A new nanomedicine, ZnDHT NM, selectively targets cancer stem-like cells (CSCs) and tumor cells, promoting CSC differentiation while inhibiting EMT. This approach also leads to the release of toxic compounds in tumor cells, inducing apoptosis/ferroptosis pathways.
Researchers used Quantum Approximate Optimization Algorithm (QAOA) to cluster jets in high-energy particle collisions, achieving performance comparable to classical algorithms. The study demonstrates the potential of quantum computing in improving jet clustering for practical applications.
The team led by Xiaolong Su prepares hybrid polarization-cat entangled state with OAM degree of freedom, demonstrating non-zero logarithmic negativities for various OAM states. This breakthrough enables increased information capacity in quantum communication and takes a crucial step towards hybrid quantum information processing.
Researchers use CRISPR/Cas9 and CRISPR/Cpf1 genome editing to precisely edit the promoter region of key high-temperature-responsive gene GhCKI, leading to improved anther development and heat tolerance in cotton. The breakthrough provides novel genetic resources for breeding heat-tolerant cotton varieties.
Researchers have developed a new thermoelectric material by introducing copper atoms into commercial n-type Bi₂Te₃-based alloys. This enhances carrier mobility and improves the device's performance, resulting in higher power factor and ZT values. The study's findings hold promise for practical applications in power generation and cooling.
A new buried interface engineering strategy has been proposed to stabilize zinc anodes in aqueous zinc-ion batteries. The approach involves embedding a zincophilic Sn layer within a corrosion-resistant ZnS layer, which accelerates zinc deposition and shields the anode from corrosion.
Researchers identified peri-centrosome-localized siRNAs in C. elegans, which accumulate at the centrosome during cell cycle and are essential for development. The study provides new insights into RNAi-mediated gene regulation in C. elegans.
A study found that excessive Tibetan Plateau spring warming was the primary factor driving catastrophic June 2024 heavy rainfall in southern China. The research used the ESM to simulate extreme warm temperatures over the TP and heavy rainfall in S. China, reproducing approximately 55% of the observed anomaly.
This study explores fungal biomass's role in stabilizing carbon in soils, showing a strong correlation between microbial biomass and reactive mineral-associated carbon. Fungal necromass interacts with nanoparticles to further stabilize the carbon after death, proposing a new conceptual model for hypha-mineral interactions.
Researchers developed high-sensitivity and low-noise infrared superconducting nanowire single-photon detectors, achieving sub-mK temperature resolution. The detectors used photon counting technology, overcoming limitations of conventional semiconductor detectors.
Combustion-related isoprene emissions from outdoor biomass burning and residential fuel use contribute substantially to the formation of wintertime secondary organic aerosols. The study found that combustion-derived isoprene accounts for 25-40% of winter SOA in northern regions.
Researchers have developed a Zn-decorated GaN nanowire catalyst that efficiently converts CO2 and H2O into methane and hydrogen peroxide under light irradiation. The catalyst achieves high conversion rates with 93.6% selectivity and maintains activity for over 80 hours, providing a practical solution for sustainable fuel production.
Researchers successfully tuned the first coordination shell environment of Sb centres to exhibit strong affinity for oxygen reduction, improving catalytic performance. The orbital stabilisation effect mitigates *OH steric hindrance, accelerating formation of *OOH and demonstrating excellent long-term durability.
Researchers analyzed 101 Chinese AML samples and identified three subtypes with different molecular characteristics and clinical outcomes. The study also found potential drug combinations that could improve treatment efficacy for subtype S-II&III patients who benefited from allogenic haematopoietic stem cell transplantation.
China's particulate matter emissions have followed an environmental Kuznets curve, peaking in the mid-1990s. However, finer PM fractions and carbonaceous components have increased due to shifts in industrial energy usage and residential sector transitions. This poses new challenges for air quality policies.
Researchers discovered novel regulatory molecules in adipogenesis, specifically membrane receptors like GPCRs. ADGRD1 promotes differentiation of adipose progenitor cells while GPR39 inhibits this process.
