Researchers used machine learning to analyze nationwide health checkup records and identified a reliable method for predicting diabetes patients. The model accurately predicted future incidence of diabetes with an overall accuracy of 94.9%.
A new study published in the Journal of the Endocrine Society found that people with very poor fitness at the beginning of a behavioral weight loss program lose less weight in the long term. Adults with poor or better fitness lost nearly twice as much weight over 18 months compared to those with very poor fitness.
Researchers discovered that activating the androgen receptor decreases tumor growth in estrogen receptor-positive (ER+) breast cancer. The study used enobosarm, an androgen receptor-stimulating drug, which stopped tumor growth in all models tested.
A new study found that artificial intelligence (AI) can accurately identify patients at risk of osteoporosis and fractures by analyzing electronic radiology reports, outperforming traditional manual methods. The AI tool, XRAIT, detected a significant number of major fractures, improving patient outcomes and reducing the burden of illness.
A new study links pregnant women's PFAS exposure to their granddaughters' increased obesity risk. The research found that higher levels of PFAS in grandmothers were associated with a greater risk of obesity in granddaughters, even when controlling for other factors.
A study published by the Endocrine Society found that patients with diabetes are more likely to lose meibomian glands in their eyelids, which may be a sign of elevated blood glucose levels. This could lead to a new biomarker for diagnosing diabetes and tracking average blood glucose levels.
A study found that people with type 2 diabetes who have a lacunar stroke experience better cognitive function when their glucose levels are well-controlled. This association remains significant even after adjusting for other factors.
A study analyzing 6 million days of real-world data shows the MiniMed 670G system can maintain target glucose range of 70-180 mg/dL over 71% of the time. The AutoMode feature improves glycemic control, reducing low and high blood sugar episodes.
The REVITA-2 study found that Revita DMR therapy significantly improved blood glucose levels, insulin sensitivity, and liver measures in patients with poorly controlled type 2 diabetes. The treatment, which involves duodenal mucosal resurfacing, reduced insulin resistance and improved metabolic health.
A new study published in the Journal of the Endocrine Society found that chemicals such as bisphenol A (BPA) substitutes can affect fetal development and lead to hypertension in later life. The research, conducted on pregnant rats, suggests that even low-dose exposure to these chemicals can impact blood pressure later in life.
A recent study suggests that bariatric surgery performed before developing diabetes results in greater weight loss. Patients without diabetes achieved a higher chance of successful weight loss compared to those with diabetes, with diabetes diminishing weight loss by 1.2 BMI points.
A team of international medical experts successfully delivered insulin via a drone to a patient living in a remote community in Ireland, addressing healthcare access issues. The project demonstrated the potential for autonomous drones to deliver life-saving medications and supplies in disaster scenarios.
A new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that eating a large breakfast instead of a large dinner creates twice as high diet-induced thermogenesis. This process measures how well metabolism is working, and can differ depending on mealtime.
A new study by The Endocrine Society reveals that women with polycystic ovary syndrome (PCOS) suffer from poor health and quality of life in their late forties, primarily due to ongoing mental health concerns. Women with PCOS have lower life satisfaction and poorer health compared to those without the condition.
Research published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that teens with obesity and PCOS have an altered gut microbiome compared to those without the condition. This altered microbiome is associated with higher testosterone levels, metabolic complications, and other health risks.
Researchers found that measuring anti-Müllerian hormone (AMH) levels can predict when a woman's final menstrual period will occur. AMH serves as an indicator of remaining egg supply, decreasing with age. This new test allows for more accurate predictions within 12 to 24 months in women's late 40s and early 50s.
A new study found that over 24 routine blood tests are affected by childhood obesity, including liver function tests and inflammation markers. This discovery could help doctors better interpret test results and provide more accurate diagnoses.
The Endocrine Society and Avalere Health introduced quality measures to assess healthcare providers' ability to identify and care for older adults at risk of hypoglycemia. The measures focus on outpatient treatment for adults aged 65 and older with type 2 diabetes, highlighting key risk factors and emphasizing education to prevent futu...
Research published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that older adults with hypothyroidism are 26% more likely to die from all causes than their peers without the condition. However, this increased risk was not observed in individuals with milder forms of thyroid disease.
Researchers found that adjusting CGM alarm settings can inform patients about high or low blood sugar events early, enabling timely treatments. The study suggests simpler adjustments to these thresholds could lead to better management of hypo- and hyperglycemia for people with type 1 diabetes.
The Endocrine Society calls for evidence-based approaches to transgender healthcare, citing the risks of denying care. The organization's Clinical Practice Guideline recommends avoiding hormone therapy for transgender children prior to puberty.
Advances in medications, lifestyle changes, and technologies can help manage post-meal blood sugar levels, but more research is needed to pinpoint a target range and improve clinical outcomes. Small lifestyle changes, such as eating protein and vegetables before carbohydrates, can also lower blood glucose levels.
A recent study published in the Journal of the Endocrine Society suggests that vaping may have negative effects on fertility in young women. The research found that exposure to e-cigarettes during pregnancy can delay implantation of a fertilized embryo, thereby reducing fertility. Additionally, the study discovered that female offsprin...
The Endocrine Society and international partners endorse a statement clarifying benefits and risks of testosterone therapy for women. Testosterone therapy has been shown to improve sexual wellbeing in postmenopausal women with Hypoactive Sexual Desire Dysfunction (HSDD), reducing concerns and distress about sex.
