Researchers have discovered a new pathway for intercellular exchange of large cell structures, enabling genetic material to be transferred between plants. This process allows for the creation of new plant species and has implications for crops like bread and durum wheat.
Researchers have discovered a new material that exhibits both charge density wave and topological metal properties, featuring Weyl points and immense chiral charges. The discovery reveals an intimate connection between topology and electron correlations, opening up avenues for observing axion electrodynamics in condensed matter systems.
Researchers have engineered a new-to-nature metabolic connection, the TaCo pathway, which fixes CO2 instead of releasing it in photorespiration. This synthetic pathway is more energy-efficient than any other proposed alternative, with potential applications in improving crop yield and recycling polyethylene terephthalate (PET).
Researchers combined psychiatric assessments with machine learning models to predict mental illness, improving disease course prediction and intervention timing. The algorithm assists decision-making and provides recommendations for targeted interventions.
Researchers found that glycylation, a rare modification of tubulin protein, is essential for maintaining straight swimming motion in sperm cells. Without this modification, sperm swim in circles due to uncoordinated activity of molecular motors.
An international team of scientists has developed a novel technique for a high-brightness coherent and few-cycle duration source spanning 7 optical octaves from the UV to the THz. This breakthrough enables future research on time-domain analysis of substances, opening new opportunities for multimodal measurement approaches.
A new study decodes the molecular diversity of neurons in the zebrafish retina, identifying at least 32 different types of retinal ganglion cells. These cell types are linked to specific functions and behaviors, shedding light on how the brain processes visual stimuli.
Researchers developed a compound that inhibits the growth of cancer cells by targeting mitochondrial function, without severe side effects. The compound prevents genetic information within mitochondria from being read, starving cancer cells into dying.
A global analysis of bird songs reveals that size, not habitat type, is the primary driver of song frequency. The study also suggests that males with larger bodies produce lower-frequency songs due to competition for mates.
A team of researchers has successfully grown structures similar to parts of a mouse embryo using a special gel and 3D cell culturing technique. This allows for the investigation of pharmacological agents on a scale that would not be possible in living organisms.
Researchers used connectomic mapping to study inhibitory neuronal circuitry in developing mice brains. They found that different types of interneurons followed distinct developmental time courses to establish synaptic partners.
Researchers found a brain molecule called Pth2 that changes expression levels in response to social conditions. When zebrafish are isolated, Pth2 disappears, but its levels rapidly rise when they're added back into a group, indicating a 'thermometer' effect.
A study on vulturine guineafowl found that democratic decision-making allows subordinate birds to lead the group away from dominant-controlled food patches, forcing dominants to abandon their rich resources. This mechanism helps maintain a balance of power in the group, ensuring all members can access essential resources.
Researchers identified Sestrin as a key regulator of stem cell function and lifespan in response to dietary amino acids. Increasing Sestrin levels extended fruit fly lifespan and protected against negative diet effects.
Researchers applied CRISPRi technology to understand metabolic robustness in E. coli, revealing mechanisms that buffer enzyme knockdowns. The study identified specific buffering mechanisms across multiple metabolic pathways, paving the way for developing industrially useful microbes with controlled metabolism.
Scientists have found that surface diffusion of proteins is more effective at providing proteins to distal dendritic sites, reducing the need for protein production. By optimizing dendritic radii, neurons can reduce their protein synthesis cost by several orders of magnitude.
A new study by Max-Planck-Gesellschaft scientists has identified a region of the thalamus as a key source of signals encoding past experiences in the neocortex. This discovery sheds light on how the brain forms sensory memories, which are essential for perceiving our environment and interacting with it.
Researchers found that RNA from repetitive elements activates RIG-I-like receptors, inducing inflammation and increasing hematopoietic stem cell numbers. The RIG-I-like receptor family plays a crucial role in regulating hematopoiesis, with different members having opposing effects on developmental hematopoiesis.
The Arctic Animal Movement Archive provides a global dataset of animal migration patterns, revealing changes in behavior and ecosystem responses to climate change. Studies have found that golden eagles arrive earlier in spring following mild winters, while caribou herds are giving birth earlier in the north.
Researchers at the Heidelberg Max Planck Institute for Nuclear Physics have investigated ultrafast fragmentation of hydrogen molecules in intense laser fields using a new method. They used the rotation of the molecule as an internal clock to measure the timing of the reaction triggered by a second laser pulse.
Researchers develop model that links movement of predators and prey to segregation of oil and vinegar, expanding theoretical framework from inanimate matter. The model reveals universal characteristics of active living matter, including bacteria, enzymes, and motor proteins.
Researchers found that serotonin can stimulate the production of basal progenitor cells in the fetal human brain, potentially contributing to the evolutionary expansion of the neocortex. This new function of serotonin may help explain the development of neurodevelopmental and psychiatric disorders.
Astronomers have found compelling evidence that planets start to form while infant stars are still growing. The ALMA radio observatory has captured a high-resolution image of the proto-star IRS 63 with multiple gaps and rings of dust, indicating that seeds of planets are forming in these cosmic cradles.
Researchers Nathalie Picque and Theodor Hänsch developed dual-comb spectroscopy to detect spectral patterns even in extremely low light conditions. This technique enabled the recording of broad spectra with over 100,000 colors in near complete darkness.
Researchers have found a new way to make leukemic stem cells vulnerable by specifically dislodging them from their niches, allowing for potential treatment against chronic myeloid leukemia. The approach uses an RNA molecule complex to prevent the cancer stem cell's retention in its tumor-supporting niche.