Hainan Island's unique floristic division is a result of its southeast movement since the Oligocene. The island's phylogenetic patterns support an anti-clockwise rotation during this movement, influenced by land bridge connections with China mainland after the Middle Miocene.
Researchers developed a metal-organic cage that selectively recognizes and encapsulates radioactive strontium, achieving a 99.7% removal efficiency at low concentrations. The novel material design enables precise recognition sites within the cage's cavity.
Researchers identified distinct metabolic profiles in skeletal muscle of Taoyuan Black pig compared to Duroc pig, with correlations to intramuscular fat content and lipid metabolism. The study provides insights into the muscle-adipose axis and potential targets for nutritional regulation.
Researchers have revived the Lieb-Schultz-Mattis theorem in open quantum systems, extending its constraints to entanglement Hamiltonian and shedding light on behavior of entanglement in presence of environment. The theorem requires weak symmetry and short-range correlation, with numerical simulations verifying its validity.
Scientists have created a stable 2D material, InSbMoO6 (ISM), using lone pair electrons as chemical scissors. ISM exhibits strong nonlinear optical responses and good air stability, making it promising for integrated photonics applications.
Scientists introduce a novel approach to construct robust electrode/electrolyte interphase layers on both cathode and anode of aqueous zinc batteries. The use of glutamate additives enables efficient suppression of undesirable side reactions, leading to improved electrochemical performance and cycling stability.
The study utilizes infrared spectroscopy and a machine-learned protocol to map spectroscopic fingerprints to atomistic structures. The authors demonstrate the accuracy of their network in predicting local atomistic structures and energetic variations, enabling the tracking of dynamic C–C coupling on Cu surfaces.
Researchers developed a supramolecular probe with enhanced phosphorescence properties for biological imaging and sensing. The probe demonstrated outstanding stability, biocompatibility, and specificity in viscosity response, enabling real-time visualization of critical physiological processes in cells and in vivo biosensing.
New research reveals viruses play a significant role in carbon, nitrogen, and phosphorus cycles. Viral aggregation is proposed to describe the accumulation of lytic products in soil/sediment environments.
Temperate savannas in eastern China have been mapped for the first time, revealing their geographical distribution and extent. The research provides precise information on the spatial characteristics of these ecosystems, supporting conservation and utilization efforts.
This review highlights the transformative capabilities of single-cell and spatial genomics, providing critical insights into disease mechanisms and developing innovative therapies. The technologies enable comprehensive cell atlases, tracing the evolution of sequencing methods and incorporating multi-omics approaches, which significantl...
The study introduces a novel framework that accurately predicts global warming caused by greenhouse gas emissions without relying on complex climate models. It confirms human-caused greenhouse gas emissions drive observed global warming, independently of conventional approaches.
TEGO's three-dimensional tetrahedral structure improves stability and reliability through redundancy and stable center of mass. The configuration also enables the detection of six polarization modes simultaneously, expanding our understanding of gravitational waves.
Researchers developed a 3D contactless solar evaporation design to enhance heat and mass transport, achieving high evaporation rates and improved scalability. The design's performance variation between small and large devices is minimal, making it suitable for diverse water treatment scenarios.
Overexpressing hepatic SLC7A11 leads to glutamate and serine deficiency, promoting MASLD progression through ferroptosis. Serine supplementation rescues the disease phenotype.
Long-term drainage increases bound OC% in non-Sphagnum wetlands due to reactive metal oxides, but decreases it in Sphagnum wetlands. This mechanism helps compensate for lost unbound SOC components in non-Sphagnum wetlands.
Researchers designed metallo-supramolecular complexes that selectively bind to MPXV mRNA G4, modulating A5L protein expression and immune response activation. These findings highlight the significance of G4s in viral immunodominant protein expression and offer potential avenues for developing antiviral therapeutics.
Researchers observe quantum oscillations in CaAs3 near the Mott-Ioffe-Regel limit, showing strong electronic coherence despite insulating behavior. The findings challenge conventional theories and offer a new perspective on quasiparticle coherence.
