Shinya Yamanaka has developed a method to reprogram adult skin cells into pluripotent stem cells, eliminating the need for embryos. This breakthrough will aid research into preventing birth defects and improving baby health.
A recent study found that fertility drugs contribute significantly to the growing problem of premature births in the US. The March of Dimes urges more research and leadership to develop specific guidelines for the proper use of these drugs.
The US received a 'D' grade on the March of Dimes Premature Birth Report Card, with over half a million newborns not receiving a healthy start. Seven states improved their preterm birth rates by reducing smoking, uninsured rates, and late preterm births.
Dr. Gail Harrison receives the March of Dimes Agnes Higgins Award for her groundbreaking research on maternal-fetal nutrition, particularly in developing countries. Her work has led to advances in understanding fetal growth and the importance of nutrient-rich diets during pregnancy.
The March of Dimes has established two new awards to honor established scholars in perinatal ethics and encourage young researchers to enter the field. These awards will focus on moral issues before, during, and after pregnancy, including reproductive technologies and neonatal care.
The new White Paper reveals an estimated 13 million babies worldwide were born preterm in 2005, with one million deaths attributed to preterm birth. Premature births face serious lifelong health risks and contribute significantly to global healthcare costs.
A study published in PLOS Medicine found that women who take folic acid supplements for at least one year before becoming pregnant are less likely to have premature babies. The research suggests a significant reduction in very early and early preterm deliveries, with a 70% decrease in the most high-risk category.
The March of Dimes has awarded a $250,000 prize to Kevin P. Campbell and Louis M. Kunkel for their pioneering work identifying the genes and proteins that cause muscular dystrophy. Their research has led to better diagnostic tools and potential treatments, improving the lives of over 250,000 Americans affected by the disorder.
Dr. Roberta A. Pagon, a renowned medical geneticist, has received the March of Dimes/Colonel Harland Sanders Award for her groundbreaking work in developing the public database genetests.org, which helps doctors analyze genetic tests for making informed medical decisions.
The medical cost of caring for one premature baby can reach nearly $50,000, exceeding the cost of caring for a dozen healthy full-term infants. This highlights the importance of preventing preterm birth and improving maternal healthcare to reduce healthcare costs and save lives.
Nearly all US babies are now screened for 21+ life-threatening disorders, thanks to increased mandates and advocacy efforts. This expansion has significantly improved public health outcomes.
The March of Dimes has awarded nearly $14 million in grants since 2009 to support innovative research on preterm birth. Researchers will investigate microbes, enzymes, and genetic factors to identify risk factors for prematurity and develop strategies to prevent it.
Research finds that genetic variation in progesterone receptor affects 17P treatment response, with predictive SNPs identified for African-American and non-African-American women. Progesterone treatment may be less effective in some women due to genetic predisposition.
A recent survey by March of Dimes found that only 17% of Spanish-speaking women of childbearing age take a multivitamin containing folic acid daily. Folic acid is crucial in preventing neural tube defects (NTDs), which are more prevalent in the Hispanic population.
A recent study published in the Journal of Pediatrics found that babies born just a few weeks prematurely are three times as likely to have cerebral palsy and developmental delays. The research analyzed medical records of over 140,000 children born in California between 2000 and 2004.
The US received an overall 'D' grade on the first Premature Birth Report Card, with 18 states and Puerto Rico receiving failing grades. The report highlights contributing factors and prevention opportunities, including smoking and uninsured women of childbearing age.
Research found that mothers who smoked during pregnancy were more than twice as likely to have a baby with a cleft palate or lip. Nearly 7,000 babies are born annually with oral-facial clefts in the US, which can lead to feeding difficulties and other health issues.
The March of Dimes has launched a national petition to reduce the rate of premature birth, which affects over 530,000 babies each year. The four-point petition calls for hospitals to review cesarean-section births and inductions before 39 weeks gestation to prevent early deliveries.
Researchers have induced pre-eclampsia in mice by injecting human autoantibodies, demonstrating a potential pathway for the disorder. Blocking these autoantibodies prevented the development of pre-eclampsia in mice, suggesting a new approach to diagnosis and treatment.
A new analysis by the March of Dimes found that nearly all increases in singleton preterm births in the US are due to c-section deliveries. Late preterm babies account for most of this rise, with a greater risk of complications such as breathing problems and delayed brain development.
A new analysis of nearly 7 million US live births found that babies born preterm were more than twice as likely to have major birth defects. The study also showed that very preterm babies, those born between 24-31 weeks gestation, were five times more likely to have a birth defect.
Researchers Philip A. Beachy and Clifford J. Tabin received the 2008 March of Dimes Prize for their work on hedgehog genes and their role in embryonic development, including limb formation and organ development.
Dr. Peter H. Byers has received the March of Dimes/Colonel Harland Sanders Award for Lifetime Achievement in Genetics for his groundbreaking research on collagen gene mutations and their role in inherited disorders such as Ehlers-Danlos syndrome and osteogenesis imperfecta. His work has significantly advanced our understanding of these...
The March of Dimes has awarded $3.5 million to scientists studying the role of genes and heredity in premature births. The organization aims to understand the causes of preterm birth, which affects over half a million babies annually.
A new study suggests that taking folic acid supplements for at least one year before pregnancy can significantly reduce the risk of premature birth. The research found a 50-70% decrease in early preterm deliveries, with the greatest reduction seen in very early premature births.
A new Folic Acid for a Healthy Pregnancy seal will help women easily identify grain products with folic acid. The seal aims to increase consumption of the essential nutrient among women of childbearing age, reducing neural tube defects by 26% since 1998.
