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Science China Press


Review: Foundation models in bioinformatics

Researchers identified recent advancements in bioinformatics foundation models, enhancing understanding of molecular landscapes and providing practical foundations for innovation in molecular biology. The models are versatile and essential tools for various downstream tasks, including genomics and drug discovery.

SourceScience China Press·JournalNational Science Review·DateFeb 21, 2025

Designing homochiral metal–organic frameworks with ultrahigh surface areas and stability for practical applications

A novel mixed-ligand strategy creates ultrahigh surface area, chemically stable chiral MOFs ideal for practical applications in asymmetric catalysis. The frameworks demonstrate record-breaking surface areas and exceptional structural features, making them suitable as heterogeneous catalysts.

SourceScience China Press·JournalScience Bulletin·TypeExperimental study·DateFeb 21, 2025

Machine learning drives "autonomous" control of particle accelerators

Researchers are using machine learning to enable autonomous control of particle accelerators, opening up new possibilities for commissioning and operating high-power accelerators. The technology has been successfully applied to the CAFe2 superconducting segment, achieving global trajectory adaptive control.

SourceScience China Press·JournalScience China Physics Mechanics and Astronomy·TypeExperimental study·DateFeb 18, 2025

Long-term decline in downward surface solar radiation

A recent study reveals a significant long-term decline in downward surface solar radiation globally, with significant decadal variations observed over land. The research highlights the role of water vapor in DSSR changes, which was previously overlooked, and shows that future DSSR changes will depend heavily on emission scenarios.

SourceScience China Press·JournalNational Science Review·DateFeb 17, 2025

A chemical approach to expand the developmental potentials of conventional human pluripotent stem cells

Scientists discovered a novel method to activate extraembryonic trophoblast potentials in conventional human pluripotent stem cells through transient treatment of epigenetic regulators. This approach holds promise for advancing understanding and treatment of diseases related to placental development.

SourceScience China Press·JournalScience China Life Sciences·TypeExperimental study·DateFeb 14, 2025

Hybrid entanglement carrying orbital angular momentum

The team led by Xiaolong Su prepares hybrid polarization-cat entangled state with OAM degree of freedom, demonstrating non-zero logarithmic negativities for various OAM states. This breakthrough enables increased information capacity in quantum communication and takes a crucial step towards hybrid quantum information processing.

SourceScience China Press·JournalScience Bulletin·TypeExperimental study·DateFeb 14, 2025

Promoter editing enables researchers to develop heat-tolerant cotton germplasms in response to global warming

Researchers use CRISPR/Cas9 and CRISPR/Cpf1 genome editing to precisely edit the promoter region of key high-temperature-responsive gene GhCKI, leading to improved anther development and heat tolerance in cotton. The breakthrough provides novel genetic resources for breeding heat-tolerant cotton varieties.

SourceScience China Press·JournalScience China Life Sciences·TypeExperimental study·DateFeb 10, 2025

Ingenious atomic manipulation induced plainer lattice makes better thermoelectric cooler and power generator

Researchers have developed a new thermoelectric material by introducing copper atoms into commercial n-type Bi₂Te₃-based alloys. This enhances carrier mobility and improves the device's performance, resulting in higher power factor and ZT values. The study's findings hold promise for practical applications in power generation and cooling.

SourceScience China Press·JournalNational Science Review·TypeExperimental study·DateFeb 10, 2025

Fungi’s hidden power: How fungal biomass holds carbon in soil across ecosystems for millennia

This study explores fungal biomass's role in stabilizing carbon in soils, showing a strong correlation between microbial biomass and reactive mineral-associated carbon. Fungal necromass interacts with nanoparticles to further stabilize the carbon after death, proposing a new conceptual model for hypha-mineral interactions.

SourceScience China Press·JournalScience China Earth Sciences·DateFeb 7, 2025

Metabolome and RNA-seq reveal discrepant metabolism and secretory metabolism profile in skeletal muscle between obese and lean pigs at different ages

Researchers identified distinct metabolic profiles in skeletal muscle of Taoyuan Black pig compared to Duroc pig, with correlations to intramuscular fat content and lipid metabolism. The study provides insights into the muscle-adipose axis and potential targets for nutritional regulation.

SourceScience China Press·JournalScience China Life Sciences·TypeExperimental study·DateJan 19, 2025

In-situ magic: A game changer for stabilizing electrode/electrolyte interfaces in aqueous zinc batteries

Scientists introduce a novel approach to construct robust electrode/electrolyte interphase layers on both cathode and anode of aqueous zinc batteries. The use of glutamate additives enables efficient suppression of undesirable side reactions, leading to improved electrochemical performance and cycling stability.

SourceScience China Press·JournalNational Science Review·TypeExperimental study·DateJan 17, 2025

Tracking the atomistic structural transformations in chemical evolution via machine-learned infrared spectroscopy

The study utilizes infrared spectroscopy and a machine-learned protocol to map spectroscopic fingerprints to atomistic structures. The authors demonstrate the accuracy of their network in predicting local atomistic structures and energetic variations, enabling the tracking of dynamic C–C coupling on Cu surfaces.

SourceScience China Press·JournalNational Science Review·DateJan 16, 2025

Supramolecular probes with enhanced phosphorescence properties for biological imaging and sensing

Researchers developed a supramolecular probe with enhanced phosphorescence properties for biological imaging and sensing. The probe demonstrated outstanding stability, biocompatibility, and specificity in viscosity response, enabling real-time visualization of critical physiological processes in cells and in vivo biosensing.

SourceScience China Press·JournalNational Science Review·DateJan 14, 2025

Advances and applications in single-cell and spatial genomics

This review highlights the transformative capabilities of single-cell and spatial genomics, providing critical insights into disease mechanisms and developing innovative therapies. The technologies enable comprehensive cell atlases, tracing the evolution of sequencing methods and incorporating multi-omics approaches, which significantl...

SourceScience China Press·JournalScience China Life Sciences·DateJan 12, 2025