Research finds that brain iron levels increase during childhood and adolescence, correlating with improved cognitive abilities. Decreased iron levels in certain brain regions are associated with impaired performance on cognitive tasks, highlighting the importance of iron for healthy brain development.
Neurogenesis has been shown to have an additional role beyond learning and memory, with adult neural stem cells involved in regeneration. In a study published in JNeurosci, mice were exposed to a toxic substance that damaged the dentate gyrus, but recovered almost fully through neurogenesis.
Research in fruit flies found that environmental light exposure activates light-sensitive neurons, triggering the production of memory maintenance proteins. This study suggests that long-term memories require active maintenance through natural lighting conditions.
Researchers found that brain activity in healthy adults synchronized with sound waves produced by a silent woman speaking, indicating the brain can process auditory information from visual cues. This ability arises from visual cortex activity synchronizing with lip movement and signal transmission to other areas for sound synthesis.
Research in mice suggests that short chain fatty acid supplementation can improve stroke recovery, reducing motor impairment and increasing spine growth on dendrites. The gut-brain connection plays a crucial role in this process, with microglia activity linked to improved stroke outcome.
Research shows that drawing and recognizing objects recruits the same neural representation in the brain, emphasizing the role of visual processing. This neural connection enhances over time with repeated practice.
Research found that high fat diets limit newborn and developing neurons in adult female mice, but not males, potentially linking metabolic disorders to brain disorders like Alzheimer's disease. The study may inspire metabolism-based preventions and treatments.
Research on mice suggests that antidepressant exposure during pregnancy can lead to long-term changes in brain activity and sensory processing. The study found abnormal brain activity in sensory areas of fluoxetine-exposed mice when stimulated with their front paws.
A recent study identified distinct gene signatures associated with memory creation, found in cortical and subcortical regions of the brain. These genes play crucial roles in memory processes, immune signaling, neuronal generation, and mRNA production.
A ketone-supplemented diet has been shown to restore protective protein levels and decrease mortality rates in mice with Alzheimer's disease. By consuming a diet rich in ketones, the mice experienced fewer seizures and were less likely to die, suggesting that this intervention may help protect interneurons from damage.
Recent research suggests that gender dysphoria may be caused by altered activity in the distress, social behavior, and body-ownership networks. This new theory challenges the existing understanding of the condition.
Researchers found that rats susceptible to depression had more serotonin neurons after chronic stress, but these effects could be reversed through amygdala activation. In contrast, resilient rats showed no significant change in serotonin levels under stressful conditions.
A study analyzing data from four types of mouse Alzheimer's models found consistent changes in cell number and gene expression throughout the disease stages. The research provides new targets for intervention and therapy, highlighting the immune system's involvement in early stages of Alzheimer's.
Research in mice found that environmental enrichment can partially correct mis-mapped neurons in the visual pathway, leading to vision issues in adulthood. Mice raised in enriched environments showed less mapping errors than those in standard cages.
A new study found that ketamine decreases alcohol consumption in high-consuming male rats, but has no effect on females. The drug may be a viable treatment option for male patients with an alcohol use disorder.
Research reveals that adolescent binge drinking can lead to altered gene expression, increasing susceptibility to anxiety and alcohol use disorders in adulthood. Targeting specific microRNAs may be a new approach to undoing the damage of early-life alcohol exposure.
Research on newborn rats suggests that fetal nicotine exposure may impair the function of neurons controlling the tongue, leading to difficulty breathing. This impairment could be a factor in sudden infant death syndrome (SIDS) in humans.
Researchers found that pioglitazone reduces physical and emotional nicotine withdrawal symptoms in rats and mice. The study suggests that the diabetes drug may help diabetic smokers quit by reducing insulin resistance and alleviating anxiety associated with nicotine withdrawal.
Research published in JNeurosci found that fetal brains possess adult-like networks by 20-40 weeks gestation. The study discovered a 61% overlap in motor, visual, auditory, and cognitive functions between fetal and adult connectomes.
Research in mouse neurons reveals that misfolded tau protein can quickly spread between neurons without being immediately harmful. Early therapeutic intervention targeting the initial accumulation of tau may halt Alzheimer's disease progression.
Researchers have made significant advancements in understanding olfactory perception and processing, highlighting the role of dynamic features, sniffing speed, and odorous landmarks in guiding behaviors like navigation and finding resources. The study's findings provide new insights into how the brain represents smells and its importan...
The study explores how behaviors like empathy and team flow are represented in the brain, shedding light on conditions such as autism spectrum disorder and social anxiety. Brain imaging reveals specific neural circuits involved in social behaviors, providing potential new avenues for researching these complex processes.
Recent advances using lab-grown brain organoids have improved understanding of human brain development and diseases. However, questions remain about how well these brain models mirror the complexity of the cortex. Studies show that organoids can reproduce a rich diversity of cell types found in the cerebral cortex, but fail to capture ...
Researchers have made significant breakthroughs in understanding the role of microglia in neuroinflammation, a hallmark of degenerative brain diseases such as Alzheimer's Disease. Studies show that changes in microglial cells can trigger hyperexcitability in the brain, leading to decreased sociability and motivation.
