic tool for high-risk patients.

SourceECCO-the European CanCer Organisation·DateMar 22, 2002

First IBIS results show tamoxifen reduces breast cancer in healthy high-risk women

The International Breast Cancer Intervention Study (IBIS) found that tamoxifen reduced breast cancer incidence by 38% in healthy high-risk women. However, the benefits of tamoxifen for prevention in these women are unclear due to potential side effects and risks.

SourceECCO-the European CanCer Organisation·DateMar 20, 2002

Early breast and ovarian cancers detected in high-risk women

A study at Memorial Sloan Kettering Cancer Center found that BRCA mutation carriers are more likely to be diagnosed with early-stage breast and ovarian cancers. The research showed that intensive screening and preventive surgery can lead to the detection of these cancers, but also highlights the limitations of screening.

SourceMemorial Sloan Kettering Cancer Center·JournalJournal of Clinical Oncology·DateMar 1, 2002

Early breast cancer shares some risk factors with advanced breast cancer, a study by Yale researchers shows

A new study by Yale researchers found that many risk factors for early breast cancer are also linked to advanced breast cancer. The study, which included over 1,000 women diagnosed with early breast cancer, revealed a correlation between family history, previous breast biopsy, and older age at menopause.

SourceYale University·JournalJNCI Journal of the National Cancer Institute·DateJan 16, 2002

Non-invasive technique for detecting women at increased risk for breast cancer proven useful in UCSF study

A new non-invasive technique using modified breast pumps to collect breast fluid samples shows promise in predicting breast cancer risk. Women with normal cells in their fluid are 30% more likely to develop cancer, while those with abnormal cells are twice as likely.

SourceUniversity of California - San Francisco·JournalJNCI Journal of the National Cancer Institute·DateDec 4, 2001

Anxiety over breast self-examination may lead to low compliance, UCLA researchers find

UCLA researchers found that anxiety about breast self-examination leads to low compliance among high-risk women. Only 34% of participants performed regular breast self-exams, despite high rates of mammogram and Pap smear adherence.

SourceUniversity of California - Los Angeles·JournalAnnals of Behavioral Medicine·DateNov 9, 2001

Breast cancer in relatives of women with breast cancer

Researchers found that the number of affected relatives is a stronger predictor of breast cancer risk than the age at diagnosis. Women with one or two affected relatives have significantly higher lifetime incidence rates (7.8% and 13.3%, respectively), while those with three affected relatives face the highest risk (21.1%).

SourceThe Lancet_DELETED·JournalThe Lancet·DateOct 25, 2001

Avon Products Foundation awards Fred Hutchinson Cancer Research Center $2.5 million for breast cancer research and clinical care

The Fred Hutchinson Cancer Research Center has received a $2.5 million gift from the Avon Products Foundation to support innovative breast cancer research and clinical care initiatives, including immune response-based treatments and access to quality care for medically underserved women.

SourceFred Hutchinson Cancer Center·DateAug 13, 2001

August news briefs

A Mayo Clinic study published in Cancer journal reveals that daily alcohol consumption by women whose mothers, sisters or daughters have breast cancer may increase their risk for getting the cancer. The study found an increased risk among first-degree relatives of women with breast cancer, but less evidence among second-degree relatives.

SourceMayo Clinic·JournalCancer·DateAug 10, 2001

Early oral contraceptive formulations linked to breast cancer risk

Women with a strong family history of breast cancer who have used early oral contraceptives, particularly those introduced before 1975, may be at heightened risk of developing breast cancer. The study found a 3.3-fold increased risk for first-degree relatives, especially sisters and daughters.

SourceMayo Clinic·JournalJAMA·DateOct 9, 2000

Radiation safe and effective for treating breast cancer patients with BRCA1 or BRCA2 mutations

Researchers found radiation therapy to be both safe and effective in preventing cancer recurrence in women with BRCA1 or BRCA2 mutations. However, women with these genetic mutations were more likely to develop cancer in their unaffected breast.

SourceAmerican Society of Clinical Oncology·JournalJournal of Clinical Oncology·DateSep 28, 2000

Study challenges mammogram effectiveness in breast screening

A study found that breast cancer mortality was almost identical in two groups of women aged 50-59, one receiving annual mammograms and the other physical examinations alone. Effective and regular breast physical examinations with breast self-examination may be an alternative to annual mammograms for this age group.

SourceUniversity of Toronto·JournalJNCI Journal of the National Cancer Institute·DateSep 18, 2000

Leading breast cancer researchers will present latest findings

Renowned scientists and clinicians will discuss recent advances in breast cancer science and treatment, including new developments in imaging techniques, hormone replacement therapy, and alternative therapies. The symposium will feature prominent speakers from top medical institutions.