Researchers have synthesized a novel hydride superconductor A15-La4H23 and observed an unusual metallic state under strong magnetic field conditions. The maximum superconducting critical temperature of 105 K was achieved with the pressure of 118 GPa, expanding our understanding of transport behavior in hydride superconductors.
The one-core-neuron system (OCNS) minimizes model size while maintaining high performance in deep learning. OCNS employs a single neuron to encode high-dimensional data into a one-dimensional time-series representation, reducing parameters by an average of 0.035%.
A new study reveals fossilized chewing lice eggs in mid-Cretaceous amber, associated with enantiornithine feathers. The discovery provides insight into early coevolution between bird hosts and ectoparasites, shedding light on the origins of modern lice.
These materials integrate liquids within solid frameworks at the mesoscale, driven by competitive interfacial interactions. They demonstrate dynamic responsiveness leveraging force, heat, light, electricity, magnetism, and sound, and exhibit practical functionalities including anti-fouling and multiphase flow control.
Researchers demonstrated a novel mechanism for generating ultrafast spin currents above the Curie temperature in 2D magnetic materials using laser-enhanced proximity effect. This discovery enables the creation of terahertz radiation and opens up new possibilities for spintronics.
A new study has developed a platinum-based catalyst that can efficiently convert CO2 into valuable chemicals, with improved stability in acidic media. The catalyst, PtNPs@Th, was created by encapsulating thionine molecules within platinum nanocrystals, resulting in enhanced catalytic activity and corrosion resistance.
Exposure to triclocarban, a common antibacterial agent, promotes myocardial hypertrophy in human cardiac organoids. The study found that TCC interferes with endothelial cell metabolism, leading to nitrosative stress and inflammation. This new mechanism suggests a potential treatment target for myocardial hypertrophy.
A team of researchers discovered supra-thermal DT ions beyond Maxwellian distributions in ICF burning plasmas. The new hybrid model predicts a ~10 ps ignition moment promotion, enhanced alpha particle densities at the hotspot center, and the presence of supra-thermal D ions below 34 keV.
Researchers develop coprecipitation method to create free-standing porous carbon fibers with Zn single atom sites and molybdenum carbide clusters, enhancing iodine adsorption and electrocatalytic activity. The resulting zinc-iodine batteries demonstrate high specific capacity and good capacity retention.
Researchers propose using Exo-AUVs to detect life on Icy Worlds like Europa by identifying micro-zones with high biological potential. The strategy guides the Exo-AUV to collect diverse robust biosignatures and potentially detect extant life in various dimensions.
Scientists have successfully demonstrated an integrated spin-wave quantum memory, enabling on-demand retrieval with adjustable storage times. The device outperforms previous methods, achieving a fidelity of 94.9% in storing and retrieving single-photon-level inputs.
Developed by Dr. Cheng-Hui Li and Dr. Pengfei Zheng, the material combines low modulus and high toughness while replicating natural muscle functions, offering great potential in prosthetic actuators and tissue engineering applications.
Compound low-solar-low-wind (LSLW) extremes in China are expected to increase nationwide, threatening the country's renewable energy supply. The Tibetan Plateau and northwestern China face high LSLW frequency, while grid interconnection can mitigate impacts by over 91%.
A recent study analyzed genomic variation distribution, genetic diversity, and heterotic group types in modern maize inbred lines. The research found new potential heterotic groups and identified elite breeding loci for traits like yield, plant architecture, and stress resistance.
Researchers discovered supra-thermal DT ions beyond Maxwellian distributions in burning plasmas of inertial confinement fusion. The findings, achieved through innovative modeling and simulations, challenge existing models and offer new insights into the physics of these extreme conditions.
A team of researchers developed a machine learning framework to streamline the discovery of high-performance ionic thermoelectric materials. The approach predicted Seebeck coefficients with high accuracy and identified critical molecular descriptors influencing material performance.