Listeners prefer songs with balanced uncertain expectations, suggesting a 'reward for learning'. Medium complexity musical fragments with counterbalancing uncertain and predictable events yield the highest preference ratings.
Studies of autism spectrum disorder have identified new features of the condition in the brain, including the role of placental hormones and gene editing technologies. These findings may contribute to the development of therapeutic treatments for individuals with ASD.
New approaches in transcriptomics are providing single cell views of brain development and disease, including cellular processes associated with addiction and degeneration. These studies highlight the potential of transcriptomics to probe molecular changes within brain cells during normal development or diseases such as Alzheimer's and...
Studies show intestinal bacterial imbalance linked to neurodegenerative diseases like Alzheimer's Disease and traumatic brain injury. Probiotics may improve brain function by altering the gut microbiome, reducing amyloid beta plaque and memory deficits.
Research reveals a connection between Alzheimer's disease and metabolic disturbances, including glucose resistance and abnormal sleep patterns. Introducing ApoE2 into cells expressing ApoE4 may reduce metabolic deficiencies, supporting cellular functions and energy metabolism in the brain.
Researchers found gene therapy potential in treating neurological disorders like Alzheimer's disease, amyotrophic lateral sclerosis, and Parkinson's disease. New therapeutic approaches reprogram glial cells into motor neurons and deliver antibodies to protect against toxins.
The development of neural-digital interfaces raises concerns about equality, identity, security, privacy, and access. The roundtable explores societal and ethical issues surrounding these technologies.
Neuro Space is an immersive installation that reimagines how scientists view neurons through the intersection of art and technology. The exhibit explores the power of art to reflect scientific structures and illuminates the vastness of what remains unknown in neuroscience.
Research reveals brain areas can be repurposed to process information from unrelated body parts, contradicting previous assumptions about body map limitations. Functional MRI scans showed unused hand regions activated by movements of other body parts, suggesting a more dynamic and adaptable brain network.
Researchers used repetitive transcranial magnetic stimulation to increase functional connectivity of a neural network implicated in memory. The study, published in eNeuro, confirms the effectiveness of this technique for experimental and clinical applications.
Researchers found a neural pathway that links adult rats' preference for stressed juveniles, triggering parental instincts. This parallels humans' empathy towards children over peers.
Research investigates how diet and excess blood glucose influence Alzheimer's pathology, providing new insights into the link between diabetes and Alzheimer's disease. The study aims to develop therapies targeting glucose pathways, offering potential treatments for this debilitating condition.
Scientists discuss strengths and weaknesses of organoids as a model for human cortex, employing them to study developmental brain disorders. Researchers explore the viability of mini-brains in clinical research.
Researchers detect non-linguistic experience in brain activity during reading, combining with linguistic information to decode sentence meaning. This breakthrough may guide future efforts in language disorders and artificial intelligence.
A larger sample size failed to support original claims linking genetic variants to altered brain activation during reading and listening. The new findings highlight the complexity of genes and human brain function relationships.
Research reveals how CBD inhibits emotional processing in rats exposed to THC, reducing anxiety behaviors. The study proposes a bi-directional control of ERK1-2 phosphorylation as the key mechanism behind these findings.
Researchers at Neuroscience 2019 announce new gene therapy research promising to prevent, treat, and reverse incurable neurological disorders. Successes in restoring lost functions in animal models of neurological diseases are discussed, as well as technique advancements that may improve future treatments.
Research found that 65% of visual cortex regions in blind individuals show synchronized activity when listening to audio clips, indicating a higher-order processing role. The study suggests an underlying organization dictates the brain's repurposing of unused regions in blind people.
A new study reveals that a protein called caveolin-1 (Cav-1) is depleted in the temporal lobe of humans with type-2 diabetes and in a diabetic mouse model, leading to increased Alzheimer's disease pathology. Restoring Cav-1 levels in mice reduced Alzheimer's pathology and improved learning and memory deficits.
Research published in eNeuro found that female mice isolated during adolescence showed atypical brain development and habitual behavior in adulthood. Social isolation was linked to dendritic spine excess and impairment of goal-dependent decision making, highlighting the importance of social experience during adolescence.
A new study reveals that listening to music involves activity in sensory regions, while recalling melodies activates frontal regions. The findings suggest a complex network of brain regions involved in music processing.
Research in mice reveals that chronic cocaine use changes gene expression in the hippocampus, leading to epigenetic modifications of the FosB gene. This modification enables the formation of drug associations and contributes to addiction.
New research reveals that human selective breeding has altered dog brain structure and behavior, with breeds exhibiting unique brain networks correlated to specific characteristics.
Research in forager honeybees suggests that changes in a vibration-sensitive neuron enhance waggle dance communication. The older bees demonstrate more precise connections to other brain regions and better signaling, allowing them to effectively convey information through the waggle dance.
Research found that social and executive brain functions are essential for successful language processing, even in individuals with dementia. Patients with frontotemporal dementia performed poorly on language tests despite showing no speech impairment, highlighting the importance of non-language brain regions.
Researchers found that remote ischemic limb conditioning increased inflammatory cells in circulation, reducing brain tissue damage and swelling while improving motor function. The technique has potential for treating strokes of varying severity, offering hope for improved recovery outcomes.