The study elucidated how Rubisco activase works, revealing that it grabs the N-terminal tail of Rubisco and releases inhibitory sugar molecules using ATP energy. This dual function enables Rca to recruit into carboxysomes, where CO2 is generated, making photosynthesis more efficient.
Researchers have identified volatile organic compounds used for olfactory navigation by homing pigeons, generating regional olfactory maps that can be used as a compass to return home from unfamiliar sites. The study provides evidence for the existence of suitable regional chemical gradients in the air.
A multidisciplinary team has successfully visualized superficial white matter in living human brains using high-field MRI. The study reveals that this region contains significant amounts of iron, necessary for myelination, which can occur throughout lifespan but is predominant during development.
A specific region of messenger RNAs plays a crucial role in brain cell function. The study reveals an unusual EXAR (EXon-Activated Rescue) mechanism that secures this process, using ELAV and FNE proteins to determine neuronal transcript signatures.
Researchers have developed a chip-based technology that generates high-resolution sound profiles with intense sound pressure. This allows for more effective and easier ultrasound therapy, potentially benefiting patients with cancer, brain conditions, and other diseases. The technology also enables the creation of organoid models for dr...
Researchers have successfully sequenced the Y chromosomes of Neandertals and Denisovans, shedding light on their genetic relationships. The findings reveal that Neandertals had adopted male sex chromosomes from modern humans, with similar patterns seen in mitochondrial DNA.
Researchers found a strong linear relationship between societal generosity and life expectancy. Societies with higher transfer payments have lower mortality rates, particularly in Western European countries and Japan.
Researchers discovered a metabolic adaptation in nerve cells that allows them to counteract degeneration and promote survival. This 'metabolic rewiring' involves the activation of the Krebs cycle anaplerosis pathway, which makes neurons resistant to progressive damage.
A new study by Max Planck Institute researchers found that the risk of cognitive impairment and dementia in US men and women increased over two decades. The analysis controlled for learning effects when repeating the same test, revealing a trend reversal compared to previous studies.
Scientists selectively bred zebrafish to exhibit distinct personality traits, finding that brain activities soon changed and new brain regions were activated. The study suggests a rapid pace of personality trait changes and potential implications for human behavior.
Scientists discovered that identifying tumor-associated macrophage patterns in lung tumor tissue enables the prediction of disease progression. The study found that a higher number of tumor-promoting macrophages near the invasive margin is associated with lower patient survival rates.
Researchers at Max Planck Institute for Molecular Genetics discovered that epigenetic regulators control the development of different tissues and organs in early mouse embryos. By analyzing thousands of individual cells, they found that specific regulators have unique functions in every cell, making them difficult to study.
The study reveals changes in hearing genes that contribute to echolocation, expansions of anti-viral genes, and loss of inflammation genes in bats. The high-quality bat genomes provide a genomic record of historical tolerance to viral infection and may hold the key to alleviating human ageing and disease.
Researchers at Max-Planck Institute for Terrestrial Microbiology study signal transmission in baker's yeast to understand how cells balance information accuracy with energy costs. They found that the pheromone signalling pathway contains negative feedback regulations that improve accuracy, but may also impose fitness costs.
Researchers discovered ferroelastic twin domains in perovskite crystals that can influence electron movement. These structures, or 'electron highways,' could make perovskite solar cells more powerful and improve their efficiency.
Scientists have discovered a specific circular RNA that prolongs fruit fly lifespan by regulating the insulin signalling pathway. The circRNA, called circSulfateless, is expressed at higher levels in long-lived flies and can directly influence their lifespan. These findings suggest a potential link between circRNAs and human ageing.
Researchers measured gas motions throughout the Milky Way and a nearby galaxy, finding that cold molecular gas motions appear to fluctuate in velocity, reminiscent of ocean waves. The team discovered that equidistantly spaced structure shows distinctive pattern, with periodic spacing likely resulting from gravitational instability.
Researchers suggest Epo may mitigate severe disease progression and protect patients from neurological effects in Covid-19. Initial case studies indicate a positive effect of Epo treatment, with one patient showing rapid recovery after treatment.
Researchers found that animals exhibited unusual behavior up to 20 hours before earthquakes, with stronger reactions closer to the epicenter. The movement data were evaluated using statistical models, suggesting a potential for an animal-based earthquake early warning system.
A global initiative is investigating how animals are responding to reduced levels of human activity during the Covid-19 pandemic, revealing insights into human-wildlife interactions. The study aims to improve understanding of space sharing on a crowded planet with benefits for both wildlife and humans.
Researchers find that the human-specific gene ARHGAP11B causes an enlarged neocortex in common marmosets, a non-human primate. The study suggests that this gene may have played a key role in the expansion of the human neocortex during evolution.
Researchers have developed a CRISPR-Cas9 method to optimize proteins in mammalian cells, producing the fluorescent protein mCRISPRed that labels lysosomes. This technique enables targeted protein diversification and validation within organelles, opening new possibilities for biosensors, receptors, and therapeutic proteins.
A climate game developed by Max Planck researchers shows that global cooperation can be possible -- although not without effort. The study found that richer countries rarely stopped climate change and migration, while poorer countries supported a minimum level of climate protection.
Research at Max Planck Institute for Biology of Ageing reveals that NFYB-1 regulates mitochondrial function through lysosomal prosaposin, a key factor in cellular longevity. The study used Caenorhabditis elegans as a model organism and found that restoring cardiolipins improved worm health.
Researchers at Max-Planck-Gesellschaft have created a miniature microscope that can capture neural activity in all cortical layers of freely behaving rats. This breakthrough technology allows for continuous imaging of neuron populations, even during complex behaviors, providing insights into the brain's circuit dynamics.