A recent study published in Reproductive BioMedicine Online examines the outcomes of assisted reproduction treatment for same-sex male couples and single men. The research found that high success rates can be achieved, particularly among persistent individuals, with most men successful in realizing their dream of fatherhood.
A new online risk calculator estimates an individual's likelihood of treatment resistance to antidepressants, providing a graphical estimate based on statistical patterns from the STAR*D study. The calculator aims to help clinicians design personalized treatment plans for patients with depression.
GeoResJ aims to publish top research in the entire earth science field with rapid publication and open access. Elsevier's new journal joins its existing earth and planetary science journals offering authors more choice for scope and access.
The National Osteoporosis Guideline Group (NOGG) Update 2013 provides updated guidance on the diagnosis and management of osteoporosis. The new recommendations cover glucocorticoid-induced osteoporosis, calcium and vitamin D therapy, and long-term bisphosphonate therapy.
International Economics is a peer-reviewed journal that publishes original research papers on various topics in international economics. The journal is dedicated to advancing our understanding of global economic relationships and the world economy.
A new study found that patients with PTSD who have a less functional variant of the BDNF gene respond poorly to exposure therapy. The study suggests that BDNF levels modulate the therapeutic effects of treatments for mood and anxiety disorders.
A new study suggests that long-term antidepressant treatment impairs fear extinction learning in rats, which may disrupt the effectiveness of exposure therapy. The authors propose a mechanism involving decreased NMDA receptor subunits in the amygdala.
The latest themed issue of Reproductive Health Matters explores the unmet needs of adolescents regarding reproductive health, sex education, and relationships. Papers from around the world address key issues such as HIV misinformation, menstrual health, and safe abortion services.
The new journal aims to cover all areas of research in human proteomics, using multi-disciplinary approaches to untangle complex disease processes. It will provide a platform for high-quality, multi-disciplinary studies combining early discovery with clinical applications.
A new study published in Biological Psychiatry found a link between genetic risk for schizophrenia and lower IQ, suggesting common genetic variants may contribute to cognitive decline. The research analyzed data from 937 individuals and found that those with higher genetic risk had lower IQ at age 70 but not at age 11.
Researchers have developed a method to identify embryos with chromosomal abnormalities using time-lapse imaging and morphokinetic analysis, avoiding invasive biopsies. This approach has shown significant improvements in implantation and live birth rates when low-risk embryos are transferred.
The EMAS clinical guide provides recommendations for assessing the endometrium in peri and postmenopausal women to exclude carcinoma of the endometrium and premalignant hyperplasia. Transvaginal ultrasound scanning is used for initial assessment, followed by endometrial biopsy as an outpatient procedure.
A new engineered protein from a reaper spider's venom may offer a promising candidate for therapeutic serums or vaccination against other venoms. The protein provides effective protection against the effects of pure spider venom in animal models.
A new study published in the Journal of the American Academy of Child and Adolescent Psychiatry found that schools significantly associated with adolescent mental health service use. Schools that engage in early identification of emotional problems were more likely to receive mental health services.
Researchers have developed a new, more precise form of electroconvulsive therapy (ECT) called FEAST, which shows promising results in reducing depressive symptoms with minimal adverse cognitive effects. In a feasibility study, patients experienced significant improvements after just 10 sessions over four weeks.
Research examines similarities between food intake and addiction, but debates the application of the addiction model to food. A special issue in Biological Psychiatry explores the state of the field, covering neurobiological mechanisms, brain reward circuitry, and risk factors.
Classic psychological research on expectancy and observer effects reveals flaws in forensic science, including the influence of human examiners and flawed evidence. The study proposes best practice recommendations to reduce confirmation biases and improve the quality of the judicial system.
A previously unpublished work by Francis Crick and Jeffries Wyman from 1965 is now available, proposing a different formulation of the Monod-Wyman-Changeux hypothesis. The paper analyzes how regulatory performances of monomeric proteins are enhanced by assembly into cooperative structures.
A new study published in Biological Psychiatry reports that high frequency transcranial magnetic stimulation (TMS) over the prefrontal cortex temporarily reduced cue-induced smoking craving in nicotine-dependent individuals. The treatment, which targets brain function and behavior, showed promise as a potential tool for smoking cessation.
Researchers discovered that nalmefene significantly reduces alcohol consumption and improves patients' clinical status and liver enzymes. The medication is well-tolerated with mild to moderate side effects.
A new study published in Reproductive Biomedicine Online reveals that blastocysts' fluid-filled cavities contain DNA from the embryo, allowing for diagnosis of genetic diseases without biopsy. Researchers extracted fluid from embryos at the 5-day-old stage and detected cell-free DNA using PCR and DNA microarray analysis.
A new study published in Biological Psychiatry found that common genetic variants explain 42% of individual differences in antidepressant response, providing a significant step towards personalized treatment for depression. The research identified multiple genetic markers involved in predicting response to antidepressants.
A new study published in Biological Psychiatry found that humans report emotions in three distinct systems: attention, categorization, and intensity. The researchers used brain scans to examine the neural architecture underlying emotional reports.
A special issue of Translational Research highlights the progress and challenges of gene therapy research, focusing on clinically meaningful studies that combine patient observations with smart experiments. The approach of gene therapy may be applicable to all genetic disorders, offering a promising path for treatment and cure.
Wound Medicine, a new international journal, focuses on wound prevention, management, and reimbursement. The journal aims to advance science into clinical practice and improve patient outcomes through translational wound research.
