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Imperial College London


Chromosome 'caps' predict bone marrow disease

Researchers at Imperial College London have discovered a link between chromosome 'caps' and the prediction of rare bone marrow diseases. The study found that shorter telomeres in chromosomes can indicate an increased risk of disease severity and early onset, providing a potential new mechanism for understanding disease anticipation.

SourceImperial College London·JournalNature Genetics·DateApr 18, 2004

Scientists develop greater accuracy in recording baby’s heart rates in the womb

Researchers have developed a new test that can accurately record baby's heart rates in the womb in just 20 minutes, allowing doctors to monitor health and detect potential arrhythmias. The technique uses sophisticated filtering and signal processing technologies to pick out the baby's heart signal from background interference.

SourceImperial College London·JournalBritish Journal of Obstetrics and Gynaecology·DateAug 11, 2003

'Pachinko chances'

A new theory suggests that human metabolism operates like a pinball machine, influencing drug toxicity and disease development. The researchers used metabonomics to study global human metabolism and its interactions with drugs, environment, and gut microflora.

SourceImperial College London·JournalNature Reviews Drug Discovery·DateAug 1, 2003

First population study of GM mosquitoes highlights difficulties facing malaria control technique

A recent study by Imperial College London found that genetically modified mosquitoes (GM) lose their test marker gene rapidly when interbred with unmodified mosquitoes, posing challenges for malaria control. The researchers suggest using crossing regimes to minimize deleterious mutations and improve the competitiveness of GM mosquitoes.

SourceImperial College London·JournalScience·DateFeb 20, 2003