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Rice University


Research yields pricey chemicals from biodiesel waste

Chemical engineers at Rice University have unveiled a set of techniques for cleanly converting glycerin, a major biofuels waste byproduct, into high-value organic acids such as succinate and formate. The new fermentation process uses E. coli bacteria to convert glycerin into these valuable chemicals.

SourceRice University·JournalMetabolic Engineering·DateJun 30, 2008

Nanoparticles aid bone growth

A new study has shown that adding nanoparticles to porous materials can lead to denser bone tissue. Researchers found that the nanoparticles increased bone ingrowth by threefold after 12 weeks compared to a biodegradable plastic scaffold alone. The study paves the way for further research into tissue engineering and bone regeneration.

SourceRice University·JournalBone·DateJun 13, 2008

Cartilage regeneration '20,000 Leagues Under the Sea'

Bioengineers at Rice University have developed a method to stimulate cartilage cell growth using intense pressure, resulting in tissue with nearly all properties of natural cartilage. The new process has potential for treating arthritis and repairing damaged tissues, but further testing is needed.

SourceRice University·JournalPLOS ONE·DateJun 4, 2008

Nanoparticles assemble by millions to encase oil drops

Researchers at Rice University create nanoscale 'baton'-like particles that spontaneously assemble into bag-like sacs around oil droplets in water. This phenomenon could lead to innovative technologies for cleaning up oil spills and polluted groundwater, as well as delivering drugs with controlled release.

SourceRice University·JournalNano Letters·DateMay 29, 2008

Hot climate could shut down plate tectonics

A new study finds that Earth's plate tectonics could become unstable if the surface temperature rises by 100 degrees Fahrenheit or more for a few million years. This would cause the crust to become locked in place, leading to volcanic activity and a lack of tectonic plates moving.

SourceRice University·JournalEarth and Planetary Science Letters·DateMay 12, 2008

Are sacrificial bacteria altruistic or just unlucky?

A genetic study found that chance determines the fate of B. subtilis bacteria, with only a portion producing proteins that benefit the colony and help them form spores. The study used computer simulations to analyze the genes controlling protein production and spore formation.

SourceRice University·JournalMolecular Systems Biology·DateApr 15, 2008

Continents loss to oceans boosts staying power

Geologists found that continents lose around 20% of their mass through chemical weathering involving the Earth's crust, water, and atmosphere. The lighter silicon-rich rock left behind is buoyed up by denser magnesium-rich rock beneath the Earth's crust.

SourceRice University·JournalProceedings of the National Academy of Sciences·DateApr 1, 2008

Astronomers find grains of sand around distant stars

Researchers have found evidence of small, sandy particles orbiting a newborn solar system at a distance similar to the Earth's orbit around the sun. The discovery sheds light on how Earth-like planets may form and offers new opportunities for studying the chemical composition of these particles.

SourceRice University·JournalNature·DateMar 12, 2008

Feds fund study of drug that may prevent radiation injury

A new study funded by the Defense Department aims to develop a drug based on carbon nanotubes to prevent acute radiation injury deaths. The experimental drug, Nanovector Trojan Horses (NTH), has shown promising results in preliminary tests, with mice showing enhanced protection when given first-generation NTH drugs prior to exposure.

New property found in ancient mineral lodestone

Researchers at Rice University have discovered a surprising new electronic property in magnetite, a well-studied magnetic mineral, by using nanofabrication methods. They were able to get the material to revert from an insulator to a conductor at temperatures colder than minus 250 degrees Fahrenheit.

SourceRice University·JournalNature Materials·DateDec 17, 2007

Study: Re-engineered Gleevec reduces heart risks

Researchers re-engineered imatinib to specifically target gastrointestinal stromal tumor and reduce cardiotoxic side effects. The new drug, WBZ-4, was found to be equally effective against gastrointestinal cancer while significantly reducing the risk of heart failure in animal tests.

SourceRice University·JournalJournal of Clinical Investigation·DateDec 3, 2007

Changing environment organizes genetic structure

A study by Deem and Jun Sun found that genetic information becomes increasingly modular when exposed to a changing environment and horizontal gene transfer. This modularity arises spontaneously due to selective pressure, resulting in complex biological structures.

SourceRice University·JournalPhysical Review Letters·DateNov 13, 2007

Proteins pack tighter in crowded native state

A new study from Rice University and the University of Houston found that proteins pack more tightly in their natural environment, with increased structural content and stability. The research suggests that protein structure is affected by crowding, even when proteins are in their folded state.

SourceRice University·JournalProceedings of the National Academy of Sciences·DateNov 12, 2007

Could 'hairy roots' become biofactories?

Rice scientists have successfully grown hairy roots for 4-and-a-half years, a breakthrough that could lead to mass production of medicines like vincristine and vinblastine. The transgenic roots contain genes from both the host plant and bacteria, offering a stable alternative to traditional cell cultures.