A new study published in the Journal of Pediatrics reveals that babies born just a few weeks premature are at increased risk of death during their first week of life. The study found that late preterm infants face a six-fold higher mortality rate compared to full-term infants.
Two studies published in The New England Journal of Medicine found that progesterone treatment reduced the rate of preterm birth among women with short cervix. However, weekly injections of 17P did not show similar benefits for women carrying twins. Researchers hope to identify underlying causes of prematurity to improve progesterone t...
A report by the March of Dimes Foundation reveals that 122 pregnancies were exposed to Accutane despite a mandatory risk management program. The program, known as iPledge, aims to prevent pregnant women from being exposed to isotretinoin, a known teratogen.
The March of Dimes reports that nearly 90% of US babies are screened for life-threatening disorders, up from 38% in 2005. However, 500,000 babies remain uninsured, highlighting the need for federal guidelines and increased funding to support states' newborn screening programs.
Two studies published in The New England Journal of Medicine found taking SSRIs during pregnancy increases the risk of rare birth defects, including withdrawal symptoms and pulmonary hypertension. However, most birth defects were not associated with antidepressant use.
Janet Rossant and Anne McLaren receive March of Dimes Prize in Developmental Biology for their pioneering work on mammalian reproduction and development using the mouse model. Their research has significantly advanced understanding of birth defects, genetic predispositions, and reproductive technology.
The March of Dimes and Johnson & Johnson Pediatric Institute have launched a three-year partnership to reduce preterm births in targeted areas of Kentucky. The goal is to decrease singleton preterm births by 15%, with a focus on interventions combining clinical care, public health, and education.
Dr. Kenneth Lyons Jones, a pioneering researcher, has received the 2007 March of Dimes/Colonel Harland Sanders Award for his groundbreaking work on dysmorphology and fetal alcohol syndrome. His research has focused on identifying mechanisms of normal and abnormal fetal development.
A new study by the March of Dimes Foundation finds that high-dose progesterone treatment can significantly reduce the risk of preterm delivery in pregnant women who have previously experienced premature labor. The treatment appeared to prevent cervical shortening and inflammation, key factors contributing to premature birth.
The March of Dimes has allocated $3 million to support eight scientists' research on predicting and preventing preterm birth. Five projects focus on immune responses, while others investigate the role of genetic factors, circadian rhythms, and potassium balance.
The March of Dimes and the Johnson & Johnson Pediatric Institute launched a three-year Prematurity Prevention Initiative in Kentucky to test bundling proven interventions and reduce preventable preterm births. The initiative aims to provide expectant mothers, families, and healthcare professionals with comprehensive support and education.
The American Society of Reproductive Medicine recommends limiting embryo transfers during in-vitro fertilization procedures to one, reducing the risk of complications for both mother and fetus. The goal is to decrease higher-order multiple gestations and their associated preterm birth risks.
A new study published in Pediatrics found that preterm birth caused over one-third of infant deaths in the first year of life. The study used a new method to classify causes of infant death and found that premature birth was the leading cause, followed by birth defects.
Research emphasizes the importance of preconception care in reducing pregnancy risks, birth defects, and premature birth. Experts recommend discussing reproductive health with doctors during routine visits.
A commercial progesterone therapy appears to prevent some premature births, with a 33% reduction in preterm birth rate for women who had a previous premature baby. The March of Dimes estimates that if all eligible women received the therapy, nearly 10,000 premature births might have been prevented.
Two genetic markers, one associated with African American babies and the other with women with chronic hypertension, have been identified as potential predictors of preterm birth. The findings could lead to improved diagnosis, prevention, and treatment of preterm birth, reducing its risks for lifelong health complications.
The March of Dimes calls for passage of federal PREEMIE Bill to address prematurity, with severe health consequences and significant economic burden estimated at over $26.2 billion annually. The organization supports increased research investment and public awareness campaigns to prevent premature birth.
Dr. Varshavsky's pioneering studies revealed ubiquitin's diverse roles in cell cycle, DNA repair, and responses to stress, advancing the field of molecular genetics. The March of Dimes Prize acknowledges his significant contributions to understanding birth defects, neurodegenerative syndromes, cancer, and immune disorders.
The typical pregnancy duration has decreased to 39 weeks, leading to a rise in late preterm births. Late preterm infants face increased risks of breathing problems, feeding difficulties, and reduced brain development compared to full-term babies.
The March of Dimes has awarded $2.4 million in grants to six innovative scientists working on new ways to identify women at increased risk for premature birth and understand the role of inflammation and progesterone in triggering labor. The goal is to prevent premature births, which are the leading cause of newborn death in the US.
Researchers have developed a new test that can predict fetal complications from intrauterine inflammation/infection, providing faster results and higher accuracy than traditional methods. The test uses proteomic profiling of amniotic fluid to identify biomarkers of inflammation, allowing for early intervention and potentially reducing ...
The March of Dimes Global Report reveals that at least 3.3 million children under 5 years old die annually due to serious birth defects, with an estimated 3.2 million surviving with lifelong disabilities. The report highlights the global toll of birth defects on mortality and disability rates in middle- and low-income countries.
The study found that cleft lip and/or palate had the highest prevalence, followed by Down Syndrome, among the 18 major birth defects studied. National estimates for specific defects were calculated for the first time, providing valuable insights into birth defect prevalence nationwide.
Despite nationwide efforts, only two-thirds of women ages 18-45 are taking folic acid supplements daily. The March of Dimes calls for increased grain fortification and multivitamin use to reduce neural tube defects.