SourceNorthwestern University·DateSep 10, 2000

2nd European Breast Cancer Conference unites scientists and patients

The 2nd European Breast Cancer Conference will bring together over 3000 healthcare professionals, scientists, and patient advocates to share new developments in breast cancer research, treatment, and care. Distinguished international speakers will address key issues about the future of breast cancer research, treatment, and care.

SourceECCO-the European CanCer Organisation·DateAug 3, 2000

UNC opens first clinical trial of vaccine treatment for advanced breast cancer

Researchers at UNC Lineberger Comprehensive Cancer Center are conducting a clinical trial using a genetically engineered protein fragment to stimulate the immune system to recognize and kill breast cancer cells. The goal is to treat advanced breast cancer, where the disease has spread beyond the breast.

SourceUniversity of North Carolina Health Care·DateJun 29, 2000

Breast is still best, though breast-fed infants may show initial slower weight gain

Exclusive breast-feeding for four months may lead to a short-term lag in weight gain, but does not affect long-term growth patterns. Infants who were breast-fed exclusively for at least four months had improved growth status compared to those who were never breast-fed.

SourceAmerican Journal of Clinical Nutrition·JournalAmerican Journal of Clinical Nutrition·DateJun 25, 2000

Combined hormone-replacement therapy may boost incidence of rare form of breast cancer

Researchers found a significant increase in lobular breast cancer among postmenopausal women taking combined hormone-replacement therapy. The study reported a 2.6-fold increase in incidence among those who took the therapy for six months or more.

SourceFred Hutchinson Cancer Center·JournalCancer·DateMay 31, 2000

No link found between PCBs and DDE and breast cancer risk in women

A large case-control study of nearly 1,000 Connecticut women found no significant association between PCBs or DDE exposure and breast cancer risk. The research suggests that previous studies on the topic have been inconclusive due to small sample sizes and lack of consideration for modifying factors.

SourceYale University·DateFeb 17, 2000

Scientists report marker of increased cancer risk in women with benign breast disease

Researchers found a link between reduced TGFb receptor expression and increased breast cancer risk in women with benign breast disease. The study identified 54 women who developed invasive breast cancer after initial hyperplasia diagnosis, highlighting the importance of molecular markers in predicting breast cancer risk.

SourceVanderbilt University Medical Center·JournalJNCI Journal of the National Cancer Institute·DateDec 14, 1999

Breast-feeding plays second fiddle to work, study finds

A recent study published in Demography found that breast-feeding duration is significantly impacted by workplace demands. Women who work full-time have the lowest breast-feeding rates, while those working part-time or with flexible schedules tend to breast-feed more frequently.

SourceOhio State University·JournalDemography·DateOct 26, 1999

Jefferson study shows women with inherited breast cancer gene at greater risk for recurrence and new tumors

Researchers found that women with BRCA1 or BRCA2 mutations have a 40% risk of local recurrence and developing new tumors, making breast-conserving therapy less optimal. The study suggests that mastectomy may be a more suitable treatment option for these women to reduce the risk of recurrent disease.

SourceThomas Jefferson University·JournalJournal of Clinical Oncology·DateSep 29, 1999

New test can better uncover hidden breast cancer

A new test developed by USC scientists and colleagues can accurately detect hidden breast cancer cells in lymph nodes, improving the detection of metastases. This breakthrough enables customized treatments tailored to individual patients' characteristics, such as tumor size and hormone receptor status.

SourceUniversity of Southern California·JournalThe Lancet·DateSep 10, 1999

Penn researchers find ovary removal reduces risk of breast cancer in women withBRCA1 mutation

Researchers at the University of Pennsylvania Cancer Center found that bilateral prophylactic oophorectomy reduces breast cancer risk in women with a BRCA1 gene mutation. After 10 years, the incidence of breast cancer among women who had their ovaries removed was significantly lower than those who did not.

SourceUniversity of Pennsylvania School of Medicine·JournalJNCI Journal of the National Cancer Institute·DateSep 1, 1999

UCSF study finds that an osteoporosis prevention drug reduces the risk of breast cancer by 76 percent in postmenopausal women

A UCSF study found that raloxifene, an osteoporosis prevention drug, significantly reduced the risk of invasive breast cancer in postmenopausal women by 76 percent. The drug also showed promise in preventing both breast and osteoporosis simultaneously.

SourceUniversity of California - San Francisco·JournalJAMA·DateJun 16, 1999

Study Shows Hormone Replacement Therapy Does Not Elevate Breast Cancer Risk

A new study published by Vanderbilt University Medical Center researchers found that estrogen replacement therapy (ERT) does not significantly elevate the risk of breast cancer in women with histories of benign breast disease. Women already face a higher risk, but ERT does provide benefits for heart and bone health.

