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University of California - Los Angeles


UCLA-led study challenges bipolar depression treatment guidelines

A UCLA-led study found that individuals with bipolar depression who continued taking antidepressants in conjunction with mood stabilizer medication after remission had a lower risk of depression relapse. The study's lead author, Dr. Lori Altshuler, suggests guidelines similar to those for unipolar depression may be more effective.

SourceUniversity of California - Los Angeles·JournalAmerican Journal of Psychiatry·DateJul 1, 2003

UCLA physicists create nanoscale sensor

Giovanni Zocchi's team has created a nanoscale sensor that can detect specific genetic markers in DNA or RNA molecules with high sensitivity. The sensor uses evanescent wave scattering to analyze the conformational changes caused by target molecule binding, allowing for precise detection of single molecules.

SourceUniversity of California - Los Angeles·JournalProceedings of the National Academy of Sciences·DateJun 19, 2003

Drug that cuts off a tumor’s blood supply shows promising results when paired with chemotherapy

Researchers have discovered that combining Avastin with chemotherapy provides superior treatment for advanced colorectal cancer, increasing median survival by 8.3 months and response rates. The study's findings suggest a more effective and less toxic option for patients with this devastating form of cancer.

SourceUniversity of California - Los Angeles·JournalJournal of Clinical Oncology·DateDec 28, 2002

Sleep apnea linked to early brain damage

Researchers found dramatic gray matter loss in the brains of men with sleep apnea, primarily in regions controlling speech production, movement, and emotion. The severity of brain damage correlated directly with disorder severity, suggesting that early brain wiring abnormalities may contribute to sleep apnea onset.

SourceUniversity of California - Los Angeles·JournalAmerican Journal of Respiratory and Critical Care Medicine·DateNov 20, 2002

UCLA scientists eavesdrop on cellular conversations by making mice 'glow' with firefly protein

Researchers use firefly protein to visualize cellular communication pathways in mice, revealing potential for non-invasive cancer treatment and disease research. This breakthrough enables scientists to watch proteins in their natural setting, improving understanding of human diseases.

SourceUniversity of California - Los Angeles·JournalProceedings of the National Academy of Sciences·DateNov 13, 2002

People near freeways are exposed to 30 times the concentration of dangerous particles

Research reveals that people near freeways are exposed to 30 times more ultrafine particles, linked to neurological changes and cardiovascular problems. The study measured particle concentrations near two major freeways in Los Angeles, finding a significant decrease in particle concentration with distance from the freeway.

SourceUniversity of California - Los Angeles·JournalJournal of the Air & Waste Management Association·DateOct 17, 2002

UCLA AIDS Institute scientists show antiretroviral drugs can eradicate AIDS epidemic

A UCLA study found that treating more people in developing countries with antiretroviral drug therapy can eliminate HIV on a community level, even without eradicating it in individuals. The research suggests that treatment and prevention are not two separate approaches, but rather intertwined strategies to save lives.

SourceUniversity of California - Los Angeles·JournalThe Lancet Infectious Diseases·DateAug 1, 2002