Researchers found that peptides derived from soybean meal inhibit cancer cell growth by up to 73%, making it a potential nutraceutical for reducing colon, liver and lung cancer cell growth. This breakthrough could lead to the development of new cancer treatments.
New research published in the Journal of Theoretical Biology found that bumblebees are unstable when hovering and flying slowly, but become neutral or weakly stable at medium and high flight speeds. This is due to a sideways wind made by the movement of their wings, which can be reduced by increasing speed.
Researchers identified a rare variant in GRIN3A associated with schizophrenia, suggesting an intrinsic mechanism producing psychotic symptoms. The study supports the 'NMDA receptor hypothesis' and proposes a novel point of therapeutic intervention.
Researchers found that mice deficient in glutathione, a molecule essential for cellular protection against oxidations, had impaired parvalbumin neurons when stressed at young age. However, treatment with N-acetylcysteine from birth onwards protected these neurons, suggesting a potential preventive measure for psychiatric disorders.
Researchers found that repetitive transcranial magnetic stimulation (rTMS) improved working memory performance in individuals with schizophrenia, comparable to healthy subjects. The study suggests rTMS as a potential treatment for cognitive deficits in schizophrenia.
Researchers found that contaminated water used to dilute pesticides can carry human noroviruses, potentially contaminating the food chain. The study suggests that pesticide application may be a microbiological risk factor for public health.
A new study published in Biological Psychiatry found that antipsychotics with high binding affinity of alpha2 adrenergic and M1 muscarinic receptors are associated with a greater risk of stroke in elderly patients. The study also suggests that stroke risk is highest in the initial weeks of treatment and for those with higher daily doses.
A recent study found that nearly 90% of preschoolers with ADHD continued to struggle with symptoms six years after diagnosis. Children taking ADHD medication had just as severe symptoms as those who were medication-free, suggesting a need for improved treatment strategies.
Researchers have developed a new approach to screening potential treatments for Alzheimer's disease using the C. elegans worm model. The study identified six compounds capable of alleviating tau-induced behavioral abnormalities in the worm model, as well as azaperone treatment, which can decrease abnormal tau accumulation.
A new study suggests schizophrenia is associated with accelerated aging, particularly in cerebral white matter. Individuals with schizophrenia have shorter average lifespans and are at increased risk of cardiovascular illnesses.
A study found that family-focused treatment improved mood symptoms in children and adolescents at risk for bipolar disorder, with significant benefits for those from high expressed emotion families. The treatment showed promise in stabilizing symptoms and improving long-term outcomes.
Vulvar lichen sclerosus is a chronic inflammatory disease affecting genital areas, causing significant discomfort. The EMAS clinical guide provides advice on early recognition and treatment to prevent delay in management.
Research suggests that major life events can alter gene expression, leading to trans-generational effects on children's brain functions. This discovery has significant implications for understanding the causes of mood disorders and addiction.
A recent study published in Biological Psychiatry reveals that scopolamine can rapidly improve mood in depressed patients. Additionally, the drug shows promise as a treatment for anxiety disorders by disrupting contextual processing during extinction learning.
The Journal of Forensic Radiology and Imaging aims to provide a cutting-edge communication platform for professionals developing and utilizing imaging techniques in forensic analysis. Research published in the journal covers topics such as imaging technologies, education, and best practices in forensic radiology and imaging.
Researchers found that modafinil improved response inhibition in patients with initially poor impulse control, but had a detrimental effect in those with low initial impulsivity levels. The study suggests personalized medicine approaches may be necessary when prescribing modafinil for treatment of alcohol dependence.
Research finds heightened activity in brain circuits for negative emotions and reduced activation of emotion-suppressing circuits in borderline personality disorder, with reduced frontal brain activity unique to the condition. The study suggests improved emotion regulation skills may be normalized after successful treatment.
A new study by De Montfort University reveals worrying inconsistencies in how NHS hospital trusts in England define and report surgical site infections. The findings suggest that published rates do not accurately reflect the true scale of surgical infections, highlighting the need for improved data collection and reporting systems.
A new study in Biological Psychiatry suggests that reductions in ECT treatment have an economic basis, with a 43% drop in psychiatric inpatients receiving the procedure. ECT is being discontinued by US general hospitals, primarily due to cost and regulatory issues.
The latest issue of Reproductive Health Matters exposes the significant impact of neglected sexual and reproductive morbidities on women, men, and families globally. It addresses various health issues, including fistula complications, maternal health, and cervical cancer, while also highlighting prevailing myths and misconceptions.
Elsevier has launched a new open-access journal, Journal of Pediatric Surgery Case Reports, which will publish original, peer-reviewed case reports on unusual presentations and novel diagnostic and therapeutic techniques in pediatric surgery. The journal aims to provide high clinical interest and educational value.
Elsevier has acquired the Journal of Choice Modelling, a leading publication in choice modelling, which covers topics such as transport and marketing. The journal will continue to publish four issues in 2013 and maintain access for a wide range of readers through ScienceDirect.
Elsevier will publish the International Review of Economics Education (IREE) journal starting in January 2013, with an increased frequency from two to three issues per calendar year. The journal aims to enhance learning and teaching in economics education, promoting critical dialogue on educational theory and practice.
A new study published in the Journal of the American Academy of Child and Adolescent Psychiatry found that food insecurity is strongly associated with adolescent mental disorders. The study examined 6,483 adolescents aged 13-17 years and found that a one standard deviation increase in food insecurity was linked to a 14% increased odds ...
The International Society for the Social Studies has selected Elsevier as publisher for its journal The Journal of Social Studies Research, beginning in January 2013. The peer-reviewed journal will foster research dissemination and ideas related to social studies education.