New research suggests that statins can decrease inflammatory and thrombotic proteins in individuals with antiphospholipid antibodies, reducing the risk of blood clots and other complications. A prospective study found that fluvastatin significantly decreased protein levels in patients with APS, offering a potential new treatment option.
A new study estimates that antiphospholipid antibodies are associated with pregnancy loss, stroke, myocardial infarction, and deep vein thrombosis in up to 60,000 cases each. The research provides a rough snapshot of the prevalence of autoimmune antiphospholipid antibodies in patients with various health conditions.
A new study by Hospital for Special Surgery has revealed that corticosteroids are more effective than the expensive treatment hylan G-F 20 in providing pain relief to patients with thumb arthritis. Clinically meaningful pain relief was achieved with all three treatments, including a placebo injection.
Studies found that lupus patients who underwent knee replacement surgery experienced few adverse events, with outcomes similar to those of osteoarthritis patients. Rheumatoid arthritis (RA) patients also performed similarly after joint replacement surgery, with no significant differences in operation time or post-surgical complications.
A new study by Hospital for Special Surgery reveals that morbidly obese patients have similar pain and function outcomes to non-obese patients after total knee replacement surgery. The research challenges the long-held assumption that obesity is a contraindication to joint replacement, with patients achieving great outcomes.
Using regional anesthesia reduces need for blood transfusions and major complications in bilateral knee replacements, according to a new study. Patients receiving neuraxial anesthesia had lower rates of blood transfusions compared to general anesthesia.
A new study reveals that younger and healthier patients undergoing bilateral total knee replacements are actually becoming sicker, with rising complication rates attributed to obesity. The study found a 3% increase in pneumonia, pulmonary embolism, and nonmyocardial infarction cardiac complications over time.
Researchers at Hospital for Special Surgery are studying the use of platelet-rich plasma (PRP) and stem cells to treat tendon injury and degeneration. The goal is to develop an effective therapeutic strategy to improve healing and reduce complications in NFL players.
A recent JAAOS study highlights the success of nerve transfer surgery, particularly when patients are referred early. Nerve transfer surgeries can restore function to severely damaged nerves, and the study aims to raise awareness among healthcare providers about this treatment option.
A new study finds that immobilizing patients for longer periods after rotator cuff surgery may improve healing rates. The research used a rat model and found that immobilization improved tendon healing, reducing scar tissue and inflammation.
Researchers at Hospital for Special Surgery demonstrate the superiority of the All-Inside, All-Epiphyseal ACL Reconstruction (AE) technique in children. The AE procedure provides great knee stability and effectively controls joint stress without risking injury to growing bones.
A study by Hospital for Special Surgery researchers has demonstrated that women with a specific type of antibody are at risk for adverse pregnancy outcomes. The study found that antiphospholipid antibodies (aPLs), particularly lupus anticoagulant, increase the risk of complications such as fetal death, preterm delivery, and preeclampsia.
A study of half a million patients found that 3% require critical care services after hip and knee replacements. Hospitals should prepare for the growing number of orthopedic patients needing critical care, with risk factors including age, comorbidities, and anesthesia type.
Researchers discovered that the Notch pathway contributes to the development of rheumatoid arthritis by influencing the differentiation and function of inflammatory macrophages. The study also shows that drugs under development for cancer could potentially be used to treat RA.
The Osteoarthritis Summit identified gaps in research and proposed a new classification system to address the disease's complexity. Experts emphasized the need for multidisciplinary approaches and biomarkers to monitor disease progression, with potential solutions including weight loss interventions and integrated treatment strategies.
Researchers at Hospital for Special Surgery found that the OATS procedure provides a higher return to sport and longer lasting results compared to microfracture. The study showed that patients who underwent OATS had improved Marx activity levels, indicating they could perform more sports and athletic activities.
A study of 46 retrieved metal-on-metal total hip replacements found common damage patterns, including scratches and wear patches. The researchers aim to understand the mechanisms behind these failures and develop new implant designs to reduce wear and corrosion.
A study by researchers at Hospital for Special Surgery found that surgeons who have performed less than 60 ACL reconstructions are roughly four to five times more likely to undergo a subsequent ACL reconstruction. The learning curve for ACL surgery is complex, and training programs may not be adequate to prepare young surgeons.
A study found that lupus patients with low socioeconomic status often miss appointments due to transportation and childcare issues. The researchers suggest improving transportation services or temporary childcare as a potential approach to ensure these patients receive necessary care.
A new study found that rheumatoid arthritis patients who undergo total knee replacement surgery have lower expectations about their postsurgical outcomes compared to osteoarthritis patients. This can lead to worse outcomes due to reduced motivation for rehabilitation, resulting in decreased function and overall quality of life.
Women with lupus can safely carry out pregnancy thanks to recent advances in rheumatology research, according to a study led by Jane Salmon. The study found that 80% of patients had a favorable pregnancy outcome when they had inactive lupus at the time of conception.
A multicenter NIH-funded study found that most women with stable lupus can have successful pregnancies, with 80% of patients experiencing favorable outcomes. The study's findings highlight the importance of timing and avoiding pregnancy during periods of increased disease activity.
A new study by Hospital for Special Surgery suggests that mental health is a risk factor for disease flares in patients with vasculitis, a devastating form of the disease characterized by inflammatory destruction of blood vessels. Patients who experience stress are 19% more likely to experience a flare-up.
Researchers found that patients taking anti-TNF medications for rheumatoid arthritis had a higher rate of post-surgical flares, but no significant increase in infections or complications. The study suggests that adjusting medication withdrawal timing based on individual half-lives may minimize disease flares
Researchers identified patients at increased risk after bilateral knee replacement surgery due to congestive heart failure, pulmonary hypertension, age over 75, and male gender. The study suggests that these patients should not be considered high-risk candidates for this elective procedure.