SourceVanderbilt University Medical Center·JournalCancer·DateMar 15, 1999

Microscopic Change May Double Breast Cancer Risk For Some Women

A large study has identified a microscopic change in breast tissue that may double the risk of breast cancer in some women. Radial scars were found in nearly 100 out of 1,400 women with benign breast biopsies, doubling their risk of breast cancer independently of other tissue abnormalities.

SourceHarvard Medical School·JournalNew England Journal of Medicine·DateFeb 11, 1999

Osteoporosis Drug Evista® (Raloxifene) Cuts Newly Diagnosed, Invasive Breast Cancer Risk By More Than 60 Percent

A new study from Northwestern University found that Evista (raloxifene) significantly reduces the risk of invasive breast cancer in postmenopausal women, with a 63% decrease in newly diagnosed cases. The medication has also been shown to lower cholesterol and protect against bone loss and osteoporosis-related fractures.

SourceNorthwestern University·DateDec 11, 1998

Research Grant To Wistar Institute Involves Linda Creed Breast Cancer Foundation In Breast Cancer Research

The Wistar Institute has been awarded a $20,000 grant to support continued research on TALL-104 cells, which show promise in treating breast cancer. The grant allows the Linda Creed Breast Cancer Foundation to be involved in supporting clinical trials for new treatments and perhaps a cure.

SourceThe Wistar Institute·DateDec 7, 1998

New Genetic Mutation Linked To Breast Cancer Risk Poses Less Risk Than Previously Discovered Gene Mutations

A new genetic mutation, APC I1307K, is found to modestly increase the risk of hereditary breast cancer in women of Ashkenazi Jewish descent. The mutation's effect is most significant in those who already carry BRCA mutations.

SourceMemorial Sloan Kettering Cancer Center·JournalNature Genetics·DateAug 31, 1998

New Study Of BRCA1 Shows No Need For Widespread Screening Of American Women

A recent study published in JAMA found that only 3.3% of white women and 0% of black women with breast cancer had disease-related BRCA1 mutations. The researchers conclude that widespread screening is not necessary for the general American population, but may be beneficial for high-risk families.

SourceUniversity of Washington·JournalJAMA·DateMar 24, 1998

20 Months Total Breast-Feeding May Lower A Woman's Risk Of Developing Breast Cancer

A recent study found that premenopausal women who breastfed for at least 20 months had a 50% lower risk of breast cancer compared to those who did not breastfeed. The study also revealed no effect on the risk of breast cancer for postmenopausal women.

SourceUniversity at Buffalo·JournalAmerican Journal of Epidemiology·DateDec 2, 1997

Study Detects Benefits From Effective Breast Self Examination

A recent study found that women who perform specific components of Breast Self Examination (BSE) may have a reduced risk of dying from breast cancer. The three key components associated with this benefit are visually examining the breast, using finger pads to examine the breast, and using three middle fingers to examine the breast.

SourceUniversity of Toronto·JournalCanadian Medical Association Journal·DateOct 31, 1997

Deaths From Breast Cancer Decreasing

The number of women dying from breast cancer is decreasing due to earlier detection through mammography. Physicians play a key role in recommending and performing mammograms, with 93-94% of women complying with requests.

SourceUniversity of Toronto·DateOct 7, 1997

Scientists Identify A Tumor Suppressor Gene Implicated In Breast Cancer

Researchers discovered that abnormal expression of the WT1 gene is linked to nearly 70% of breast cancers, which may lead to new treatments. The study suggests restoring functional tumor suppressor genes like WT1 could help combat breast cancer.

SourceOregon Health & Science University·JournalProceedings of the National Academy of Sciences·DateJul 21, 1997

High Bone Mass Associated With Breast Cancer Risk In Postmenopausal Women

A long-term epidemiological study found that postmenopausal women with the highest bone mass have a 3.5 times increased risk of developing breast cancer compared to those in the lowest quartile of bone mass. The study suggests that high bone mass may be associated with increased exposure to estrogen, which is linked to breast cancer de...

SourceNIH/National Heart, Lung and Blood Institute·DateFeb 27, 1997

Study Finds Breast-Feeding May Lower Women's Risk Of Breast Cancer

A new study by epidemiologists at the University at Buffalo found that premenopausal women had a 29% lower risk and postmenopausal women a 24% lower risk of breast cancer if they had breast-fed for at least 12 months. The positive effect was found only for those who first breast-fed before age 25.

SourceUniversity at Buffalo·DateJun 13, 1996

Second Breast Cancer Gene Located

Researchers at Duke University and the Institute for Cancer Research have located a second breast cancer susceptibility gene, BRCA2. This gene is expected to account for most of the remaining 50% of inherited breast cancers not caused by BRCA1. Women who inherit BRCA2 are at an 85% risk of developing breast cancer.

SourceDuke University·DateApr 29, 1996