Research reveals lavender oil exposure contributes to premature breast development in young girls and boys. Discontinuing use of lavender-containing products resolves the issue, suggesting essential oils mimic estrogen and block testosterone.
The Endocrine Society recommends regularly screening older adults for heart disease and diabetes risk, prioritizing lifestyle modification as the first-line therapy. Patients with at least three metabolic risk factors should be screened annually, while those with one or two risk factors should be screened every three years.
A study published by The Endocrine Society found that exposure to bisphenol S (BPS) and bisphenol F (BPF) in plastics and canned foods may contribute to childhood obesity. Children with higher levels of these chemicals in their urine were more likely to have obesity compared to those with lower levels.
A nationwide study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that high blood sugar levels significantly increase the risk of pancreatic cancer. The study suggests that early detection of hyperglycemia and lifestyle modifications to improve glucose profiles may help lower this risk.
A large population-based study found that antidepressants significantly reduced mortality by 35% in patients with diabetes and depression. This significant reduction highlights the importance of addressing depression in individuals with diabetes, a condition where two to three times more people are at risk of depression.
A recent study published by The Endocrine Society found that women exposed to triclosan are more likely to develop osteoporosis. The study analyzed data from over 1,800 women and discovered that those with higher levels of triclosan in their urine were more prone to bone issues.
A mouse study published in the Endocrine Society's journal Endocrinology found that BPA exposure may contribute to autism by disrupting nerve cell connections in the brain. Mice exposed to BPA during pregnancy showed social behavioral deficits similar to autistic behavior.
A nationwide study found patients with diabetes discharged with low glucose values have a higher risk of death and rehospitalization; physicians should avoid discharging patients until glucose levels are above 100 mg/dl
Researchers found 18 babies with ambiguous genitalia among 14,177 newborns, a frequency higher than previous studies. Lower birth weight was also linked to the condition, with preeclampsia common in those pregnancies.
The Annovera vaginal ring, approved by the FDA last August, is a self-inserted system that provides contraceptive efficacy for up to 13 cycles (1 year) of use. It has a Pearl index of 2.98, indicating only about three unintended pregnancies per 100 women in a year.
A new automated drug delivery system can detect impending low blood sugar and deliver glucagon to prevent severe hypoglycemia in patients with post-bariatric hypoglycemia. The study found the system was effective in improving blood glucose levels after meals and reducing severe hypoglycemia.
A new study from Australia found that older men with higher levels of sex hormones, particularly estradiol, have lower biological age. This association remained true even after adjusting for age, lifestyle factors, and medical conditions.
Research presented at ENDO 2019 found that walking downhill after eating reduces bone resorption in postmenopausal women with diabetes. The study suggests combining exercise after meals with downhill walking may help reduce the need for osteoporosis medication.
Researchers discovered a novel molecular pathway for PAI-1 inhibition that reversed diet-induced obesity and its related health problems in mice. The investigational drug TM5614 showed significantly improved fasting levels of blood sugar, insulin, and LDL cholesterol, as well as a reduction in fatty liver disease.
A mouse study suggests that time-restricted eating can delay the development of tumors and reduce tumor growth in obese mice with high-fat diets. The results imply that this intervention could be effective in preventing breast cancer.
A study found that estradiol hormone therapy helps strengthen brain connections in transgender women, particularly in the thalamus area. This can lead to improved symptoms like hot flashes and sensory perception.
The Endocrine Society's Clinical Practice Guideline recommends treating postmenopausal women with pharmacological therapies to reduce fracture risk, outweighing the risks of rare side effects. Guidelines also provide recommendations for monitoring and reassessing fracture risk after initial treatment.
A new study suggests that white women with polycystic ovary syndrome (PCOS) experience higher levels of anxiety compared to their black counterparts. The research found a significant difference in anxiety symptoms between the two groups, with white women exhibiting higher rates of anxiety on screening tests.
A new male oral contraceptive, 11-beta-MNTDC, has been found to decrease sperm production while preserving libido, according to a phase 1 study. The drug produced hormone responses consistent with effective contraception and had few mild side effects.
Researchers found that men who stopped using performance-enhancing hormones experienced complete recovery of sperm production and hormone levels within nine to 18 months. However, testicular size remained smaller than normal in some cases. The study provides valuable insights for endocrinologists caring for men affected by androgen abuse.
Men with hypogonadism and obesity who received long-term testosterone therapy achieved progressive and sustained weight loss, while untreated controls gained. Testosterone-treated men also experienced reductions in mortality and major cardiovascular events.
A new study found that endocrine disruptors can alter female reproduction and sexual development in offspring, affecting reproductive health throughout multiple generations. The researchers observed delayed puberty, abnormal cycles, and ovulation in third- and fourth-generation females.
Research in mice found that exposure to particulate matter led to deterioration of testicular function and changes in gene expression related to sperm production. The study's findings suggest that air pollution may be a contributing factor to the increasing rates of male infertility worldwide.
A new study suggests that the adipose hormone aP2 is associated with obesity-related asthma and may be a key factor in its development. Higher levels of aP2 were found in people with overweight or obesity who also had asthma, suggesting a potential link between the two conditions.
Research found that HIV-exposed but uninfected (HEU) adolescents and young adults are at higher risk of obesity and reactive airway disease compared to their non-exposed peers. Lower prenatal maternal CD4 count was associated with increased body mass index (BMI) in HEU adolescents.
A new clinical trial found that burosumab significantly improves rickets and related outcomes in children with X-linked hypophosphatemia compared to conventional therapy. The study, which included 61 children, showed substantial healing of rickets in 72% of participants who received burosumab.