Researchers found that obese patients developed respiratory insufficiency (RI) and adult respiratory distress syndrome (ARDS) less frequently, with lower in-hospital mortality rates. Fatty tissue may act as a sink for inflammatory proteins, neutralizing them and reducing the inflammatory process.
Researchers found significant improvements in hip flexion (3.8 degrees) and internal rotation (9.3 degrees) after arthroscopic treatment for femoro-acetabular impingement, restoring range of motion across the joint.
Researchers identified patients with high femoral anteversion who experience poor surgical outcomes for snapping psoas tendon treatment. This study suggests that releasing the psoas tendon in these patients may result in delayed return to activities and inferior outcomes.
Researchers found that maintaining vitamin D levels above 33 ng/ml significantly improves outcomes in patients taking bisphosphonates for osteoporosis and low bone mineral density. The study supports optimizing vitamin D levels to improve treatment effectiveness.
A recent study published in Nature Immunology has discovered a novel mechanism by which tumor necrosis factor (TNF) suppresses inflammatory responses. The researchers found that TNF activates the glycogen synthase kinase 3-alpha protein and upregulates the A20 gene, leading to reduced inflammation.
Researchers developed a tool to measure outcomes of brachial plexus surgery, which is currently inconsistent and difficult to compare. The new tool aims to standardize reporting, helping clinicians advance the science and improve patient care.
Researchers found that modern spinal fusion techniques do not cause significant damage to the spine just below the fused discs, contrary to previous beliefs. Patients who underwent surgery showed good functional scores, balance maintenance, and minimal lower back pain ten years post-operatively.
A Phase II trial of Gleevec (imatinib) has shown acceptable safety and tolerability, with hints of efficacy in treating diffuse scleroderma. The drug improved skin scores by 22% and forced vital capacity scores by 6.4% after 12 months of therapy.
Researchers identified genetic mutations in women with lupus and/or antiphospholipid antibodies that may predispose them to preeclampsia. The study's findings suggest new targets for treating the condition and raising the possibility of tests to identify women at increased risk
A large prospective study found that arthroscopic rotator cuff repair is highly effective at restoring function, with improved ASSE scores and motor grades over time. The study also showed that some tendons can heal fully within five years after initial incomplete healing.
Researchers found that athletes with symptomatic femoro-acetabular impingement (FAI) had a higher incidence of athletic pubalgia and sports hernias. Treating the underlying hip condition can resolve symptoms, allowing patients to return to play.
A new study identified key factors influencing a dancer's ability to return to work after hip arthroscopy. The study found that younger age, modern dance training, and less degeneration of the articular cartilage were predictors of success, while ballet dancers and those with hip dysplasia or Cam impingement had lower rates of return.
Patients who undergo elective orthopedic surgeries at high-volume hospitals have better surgical outcomes and fewer complications than those at local hospitals. Regionalizers, or patients traveling to regional high-volume hospitals, tend to be younger, white, male, and have private insurance.
A recent study by Hospital for Special Surgery investigators found no improvement in tendon healing after rotator cuff repair using platelet-rich fibrin matrix. The study's findings question the premature use of PRP in some cases, highlighting the need for further research on dosing and timing.
A recent study published by Hospital for Special Surgery found that knee replacement surgeries take significantly longer and cost more for overweight patients. The researchers analyzed data from 454 patients and found that as body mass index increased, so did the time it took to perform all parts of the surgery.
Sleep-deprived physicians may perform procedures with potentially severe consequences, compromising patient care. Patients deserve informed consent and the option to reschedule or choose a different provider if necessary.
A new assessment tool, SMILEY, helps shed light on the quality of life of children with lupus around the world. The study found that parents and children perceive the disease differently, with Asian countries reporting a better quality of life than Europe or South America.
The Mary Kirkland Center offers personalized care to lupus patients through a team of healthcare professionals. The center provides education and research opportunities, as well as programs addressing cardiovascular health and wellness, to improve patient outcomes.
Researchers identified advanced stage cancer as the key factor predicting joint pain in breast cancer patients on aromatase inhibitor therapy. The study also found that tenosynovitis, inflammation of tendon sheaths, was present in some symptomatic subjects, but no correlation with depression or autoimmune markers was observed.
A recent study identified factors that increase the risk of falls among orthopedic inpatients, particularly those undergoing total hip replacements. The study found that THR patients are more likely to have serious falls earlier in their stay, highlighting the need for close monitoring and vigilance.
Researchers present advances in preventing falls in orthopedic patients, improving quality of life in children with lupus, and understanding joint pain caused by breast cancer medication. The hospital also recognizes three faculty members as masters at the American College of Rheumatology Annual Meeting.
A study by Hospital for Special Surgery reveals that vitamin D deficiency affects up to 50% of patients undergoing orthopedic surgery, hindering bone healing and muscle function. Researchers recommend correcting deficient levels before surgery to improve patient outcomes.
A new study overturns popular perception that patients undergoing osteochondral allograft transplantation cannot return to sports. The study found that 84% of patients can return to some level of athletic activity and 60% can return to high-level sports.
A study presented at the American Orthopaedic Society for Sports Medicine meeting found that nearly 80% of patients who underwent arthroscopic surgery for femoro-acetabular impingement (FAI) were able to return to play at a high level of competition, with an average recovery time of 9.4 months. The study showed significant improvements...
A new study found that Rituximab can effectively treat severe vasculitis, reducing the risk of infertility and cancer compared to traditional medication. The treatment was shown to be equally effective in putting patients into remission as cyclophosphamide, with a safer side effect profile.