Patients with stage IV flat foot deformity experience improved alignment, reduced arthritis, and enhanced mobility after a new surgery developed at Hospital for Special Surgery. The study shows promising results, including the maintenance of correction nine years post-surgery.
Researchers at Hospital for Special Surgery have discovered a new pathway involved in turning off inflammation that does not work properly in people with inflammatory arthritis. This finding could lead to the development of new therapeutic approaches to treating arthritis.
A new mobile compression device has been shown to be as effective as medication in preventing blood clots after hip replacement surgery, with greater patient safety. The device reduces the risk of clot formation by maximizing blood flow and is comparable in cost to traditional blood thinners.
A study by Hospital for Special Surgery found that Forteo can enhance tendon to bone healing, leading to better repair results. The researchers used a rat model to test the effects of Forteo on rotator cuff surgery and achieved promising results, including improved tissue organization and strength.
A new study found that joint replacement surgeries often fail to align patient and doctor expectations, resulting in higher dissatisfaction rates. The study suggests that educational interventions like preoperative classes can be used to improve dialogue between patients and surgeons.
Dr. Adele Boskey, a renowned researcher in orthopedics, has been awarded the ORS/AOA Alfred R. Shands, Jr. Award for her lifetime contributions to the field. Her research focuses on bone quality and osteoporosis, with a goal of decreasing fracture risk through a deeper understanding of bone biology.
Researchers have identified a biomarker that can help predict which patients with rheumatoid arthritis are likely to benefit from therapy with TNF-antagonist drugs. The study found that patients with higher baseline levels of type I interferon and increased IFN-beta/alpha ratio were more likely to respond to therapy.
Researchers at Hospital for Special Surgery used a novel technique involving transplanted bone and cartilage to treat an 18-year-old man's severe femoral head fracture. The patient successfully recovered from the surgery and delayed his need for a total hip replacement, avoiding multiple revision surgeries.
Researchers have identified a new therapeutic approach for proliferative crescentic disease, a type of advanced kidney disease associated with lupus. The study suggests targeting macrophages and growth factors involved in the disease mechanism.
Researchers found that the natural grass/cleat combination placed a statistically lower maximum strain on the leg compared to other shoe-surface interactions. The Astroturf shoe was 80.2% greater, while modern playing turf/turf shoes were 47.5% and 45.1% greater than the natural/grass cleat combination.
A recent study by researchers at Hospital for Special Surgery identifies four key areas of need for orthopedic training programs: addressing compromised learning experiences due to work-hour restrictions, developing core knowledge with specific goals, establishing common benchmarks for program effectiveness, and adapting to generationa...
Researchers have identified a drug that could provide the first treatment for scleroderma, a chronic connective tissue disease. In a study of 30 patients with diffuse scleroderma, Gleevec improved skin scores by 23% and lung function tests by 9.6% after one year.
A new study by Hospital for Special Surgery investigators finds that most lupus patients are not aware of their increased risk for cardiovascular disease, but a counseling program helps them make informed lifestyle choices. The program has been well-received by patients, with over 90% satisfaction rates.
A study found that 6.5% of ACL surgery patients underwent another knee operation within one year, with women and those treated by low volume surgeons at higher risk for subsequent surgeries. Younger patients under 40 were also more likely to require re-ACL reconstruction.
Scientists discovered that downregulation of IRF-8 gene increases production of osteoclasts responsible for bone breakdown. The study found that IRF-8 suppresses osteoclast activity and inhibits NFATc1 protein function, potentially leading to new therapeutic approaches.
Researchers at Hospital for Special Surgery have developed a biodegradable scaffold to treat patients with damaged knee cartilage. The study found that the plug demonstrated predictable maturation on imaging studies and showed encouraging properties similar to native articular cartilage.
Researchers used motion analysis to study the kicking motion in male and female soccer players, finding that males have more activation in hip flexors and hip abductors compared to females. Female players also exhibit a knock-kneed knee position, which may contribute to increased ACL injuries.
Researchers at Hospital for Special Surgery have identified a drilling technique that improves the outcome of ACL surgery by better reproducing the native ligament anatomy. The anteromedial portal drilling technique outperforms the traditional transtibial technique in restoring knee stability and preventing complications.
A study published in the Journal of Ultrasound in Medicine found that portable ultrasound was clinically beneficial in urban and rural settings in Ghana. The technology offered a range of applications, including musculoskeletal, obstetrical, and abdominal examinations, with 81% of performed ultrasounds being abnormal.
Researchers at Hospital for Special Surgery have identified a potential new therapeutic target for treating inflammatory disorders like rheumatoid arthritis. Manipulating the protein RBP-J could serve as a treatment, leveraging gamma secretase inhibitors already in trials for leukemia.
Researchers at Hospital for Special Surgery found that women with stable or mildly active lupus have relatively infrequent flares during pregnancy and deliver healthy babies. The PROMISSE study identified factors to help plan a low-risk pregnancy, including monitoring antiphospholipid antibodies.
Researchers at Hospital for Special Surgery found that statins can prevent white blood cell activation and protect pregnancies in women with APS. The study suggests that statins may be used as a treatment for women with APS-induced pregnancy complications.
A study found no benefit of arthroscopic surgery for osteoarthritis, but an expert argues it has a place in specific cases. Arthroscopy is valuable for patients with co-existing knee injuries, such as meniscal tears or loose cartilage.
Research from Hospital for Special Surgery found that individuals born with a birthweight over 10 pounds are twice as likely to develop rheumatoid arthritis as those with average birthweight. A study of 87,077 women identified a significant association between high birthweight and rheumatoid arthritis.
A study by Hospital for Special Surgery found that same-day pregnancy testing reduces the risk of miscarriage during surgery, allowing patients to weigh the risks and benefits. The protocol also eliminates financial losses due to cancelled surgeries, making it a cost-effective measure for hospitals.
Researchers at Hospital for Special Surgery discovered a new mechanism involved in the pathogenesis of inflammatory diseases such as rheumatoid arthritis. The study reveals that tumor necrosis factor (TNF) activates macrophages to produce interferon-beta, leading to sustained expression of genes encoding inflammatory molecules.
A new British hospital reduced its infection rate from 1% to 0.16% and length of stay by an average of five days, thanks to collaboration with Hospital for Special Surgery.
Researchers have discovered two new targets for drugs aimed at controlling lupus by regulating the balance between inflammatory and antiviral effects of interferons. By blocking specific kinases in the calcium-signaling pathway, they were able to suppress STAT1 activation and preserve antiviral effects.
Researchers found a genetic link between high levels of interferon-alpha and an increased risk of developing lupus. The study suggests that individuals with high interferon-alpha levels may be more likely to develop the disease, especially if triggered by environmental factors.
New imaging technologies provide non-invasive diagnostic tools for orthopedic conditions, allowing for early disease detection and objective outcome measures. These technologies enable precise quantification of bone loss and synovial reaction in osteoarthritis, facilitating more effective treatment strategies.
New cartilage repair techniques have been shown to improve knee function and reduce pain in patients. Studies using osteochondral allografts and microfracture procedures resulted in better outcomes, including increased knee function and reduced pain, after a minimum of two years.
Dr. Adele Boskey, a researcher at the Hospital for Special Surgery, has been elected as an AAAS Fellow for her significant work on biological calcification and extracellular matrix proteins. She was recognized at the 2005 AAAS Annual Meeting in Washington, DC.
A new study found that pain medications NSAIDs and COX-2 inhibitors can slow healing after shoulder surgery. The research used laboratory rats to test the effects of these medications on tendon-bone healing.