SourceRice University·JournalBiotechnology Progress·DateOct 30, 2007

BCM, Rice scientists map flu's chemical key

Researchers at Baylor College of Medicine and Rice University have developed a molecular map of the influenza B virus's hemagglutinin protein. The study reveals similarities between the protein's sequence and function in flu A and B strains, suggesting that minor mutations could enable bird flu to spread among humans.

SourceRice University·JournalProceedings of the National Academy of Sciences·DateOct 15, 2007

Research at Rice may help explain aspects of synesthesia

A Rice University research team has found that damage to the ventrolateral nucleus (VL) of the thalamus can lead to cross-wiring in the brain, resulting in synesthesia. The study, led by Tony Ro, used neuroimaging and behavioral studies on a patient with a rare stroke to demonstrate the VL's role in sensory processing.

SourceRice University·JournalAnnals of Neurology·DateSep 25, 2007

Taxol bristle ball: a wrench in the works for cancer

Researchers at Rice University have discovered a way to load dozens of molecules of the anti-cancer drug paclitaxel onto tiny gold spheres, creating a uniform delivery system that targets cancer cells more effectively. The new approach aims to reduce side effects and improve the effectiveness of chemotherapy.

SourceRice University·JournalJournal of the American Chemical Society·DateSep 12, 2007

New cancer weapon: nuclear nanocapsules

Researchers at Rice University have developed a way to package radioactive particles inside DNA-sized carbon tubes to target tiny tumors. The alpha-emitting nanocapsules are designed to deliver a single, direct hit to cancer cells, making them potentially more effective than traditional beta-particle radiation.

SourceRice University·JournalSmall·DateAug 23, 2007

Which came first, the moth or the cactus?

A rare mutualistic relationship between a moth and cactus in the Sonoran Desert shows that one species can control the population of the other, challenging traditional ecological theory. The research has implications for understanding community ecology and the stability of mutualistic communities.

Zebrafish: It's not your parents' lab rat

A team of researchers at Rice University studied the gene LMO4 in zebrafish, discovering its role in regulating brain growth and development. They found that overexpression of the gene led to shrinkage of brain areas, while underexpression caused their enlargement.

SourceRice University·JournalDevelopmental Biology·DateJul 30, 2007

Nanotube flickering reveals single-molecule rendezvous

Researchers used nanotechnology to study exciton mobility on carbon nanotubes, revealing that each excition travels about 90 nanometers and visits some 10,000 carbon atoms during its lifespan. The unique properties of carbon nanotubes made them an ideal system for observing single-molecule reactions.

SourceRice University·JournalScience·DateJun 7, 2007

Quasicrystals: Somewhere between order and disorder

Quasicrystals, crystal-like materials with atomic structures in between order and disorder, are shown to not conduct electricity like traditional crystals. Mathematician David Damanik offers a key proof for this, revealing that electrons behave uniquely within quasicrystals.

SourceRice University·JournalJournal of the American Mathematical Society·DateMay 23, 2007

Quantum dot recipe may lead to cheaper solar panels

Rice University scientists have developed a breakthrough method for producing molecular specks of semiconductors called quantum dots, which could lead to better and cheaper solar energy panels. The new chemical method produces four-legged cadmium selenide quantum dots with over 90% tetrapod structure.

SourceRice University·JournalSmall·DateMay 2, 2007

'Wrapping' Gleevec fights drug-resistant cancer

A new study finds that the re-engineered Gleevec variant WBZ-7 is effective against both drug-resistant and nonresistant gastrointestinal cancer cells. The wrapping prototype seals out water molecules from a critical area, preventing resistance to the drug, and demonstrates promising results in laboratory studies.

SourceRice University·JournalCancer Research·DateMay 1, 2007

BCM, Rice make major advance in structural biology

Scientists from BCM and Rice University discover a new way to analyze protein movement, making it easier to classify and scrutinize active sites implicated in cancer and other diseases. The breakthrough uses a mathematical algorithm in conjunction with X-ray crystallography to narrow down possible ways a protein might flex and bend.

SourceRice University·JournalProceedings of the National Academy of Sciences·DateApr 30, 2007

Simulated populations used to probe gene mapping

A new study published in PLoS Genetics used computer simulations to trace genetic changes over thousands of generations in a simulated population, testing the effectiveness of statistical genetic methods in identifying multiple genes causing complex diseases. The researchers found that known methods are limited and identified which met...

SourceRice University·JournalPLOS Genetics·DateMar 23, 2007

Nanotube, heal thyself

Researchers discovered that carbon nanotubes can repair themselves by moving blemishes across the surface of the material, sewing up larger holes as they go. This self-repair mechanism allows the nanotube to retain its strength despite severe damage, but comes with a price: releasing energy and mass in the form of gaseous carbon atoms.

SourceRice University·JournalPhysical Review Letters·DateFeb 15, 2007